U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Chorangioma

MedGen UID:
195606
•Concept ID:
C0677608
•
Neoplastic Process
Synonyms: Chorangiomas; Chorioangioma; Chorioangiomas
SNOMED CT: Chorangioma (699948001); Chorioangioma (699948001); Chorangioma (237268002); Chorioangioma (237268002)
 
HPO: HP:0100883
Monarch Initiative: MONDO:0006375

Definition

Hamartoma-like growth in the placenta consisting of blood vessels. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChorangioma

Professional guidelines

PubMed

Placental Pathology in Beckwith-Wiedemann Syndrome According to Genotype/Epigenotype Subgroups.
Gaillot-Durand L, Brioude F, Beneteau C, Le Breton F, Massardier J, Michon L, Devouassoux-Shisheboran M, Allias F
Fetal Pediatr Pathol 2018 Dec;37(6):387-399. Epub 2019 Jan 11 doi: 10.1080/15513815.2018.1504842. PMID: 30633605

Recent clinical studies

Etiology

Whole exome sequencing of placental chorangioma.
Mendoza RP, Doytcheva K, Ud Dean M, Jorgenson KM, Choi D, Segal J, Wang P, Lastra RR
Placenta 2024 Apr;149:13-17. Epub 2024 Mar 8 doi: 10.1016/j.placenta.2024.03.003. PMID: 38484495
The singular case of multiple chorangioma syndrome in an IVF pregnancy. Analysis of the case and review of literature.
Carlucci S, Stabile G, Sorrentino F, Nappi L, Botta G, Menato G, Masturzo B
Placenta 2021 Jan 1;103:120-123. Epub 2020 Oct 22 doi: 10.1016/j.placenta.2020.10.025. PMID: 33120047
An epidemiological study investigating the relationship between chorangioma and infantile hemangioma.
Selmin A, Foltran F, Chiarelli S, Ciullo R, Gregori D
Pathol Res Pract 2014 Sep;210(9):548-53. Epub 2014 Apr 23 doi: 10.1016/j.prp.2014.04.007. PMID: 24836731
Multifocal chorangiomatosis.
Bagby C, Redline RW
Pediatr Dev Pathol 2011 Jan-Feb;14(1):38-44. Epub 2010 Jun 28 doi: 10.2350/10-05-0832-OA.1. PMID: 20583896
Fetal hydrops associated with tumors.
Isaacs H Jr
Am J Perinatol 2008 Jan;25(1):43-68. Epub 2007 Dec 12 doi: 10.1055/s-2007-1004826. PMID: 18075961

Diagnosis

Mixed chorangioma and leiomyoma of the placenta, with a brief review of nontrophoblastic placental lesions.
Webb SD, Bonasoni MP, Palicelli A, Comitini G, Heller DS
Pediatr Dev Pathol 2022 May-Jun;25(3):316-320. Epub 2021 Oct 4 doi: 10.1177/10935266211047775. PMID: 34606386
The singular case of multiple chorangioma syndrome in an IVF pregnancy. Analysis of the case and review of literature.
Carlucci S, Stabile G, Sorrentino F, Nappi L, Botta G, Menato G, Masturzo B
Placenta 2021 Jan 1;103:120-123. Epub 2020 Oct 22 doi: 10.1016/j.placenta.2020.10.025. PMID: 33120047
An epidemiological study investigating the relationship between chorangioma and infantile hemangioma.
Selmin A, Foltran F, Chiarelli S, Ciullo R, Gregori D
Pathol Res Pract 2014 Sep;210(9):548-53. Epub 2014 Apr 23 doi: 10.1016/j.prp.2014.04.007. PMID: 24836731
Chorangioma and related vascular lesions of the placenta--a review.
Amer HZ, Heller DS
Fetal Pediatr Pathol 2010;29(4):199-206. doi: 10.3109/15513815.2010.487009. PMID: 20594143
Fetal hydrops associated with tumors.
Isaacs H Jr
Am J Perinatol 2008 Jan;25(1):43-68. Epub 2007 Dec 12 doi: 10.1055/s-2007-1004826. PMID: 18075961

Therapy

Risk factors for high and low placental weight.
McNamara H, Hutcheon JA, Platt RW, Benjamin A, Kramer MS
Paediatr Perinat Epidemiol 2014 Mar;28(2):97-105. Epub 2013 Dec 20 doi: 10.1111/ppe.12104. PMID: 24354883

Prognosis

Intraplacental Gestational Neoplasms: A Review of Clinically Relevant Diagnostically Challenging Lesions.
Dahl J
Arch Pathol Lab Med 2024 Apr 1;148(4):398-408. doi: 10.5858/arpa.2023-0109-RA. PMID: 37977155
The singular case of multiple chorangioma syndrome in an IVF pregnancy. Analysis of the case and review of literature.
Carlucci S, Stabile G, Sorrentino F, Nappi L, Botta G, Menato G, Masturzo B
Placenta 2021 Jan 1;103:120-123. Epub 2020 Oct 22 doi: 10.1016/j.placenta.2020.10.025. PMID: 33120047
A mystery mass on the placenta.
Ting ELP, Yong SL, Suhashini G, Kang M
Horm Mol Biol Clin Investig 2019 Oct 11;40(2) doi: 10.1515/hmbci-2019-0002. PMID: 31603854
An epidemiological study investigating the relationship between chorangioma and infantile hemangioma.
Selmin A, Foltran F, Chiarelli S, Ciullo R, Gregori D
Pathol Res Pract 2014 Sep;210(9):548-53. Epub 2014 Apr 23 doi: 10.1016/j.prp.2014.04.007. PMID: 24836731
Atypical cellular chorangioma.
Mesia AF, Mo P, Ylagan LR
Arch Pathol Lab Med 1999 Jun;123(6):536-8. doi: 10.5858/1999-123-0536-ACC. PMID: 10383809

Clinical prediction guides

Clinical Outcome in Singleton and Multiple Pregnancies with Placental Chorangioma.
Sirotkina M, Douroudis K, Papadogiannakis N, Westgren M
PLoS One 2016;11(11):e0166562. Epub 2016 Nov 11 doi: 10.1371/journal.pone.0166562. PMID: 27835686Free PMC Article
An epidemiological study investigating the relationship between chorangioma and infantile hemangioma.
Selmin A, Foltran F, Chiarelli S, Ciullo R, Gregori D
Pathol Res Pract 2014 Sep;210(9):548-53. Epub 2014 Apr 23 doi: 10.1016/j.prp.2014.04.007. PMID: 24836731
Review: Exploration of placentation from human beings to ocean-living species.
Soma H, Murai N, Tanaka K, Oguro T, Kokuba H, Yoshihama I, Fujita K, Mineo S, Toda M, Uchida S, Mogoe T
Placenta 2013 Mar;34 Suppl:S17-23. Epub 2013 Jan 16 doi: 10.1016/j.placenta.2012.11.021. PMID: 23332416
Characteristics of histopathological and ultrastructural features of placental villi in pregnant Nepalese women.
Soma H, Hata T, Oguro T, Fujita K, Kudo M, Vaidya U
Med Mol Morphol 2005 Jun;38(2):92-103. doi: 10.1007/s00795-004-0259-y. PMID: 15944816
Chorangiosis and chorangioma in three cohorts of placentas from Nepal, Tibet, and Japan.
Soma H, Watanabe Y, Hata T
Reprod Fertil Dev 1995;7(6):1533-8. doi: 10.1071/rd9951533. PMID: 8743160

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...