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Central Nervous System Lesion

MedGen UID:
1718544
•Concept ID:
C0742468
•
Disease or Syndrome

Definition

A localized pathological or traumatic structural change, damage, deformity, or discontinuity in the central nervous system. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral Nervous System Lesion

Professional guidelines

PubMed

Clinical and imaging clues to the diagnosis and follow-up of ptosis and ophthalmoparesis.
Keene KR, Kan HE, van der Meeren S, Verbist BM, Tannemaat MR, Beenakker JM, Verschuuren JJGM
J Cachexia Sarcopenia Muscle 2022 Dec;13(6):2820-2834. Epub 2022 Sep 29 doi: 10.1002/jcsm.13089. PMID: 36172973Free PMC Article
Implanted Peroneal Nerve Stimulator Treatment for Drop Foot Caused by Central Nervous System Lesion: A Twelve-Month Follow-up of 21 Patients.
Severinsen K, Grey K, Haase Juhl A, Soerensen P, Oppel L, Magnussen I, Tine Larsen B
J Rehabil Med 2022 Jun 20;54:jrm00288. doi: 10.2340/jrm.v54.2164. PMID: 35451494Free PMC Article
Treatment of psychogenic nonepileptic seizures: updated review and findings from a mindfulness-based intervention case series.
Baslet G, Dworetzky B, Perez DL, Oser M
Clin EEG Neurosci 2015 Jan;46(1):54-64. Epub 2014 Dec 2 doi: 10.1177/1550059414557025. PMID: 25465435Free PMC Article

Recent clinical studies

Etiology

Implanted Peroneal Nerve Stimulator Treatment for Drop Foot Caused by Central Nervous System Lesion: A Twelve-Month Follow-up of 21 Patients.
Severinsen K, Grey K, Haase Juhl A, Soerensen P, Oppel L, Magnussen I, Tine Larsen B
J Rehabil Med 2022 Jun 20;54:jrm00288. doi: 10.2340/jrm.v54.2164. PMID: 35451494Free PMC Article
Hypereosinophilic syndrome with central nervous system involvement: Two case reports and literature review.
Chen H, Raza HK, Jing J, Shen D, Xu P, Zhou S, Zu J, Yang X, Zhang W, Zhang S, Hua F, Cui G
Brain Inj 2017;31(12):1695-1700. Epub 2017 Sep 25 doi: 10.1080/02699052.2017.1357835. PMID: 28945486
The Use of Oral Disease-Modifying Therapies in Multiple Sclerosis.
Kretzschmar B, Pellkofer H, Weber MS
Curr Neurol Neurosci Rep 2016 Apr;16(4):38. doi: 10.1007/s11910-016-0639-4. PMID: 26944956
Audiometry screening and interpretation.
Walker JJ, Cleveland LM, Davis JL, Seales JS
Am Fam Physician 2013 Jan 1;87(1):41-7. PMID: 23317024
Prognostic factors in severe head injury.
Davis RA, Cunningham PS
Surg Gynecol Obstet 1984 Dec;159(6):597-604. PMID: 6390762

Diagnosis

Clinical and imaging clues to the diagnosis and follow-up of ptosis and ophthalmoparesis.
Keene KR, Kan HE, van der Meeren S, Verbist BM, Tannemaat MR, Beenakker JM, Verschuuren JJGM
J Cachexia Sarcopenia Muscle 2022 Dec;13(6):2820-2834. Epub 2022 Sep 29 doi: 10.1002/jcsm.13089. PMID: 36172973Free PMC Article
NEUROLOGICAL MANIFESTATIONS OF PROLACTINOMA (CASE REPORT).
Naumova L, Milevska-Vovchuk L, Burak A, Krytskyy T, Pankiv I
Georgian Med News 2021 May;(314):116-120. PMID: 34248039
Audiometry screening and interpretation.
Walker JJ, Cleveland LM, Davis JL, Seales JS
Am Fam Physician 2013 Jan 1;87(1):41-7. PMID: 23317024
How to clinically assess and treat muscle overactivity in spastic paresis.
Yelnik AP, Simon O, Parratte B, Gracies JM
J Rehabil Med 2010 Oct;42(9):801-7. doi: 10.2340/16501977-0613. PMID: 20878038
Prognostic factors in severe head injury.
Davis RA, Cunningham PS
Surg Gynecol Obstet 1984 Dec;159(6):597-604. PMID: 6390762

