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Idiopathic polymyositis

MedGen UID:
108216
•Concept ID:
C0554591
•
Disease or Syndrome
Synonyms: Idiopathic Polymyositides; Idiopathic Polymyositis; Polymyositides, Idiopathic; Polymyositis, Idiopathic
SNOMED CT: Idiopathic polymyositis (281357005)

Professional guidelines

PubMed

Updated consensus statement: Intravenous immunoglobulin in the treatment of neuromuscular disorders report of the AANEM ad hoc committee.
Tavee J, Brannagan TH 3rd, Lenihan MW, Muppidi S, Kellermeyer L, D Donofrio P; AANEM
Muscle Nerve 2023 Oct;68(4):356-374. Epub 2023 Jul 11 doi: 10.1002/mus.27922. PMID: 37432872
Differential diagnosis of chronic idiopathic polymyositis and neuromyositis.
Milanov I, Ishpekova B
Electromyogr Clin Neurophysiol 1998 Apr-May;38(3):183-7. PMID: 9637945
Inclusion body myositis presenting as treatment-resistant polymyositis.
Calabrese LH, Mitsumoto H, Chou SM
Arthritis Rheum 1987 Apr;30(4):397-403. doi: 10.1002/art.1780300406. PMID: 3034295

Recent clinical studies

Etiology

Scleroderma-polymyositis overlap syndrome versus idiopathic polymyositis and systemic sclerosis: a descriptive study on clinical features and myopathology.
Bhansing KJ, Lammens M, Knaapen HK, van Riel PL, van Engelen BG, Vonk MC
Arthritis Res Ther 2014 May 13;16(3):R111. doi: 10.1186/ar4562. PMID: 24886750Free PMC Article
Efficacy and limitations of pulse cyclophosphamide therapy in polymyositis and dermatomyositis.
Nagappa M, Taly AB, Sinha S, Gayathri N, Bindu PS, Mahadevan A, Yasha T
J Clin Neuromuscul Dis 2013 Jun;14(4):161-8. doi: 10.1097/CND.0b013e31828ee913. PMID: 23703010
Polymyositis as a manifestation of chronic graft-versus-host disease.
Stevens AM, Sullivan KM, Nelson JL
Rheumatology (Oxford) 2003 Jan;42(1):34-9. doi: 10.1093/rheumatology/keg025. PMID: 12509610
Idiopathic polymyositis and glomerulonephritis.
Valenzuela OF, Reiser IW, Porush JG
J Nephrol 2001 Mar-Apr;14(2):120-4. PMID: 11411013
Postpartum autoimmune thyroid syndrome: a model of aggravation of autoimmune disease.
Amino N, Tada H, Hidaka Y
Thyroid 1999 Jul;9(7):705-13. doi: 10.1089/thy.1999.9.705. PMID: 10447018

Diagnosis

Scleroderma-polymyositis overlap syndrome versus idiopathic polymyositis and systemic sclerosis: a descriptive study on clinical features and myopathology.
Bhansing KJ, Lammens M, Knaapen HK, van Riel PL, van Engelen BG, Vonk MC
Arthritis Res Ther 2014 May 13;16(3):R111. doi: 10.1186/ar4562. PMID: 24886750Free PMC Article
Graft-versus-host disease-related polymyositis.
Maillard-Lefebvre H, Morell-Dubois S, Lambert M, Charlanne H, Launay D, Hachulla E, Yakoub-Agh I, Hatron PY
Clin Rheumatol 2010 Apr;29(4):431-33. doi: 10.1007/s10067-009-1350-5. PMID: 20069327
20. Immunologic neuromuscular disorders.
Chitnis T, Khoury SJ
J Allergy Clin Immunol 2003 Feb;111(2 Suppl):S659-68. doi: 10.1067/mai.2003.92. PMID: 12592311
Polymyositis as a manifestation of chronic graft-versus-host disease.
Stevens AM, Sullivan KM, Nelson JL
Rheumatology (Oxford) 2003 Jan;42(1):34-9. doi: 10.1093/rheumatology/keg025. PMID: 12509610
Differential diagnosis of chronic idiopathic polymyositis and neuromyositis.
Milanov I, Ishpekova B
Electromyogr Clin Neurophysiol 1998 Apr-May;38(3):183-7. PMID: 9637945

