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Drug exanthem

MedGen UID:
671064
•Concept ID:
C0595956
•
Disease or Syndrome
SNOMED CT: Drug exanthem (238813009)

Professional guidelines

PubMed

Acute Generalized Exanthematous Pustulosis: Clinical Features, Differential Diagnosis, and Management.
Parisi R, Shah H, Navarini AA, Muehleisen B, Ziv M, Shear NH, Dodiuk-Gad RP
Am J Clin Dermatol 2023 Jul;24(4):557-575. Epub 2023 May 8 doi: 10.1007/s40257-023-00779-3. PMID: 37156992Free PMC Article
Tickborne Diseases: Diagnosis and Management.
Pace EJ, O'Reilly M
Am Fam Physician 2020 May 1;101(9):530-540. PMID: 32352736
Practical Management of Lenalidomide-Related Rash.
Tinsley SM, Kurtin SE, Ridgeway JA
Clin Lymphoma Myeloma Leuk 2015 Jun;15 Suppl:S64-9. doi: 10.1016/j.clml.2015.02.008. PMID: 26297281

Recent clinical studies

Etiology

Assessment of histopathological features of maculopapular viral exanthem and drug-induced exanthem.
Singh S, Khandpur S, Arava S, Rath R, Ramam M, Singh M, Sharma VK, Kabra SK
J Cutan Pathol 2017 Dec;44(12):1038-1048. Epub 2017 Oct 13 doi: 10.1111/cup.13047. PMID: 28914958
Rates of cutaneous reactions to drugs.
Bigby M
Arch Dermatol 2001 Jun;137(6):765-70. PMID: 11405768
Primary and secondary erythema migrans in central Wisconsin.
Melski JW, Reed KD, Mitchell PD, Barth GD
Arch Dermatol 1993 Jun;129(6):709-16. PMID: 8389536
Allergic cutaneous reactions to drugs.
Bigby M, Stern RS, Arndt KA
Prim Care 1989 Sep;16(3):713-27. PMID: 2529577

Diagnosis

Assessment of histopathological features of maculopapular viral exanthem and drug-induced exanthem.
Singh S, Khandpur S, Arava S, Rath R, Ramam M, Singh M, Sharma VK, Kabra SK
J Cutan Pathol 2017 Dec;44(12):1038-1048. Epub 2017 Oct 13 doi: 10.1111/cup.13047. PMID: 28914958
Generalized purpuric drug exanthem with hemorrhagic plaques following bendamustine chemotherapy in a patient with B-prolymphocytic leukemia.
Gavini A, Telang GH, Olszewski AJ
Int J Hematol 2012 Mar;95(3):311-4. doi: 10.1007/s12185-012-1012-2. PMID: 22290027
Primary and secondary erythema migrans in central Wisconsin.
Melski JW, Reed KD, Mitchell PD, Barth GD
Arch Dermatol 1993 Jun;129(6):709-16. PMID: 8389536
Allergic cutaneous reactions to drugs.
Bigby M, Stern RS, Arndt KA
Prim Care 1989 Sep;16(3):713-27. PMID: 2529577

Therapy

Generalized purpuric drug exanthem with hemorrhagic plaques following bendamustine chemotherapy in a patient with B-prolymphocytic leukemia.
Gavini A, Telang GH, Olszewski AJ
Int J Hematol 2012 Mar;95(3):311-4. doi: 10.1007/s12185-012-1012-2. PMID: 22290027
Rates of cutaneous reactions to drugs.
Bigby M
Arch Dermatol 2001 Jun;137(6):765-70. PMID: 11405768
Primary and secondary erythema migrans in central Wisconsin.
Melski JW, Reed KD, Mitchell PD, Barth GD
Arch Dermatol 1993 Jun;129(6):709-16. PMID: 8389536
Drug exanthem in the region of Head's zones.
FISCHER H, KAPPEL I
Dermatol Wochenschr 1957 Aug 17;136(33):875-80. PMID: 13473410

Prognosis

Rates of cutaneous reactions to drugs.
Bigby M
Arch Dermatol 2001 Jun;137(6):765-70. PMID: 11405768
Allergic cutaneous reactions to drugs.
Bigby M, Stern RS, Arndt KA
Prim Care 1989 Sep;16(3):713-27. PMID: 2529577

Clinical prediction guides

Assessment of histopathological features of maculopapular viral exanthem and drug-induced exanthem.
Singh S, Khandpur S, Arava S, Rath R, Ramam M, Singh M, Sharma VK, Kabra SK
J Cutan Pathol 2017 Dec;44(12):1038-1048. Epub 2017 Oct 13 doi: 10.1111/cup.13047. PMID: 28914958

Recent systematic reviews

Rates of cutaneous reactions to drugs.
Bigby M
Arch Dermatol 2001 Jun;137(6):765-70. PMID: 11405768

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