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Chronic sciatica

MedGen UID:
667429
•Concept ID:
C0585052
•
Disease or Syndrome
SNOMED CT: Chronic sciatica (307177001)

Professional guidelines

PubMed

Sciatica of nondisc origin and piriformis syndrome: diagnosis by magnetic resonance neurography and interventional magnetic resonance imaging with outcome study of resulting treatment.
Filler AG, Haynes J, Jordan SE, Prager J, Villablanca JP, Farahani K, McBride DQ, Tsuruda JS, Morisoli B, Batzdorf U, Johnson JP
J Neurosurg Spine 2005 Feb;2(2):99-115. doi: 10.3171/spi.2005.2.2.0099. PMID: 15739520
Targeted methylprednisolone acetate/hyaluronidase/clonidine injection after diagnostic epiduroscopy for chronic sciatica: a prospective, 1-year follow-up study.
Geurts JW, Kallewaard JW, Richardson J, Groen GJ
Reg Anesth Pain Med 2002 Jul-Aug;27(4):343-52. doi: 10.1053/rapm.2002.27175. PMID: 12132057
Lumbar epidural injection for the treatment of chronic sciatica.
Burn JM, Langdon L
Rheumatol Phys Med 1970 Aug;10(7):368-74. doi: 10.1093/rheumatology/10.7.368. PMID: 5458848

Recent clinical studies

Etiology

Acupuncture Modulation of Chronic Neuropathic Pain and Its Association With Brain Functional Properties.
Wei XY, Wang X, Shi GX, Tu JF, Yang JW, Ren MM, Liu JL, Lee CK, Zhou H, Wang ZY, Liu CZ
J Pain 2024 Nov;25(11):104645. Epub 2024 Jul 30 doi: 10.1016/j.jpain.2024.104645. PMID: 39089662
Acupuncture for chronic sciatica: protocol for a multicenter randomised controlled trial.
Yu FT, Liu CZ, Ni GX, Cai GW, Liu ZS, Zhou XQ, Ma CY, Meng XL, Tu JF, Li HW, Yang JW, Yan SY, Fu HY, Xu WT, Li J, Xiang HC, Sun TH, Zhang B, Li MH, Wan WJ, He C, Ji XL, Zhu W, Shi GX, Wang LQ
BMJ Open 2022 May 17;12(5):e054566. doi: 10.1136/bmjopen-2021-054566. PMID: 35580967Free PMC Article
Neural management plus advice to stay active on clinical measures and sciatic neurodynamic for patients with chronic sciatica: Study protocol for a controlled randomised clinical trial.
Corrêa LA, Bittencourt JV, Mainenti Pagnez MA, Mathieson S, Saragiotto BT, Telles GF, Meziat-Filho N, Calazans Nogueira LA
PLoS One 2022;17(2):e0263152. Epub 2022 Feb 4 doi: 10.1371/journal.pone.0263152. PMID: 35120149Free PMC Article
Surgery versus Conservative Care for Persistent Sciatica Lasting 4 to 12 Months.
Bailey CS, Rasoulinejad P, Taylor D, Sequeira K, Miller T, Watson J, Rosedale R, Bailey SI, Gurr KR, Siddiqi F, Glennie A, Urquhart JC
N Engl J Med 2020 Mar 19;382(12):1093-1102. doi: 10.1056/NEJMoa1912658. PMID: 32187469
Trial of Pregabalin for Acute and Chronic Sciatica.
Mathieson S, Maher CG, McLachlan AJ, Latimer J, Koes BW, Hancock MJ, Harris I, Day RO, Billot L, Pik J, Jan S, Lin CC
N Engl J Med 2017 Mar 23;376(12):1111-1120. doi: 10.1056/NEJMoa1614292. PMID: 28328324

