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Community acquired pneumonia

MedGen UID:
675054
Concept ID:
C0694549
Disease or Syndrome
Synonym: Community-acquired pneumonia
SNOMED CT: Community acquired pneumonia (385093006); CAP - community acquired pneumonia (385093006)

Definition

Pneumonia that is not acquired in a hospital or long-term care facility setting. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCommunity acquired pneumonia

Professional guidelines

PubMed

Martin-Loeches I, Torres A, Nagavci B, Aliberti S, Antonelli M, Bassetti M, Bos LD, Chalmers JD, Derde L, de Waele J, Garnacho-Montero J, Kollef M, Luna CM, Menendez R, Niederman MS, Ponomarev D, Restrepo MI, Rigau D, Schultz MJ, Weiss E, Welte T, Wunderink R
Intensive Care Med 2023 Jun;49(6):615-632. Epub 2023 Apr 4 doi: 10.1007/s00134-023-07033-8. PMID: 37012484Free PMC Article
Miyashita N
Respir Investig 2022 Jan;60(1):56-67. Epub 2021 Nov 5 doi: 10.1016/j.resinv.2021.09.009. PMID: 34750083
Metlay JP, Waterer GW, Long AC, Anzueto A, Brozek J, Crothers K, Cooley LA, Dean NC, Fine MJ, Flanders SA, Griffin MR, Metersky ML, Musher DM, Restrepo MI, Whitney CG
Am J Respir Crit Care Med 2019 Oct 1;200(7):e45-e67. doi: 10.1164/rccm.201908-1581ST. PMID: 31573350Free PMC Article

Recent clinical studies

Etiology

Aliberti S, Dela Cruz CS, Amati F, Sotgiu G, Restrepo MI
Lancet 2021 Sep 4;398(10303):906-919. doi: 10.1016/S0140-6736(21)00630-9. PMID: 34481570
Nair GB, Niederman MS
Pharmacol Ther 2021 Jan;217:107663. Epub 2020 Aug 15 doi: 10.1016/j.pharmthera.2020.107663. PMID: 32805298Free PMC Article
Modi AR, Kovacs CS
Cleve Clin J Med 2020 Mar;87(3):145-151. doi: 10.3949/ccjm.87a.19067. PMID: 32127438
Rider AC, Frazee BW
Emerg Med Clin North Am 2018 Nov;36(4):665-683. Epub 2018 Sep 6 doi: 10.1016/j.emc.2018.07.001. PMID: 30296998Free PMC Article
Leung AKC, Wong AHC, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2018;12(2):136-144. doi: 10.2174/1872213X12666180621163821. PMID: 29932038

Diagnosis

Niederman MS, Torres A
Eur Respir Rev 2022 Dec 31;31(166) Epub 2022 Dec 14 doi: 10.1183/16000617.0123-2022. PMID: 36517046Free PMC Article
Rothberg MB
Ann Intern Med 2022 Apr;175(4):ITC49-ITC64. Epub 2022 Apr 12 doi: 10.7326/AITC202204190. PMID: 35404672
Smith DK, Kuckel DP, Recidoro AM
Am Fam Physician 2021 Dec 1;104(6):618-625. PMID: 34913645
Aliberti S, Dela Cruz CS, Amati F, Sotgiu G, Restrepo MI
Lancet 2021 Sep 4;398(10303):906-919. doi: 10.1016/S0140-6736(21)00630-9. PMID: 34481570
Leung AKC, Wong AHC, Hon KL
Recent Pat Inflamm Allergy Drug Discov 2018;12(2):136-144. doi: 10.2174/1872213X12666180621163821. PMID: 29932038

Therapy

Giamarellos-Bourboulis EJ, Siampanos A, Bolanou A, Doulou S, Kakavoulis N, Tsiakos K, Katopodis S, Schinas G, Skorda L, Alexiou Z, Armenis K, Katsaounou P, Chrysos G, Masgala A, Poulakou G, Antonakos N, Safarika A, Kyprianou M, Dakou K, Gerakari S, Papanikolaou IC, Milionis H, Marangos M, Dalekos GN, Tzavara V, Akinosoglou K, Hatziaggelaki E, Sympardi S, Kontopoulou T, Mouktaroudi M, Papadopoulos A, Niederman MS
Lancet Respir Med 2024 Apr;12(4):294-304. Epub 2024 Jan 3 doi: 10.1016/S2213-2600(23)00412-5. PMID: 38184008
Li Q, Zhou Q, Florez ID, Mathew JL, Shang L, Zhang G, Tian X, Fu Z, Liu E, Luo Z, Chen Y
JAMA Pediatr 2022 Dec 1;176(12):1199-1207. doi: 10.1001/jamapediatrics.2022.4123. PMID: 36374480Free PMC Article
Meduri GU, Shih MC, Bridges L, Martin TJ, El-Solh A, Seam N, Davis-Karim A, Umberger R, Anzueto A, Sriram P, Lan C, Restrepo MI, Guardiola JJ, Buck T, Johnson DP, Suffredini A, Bell WA, Lin J, Zhao L, Uyeda L, Nielsen L, Huang GD; ESCAPe Study Group
Intensive Care Med 2022 Aug;48(8):1009-1023. Epub 2022 May 13 doi: 10.1007/s00134-022-06684-3. PMID: 35723686Free PMC Article
Korang SK, Nava C, Mohana SP, Nygaard U, Jakobsen JC
Cochrane Database Syst Rev 2021 Nov 2;11(11):CD013864. doi: 10.1002/14651858.CD013864.pub2. PMID: 34727368Free PMC Article
Stern A, Skalsky K, Avni T, Carrara E, Leibovici L, Paul M
Cochrane Database Syst Rev 2017 Dec 13;12(12):CD007720. doi: 10.1002/14651858.CD007720.pub3. PMID: 29236286Free PMC Article

