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Genital infection

MedGen UID:
675851
•Concept ID:
C0729552
•
Disease or Syndrome
Synonym: Infectious disease of genitopelvic system
SNOMED CT: Infectious disease of genitopelvic system (312155003); Genital infection (312155003)

Professional guidelines

PubMed

Neonatal herpes simplex virus infection: epidemiology and treatment.
James SH, Kimberlin DW
Clin Perinatol 2015 Mar;42(1):47-59, viii. Epub 2014 Dec 4 doi: 10.1016/j.clp.2014.10.005. PMID: 25677996
Treatment of chlamydial infections.
Hammerschlag MR, Kohlhoff SA
Expert Opin Pharmacother 2012 Mar;13(4):545-52. Epub 2012 Feb 9 doi: 10.1517/14656566.2012.658776. PMID: 22316336
Chancroid: clinical manifestations, diagnosis, and management.
Lewis DA
Sex Transm Infect 2003 Feb;79(1):68-71. doi: 10.1136/sti.79.1.68. PMID: 12576620Free PMC Article

Recent clinical studies

Etiology

Comparison Of Efficacy And Safety Profile Of Empagliflozin Versus Dapagliflozin As Add On Therapy In Type 2 Diabetic Patients.
Hussain M, Atif M, Babar M, Akhtar L
J Ayub Med Coll Abbottabad 2021 Oct-Dec;33(4):593-597. PMID: 35124914
Safety of four SGLT2 inhibitors in three chronic diseases: A meta-analysis of large randomized trials of SGLT2 inhibitors.
Qiu M, Ding LL, Zhang M, Zhou HR
Diab Vasc Dis Res 2021 Mar-Apr;18(2):14791641211011016. doi: 10.1177/14791641211011016. PMID: 33887983Free PMC Article
Herpes simplex virus: global infection prevalence and incidence estimates, 2016.
James C, Harfouche M, Welton NJ, Turner KM, Abu-Raddad LJ, Gottlieb SL, Looker KJ
Bull World Health Organ 2020 May 1;98(5):315-329. Epub 2020 Mar 25 doi: 10.2471/BLT.19.237149. PMID: 32514197Free PMC Article
Efficacy and safety of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes mellitus: systematic review and network meta-analysis.
Zaccardi F, Webb DR, Htike ZZ, Youssef D, Khunti K, Davies MJ
Diabetes Obes Metab 2016 Aug;18(8):783-94. Epub 2016 May 13 doi: 10.1111/dom.12670. PMID: 27059700
Probiotics.
Gupta V, Garg R
Indian J Med Microbiol 2009 Jul-Sep;27(3):202-9. doi: 10.4103/0255-0857.53201. PMID: 19584499

Diagnosis

Comparative Effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors for Recurrent Gout Flares and Gout-Primary Emergency Department Visits and Hospitalizations : A General Population Cohort Study.
McCormick N, Yokose C, Wei J, Lu N, Wexler DJ, Aviña-Zubieta JA, De Vera MA, Zhang Y, Choi HK
Ann Intern Med 2023 Aug;176(8):1067-1080. Epub 2023 Jul 25 doi: 10.7326/M23-0724. PMID: 37487215
Safety outcomes of SGLT2i in the heart failure trials: A systematic review and Meta-analysis.
Younes AM, Salem M, Maraey A, Nomigolzar S, Sewell K, Khalil M, Elzanaty A, Saeyeldin A, Dar M
Int J Cardiol 2022 Nov 1;366:51-56. Epub 2022 Jun 29 doi: 10.1016/j.ijcard.2022.06.059. PMID: 35777490
Sodium-Glucose Cotransporter-2 Inhibitors in Patients With Heart Failure : A Systematic Review and Meta-analysis.
Zou X, Shi Q, Vandvik PO, Guyatt G, Lang CC, Parpia S, Wang S, Agarwal A, Zhou Y, Zhu Y, Tian H, Zhu Z, Li S
Ann Intern Med 2022 Jun;175(6):851-861. Epub 2022 Apr 12 doi: 10.7326/M21-4284. PMID: 35404670
Safety of four SGLT2 inhibitors in three chronic diseases: A meta-analysis of large randomized trials of SGLT2 inhibitors.
Qiu M, Ding LL, Zhang M, Zhou HR
Diab Vasc Dis Res 2021 Mar-Apr;18(2):14791641211011016. doi: 10.1177/14791641211011016. PMID: 33887983Free PMC Article
Herpes simplex virus: global infection prevalence and incidence estimates, 2016.
James C, Harfouche M, Welton NJ, Turner KM, Abu-Raddad LJ, Gottlieb SL, Looker KJ
Bull World Health Organ 2020 May 1;98(5):315-329. Epub 2020 Mar 25 doi: 10.2471/BLT.19.237149. PMID: 32514197Free PMC Article

