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Cryptogenic Chronic Hepatitis

MedGen UID:
101133
•Concept ID:
C0524611
•
Disease or Syndrome
Synonyms: Chronic Hepatitis, Cryptogenic; Hepatitis, Chronic, Cryptogenic; Hepatitis, Cryptogenic Chronic

Professional guidelines

PubMed

Clinical and obstetrical management of pregnant women with autoimmune hepatitis complicated by moderate or severe thrombocytopenia.
Nomuras RM, Kleine RT, Igai AM, Francisco RP, Zugaib M
Rev Assoc Med Bras (1992) 2013 Jan-Feb;59(1):28-34. PMID: 23440139
Efficacy of carcinogenic embryonic antigen in differential diagnosis of diseases of pancreas and liver--a comparative study in a tertiary care hospital of Western Nepal.
Mittal A, Farooqui SM, Pyrtuh S, Poudel B, Sathian B, Yadav SK
Asian Pac J Cancer Prev 2012;13(1):275-7. doi: 10.7314/apjcp.2012.13.1.275. PMID: 22502684
The role of histologic evaluation in the diagnosis and management of autoimmune hepatitis and its variants.
Carpenter HA, Czaja AJ
Clin Liver Dis 2002 Aug;6(3):685-705. doi: 10.1016/s1089-3261(02)00022-3. PMID: 12362575

Recent clinical studies

Etiology

Cryptogenic chronic hepatitis and its changing guise in adults.
Czaja AJ
Dig Dis Sci 2011 Dec;56(12):3421-38. Epub 2011 Jun 7 doi: 10.1007/s10620-011-1769-9. PMID: 21647651
Corticosteroid-responsive cryptogenic chronic hepatitis: evidence for seronegative autoimmune hepatitis.
Gassert DJ, Garcia H, Tanaka K, Reinus JF
Dig Dis Sci 2007 Sep;52(9):2433-7. Epub 2007 Apr 12 doi: 10.1007/s10620-006-9665-4. PMID: 17429719
Are hepatitis G virus and TT virus involved in cryptogenic chronic liver disease?
Di SR, Ferraro D, Bonura C, Lo PG, Lacono O, Di Marco V, Craxì A
Dig Liver Dis 2002 Jan;34(1):53-8. doi: 10.1016/s1590-8658(02)80060-3. PMID: 11926574
Is severe cryptogenic chronic hepatitis similar to autoimmune hepatitis?
Kaymakoglu S, Cakaloglu Y, Demir K, Türkoglu S, Badur S, Gürel S, Beşişik F, Cevikbaş U, Okten A
J Hepatol 1998 Jan;28(1):78-83. doi: 10.1016/s0168-8278(98)80205-5. PMID: 9537867
Idiopathic adulthood ductopenia: an update.
Ludwig J
Mayo Clin Proc 1998 Mar;73(3):285-91. doi: 10.4065/73.3.285. PMID: 9511789

Diagnosis

Seronegative occult hepatitis C virus infection: clinical implications.
Carreño V
J Clin Virol 2014 Nov;61(3):315-20. Epub 2014 Sep 28 doi: 10.1016/j.jcv.2014.09.007. PMID: 25304062
Cryptogenic chronic hepatitis and its changing guise in adults.
Czaja AJ
Dig Dis Sci 2011 Dec;56(12):3421-38. Epub 2011 Jun 7 doi: 10.1007/s10620-011-1769-9. PMID: 21647651
The role of histologic evaluation in the diagnosis and management of autoimmune hepatitis and its variants.
Carpenter HA, Czaja AJ
Clin Liver Dis 2002 Aug;6(3):685-705. doi: 10.1016/s1089-3261(02)00022-3. PMID: 12362575
Idiopathic adulthood ductopenia: an update.
Ludwig J
Mayo Clin Proc 1998 Mar;73(3):285-91. doi: 10.4065/73.3.285. PMID: 9511789
The variant forms of autoimmune hepatitis.
Czaja AJ
Ann Intern Med 1996 Oct 1;125(7):588-98. doi: 10.7326/0003-4819-125-7-199610010-00009. PMID: 8815758