Therapy

Efficacy and limitations of pulse cyclophosphamide therapy in polymyositis and dermatomyositis.
Nagappa M, Taly AB, Sinha S, Gayathri N, Bindu PS, Mahadevan A, Yasha T
J Clin Neuromuscul Dis 2013 Jun;14(4):161-8. doi: 10.1097/CND.0b013e31828ee913. PMID: 23703010
Anti-PL7 antisynthetase syndrome under interferon therapy.
Aouba A, Georgin-Lavialle S, Terrier B, Guillevin L, Authier FJ
Joint Bone Spine 2011 Jan;78(1):94-7. Epub 2010 Sep 18 doi: 10.1016/j.jbspin.2010.07.012. PMID: 20851661
Graft-versus-host disease-related polymyositis.
Maillard-Lefebvre H, Morell-Dubois S, Lambert M, Charlanne H, Launay D, Hachulla E, Yakoub-Agh I, Hatron PY
Clin Rheumatol 2010 Apr;29(4):431-33. doi: 10.1007/s10067-009-1350-5. PMID: 20069327
Idiopathic polymyositis and glomerulonephritis.
Valenzuela OF, Reiser IW, Porush JG
J Nephrol 2001 Mar-Apr;14(2):120-4. PMID: 11411013
Idiopathic polymyositis complicated by arthritis and mesangial proliferative glomerulonephritis: case report and review of the literature.
Frost NA, Morand EF, Hall CL, Maddison PJ, Bhalla AK
Br J Rheumatol 1993 Oct;32(10):929-31. doi: 10.1093/rheumatology/32.10.929. PMID: 8402004

Prognosis

Genetic Myopathies Initially Diagnosed and Treated as Inflammatory Myopathy.
Tarnopolsky MA, Hatcher E, Shupak R
Can J Neurol Sci 2016 May;43(3):381-4. Epub 2016 Feb 25 doi: 10.1017/cjn.2015.386. PMID: 26911292
Polymyositis as a manifestation of chronic graft-versus-host disease.
Stevens AM, Sullivan KM, Nelson JL
Rheumatology (Oxford) 2003 Jan;42(1):34-9. doi: 10.1093/rheumatology/keg025. PMID: 12509610
Idiopathic polymyositis and glomerulonephritis.
Valenzuela OF, Reiser IW, Porush JG
J Nephrol 2001 Mar-Apr;14(2):120-4. PMID: 11411013
Postpartum autoimmune thyroid syndrome: a model of aggravation of autoimmune disease.
Amino N, Tada H, Hidaka Y
Thyroid 1999 Jul;9(7):705-13. doi: 10.1089/thy.1999.9.705. PMID: 10447018
Neurologic complications of graft-versus-host disease.
Nelson KR, McQuillen MP
Neurol Clin 1988 May;6(2):389-403. PMID: 3047548

Clinical prediction guides

A CASE OF POLYMYOSITIS WITH INTERSTITIAL LUNG DISEASE ONSET.
Enache A, Bădulescu M, Burlui A, Cardoneanu A, Stamate IG, Mihăescu T, Rezuş E
Rev Med Chir Soc Med Nat Iasi 2015 Oct-Dec;119(4):1055-9. PMID: 26793849
Postpartum autoimmune thyroid syndrome: a model of aggravation of autoimmune disease.
Amino N, Tada H, Hidaka Y
Thyroid 1999 Jul;9(7):705-13. doi: 10.1089/thy.1999.9.705. PMID: 10447018
Expression of NCAM (neural cell adhesion molecule) in mitochondrial myopathy.
Heuss D, Engelhardt A, Göbel H, Neundörfer B
Clin Neuropathol 1995 Nov-Dec;14(6):331-6. PMID: 8605739
Microvascular changes in skeletal muscle in idiopathic inflammatory myopathy.
Estruch R, Grau JM, Fernández-Solá J, Casademont J, Monforte R, Urbano-Márquez A
Hum Pathol 1992 Aug;23(8):888-95. doi: 10.1016/0046-8177(92)90400-w. PMID: 1644434
Neurologic complications of graft-versus-host disease.
Nelson KR, McQuillen MP
Neurol Clin 1988 May;6(2):389-403. PMID: 3047548

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