Therapy

Health-enhancing physical activity interventions in non-ambulatory people with severe motor impairments - a scoping review.
Graf ES, Perret C, Labruyère R, Möller JC, Wirz M
Ann Med 2023 Dec;55(1):2219065. doi: 10.1080/07853890.2023.2219065. PMID: 37287318Free PMC Article
The Use of Oral Disease-Modifying Therapies in Multiple Sclerosis.
Kretzschmar B, Pellkofer H, Weber MS
Curr Neurol Neurosci Rep 2016 Apr;16(4):38. doi: 10.1007/s11910-016-0639-4. PMID: 26944956
Treatment of psychogenic nonepileptic seizures: updated review and findings from a mindfulness-based intervention case series.
Baslet G, Dworetzky B, Perez DL, Oser M
Clin EEG Neurosci 2015 Jan;46(1):54-64. Epub 2014 Dec 2 doi: 10.1177/1550059414557025. PMID: 25465435Free PMC Article
Ghrelin: a novel neuromuscular recovery promoting factor?
Raimondo S, Ronchi G, Geuna S, Pascal D, Reano S, Filigheddu N, Graziani A
Int Rev Neurobiol 2013;108:207-21. doi: 10.1016/B978-0-12-410499-0.00008-3. PMID: 24083436
How to clinically assess and treat muscle overactivity in spastic paresis.
Yelnik AP, Simon O, Parratte B, Gracies JM
J Rehabil Med 2010 Oct;42(9):801-7. doi: 10.2340/16501977-0613. PMID: 20878038

Prognosis

Implanted Peroneal Nerve Stimulator Treatment for Drop Foot Caused by Central Nervous System Lesion: A Twelve-Month Follow-up of 21 Patients.
Severinsen K, Grey K, Haase Juhl A, Soerensen P, Oppel L, Magnussen I, Tine Larsen B
J Rehabil Med 2022 Jun 20;54:jrm00288. doi: 10.2340/jrm.v54.2164. PMID: 35451494Free PMC Article
NEUROLOGICAL MANIFESTATIONS OF PROLACTINOMA (CASE REPORT).
Naumova L, Milevska-Vovchuk L, Burak A, Krytskyy T, Pankiv I
Georgian Med News 2021 May;(314):116-120. PMID: 34248039
Hypereosinophilic syndrome with central nervous system involvement: Two case reports and literature review.
Chen H, Raza HK, Jing J, Shen D, Xu P, Zhou S, Zu J, Yang X, Zhang W, Zhang S, Hua F, Cui G
Brain Inj 2017;31(12):1695-1700. Epub 2017 Sep 25 doi: 10.1080/02699052.2017.1357835. PMID: 28945486
Energy requirements of children with cerebral palsy.
Hogan SE
Can J Diet Pract Res 2004 Fall;65(3):124-30. doi: 10.3148/65.3.2004.124. PMID: 15363117
Prognostic factors in severe head injury.
Davis RA, Cunningham PS
Surg Gynecol Obstet 1984 Dec;159(6):597-604. PMID: 6390762

Clinical prediction guides

Clinical and imaging clues to the diagnosis and follow-up of ptosis and ophthalmoparesis.
Keene KR, Kan HE, van der Meeren S, Verbist BM, Tannemaat MR, Beenakker JM, Verschuuren JJGM
J Cachexia Sarcopenia Muscle 2022 Dec;13(6):2820-2834. Epub 2022 Sep 29 doi: 10.1002/jcsm.13089. PMID: 36172973Free PMC Article
NEUROLOGICAL MANIFESTATIONS OF PROLACTINOMA (CASE REPORT).
Naumova L, Milevska-Vovchuk L, Burak A, Krytskyy T, Pankiv I
Georgian Med News 2021 May;(314):116-120. PMID: 34248039
Energy requirements of children with cerebral palsy.
Hogan SE
Can J Diet Pract Res 2004 Fall;65(3):124-30. doi: 10.3148/65.3.2004.124. PMID: 15363117
Central precocious puberty: clinical and laboratory features.
Chemaitilly W, Trivin C, Adan L, Gall V, Sainte-Rose C, Brauner R
Clin Endocrinol (Oxf) 2001 Mar;54(3):289-94. doi: 10.1046/j.1365-2265.2001.01229.x. PMID: 11298079
Prognostic factors in severe head injury.
Davis RA, Cunningham PS
Surg Gynecol Obstet 1984 Dec;159(6):597-604. PMID: 6390762

Recent systematic reviews

Health-enhancing physical activity interventions in non-ambulatory people with severe motor impairments - a scoping review.
Graf ES, Perret C, Labruyère R, Möller JC, Wirz M
Ann Med 2023 Dec;55(1):2219065. doi: 10.1080/07853890.2023.2219065. PMID: 37287318Free PMC Article
Deep brain stimulation for lesion-related tremors: A systematic review and meta-analysis.
Mendonça MD, Meira B, Fernandes M, Barbosa R, Bugalho P
Parkinsonism Relat Disord 2018 Feb;47:8-14. Epub 2017 Dec 13 doi: 10.1016/j.parkreldis.2017.12.014. PMID: 29249682

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