Therapy

Cryptogenic chronic hepatitis and its changing guise in adults.
Czaja AJ
Dig Dis Sci 2011 Dec;56(12):3421-38. Epub 2011 Jun 7 doi: 10.1007/s10620-011-1769-9. PMID: 21647651
Corticosteroid-responsive cryptogenic chronic hepatitis: evidence for seronegative autoimmune hepatitis.
Gassert DJ, Garcia H, Tanaka K, Reinus JF
Dig Dis Sci 2007 Sep;52(9):2433-7. Epub 2007 Apr 12 doi: 10.1007/s10620-006-9665-4. PMID: 17429719
Is severe cryptogenic chronic hepatitis similar to autoimmune hepatitis?
Kaymakoglu S, Cakaloglu Y, Demir K, Türkoglu S, Badur S, Gürel S, Beşişik F, Cevikbaş U, Okten A
J Hepatol 1998 Jan;28(1):78-83. doi: 10.1016/s0168-8278(98)80205-5. PMID: 9537867
Association of autoimmune hepatitis with HLA-Bw54 and DR4 in Japanese patients.
Seki T, Kiyosawa K, Inoko H, Ota M
Hepatology 1990 Dec;12(6):1300-4. doi: 10.1002/hep.1840120609. PMID: 2175292

Prognosis

Cryptogenic chronic hepatitis and its changing guise in adults.
Czaja AJ
Dig Dis Sci 2011 Dec;56(12):3421-38. Epub 2011 Jun 7 doi: 10.1007/s10620-011-1769-9. PMID: 21647651
Corticosteroid-responsive cryptogenic chronic hepatitis: evidence for seronegative autoimmune hepatitis.
Gassert DJ, Garcia H, Tanaka K, Reinus JF
Dig Dis Sci 2007 Sep;52(9):2433-7. Epub 2007 Apr 12 doi: 10.1007/s10620-006-9665-4. PMID: 17429719
Useful parameters for distinguishing nonalcoholic steatohepatitis with mild steatosis from cryptogenic chronic hepatitis in the Japanese population.
Tanaka N, Tanaka E, Sheena Y, Komatsu M, Okiyama W, Misawa N, Muto H, Umemura T, Ichijo T, Matsumoto A, Yoshizawa K, Horiuchi A, Kiyosawa K
Liver Int 2006 Oct;26(8):956-63. doi: 10.1111/j.1478-3231.2006.01338.x. PMID: 16953836
Idiopathic adulthood ductopenia: an update.
Ludwig J
Mayo Clin Proc 1998 Mar;73(3):285-91. doi: 10.4065/73.3.285. PMID: 9511789
Impact of international autoimmune hepatitis group scoring system in definition of autoimmune hepatitis. An Italian experience.
Bianchi FB, Cassani F, Lenzi M, Ballardini G, Muratori L, Giostra F, Zauli D
Dig Dis Sci 1996 Jan;41(1):166-71. doi: 10.1007/BF02208600. PMID: 8565751

Clinical prediction guides

Cryptogenic chronic hepatitis and its changing guise in adults.
Czaja AJ
Dig Dis Sci 2011 Dec;56(12):3421-38. Epub 2011 Jun 7 doi: 10.1007/s10620-011-1769-9. PMID: 21647651
Pathogenesis and clinical significance of liver injury in celiac disease.
Volta U
Clin Rev Allergy Immunol 2009 Feb;36(1):62-70. doi: 10.1007/s12016-008-8086-x. PMID: 18496773
Are hepatitis G virus and TT virus involved in cryptogenic chronic liver disease?
Di SR, Ferraro D, Bonura C, Lo PG, Lacono O, Di Marco V, Craxì A
Dig Liver Dis 2002 Jan;34(1):53-8. doi: 10.1016/s1590-8658(02)80060-3. PMID: 11926574
Is severe cryptogenic chronic hepatitis similar to autoimmune hepatitis?
Kaymakoglu S, Cakaloglu Y, Demir K, Türkoglu S, Badur S, Gürel S, Beşişik F, Cevikbaş U, Okten A
J Hepatol 1998 Jan;28(1):78-83. doi: 10.1016/s0168-8278(98)80205-5. PMID: 9537867
The variant forms of autoimmune hepatitis.
Czaja AJ
Ann Intern Med 1996 Oct 1;125(7):588-98. doi: 10.7326/0003-4819-125-7-199610010-00009. PMID: 8815758

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