U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Disorder of macula of retina

MedGen UID:
488928
•Concept ID:
C0730362
•
Disease or Syndrome
Synonym: Maculopathy
SNOMED CT: Disorder of macula of retina (312999006); Disorder of macula lutea (312999006); Maculopathy (312999006); Macular disease (312999006); Macular disorder (312999006)

Professional guidelines

PubMed

Central serous chorioretinopathy: An evidence-based treatment guideline.
Feenstra HMA, van Dijk EHC, Cheung CMG, Ohno-Matsui K, Lai TYY, Koizumi H, Larsen M, Querques G, Downes SM, Yzer S, Breazzano MP, Subhi Y, Tadayoni R, Priglinger SG, Pauleikhoff LJB, Lange CAK, Loewenstein A, Diederen RMH, Schlingemann RO, Hoyng CB, Chhablani JK, Holz FG, Sivaprasad S, Lotery AJ, Yannuzzi LA, Freund KB, Boon CJF
Prog Retin Eye Res 2024 Jul;101:101236. Epub 2024 Feb 1 doi: 10.1016/j.preteyeres.2024.101236. PMID: 38301969
Central serous chorioretinopathy: Towards an evidence-based treatment guideline.
van Rijssen TJ, van Dijk EHC, Yzer S, Ohno-Matsui K, Keunen JEE, Schlingemann RO, Sivaprasad S, Querques G, Downes SM, Fauser S, Hoyng CB, Piccolino FC, Chhablani JK, Lai TYY, Lotery AJ, Larsen M, Holz FG, Freund KB, Yannuzzi LA, Boon CJF
Prog Retin Eye Res 2019 Nov;73:100770. Epub 2019 Jul 15 doi: 10.1016/j.preteyeres.2019.07.003. PMID: 31319157
Guidelines for the management of neovascular age-related macular degeneration by the European Society of Retina Specialists (EURETINA).
Schmidt-Erfurth U, Chong V, Loewenstein A, Larsen M, Souied E, Schlingemann R, Eldem B, Monés J, Richard G, Bandello F; European Society of Retina Specialists
Br J Ophthalmol 2014 Sep;98(9):1144-67. doi: 10.1136/bjophthalmol-2014-305702. PMID: 25136079Free PMC Article

Recent clinical studies

Etiology

Myopic macular diseases: A review.
Ng DSC, Chan LKY, Lai TYY
Clin Exp Ophthalmol 2023 Apr;51(3):229-242. Epub 2023 Jan 11 doi: 10.1111/ceo.14200. PMID: 36594934
Therapeutic Approaches for Age-Related Macular Degeneration.
Galindo-Camacho RM, Blanco-Llamero C, da Ana R, Fuertes MA, Señoráns FJ, Silva AM, García ML, Souto EB
Int J Mol Sci 2022 Oct 4;23(19) doi: 10.3390/ijms231911769. PMID: 36233066Free PMC Article
PERIPAPILLARY PACHYCHOROID SYNDROME.
Phasukkijwatana N, Freund KB, Dolz-Marco R, Al-Sheikh M, Keane PA, Egan CA, Randhawa S, Stewart JM, Liu Q, Hunyor AP, Kreiger A, Nagiel A, Lalane R, Rahimi M, Lee WK, Jampol LM, Sarraf D
Retina 2018 Sep;38(9):1652-1667. doi: 10.1097/IAE.0000000000001907. PMID: 29135799
Acute macular neuroretinopathy: A comprehensive review of the literature.
Bhavsar KV, Lin S, Rahimy E, Joseph A, Freund KB, Sarraf D, Cunningham ET Jr
Surv Ophthalmol 2016 Sep-Oct;61(5):538-65. Epub 2016 Mar 10 doi: 10.1016/j.survophthal.2016.03.003. PMID: 26973287
Diabetic retinopathy.
Neely KA, Quillen DA, Schachat AP, Gardner TW, Blankenship GW
Med Clin North Am 1998 Jul;82(4):847-76. doi: 10.1016/s0025-7125(05)70027-4. PMID: 9706124

