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Sella turcica neoplasm

MedGen UID:
148188
•Concept ID:
C0748616
•
Neoplastic Process
Synonyms: Neoplasm of Sella Turcica; neoplasm of sella turcica; Neoplasm of the Sella Turcica; neoplasm of the sella turcica; Neoplasm of the Sellar Region; Sella Turcica Neoplasm; sella turcica neoplasm; Sella Turcica Tumor; sella turcica tumor; sella turcica tumour; Sellar Neoplasm; sellar neoplasm; Sellar Region Neoplasm; Sellar Tumor; sellar tumor; sellar tumour; selt; tumor of sella turcica; Tumor of the Sella Turcica; tumor of the sella turcica; Tumor of the Sellar Region; tumour of sella turcica; tumour of the sella turcica
 
Monarch Initiative: MONDO:0002720

Definition

A benign or malignant neoplasm that occurs in the sellar region. Representative examples include craniopharyngioma and pituitary gland adenoma. [from NCI]

Professional guidelines

PubMed

Differential Diagnosis and Radiographic Imaging of Pituitary Lesions: An Integrated Approach.
Zhao K, Nimchinsky E, Agarwalla PK
Otolaryngol Clin North Am 2022 Apr;55(2):247-264. Epub 2022 Mar 4 doi: 10.1016/j.otc.2021.12.002. PMID: 35256172
Diagnosis and Treatment of Parasellar Lesions.
Gatto F, Perez-Rivas LG, Olarescu NC, Khandeva P, Chachlaki K, Trivellin G, Gahete MD, Cuny T; on behalf of the ENEA Young Researchers Committee (EYRC)
Neuroendocrinology 2020;110(9-10):728-739. Epub 2020 Mar 4 doi: 10.1159/000506905. PMID: 32126547
Treatment strategies for craniopharyngiomas.
Ottenhausen M, Rumalla K, La Corte E, Alalade A, Nair P, Forbes J, Ben Nsir A, Schwartz TH
J Neurosurg Sci 2019 Feb;63(1):83-87. Epub 2017 Sep 4 doi: 10.23736/S0390-5616.17.04171-6. PMID: 28869375

Recent clinical studies

Etiology

Histopathology of Parasellar Neoplasms.
Manojlovic-Gacic E, Rostami E, Karavitaki N, Casar-Borota O
Neuroendocrinology 2020;110(9-10):740-752. Epub 2020 Mar 11 doi: 10.1159/000507084. PMID: 32155632Free PMC Article
Nonneuroendocrine Neoplasms of the Pituitary Region.
Kaltsas GA, Kolomodi D, Randeva H, Grossman A
J Clin Endocrinol Metab 2019 Aug 1;104(8):3108-3123. doi: 10.1210/jc.2018-01871. PMID: 30779850
Sellar and Parasellar Pain Syndromes.
Abad AP
Curr Pain Headache Rep 2019 Feb 2;23(1):7. doi: 10.1007/s11916-019-0740-x. PMID: 30712067
Tuberculum sella meningioma.
Hayhurst C, Teo C
Otolaryngol Clin North Am 2011 Aug;44(4):953-63, viii-ix. doi: 10.1016/j.otc.2011.06.012. PMID: 21819882
Intrasellar arachnoid cysts.
Dubuisson AS, Stevenaert A, Martin DH, Flandroy PP
Neurosurgery 2007 Sep;61(3):505-13; discussion 513. doi: 10.1227/01.NEU.0000290896.69825.40. PMID: 17881962

Diagnosis

Ectopic Pituitary Neuroendocrine Tumors/Adenomas Around the Sella Turcica.
Demir MK, Ertem Ö, Kılıç D, Akıncı O, Ecertaştan Ö, Konya D, Kılıç T
Balkan Med J 2024 May 3;41(3):167-173. Epub 2024 Mar 8 doi: 10.4274/balkanmedj.galenos.2024.2023-11-90. PMID: 38454561Free PMC Article
Imaging of the sellar and parasellar regions.
Jipa A, Jain V
Clin Imaging 2021 Sep;77:254-275. Epub 2021 Jun 8 doi: 10.1016/j.clinimag.2021.05.022. PMID: 34153590
Neuroimaging of the Pituitary Gland: Practical Anatomy and Pathology.
Chapman PR, Singhal A, Gaddamanugu S, Prattipati V
Radiol Clin North Am 2020 Nov;58(6):1115-1133. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.009. PMID: 33040852
Nonneuroendocrine Neoplasms of the Pituitary Region.
Kaltsas GA, Kolomodi D, Randeva H, Grossman A
J Clin Endocrinol Metab 2019 Aug 1;104(8):3108-3123. doi: 10.1210/jc.2018-01871. PMID: 30779850
Sellar Lesions/Pathology.
Bresson D, Herman P, Polivka M, Froelich S
Otolaryngol Clin North Am 2016 Feb;49(1):63-93. doi: 10.1016/j.otc.2015.09.004. PMID: 26614829