Diagnosis

Microdiscectomy Is More Cost-effective Than a 6-Month Nonsurgical Care Regimen for Chronic Radiculopathy.
Glennie RA, Urquhart JC, Koto P, Rasoulinejad P, Taylor D, Sequeira K, Miller T, Watson J, Rosedale R, Bailey SI, Gurr KR, Siddiqi F, Bailey CS
Clin Orthop Relat Res 2022 Mar 1;480(3):574-584. doi: 10.1097/CORR.0000000000002001. PMID: 34597280Free PMC Article
Effect and neurophysiological mechanism of acupuncture in patients with chronic sciatica: protocol for a randomized, patient-assessor blind, sham-controlled clinical trial.
Kim KW, Park K, Park HJ, Jahng GH, Jo DJ, Cho JH, Song EM, Shin WC, Yoon YJ, Kim SJ, Eun S, Song MY
Trials 2019 Jan 16;20(1):56. doi: 10.1186/s13063-018-3164-8. PMID: 30651139Free PMC Article
(18)F-FDG PET/MRI in Chronic Sciatica: Early Results Revealing Spinal and Nonspinal Abnormalities.
Cipriano PW, Yoon D, Gandhi H, Holley D, Thakur D, Hargreaves BA, Kennedy DJ, Smuck MW, Cheng I, Biswal S
J Nucl Med 2018 Jun;59(6):967-972. Epub 2017 Nov 2 doi: 10.2967/jnumed.117.198259. PMID: 29097408
Magnetic resonance neurography evaluation of chronic extraspinal sciatica after remote proximal hamstring injury: a preliminary retrospective analysis.
Bucknor MD, Steinbach LS, Saloner D, Chin CT
J Neurosurg 2014 Aug;121(2):408-14. Epub 2014 May 30 doi: 10.3171/2014.4.JNS13940. PMID: 24878283
Sciatica of nondisc origin and piriformis syndrome: diagnosis by magnetic resonance neurography and interventional magnetic resonance imaging with outcome study of resulting treatment.
Filler AG, Haynes J, Jordan SE, Prager J, Villablanca JP, Farahani K, McBride DQ, Tsuruda JS, Morisoli B, Batzdorf U, Johnson JP
J Neurosurg Spine 2005 Feb;2(2):99-115. doi: 10.3171/spi.2005.2.2.0099. PMID: 15739520

Therapy

Acupuncture for chronic sciatica: protocol for a multicenter randomised controlled trial.
Yu FT, Liu CZ, Ni GX, Cai GW, Liu ZS, Zhou XQ, Ma CY, Meng XL, Tu JF, Li HW, Yang JW, Yan SY, Fu HY, Xu WT, Li J, Xiang HC, Sun TH, Zhang B, Li MH, Wan WJ, He C, Ji XL, Zhu W, Shi GX, Wang LQ
BMJ Open 2022 May 17;12(5):e054566. doi: 10.1136/bmjopen-2021-054566. PMID: 35580967Free PMC Article
Neural management plus advice to stay active on clinical measures and sciatic neurodynamic for patients with chronic sciatica: Study protocol for a controlled randomised clinical trial.
Corrêa LA, Bittencourt JV, Mainenti Pagnez MA, Mathieson S, Saragiotto BT, Telles GF, Meziat-Filho N, Calazans Nogueira LA
PLoS One 2022;17(2):e0263152. Epub 2022 Feb 4 doi: 10.1371/journal.pone.0263152. PMID: 35120149Free PMC Article
Surgery versus Conservative Care for Persistent Sciatica Lasting 4 to 12 Months.
Bailey CS, Rasoulinejad P, Taylor D, Sequeira K, Miller T, Watson J, Rosedale R, Bailey SI, Gurr KR, Siddiqi F, Glennie A, Urquhart JC
N Engl J Med 2020 Mar 19;382(12):1093-1102. doi: 10.1056/NEJMoa1912658. PMID: 32187469
Effect of Gabapentin vs Pregabalin on Pain Intensity in Adults With Chronic Sciatica: A Randomized Clinical Trial.
Robertson K, Marshman LAG, Plummer D, Downs E
JAMA Neurol 2019 Jan 1;76(1):28-34. doi: 10.1001/jamaneurol.2018.3077. PMID: 30326006Free PMC Article
Trial of Pregabalin for Acute and Chronic Sciatica.
Mathieson S, Maher CG, McLachlan AJ, Latimer J, Koes BW, Hancock MJ, Harris I, Day RO, Billot L, Pik J, Jan S, Lin CC
N Engl J Med 2017 Mar 23;376(12):1111-1120. doi: 10.1056/NEJMoa1614292. PMID: 28328324

