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Fasciculations, Skeletal Muscle

MedGen UID:
108150
•Concept ID:
C0541957
•
Finding
Synonyms: Fasciculation, Skeletal Muscle; Muscle Fasciculation, Skeletal; Muscle Fasciculations, Skeletal; Skeletal Muscle Fasciculation; Skeletal Muscle Fasciculations

Professional guidelines

PubMed

Awaji criteria for the diagnosis of amyotrophic lateral sclerosis in Hanoi, Vietnam.
Van Nguyen T, Tran TA, Vu HT
Neurol Sci 2022 Jan;43(1):393-398. Epub 2021 May 22 doi: 10.1007/s10072-021-05333-9. PMID: 34023955
Diagnosis and management of motor neurone disease.
Orrell RW
Practitioner 2016 Sep;260(1796):17-21. PMID: 29116729
Mechanisms of toxicity, clinical features, and management of acute chlorophenoxy herbicide poisoning: a review.
Bradberry SM, Watt BE, Proudfoot AT, Vale JA
J Toxicol Clin Toxicol 2000;38(2):111-22. doi: 10.1081/clt-100100925. PMID: 10778907

Recent clinical studies

Etiology

Autoimmune neuromyotonia.
Comperat L, Pegat A, Honnorat J, Joubert B
Curr Opin Neurol 2022 Oct 1;35(5):597-603. Epub 2022 Aug 19 doi: 10.1097/WCO.0000000000001104. PMID: 35989569
Accuracy of muscle fasciculations for the diagnosis of later-onset spinal muscle atrophy.
Dos Santos MAR, Brighente SF, Massignan A, Tenório RB, Makariewicz LL, Moreira AL, Saute JA
Neuromuscul Disord 2022 Sep;32(9):763-768. Epub 2022 Jul 14 doi: 10.1016/j.nmd.2022.07.395. PMID: 35879189
Fasciculations in Children.
Choi HW
Pediatr Neurol 2021 Dec;125:40-47. Epub 2021 Sep 6 doi: 10.1016/j.pediatrneurol.2021.08.008. PMID: 34628142
Transplacental lidocaine intoxication.
Demeulemeester V, Van Hautem H, Cools F, Lefevere J
J Neonatal Perinatal Med 2018;11(4):439-441. doi: 10.3233/NPM-1791. PMID: 30149475
A prospective study of benign fasciculation syndrome and anxiety.
Filippakis A, Jara J, Ventura N, Scala S, Scopa C, Ruthazer R, Karakis I, Srinivasan J, Russell JA, Ho DT
Muscle Nerve 2018 Dec;58(6):852-854. Epub 2018 Sep 11 doi: 10.1002/mus.26193. PMID: 30028521

Diagnosis

Autoimmune neuromyotonia.
Comperat L, Pegat A, Honnorat J, Joubert B
Curr Opin Neurol 2022 Oct 1;35(5):597-603. Epub 2022 Aug 19 doi: 10.1097/WCO.0000000000001104. PMID: 35989569
Neuromuscular hyperexcitability syndromes.
De Wel B, Claeys KG
Curr Opin Neurol 2021 Oct 1;34(5):714-720. doi: 10.1097/WCO.0000000000000963. PMID: 34914668
Fasciculations in Children.
Choi HW
Pediatr Neurol 2021 Dec;125:40-47. Epub 2021 Sep 6 doi: 10.1016/j.pediatrneurol.2021.08.008. PMID: 34628142
Fasciculating toxicity.
Ranjan A, Jamshed N, Aggarwal P, Upadhyay V
Am J Emerg Med 2019 Apr;37(4):798.e1-798.e2. Epub 2019 Jan 21 doi: 10.1016/j.ajem.2019.01.033. PMID: 30686539
Isaacs syndrome: A review.
Ahmed A, Simmons Z
Muscle Nerve 2015 Jul;52(1):5-12. Epub 2015 Mar 31 doi: 10.1002/mus.24632. PMID: 25736532

