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Madarosis of eyebrow

MedGen UID:
107912
•Concept ID:
C0578682
•
Disease or Syndrome; Finding
Synonym: Loss of eyebrows
SNOMED CT: Madarosis of eyebrow (422441003); Supraciliary madarosis (422441003); Loss of eyebrows (422441003)

Professional guidelines

PubMed

Acquired causes of eyebrow and eyelash loss: A review and approach to diagnosis and treatment.
Mumford BP, Eisman S, Yip L
Australas J Dermatol 2023 Feb;64(1):28-40. Epub 2022 Nov 1 doi: 10.1111/ajd.13947. PMID: 36320026
Clinical features and orbital anomalies in Fraser syndrome and a review of management options.
Das D, Modaboyina S, Raj S, Agrawal S, Bajaj MS
Indian J Ophthalmol 2022 Jul;70(7):2559-2563. doi: 10.4103/ijo.IJO_2627_21. PMID: 35791156Free PMC Article
Eyebrow growth pattern analysis in patients with eyebrow hypotrichosis after receiving topical treatment: A retrospective study.
Suchonwanit P, Thammarucha S
J Cosmet Dermatol 2020 Jun;19(6):1404-1408. Epub 2019 Sep 21 doi: 10.1111/jocd.13167. PMID: 31541563

Recent clinical studies

Etiology

Microblading Technique for Tattooing of "Hairstrokes" That Simulate Natural Hair: Eyebrow Tattooing and Correction of Medical Conditions.
Hvas D, Serup J
Curr Probl Dermatol 2022;56:141-154. Epub 2023 Jun 1 doi: 10.1159/000529810. PMID: 37263228
Clinical features and orbital anomalies in Fraser syndrome and a review of management options.
Das D, Modaboyina S, Raj S, Agrawal S, Bajaj MS
Indian J Ophthalmol 2022 Jul;70(7):2559-2563. doi: 10.4103/ijo.IJO_2627_21. PMID: 35791156Free PMC Article
Madarosis: a qualitative study to assess perceptions and experience of Australian patients with early breast cancer treated with taxane-based chemotherapy.
Smith K, Winstanley J, Boyle F, O'Reilly A, White M, Antill YC
Support Care Cancer 2018 Feb;26(2):483-489. Epub 2017 Aug 22 doi: 10.1007/s00520-017-3852-z. PMID: 28831569
Ophthalmologic Features of Progeria.
Mantagos IS, Kleinman ME, Kieran MW, Gordon LB
Am J Ophthalmol 2017 Oct;182:126-132. Epub 2017 Jul 27 doi: 10.1016/j.ajo.2017.07.020. PMID: 28756152
Madarosis, milphosis, eyelash trichomegaly, and dermatochalasis.
Vij A, Bergfeld WF
Clin Dermatol 2015 Mar-Apr;33(2):217-26. doi: 10.1016/j.clindermatol.2014.10.013. PMID: 25704941

Diagnosis

Acquired causes of eyebrow and eyelash loss: A review and approach to diagnosis and treatment.
Mumford BP, Eisman S, Yip L
Australas J Dermatol 2023 Feb;64(1):28-40. Epub 2022 Nov 1 doi: 10.1111/ajd.13947. PMID: 36320026
Eyebrow and Eyelash Alopecia: A Clinical Review.
Nguyen B, Hu JK, Tosti A
Am J Clin Dermatol 2023 Jan;24(1):55-67. Epub 2022 Oct 2 doi: 10.1007/s40257-022-00729-5. PMID: 36183302Free PMC Article
Ophthalmologic Features of Progeria.
Mantagos IS, Kleinman ME, Kieran MW, Gordon LB
Am J Ophthalmol 2017 Oct;182:126-132. Epub 2017 Jul 27 doi: 10.1016/j.ajo.2017.07.020. PMID: 28756152
Madarosis, milphosis, eyelash trichomegaly, and dermatochalasis.
Vij A, Bergfeld WF
Clin Dermatol 2015 Mar-Apr;33(2):217-26. doi: 10.1016/j.clindermatol.2014.10.013. PMID: 25704941
Madarosis.
Khong JJ, Casson RJ, Huilgol SC, Selva D
Surv Ophthalmol 2006 Nov-Dec;51(6):550-60. doi: 10.1016/j.survophthal.2006.08.004. PMID: 17134645