Prognosis

Cilloniz C, Ward L, Mogensen ML, Pericàs JM, Méndez R, Gabarrús A, Ferrer M, Garcia-Vidal C, Menendez R, Torres A
Chest 2023 Jan;163(1):77-88. Epub 2022 Jul 16 doi: 10.1016/j.chest.2022.07.005. PMID: 35850287
Sun Y, Li H, Pei Z, Wang S, Feng J, Xu L, Gao P, Cao B, Zhan S
Vaccine 2020 Dec 14;38(52):8362-8370. Epub 2020 Nov 13 doi: 10.1016/j.vaccine.2020.11.004. PMID: 33199077
Drijkoningen JJ, Rohde GG
Clin Microbiol Infect 2014 May;20 Suppl 5:45-51. Epub 2014 Jan 24 doi: 10.1111/1469-0691.12461. PMID: 24313448
Marti C, Garin N, Grosgurin O, Poncet A, Combescure C, Carballo S, Perrier A
Crit Care 2012 Jul 27;16(4):R141. doi: 10.1186/cc11447. PMID: 22839689Free PMC Article
Confalonieri M, Urbino R, Potena A, Piattella M, Parigi P, Puccio G, Della Porta R, Giorgio C, Blasi F, Umberger R, Meduri GU
Am J Respir Crit Care Med 2005 Feb 1;171(3):242-8. Epub 2004 Nov 19 doi: 10.1164/rccm.200406-808OC. PMID: 15557131

Clinical prediction guides

Cilloniz C, Ward L, Mogensen ML, Pericàs JM, Méndez R, Gabarrús A, Ferrer M, Garcia-Vidal C, Menendez R, Torres A
Chest 2023 Jan;163(1):77-88. Epub 2022 Jul 16 doi: 10.1016/j.chest.2022.07.005. PMID: 35850287
Shirata M, Ito I, Ishida T, Tachibana H, Tanabe N, Konishi S, Oi I, Hamao N, Nishioka K, Matsumoto H, Yasutomo Y, Kadowaki S, Ohnishi H, Tomioka H, Nishimura T, Hasegawa Y, Nakagawa A, Hirai T
Sci Rep 2021 Dec 13;11(1):23878. doi: 10.1038/s41598-021-03440-3. PMID: 34903833Free PMC Article
Torres A, Chalmers JD, Dela Cruz CS, Dominedò C, Kollef M, Martin-Loeches I, Niederman M, Wunderink RG
Intensive Care Med 2019 Feb;45(2):159-171. Epub 2019 Jan 31 doi: 10.1007/s00134-019-05519-y. PMID: 30706119Free PMC Article
Sligl WI, Marrie TJ
Crit Care Clin 2013 Jul;29(3):563-601. doi: 10.1016/j.ccc.2013.03.009. PMID: 23830654Free PMC Article
Marti C, Garin N, Grosgurin O, Poncet A, Combescure C, Carballo S, Perrier A
Crit Care 2012 Jul 27;16(4):R141. doi: 10.1186/cc11447. PMID: 22839689Free PMC Article

Recent systematic reviews

Yoshimatsu Y, Melgaard D, Westergren A, Skrubbeltrang C, Smithard DG
Eur Geriatr Med 2022 Oct;13(5):1071-1080. Epub 2022 Aug 25 doi: 10.1007/s41999-022-00689-3. PMID: 36008745Free PMC Article
Chee E, Huang K, Haggie S, Britton PN
Paediatr Respir Rev 2022 Jun;42:59-68. Epub 2022 Feb 4 doi: 10.1016/j.prrv.2022.01.006. PMID: 35210170
Chen YC, Hsu WY, Chang TH
Emerg Infect Dis 2020 Jul;26(7):1382-1391. doi: 10.3201/eid2607.200017. PMID: 32568052Free PMC Article
Stern A, Skalsky K, Avni T, Carrara E, Leibovici L, Paul M
Cochrane Database Syst Rev 2017 Dec 13;12(12):CD007720. doi: 10.1002/14651858.CD007720.pub3. PMID: 29236286Free PMC Article
Almirall J, Serra-Prat M, Bolíbar I, Balasso V
Respiration 2017;94(3):299-311. Epub 2017 Jul 25 doi: 10.1159/000479089. PMID: 28738364

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