Diagnosis

Myopic macular diseases: A review.
Ng DSC, Chan LKY, Lai TYY
Clin Exp Ophthalmol 2023 Apr;51(3):229-242. Epub 2023 Jan 11 doi: 10.1111/ceo.14200. PMID: 36594934
Juvenile Macular Degenerations.
Altschwager P, Ambrosio L, Swanson EA, Moskowitz A, Fulton AB
Semin Pediatr Neurol 2017 May;24(2):104-109. Epub 2017 May 23 doi: 10.1016/j.spen.2017.05.005. PMID: 28941524Free PMC Article
Acute macular neuroretinopathy: A comprehensive review of the literature.
Bhavsar KV, Lin S, Rahimy E, Joseph A, Freund KB, Sarraf D, Cunningham ET Jr
Surv Ophthalmol 2016 Sep-Oct;61(5):538-65. Epub 2016 Mar 10 doi: 10.1016/j.survophthal.2016.03.003. PMID: 26973287
Famous.
Kim MJ, Bhatti MT, Costello F
Surv Ophthalmol 2016 Jul-Aug;61(4):512-9. Epub 2015 Dec 29 doi: 10.1016/j.survophthal.2015.12.008. PMID: 26742785
Diabetic macular edema.
Cunha-Vaz J
Eur J Ophthalmol 1998 Jul-Sep;8(3):127-30. doi: 10.1177/112067219800800301. PMID: 9793763

Therapy

Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials.
Wykoff CC, Abreu F, Adamis AP, Basu K, Eichenbaum DA, Haskova Z, Lin H, Loewenstein A, Mohan S, Pearce IA, Sakamoto T, Schlottmann PG, Silverman D, Sun JK, Wells JA, Willis JR, Tadayoni R; YOSEMITE and RHINE Investigators
Lancet 2022 Feb 19;399(10326):741-755. Epub 2022 Jan 24 doi: 10.1016/S0140-6736(22)00018-6. PMID: 35085503
Lutein Supplementation for Eye Diseases.
Li LH, Lee JC, Leung HH, Lam WC, Fu Z, Lo ACY
Nutrients 2020 Jun 9;12(6) doi: 10.3390/nu12061721. PMID: 32526861Free PMC Article
The effect of blue-light blocking spectacle lenses on visual performance, macular health and the sleep-wake cycle: a systematic review of the literature.
Lawrenson JG, Hull CC, Downie LE
Ophthalmic Physiol Opt 2017 Nov;37(6):644-654. doi: 10.1111/opo.12406. PMID: 29044670
Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease.
Bernstein PS, Li B, Vachali PP, Gorusupudi A, Shyam R, Henriksen BS, Nolan JM
Prog Retin Eye Res 2016 Jan;50:34-66. Epub 2015 Nov 2 doi: 10.1016/j.preteyeres.2015.10.003. PMID: 26541886Free PMC Article
Cystoid maculopathy.
Irvine AR
Surv Ophthalmol 1976 Jul-Aug;21(1):1-17. doi: 10.1016/0039-6257(76)90045-x. PMID: 785652

Prognosis

Myopic macular diseases: A review.
Ng DSC, Chan LKY, Lai TYY
Clin Exp Ophthalmol 2023 Apr;51(3):229-242. Epub 2023 Jan 11 doi: 10.1111/ceo.14200. PMID: 36594934
Risk factors for progression of age-related macular degeneration.
Heesterbeek TJ, Lorés-Motta L, Hoyng CB, Lechanteur YTE, den Hollander AI
Ophthalmic Physiol Opt 2020 Mar;40(2):140-170. Epub 2020 Feb 25 doi: 10.1111/opo.12675. PMID: 32100327Free PMC Article
PERIPAPILLARY PACHYCHOROID SYNDROME.
Phasukkijwatana N, Freund KB, Dolz-Marco R, Al-Sheikh M, Keane PA, Egan CA, Randhawa S, Stewart JM, Liu Q, Hunyor AP, Kreiger A, Nagiel A, Lalane R, Rahimi M, Lee WK, Jampol LM, Sarraf D
Retina 2018 Sep;38(9):1652-1667. doi: 10.1097/IAE.0000000000001907. PMID: 29135799
Coats'-type retinitis pigmentosa.
Khan JA, Ide CH, Strickland MP
Surv Ophthalmol 1988 Mar-Apr;32(5):317-32. doi: 10.1016/0039-6257(88)90094-x. PMID: 2457260
Cystoid maculopathy.
Irvine AR
Surv Ophthalmol 1976 Jul-Aug;21(1):1-17. doi: 10.1016/0039-6257(76)90045-x. PMID: 785652