Prognosis

Acupuncture Modulation of Chronic Neuropathic Pain and Its Association With Brain Functional Properties.
Wei XY, Wang X, Shi GX, Tu JF, Yang JW, Ren MM, Liu JL, Lee CK, Zhou H, Wang ZY, Liu CZ
J Pain 2024 Nov;25(11):104645. Epub 2024 Jul 30 doi: 10.1016/j.jpain.2024.104645. PMID: 39089662
Surgery versus Conservative Care for Persistent Sciatica Lasting 4 to 12 Months.
Bailey CS, Rasoulinejad P, Taylor D, Sequeira K, Miller T, Watson J, Rosedale R, Bailey SI, Gurr KR, Siddiqi F, Glennie A, Urquhart JC
N Engl J Med 2020 Mar 19;382(12):1093-1102. doi: 10.1056/NEJMoa1912658. PMID: 32187469
Trial of Pregabalin for Acute and Chronic Sciatica.
Mathieson S, Maher CG, McLachlan AJ, Latimer J, Koes BW, Hancock MJ, Harris I, Day RO, Billot L, Pik J, Jan S, Lin CC
N Engl J Med 2017 Mar 23;376(12):1111-1120. doi: 10.1056/NEJMoa1614292. PMID: 28328324
Cost-effectiveness and safety of epidural steroids in the management of sciatica.
Price C, Arden N, Coglan L, Rogers P
Health Technol Assess 2005 Aug;9(33):1-58, iii. doi: 10.3310/hta9330. PMID: 16095548
Psychological screening in the surgical treatment of lumbar disc herniation.
Carragee EJ
Clin J Pain 2001 Sep;17(3):215-9. doi: 10.1097/00002508-200109000-00005. PMID: 11587111

Clinical prediction guides

Acupuncture Modulation of Chronic Neuropathic Pain and Its Association With Brain Functional Properties.
Wei XY, Wang X, Shi GX, Tu JF, Yang JW, Ren MM, Liu JL, Lee CK, Zhou H, Wang ZY, Liu CZ
J Pain 2024 Nov;25(11):104645. Epub 2024 Jul 30 doi: 10.1016/j.jpain.2024.104645. PMID: 39089662
Understanding how the research question impacts trial design: Examples from discectomy trials.
Raymond J, Chan VKY, Darsaut TE
Neurochirurgie 2023 Jul;69(4):101460. Epub 2023 Jul 4 doi: 10.1016/j.neuchi.2023.101460. PMID: 37413815
Surgery versus Conservative Care for Persistent Sciatica Lasting 4 to 12 Months.
Bailey CS, Rasoulinejad P, Taylor D, Sequeira K, Miller T, Watson J, Rosedale R, Bailey SI, Gurr KR, Siddiqi F, Glennie A, Urquhart JC
N Engl J Med 2020 Mar 19;382(12):1093-1102. doi: 10.1056/NEJMoa1912658. PMID: 32187469
(18)F-FDG PET/MRI in Chronic Sciatica: Early Results Revealing Spinal and Nonspinal Abnormalities.
Cipriano PW, Yoon D, Gandhi H, Holley D, Thakur D, Hargreaves BA, Kennedy DJ, Smuck MW, Cheng I, Biswal S
J Nucl Med 2018 Jun;59(6):967-972. Epub 2017 Nov 2 doi: 10.2967/jnumed.117.198259. PMID: 29097408
Trial of Pregabalin for Acute and Chronic Sciatica.
Mathieson S, Maher CG, McLachlan AJ, Latimer J, Koes BW, Hancock MJ, Harris I, Day RO, Billot L, Pik J, Jan S, Lin CC
N Engl J Med 2017 Mar 23;376(12):1111-1120. doi: 10.1056/NEJMoa1614292. PMID: 28328324

Recent systematic reviews

Drugs for relief of pain in patients with sciatica: systematic review and meta-analysis.
Pinto RZ, Maher CG, Ferreira ML, Ferreira PH, Hancock M, Oliveira VC, McLachlan AJ, Koes B
BMJ 2012 Feb 13;344:e497. doi: 10.1136/bmj.e497. PMID: 22331277Free PMC Article

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