Therapy

Prolactinomas.
Wildemberg LE, Fialho C, Gadelha MR
Presse Med 2021 Dec;50(4):104080. Epub 2021 Oct 21 doi: 10.1016/j.lpm.2021.104080. PMID: 34687915
Diabetes Insipidus: To Treat or Not to Treat?
Nguyen C, Sirineni G
Int J Radiat Oncol Biol Phys 2021 Mar 1;109(3):651-652. doi: 10.1016/j.ijrobp.2019.09.024. PMID: 33516432
Pituitary incidentaloma.
Orija IB, Weil RJ, Hamrahian AH
Best Pract Res Clin Endocrinol Metab 2012 Feb;26(1):47-68. doi: 10.1016/j.beem.2011.07.003. PMID: 22305452
Tuberculum sella meningioma.
Hayhurst C, Teo C
Otolaryngol Clin North Am 2011 Aug;44(4):953-63, viii-ix. doi: 10.1016/j.otc.2011.06.012. PMID: 21819882
Craniopharyngioma.
Stamm AC, Vellutini E, Balsalobre L
Otolaryngol Clin North Am 2011 Aug;44(4):937-52, viii. doi: 10.1016/j.otc.2011.06.015. PMID: 21819881

Prognosis

Imaging findings in hypophysitis: a review.
Caranci F, Leone G, Ponsiglione A, Muto M, Tortora F, Muto M, Cirillo S, Brunese L, Cerase A
Radiol Med 2020 Mar;125(3):319-328. Epub 2019 Dec 20 doi: 10.1007/s11547-019-01120-x. PMID: 31863360
Nonneuroendocrine Neoplasms of the Pituitary Region.
Kaltsas GA, Kolomodi D, Randeva H, Grossman A
J Clin Endocrinol Metab 2019 Aug 1;104(8):3108-3123. doi: 10.1210/jc.2018-01871. PMID: 30779850
Immunohistochemical Biomarkers in Pituitary Pathology.
Asa SL, Mete O
Endocr Pathol 2018 Jun;29(2):130-136. doi: 10.1007/s12022-018-9521-z. PMID: 29453601
Clinical and biochemical characteristic features of metastatic cancer to the sella turcica: an analytical review.
Al-Aridi R, El Sibai K, Fu P, Khan M, Selman WR, Arafah BM
Pituitary 2014 Dec;17(6):575-87. doi: 10.1007/s11102-013-0542-9. PMID: 24337713
Central nervous system.
Adamson DC, Rasheed BA, McLendon RE, Bigner DD
Cancer Biomark 2010;9(1-6):193-210. doi: 10.3233/CBM-2011-0177. PMID: 22112477

Clinical prediction guides

Imaging findings in hypophysitis: a review.
Caranci F, Leone G, Ponsiglione A, Muto M, Tortora F, Muto M, Cirillo S, Brunese L, Cerase A
Radiol Med 2020 Mar;125(3):319-328. Epub 2019 Dec 20 doi: 10.1007/s11547-019-01120-x. PMID: 31863360
Nonneuroendocrine Neoplasms of the Pituitary Region.
Kaltsas GA, Kolomodi D, Randeva H, Grossman A
J Clin Endocrinol Metab 2019 Aug 1;104(8):3108-3123. doi: 10.1210/jc.2018-01871. PMID: 30779850
Immunohistochemical Biomarkers in Pituitary Pathology.
Asa SL, Mete O
Endocr Pathol 2018 Jun;29(2):130-136. doi: 10.1007/s12022-018-9521-z. PMID: 29453601
Clinical and biochemical characteristic features of metastatic cancer to the sella turcica: an analytical review.
Al-Aridi R, El Sibai K, Fu P, Khan M, Selman WR, Arafah BM
Pituitary 2014 Dec;17(6):575-87. doi: 10.1007/s11102-013-0542-9. PMID: 24337713
Pilomyxoid astrocytoma.
Azad S, Kudesia S, Chawla N, Azad R, Singhal M, Rai SM, Arora P
Indian J Pathol Microbiol 2010 Apr-Jun;53(2):294-6. doi: 10.4103/0377-4929.64283. PMID: 20551536

Recent systematic reviews

Endocrinological outcomes after transcranial resection of tuberculum sellae meningiomas: a systematic review and meta-analysis.
Martinez-Perez R, Kortz MW, Florez-Perdomo W, Ung TH, Youssef AS
Neurosurg Rev 2022 Jun;45(3):1965-1975. Epub 2022 Feb 12 doi: 10.1007/s10143-022-01744-0. PMID: 35149901
Salivary gland tissues and derived primary and metastatic neoplasms: unusual pitfalls in the work-up of sellar lesions. A systematic review.
Feola T, Gianno F, De Angelis M, Colonnese C, Esposito V, Giangaspero F, Jaffrain-Rea ML
J Endocrinol Invest 2021 Oct;44(10):2103-2122. Epub 2021 May 3 doi: 10.1007/s40618-021-01577-6. PMID: 33939106Free PMC Article
Endonasal Endoscopic Surgery for Pediatric Sellar and Suprasellar Lesions: A Systematic Review and Meta-analysis.
Lee JA, Cooper RL, Nguyen SA, Schlosser RJ, Gudis DA
Otolaryngol Head Neck Surg 2020 Aug;163(2):284-292. Epub 2020 Mar 24 doi: 10.1177/0194599820913637. PMID: 32204653
Gangliocytomas of the sellar region: A challenging diagnosis.
Cossu G, Daniel RT, Messerer M
Clin Neurol Neurosurg 2016 Oct;149:122-35. Epub 2016 Aug 9 doi: 10.1016/j.clineuro.2016.08.002. PMID: 27521460
Endoscopic surgery for tuberculum sellae meningiomas: a systematic review and meta-analysis.
Clark AJ, Jahangiri A, Garcia RM, George JR, Sughrue ME, McDermott MW, El-Sayed IH, Aghi MK
Neurosurg Rev 2013 Jul;36(3):349-59. Epub 2013 Apr 9 doi: 10.1007/s10143-013-0458-x. PMID: 23568697

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