Clinical prediction guides

Maculopathies in Glaucoma.
Teuchner B, Rauchegger T
Klin Monbl Augenheilkd 2022 Sep;239(9):1101-1110. Epub 2022 Sep 6 doi: 10.1055/a-1904-8248. PMID: 36067756
Risk factors for progression of age-related macular degeneration.
Heesterbeek TJ, Lorés-Motta L, Hoyng CB, Lechanteur YTE, den Hollander AI
Ophthalmic Physiol Opt 2020 Mar;40(2):140-170. Epub 2020 Feb 25 doi: 10.1111/opo.12675. PMID: 32100327Free PMC Article
Why the macula?
Bird AC, Bok D
Eye (Lond) 2018 May;32(5):858-862. Epub 2017 Nov 17 doi: 10.1038/eye.2017.247. PMID: 29148528Free PMC Article
The effect of blue-light blocking spectacle lenses on visual performance, macular health and the sleep-wake cycle: a systematic review of the literature.
Lawrenson JG, Hull CC, Downie LE
Ophthalmic Physiol Opt 2017 Nov;37(6):644-654. doi: 10.1111/opo.12406. PMID: 29044670
Diabetic macular edema.
Cunha-Vaz J
Eur J Ophthalmol 1998 Jul-Sep;8(3):127-30. doi: 10.1177/112067219800800301. PMID: 9793763

Recent systematic reviews

Retina as a potential biomarker in schizophrenia spectrum disorders: a systematic review and meta-analysis of optical coherence tomography and electroretinography.
Komatsu H, Onoguchi G, Silverstein SM, Jerotic S, Sakuma A, Kanahara N, Kakuto Y, Ono T, Yabana T, Nakazawa T, Tomita H
Mol Psychiatry 2024 Feb;29(2):464-482. Epub 2023 Dec 11 doi: 10.1038/s41380-023-02340-4. PMID: 38081943Free PMC Article
A Systematic Review of Carotenoids in the Management of Diabetic Retinopathy.
Lem DW, Gierhart DL, Davey PG
Nutrients 2021 Jul 16;13(7) doi: 10.3390/nu13072441. PMID: 34371951Free PMC Article
Prevalence and incidence of age-related macular degeneration in Europe: a systematic review and meta-analysis.
Li JQ, Welchowski T, Schmid M, Mauschitz MM, Holz FG, Finger RP
Br J Ophthalmol 2020 Aug;104(8):1077-1084. Epub 2019 Nov 11 doi: 10.1136/bjophthalmol-2019-314422. PMID: 31712255
The effect of blue-light blocking spectacle lenses on visual performance, macular health and the sleep-wake cycle: a systematic review of the literature.
Lawrenson JG, Hull CC, Downie LE
Ophthalmic Physiol Opt 2017 Nov;37(6):644-654. doi: 10.1111/opo.12406. PMID: 29044670
Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis.
Petzold A, Balcer LJ, Calabresi PA, Costello F, Frohman TC, Frohman EM, Martinez-Lapiscina EH, Green AJ, Kardon R, Outteryck O, Paul F, Schippling S, Vermersch P, Villoslada P, Balk LJ; ERN-EYE IMSVISUAL
Lancet Neurol 2017 Oct;16(10):797-812. Epub 2017 Sep 12 doi: 10.1016/S1474-4422(17)30278-8. PMID: 28920886

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...