Therapy

Fasciculating toxicity.
Ranjan A, Jamshed N, Aggarwal P, Upadhyay V
Am J Emerg Med 2019 Apr;37(4):798.e1-798.e2. Epub 2019 Jan 21 doi: 10.1016/j.ajem.2019.01.033. PMID: 30686539
Transplacental lidocaine intoxication.
Demeulemeester V, Van Hautem H, Cools F, Lefevere J
J Neonatal Perinatal Med 2018;11(4):439-441. doi: 10.3233/NPM-1791. PMID: 30149475
Neuromyotonia.
Newsom-Davis J
Rev Neurol (Paris) 2004 May;160(5 Pt 2):S85-9. doi: 10.1016/s0035-3787(04)71010-3. PMID: 15269665
Precurarization.
Cannon JE
Can J Anaesth 1994 Mar;41(3):177-83. doi: 10.1007/BF03009828. PMID: 8187253
Suxamethonium.
Durant NN, Katz RL
Br J Anaesth 1982 Feb;54(2):195-208. doi: 10.1093/bja/54.2.195. PMID: 7037028

Prognosis

Normal and abnormal spontaneous activity.
Rubin DI
Handb Clin Neurol 2019;160:257-279. doi: 10.1016/B978-0-444-64032-1.00017-5. PMID: 31277853
How useful is muscle ultrasound in the diagnostic workup of neuromuscular diseases?
van Alfen N, Gijsbertse K, de Korte CL
Curr Opin Neurol 2018 Oct;31(5):568-574. doi: 10.1097/WCO.0000000000000589. PMID: 30028736
A prospective study of benign fasciculation syndrome and anxiety.
Filippakis A, Jara J, Ventura N, Scala S, Scopa C, Ruthazer R, Karakis I, Srinivasan J, Russell JA, Ho DT
Muscle Nerve 2018 Dec;58(6):852-854. Epub 2018 Sep 11 doi: 10.1002/mus.26193. PMID: 30028521
Disorders of motor neurons manifested by hyperactivity.
Grapperon AM, Attarian S
Rev Neurol (Paris) 2017 May;173(5):345-351. Epub 2017 Apr 28 doi: 10.1016/j.neurol.2017.04.002. PMID: 28457490
Skeletal muscle ultrasound.
Pillen S, van Alfen N
Neurol Res 2011 Dec;33(10):1016-24. doi: 10.1179/1743132811Y.0000000010. PMID: 22196753

Clinical prediction guides

Observation on the Effect of Rehabilitative Physical Training on Sports Injuries under Ultrasound Image Examination.
Wang L, Wang H
Scanning 2022;2022:9998265. Epub 2022 Jun 29 doi: 10.1155/2022/9998265. PMID: 35832298Free PMC Article
Fasciculations in Children.
Choi HW
Pediatr Neurol 2021 Dec;125:40-47. Epub 2021 Sep 6 doi: 10.1016/j.pediatrneurol.2021.08.008. PMID: 34628142
How useful is muscle ultrasound in the diagnostic workup of neuromuscular diseases?
van Alfen N, Gijsbertse K, de Korte CL
Curr Opin Neurol 2018 Oct;31(5):568-574. doi: 10.1097/WCO.0000000000000589. PMID: 30028736
Lower motor neuron dysfunction in ALS.
de Carvalho M, Swash M
Clin Neurophysiol 2016 Jul;127(7):2670-81. Epub 2016 Apr 6 doi: 10.1016/j.clinph.2016.03.024. PMID: 27117334
Skeletal muscle ultrasound.
Pillen S, van Alfen N
Neurol Res 2011 Dec;33(10):1016-24. doi: 10.1179/1743132811Y.0000000010. PMID: 22196753

Recent systematic reviews

Preoperative pregabalin prevents succinylcholine-induced fasciculation and myalgia: A meta-analysis of randomized trials.
Vélez PA, Lara-Erazo V, Caballero-Lozada AF, Botero A, Lozada G, Velásquez AF, Villegas LM, Zorrilla-Vaca A
Rev Esp Anestesiol Reanim (Engl Ed) 2024 Apr;71(4):324-331. Epub 2023 Sep 4 doi: 10.1016/j.redare.2022.12.002. PMID: 37673208
The Association Between Benign Fasciculations and Health Anxiety: A Report of Two Cases and a Systematic Review of the Literature.
Blackman G, Cherfi Y, Morrin H, Ellis CM, Bashford J, Ruths F, David AS
Psychosomatics 2019 Sep-Oct;60(5):499-507. Epub 2019 Apr 10 doi: 10.1016/j.psym.2019.04.001. PMID: 31174866

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