Therapy

Global and regional estimates of genital human papillomavirus prevalence among men: a systematic review and meta-analysis.
Bruni L, Albero G, Rowley J, Alemany L, Arbyn M, Giuliano AR, Markowitz LE, Broutet N, Taylor M
Lancet Glob Health 2023 Sep;11(9):e1345-e1362. doi: 10.1016/S2214-109X(23)00305-4. PMID: 37591583Free PMC Article
Safety of four SGLT2 inhibitors in three chronic diseases: A meta-analysis of large randomized trials of SGLT2 inhibitors.
Qiu M, Ding LL, Zhang M, Zhou HR
Diab Vasc Dis Res 2021 Mar-Apr;18(2):14791641211011016. doi: 10.1177/14791641211011016. PMID: 33887983Free PMC Article
Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials.
Palmer SC, Tendal B, Mustafa RA, Vandvik PO, Li S, Hao Q, Tunnicliffe D, Ruospo M, Natale P, Saglimbene V, Nicolucci A, Johnson DW, Tonelli M, Rossi MC, Badve SV, Cho Y, Nadeau-Fredette AC, Burke M, Faruque LI, Lloyd A, Ahmad N, Liu Y, Tiv S, Millard T, Gagliardi L, Kolanu N, Barmanray RD, McMorrow R, Raygoza Cortez AK, White H, Chen X, Zhou X, Liu J, Rodríguez AF, González-Colmenero AD, Wang Y, Li L, Sutanto S, Solis RC, Díaz González-Colmenero F, Rodriguez-Gutierrez R, Walsh M, Guyatt G, Strippoli GFM
BMJ 2021 Jan 13;372:m4573. doi: 10.1136/bmj.m4573. PMID: 33441402Free PMC Article
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE; EMPA-REG OUTCOME Investigators
N Engl J Med 2015 Nov 26;373(22):2117-28. Epub 2015 Sep 17 doi: 10.1056/NEJMoa1504720. PMID: 26378978
Probiotics.
Gupta V, Garg R
Indian J Med Microbiol 2009 Jul-Sep;27(3):202-9. doi: 10.4103/0255-0857.53201. PMID: 19584499

Prognosis

Safety outcomes of SGLT2i in the heart failure trials: A systematic review and Meta-analysis.
Younes AM, Salem M, Maraey A, Nomigolzar S, Sewell K, Khalil M, Elzanaty A, Saeyeldin A, Dar M
Int J Cardiol 2022 Nov 1;366:51-56. Epub 2022 Jun 29 doi: 10.1016/j.ijcard.2022.06.059. PMID: 35777490
Sodium-Glucose Cotransporter-2 Inhibitors in Patients With Heart Failure : A Systematic Review and Meta-analysis.
Zou X, Shi Q, Vandvik PO, Guyatt G, Lang CC, Parpia S, Wang S, Agarwal A, Zhou Y, Zhu Y, Tian H, Zhu Z, Li S
Ann Intern Med 2022 Jun;175(6):851-861. Epub 2022 Apr 12 doi: 10.7326/M21-4284. PMID: 35404670
Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials.
Palmer SC, Tendal B, Mustafa RA, Vandvik PO, Li S, Hao Q, Tunnicliffe D, Ruospo M, Natale P, Saglimbene V, Nicolucci A, Johnson DW, Tonelli M, Rossi MC, Badve SV, Cho Y, Nadeau-Fredette AC, Burke M, Faruque LI, Lloyd A, Ahmad N, Liu Y, Tiv S, Millard T, Gagliardi L, Kolanu N, Barmanray RD, McMorrow R, Raygoza Cortez AK, White H, Chen X, Zhou X, Liu J, Rodríguez AF, González-Colmenero AD, Wang Y, Li L, Sutanto S, Solis RC, Díaz González-Colmenero F, Rodriguez-Gutierrez R, Walsh M, Guyatt G, Strippoli GFM
BMJ 2021 Jan 13;372:m4573. doi: 10.1136/bmj.m4573. PMID: 33441402Free PMC Article
Herpes simplex virus: global infection prevalence and incidence estimates, 2016.
James C, Harfouche M, Welton NJ, Turner KM, Abu-Raddad LJ, Gottlieb SL, Looker KJ
Bull World Health Organ 2020 May 1;98(5):315-329. Epub 2020 Mar 25 doi: 10.2471/BLT.19.237149. PMID: 32514197Free PMC Article
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE; EMPA-REG OUTCOME Investigators
N Engl J Med 2015 Nov 26;373(22):2117-28. Epub 2015 Sep 17 doi: 10.1056/NEJMoa1504720. PMID: 26378978

