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Generalized myokymia

MedGen UID:
96884
•Concept ID:
C0474520
•
Sign or Symptom
Synonyms: Generalized Myokymia; Generalized Myokymias; Myokymia, Generalized; Myokymias, Generalized
SNOMED CT: Generalized myokymia (250079008)

Professional guidelines

PubMed

Ocular neuromyotonia: differential diagnosis and treatment.
Roper-Hall G, Chung SM, Cruz OA
Strabismus 2013 Jun;21(2):131-6. doi: 10.3109/09273972.2013.787635. PMID: 23713937
Management of voltage-gated potassium channel antibody disorders.
Merchut MP
Neurol Clin 2010 Nov;28(4):941-59. doi: 10.1016/j.ncl.2010.03.024. PMID: 20816272
The place of the botulinum toxin in the management of multiple sclerosis.
Habek M, Karni A, Balash Y, Gurevich T
Clin Neurol Neurosurg 2010 Sep;112(7):592-6. Epub 2010 Jul 8 doi: 10.1016/j.clineuro.2010.04.010. PMID: 20615606

Recent clinical studies

Etiology

Myokymia and neuromyotonia in veterinary medicine: a comparison with peripheral nerve hyperexcitability syndrome in humans.
Vanhaesebrouck AE, Bhatti SF, Franklin RJ, Van Ham L
Vet J 2013 Aug;197(2):153-62. Epub 2013 Apr 11 doi: 10.1016/j.tvjl.2013.03.002. PMID: 23583699
Idiopathic generalized myokymia.
Jamieson PW, Katirji MB
Muscle Nerve 1994 Jan;17(1):42-51. doi: 10.1002/mus.880170106. PMID: 8264701

Diagnosis

Generalized myokymia, or neuromyotonia, or both in dogs with or without spinocerebellar ataxia.
Vanhaesebrouck A, Van Poucke M, Stee K, Granger N, Ives E, Van Soens I, Cornelis I, Bossens K, Peelman L, Van Ham L, Bhatti SFM
J Vet Intern Med 2023 Nov-Dec;37(6):2310-2314. Epub 2023 Oct 31 doi: 10.1111/jvim.16892. PMID: 37905444Free PMC Article
Myokymia and neuromyotonia in veterinary medicine: a comparison with peripheral nerve hyperexcitability syndrome in humans.
Vanhaesebrouck AE, Bhatti SF, Franklin RJ, Van Ham L
Vet J 2013 Aug;197(2):153-62. Epub 2013 Apr 11 doi: 10.1016/j.tvjl.2013.03.002. PMID: 23583699
Stiff man-like syndrome and generalized myokymia in spinocerebellar ataxia type 3.
Berciano J, Infante J, García A, de Pablos C, Amer G, Polo JM, Volpini V, Combarros O
Mov Disord 2006 Jul;21(7):1031-5. doi: 10.1002/mds.20865. PMID: 16552763
Generalized myokymia as a unique association with gluten-sensitive enteropathy.
Beydoun SR, Copeland DD, Korula J
Eur Neurol 2000;44(4):254-5. doi: 10.1159/000008249. PMID: 11096230
Idiopathic generalized myokymia.
Jamieson PW, Katirji MB
Muscle Nerve 1994 Jan;17(1):42-51. doi: 10.1002/mus.880170106. PMID: 8264701

Therapy

Neuromyotonia in mice with hereditary myelinopathies.
Zielasek J, Martini R, Suter U, Toyka KV
Muscle Nerve 2000 May;23(5):696-701. doi: 10.1002/(sici)1097-4598(200005)23:5<696::aid-mus5>3.0.co;2-w. PMID: 10797391
Isaacs' syndrome with muscle hypertrophy reversed by phenytoin therapy.
Zisfein J, Sivak M, Aron AM, Bender AN
Arch Neurol 1983 Apr;40(4):241-2. doi: 10.1001/archneur.1983.04050040071012. PMID: 6830473
Generalized myokymia and gold therapy.
Mitsumoto H, Wilbourn AJ, Subramony SH
Arch Neurol 1982 Jul;39(7):449-50. doi: 10.1001/archneur.1982.00510190067026. PMID: 7103785
Clinical and morphological features of gold neuropathy.
Katrak SM, Pollock M, O'Brien CP, Nukada H, Allpress S, Calder C, Palmer DG, Grennan DM, McCormack PL, Laurent MR
Brain 1980 Sep;103(3):671-93. doi: 10.1093/brain/103.3.671. PMID: 6251941

Clinical prediction guides

Neuromyotonia in mice with hereditary myelinopathies.
Zielasek J, Martini R, Suter U, Toyka KV
Muscle Nerve 2000 May;23(5):696-701. doi: 10.1002/(sici)1097-4598(200005)23:5<696::aid-mus5>3.0.co;2-w. PMID: 10797391
Idiopathic generalized myokymia.
Jamieson PW, Katirji MB
Muscle Nerve 1994 Jan;17(1):42-51. doi: 10.1002/mus.880170106. PMID: 8264701

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