Therapy

Eyebrow and Eyelash Loss in Patients With Cancer.
Rose L, Khuhro A, Minta A, Novice M, Novice T, Lustberg MB, Ruddy KJ, Rake EC, Loprinzi CL, Dulmage B
J Drugs Dermatol 2024 May 1;23(5):327-331. doi: 10.36849/JDD.8003. PMID: 38709698
Eyebrow growth pattern analysis in patients with eyebrow hypotrichosis after receiving topical treatment: A retrospective study.
Suchonwanit P, Thammarucha S
J Cosmet Dermatol 2020 Jun;19(6):1404-1408. Epub 2019 Sep 21 doi: 10.1111/jocd.13167. PMID: 31541563
Madarosis: a qualitative study to assess perceptions and experience of Australian patients with early breast cancer treated with taxane-based chemotherapy.
Smith K, Winstanley J, Boyle F, O'Reilly A, White M, Antill YC
Support Care Cancer 2018 Feb;26(2):483-489. Epub 2017 Aug 22 doi: 10.1007/s00520-017-3852-z. PMID: 28831569
Ophthalmologic Features of Progeria.
Mantagos IS, Kleinman ME, Kieran MW, Gordon LB
Am J Ophthalmol 2017 Oct;182:126-132. Epub 2017 Jul 27 doi: 10.1016/j.ajo.2017.07.020. PMID: 28756152
Ruxolitinib found to cause eyelash growth: a case report.
Song J, Song A, Palmares T, Song M, Song H
J Med Case Rep 2017 Jul 12;11(1):189. doi: 10.1186/s13256-017-1304-5. PMID: 28701183Free PMC Article

Prognosis

Eyebrow growth pattern analysis in patients with eyebrow hypotrichosis after receiving topical treatment: A retrospective study.
Suchonwanit P, Thammarucha S
J Cosmet Dermatol 2020 Jun;19(6):1404-1408. Epub 2019 Sep 21 doi: 10.1111/jocd.13167. PMID: 31541563
Ophthalmologic Features of Progeria.
Mantagos IS, Kleinman ME, Kieran MW, Gordon LB
Am J Ophthalmol 2017 Oct;182:126-132. Epub 2017 Jul 27 doi: 10.1016/j.ajo.2017.07.020. PMID: 28756152
Madarosis, milphosis, eyelash trichomegaly, and dermatochalasis.
Vij A, Bergfeld WF
Clin Dermatol 2015 Mar-Apr;33(2):217-26. doi: 10.1016/j.clindermatol.2014.10.013. PMID: 25704941
Unilateral giant coloboma of the upper eyelid associated with other congenital anomalies (33 years follow-up of surgical repair).
Scassellati-Sforzolini G, Scassellati-Sforzolini B
Eur J Ophthalmol 2003 Oct;13(8):714-7. doi: 10.1177/112067210301300809. PMID: 14620177
The changes in hair growth pattern after autologous hair transplantation.
Lee SH, Kim DW, Jun JB, Lee SJ, Kim JC, Kim NH
Dermatol Surg 1999 Aug;25(8):605-9. doi: 10.1046/j.1524-4725.1999.99003.x. PMID: 10491042

Clinical prediction guides

Eyebrow growth pattern analysis in patients with eyebrow hypotrichosis after receiving topical treatment: A retrospective study.
Suchonwanit P, Thammarucha S
J Cosmet Dermatol 2020 Jun;19(6):1404-1408. Epub 2019 Sep 21 doi: 10.1111/jocd.13167. PMID: 31541563
The value of dermoscopy in diagnosing eyebrow loss in patients with alopecia areata and frontal fibrosing alopecia.
Waśkiel-Burnat A, Rakowska A, Kurzeja M, Czuwara J, Sikora M, Olszewska M, Rudnicka L
J Eur Acad Dermatol Venereol 2019 Jan;33(1):213-219. Epub 2018 Oct 31 doi: 10.1111/jdv.15279. PMID: 30290016
Ophthalmologic Features of Progeria.
Mantagos IS, Kleinman ME, Kieran MW, Gordon LB
Am J Ophthalmol 2017 Oct;182:126-132. Epub 2017 Jul 27 doi: 10.1016/j.ajo.2017.07.020. PMID: 28756152
The changes in hair growth pattern after autologous hair transplantation.
Lee SH, Kim DW, Jun JB, Lee SJ, Kim JC, Kim NH
Dermatol Surg 1999 Aug;25(8):605-9. doi: 10.1046/j.1524-4725.1999.99003.x. PMID: 10491042

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