Clinical prediction guides

Comparison Of Efficacy And Safety Profile Of Empagliflozin Versus Dapagliflozin As Add On Therapy In Type 2 Diabetic Patients.
Hussain M, Atif M, Babar M, Akhtar L
J Ayub Med Coll Abbottabad 2021 Oct-Dec;33(4):593-597. PMID: 35124914
Empagliflozin and Cardiovascular and Kidney Outcomes across KDIGO Risk Categories: Post Hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Multinational Trial.
Levin A, Perkovic V, Wheeler DC, Hantel S, George JT, von Eynatten M, Koitka-Weber A, Wanner C; EMPA-REG OUTCOME Investigators
Clin J Am Soc Nephrol 2020 Oct 7;15(10):1433-1444. Epub 2020 Sep 29 doi: 10.2215/CJN.14901219. PMID: 32994159Free PMC Article
Herpes simplex virus: global infection prevalence and incidence estimates, 2016.
James C, Harfouche M, Welton NJ, Turner KM, Abu-Raddad LJ, Gottlieb SL, Looker KJ
Bull World Health Organ 2020 May 1;98(5):315-329. Epub 2020 Mar 25 doi: 10.2471/BLT.19.237149. PMID: 32514197Free PMC Article
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
Zinman B, Wanner C, Lachin JM, Fitchett D, Bluhmki E, Hantel S, Mattheus M, Devins T, Johansen OE, Woerle HJ, Broedl UC, Inzucchi SE; EMPA-REG OUTCOME Investigators
N Engl J Med 2015 Nov 26;373(22):2117-28. Epub 2015 Sep 17 doi: 10.1056/NEJMoa1504720. PMID: 26378978
Dapagliflozin is effective as add-on therapy to sitagliptin with or without metformin: a 24-week, multicenter, randomized, double-blind, placebo-controlled study.
Jabbour SA, Hardy E, Sugg J, Parikh S; Study 10 Group
Diabetes Care 2014;37(3):740-50. Epub 2013 Oct 21 doi: 10.2337/dc13-0467. PMID: 24144654

Recent systematic reviews

Global and regional estimates of genital human papillomavirus prevalence among men: a systematic review and meta-analysis.
Bruni L, Albero G, Rowley J, Alemany L, Arbyn M, Giuliano AR, Markowitz LE, Broutet N, Taylor M
Lancet Glob Health 2023 Sep;11(9):e1345-e1362. doi: 10.1016/S2214-109X(23)00305-4. PMID: 37591583Free PMC Article
SGLT2 inhibitors in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials balancing their risks and benefits.
Marilly E, Cottin J, Cabrera N, Cornu C, Boussageon R, Moulin P, Lega JC, Gueyffier F, Cucherat M, Grenet G
Diabetologia 2022 Dec;65(12):2000-2010. Epub 2022 Aug 4 doi: 10.1007/s00125-022-05773-8. PMID: 35925319
Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials.
Palmer SC, Tendal B, Mustafa RA, Vandvik PO, Li S, Hao Q, Tunnicliffe D, Ruospo M, Natale P, Saglimbene V, Nicolucci A, Johnson DW, Tonelli M, Rossi MC, Badve SV, Cho Y, Nadeau-Fredette AC, Burke M, Faruque LI, Lloyd A, Ahmad N, Liu Y, Tiv S, Millard T, Gagliardi L, Kolanu N, Barmanray RD, McMorrow R, Raygoza Cortez AK, White H, Chen X, Zhou X, Liu J, Rodríguez AF, González-Colmenero AD, Wang Y, Li L, Sutanto S, Solis RC, Díaz González-Colmenero F, Rodriguez-Gutierrez R, Walsh M, Guyatt G, Strippoli GFM
BMJ 2021 Jan 13;372:m4573. doi: 10.1136/bmj.m4573. PMID: 33441402Free PMC Article
Herpes simplex virus: global infection prevalence and incidence estimates, 2016.
James C, Harfouche M, Welton NJ, Turner KM, Abu-Raddad LJ, Gottlieb SL, Looker KJ
Bull World Health Organ 2020 May 1;98(5):315-329. Epub 2020 Mar 25 doi: 10.2471/BLT.19.237149. PMID: 32514197Free PMC Article
Efficacy and safety of sodium-glucose co-transporter-2 inhibitors in type 2 diabetes mellitus: systematic review and network meta-analysis.
Zaccardi F, Webb DR, Htike ZZ, Youssef D, Khunti K, Davies MJ
Diabetes Obes Metab 2016 Aug;18(8):783-94. Epub 2016 May 13 doi: 10.1111/dom.12670. PMID: 27059700

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