U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Inflammatory linear verrucous epidermal nevus(ILVEN)

MedGen UID:
96878
•Concept ID:
C0473574
•
Neoplastic Process
Synonyms: ILVEN; Inflammatory linear verrucous epidermal naevus
SNOMED CT: Inflammatory linear verrucous epidermal nevus (399995006); ILVEN - Inflammatory linear verrucous epidermal nevus (399995006)
 
Monarch Initiative: MONDO:0019318
Orphanet: ORPHA79466

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInflammatory linear verrucous epidermal nevus
Follow this link to review classifications for Inflammatory linear verrucous epidermal nevus in Orphanet.

Professional guidelines

PubMed

Inflammatory linear verrucous epidermal nevus should be genotyped to direct treatment and genetic counseling.
Polubothu S, Riachi M, Stadnik P, Ogunbiyi O, Brändli-Wälchli R, Cullup T, Sebire NJ, Pittman A, Kinsler VA
J Am Acad Dermatol 2024 Jun;90(6):1279-1280. Epub 2024 Feb 14 doi: 10.1016/j.jaad.2024.01.075. PMID: 38360177

Recent clinical studies

Etiology

Inflammatory linear verrucous epidermal nevus (ILVEN) encompasses a spectrum of inflammatory mosaic disorders.
Atzmony L, Ugwu N, Hamilton C, Paller AS, Zech L, Antaya RJ, Choate KA
Pediatr Dermatol 2022 Nov;39(6):903-907. Epub 2022 Jul 19 doi: 10.1111/pde.15094. PMID: 35853659Free PMC Article
Differences in clinical characteristics and lesion proteomics between inflammatory linear verrucous epidermal nevus and local verrucous epidermal nevus.
Yuan T, Lu XH, Tang B Mr, Chang XL, He CF, Wang J, Ci C
J Proteomics 2022 May 30;260:104554. Epub 2022 Mar 11 doi: 10.1016/j.jprot.2022.104554. PMID: 35283356
Epidermal nevus syndrome.
Chatproedprai S, Wananukul S, Prasarnnaem T, Noppakun N
Int J Dermatol 2007 Aug;46(8):858-60. doi: 10.1111/j.1365-4632.2007.03085.x. PMID: 17651173
Transposable elements and the lines of Blaschko: a new perspective.
Happle R
Dermatology 2002;204(1):4-7. doi: 10.1159/000051801. PMID: 11834841
The CHILD nevus: a distinct skin disorder.
Happle R, Mittag H, Küster W
Dermatology 1995;191(3):210-6. doi: 10.1159/000246548. PMID: 8534939

Diagnosis

Inflammatory linear verrucous epidermal nevus: A paradigm of progress.
Heymann WR
J Am Acad Dermatol 2024 Jun;90(6):1159-1160. Epub 2024 Mar 28 doi: 10.1016/j.jaad.2024.03.018. PMID: 38552904
Inflammatory linear verrucous epidermal nevus (ILVEN) encompasses a spectrum of inflammatory mosaic disorders.
Atzmony L, Ugwu N, Hamilton C, Paller AS, Zech L, Antaya RJ, Choate KA
Pediatr Dermatol 2022 Nov;39(6):903-907. Epub 2022 Jul 19 doi: 10.1111/pde.15094. PMID: 35853659Free PMC Article
Inflammatory linear verrucous epidermal nevus in a patient with diabetes.
Htira Y, Mami FB
Pan Afr Med J 2022;41:139. Epub 2022 Feb 17 doi: 10.11604/pamj.2022.41.139.33468. PMID: 35519162Free PMC Article
Verruciform xanthoma overlying inflammatory linear verrucous epidermal nevus and in broad segmental distribution.
Singh S, Khandpur S, Agarwal S
BMJ Case Rep 2018 Oct 17;2018 doi: 10.1136/bcr-2018-225964. PMID: 30337284Free PMC Article
Linear psoriasis.
Chien P Jr, Rosenman K, Cheung W, Wang N, Sanchez M
Dermatol Online J 2009 Aug 15;15(8):4. PMID: 19891912

Therapy

Inflammatory linear verrucous epidermal nevus in groin and labia with claudication: Successfully treated with photodynamic therapy.
Wei L, Yu L, Zou L, Ma L
Photodiagnosis Photodyn Ther 2024 Feb;45:103970. Epub 2024 Jan 10 doi: 10.1016/j.pdpdt.2024.103970. PMID: 38215957
Inflammatory linear verrucous epidermal nevus (ILVEN) encompasses a spectrum of inflammatory mosaic disorders.
Atzmony L, Ugwu N, Hamilton C, Paller AS, Zech L, Antaya RJ, Choate KA
Pediatr Dermatol 2022 Nov;39(6):903-907. Epub 2022 Jul 19 doi: 10.1111/pde.15094. PMID: 35853659Free PMC Article
Off-Label Therapeutic Potential of Crisaborole.
Makins C, Sanghera R, Grewal PS
J Cutan Med Surg 2020 May/Jun;24(3):292-296. Epub 2020 Mar 5 doi: 10.1177/1203475420909794. PMID: 32133868
Inflammatory linear verrucous epidermal nevus responsive to 308-nm excimer laser treatment.
Grgurich E, Gupta N, Owen R, Purcell SM
Cutis 2018 Aug;102(2):111-114. PMID: 30235359
Inflammatory linear verrucous epidermal nevus associated with erosive monoarthritis.
Bertolin-Colilla M, Alcalá R, Deza G, Polino L, Gallardo F, Pujol RM
Pediatr Dermatol 2018 Sep;35(5):e291-e293. Epub 2018 Jul 4 doi: 10.1111/pde.13592. PMID: 29974513

Prognosis

Development of squamous cell carcinoma on an inflammatory linear verrucous epidermal nevus in the genital area.
Turk BG, Ertam I, Urkmez A, Kazandi A, Kandiloglu G, Ozdemir F
Cutis 2012 Jun;89(6):273-5. PMID: 22838090
Carbon dioxide laser: first-line therapy in vulvar inflammatory linear verrucous epidermal nevus.
D'Antuono A, Balestri R, Zauli S, Bardazzi F, Bellavista S, Banzola N, Sgubbi P, Patrizi A
Dermatol Ther 2012 Jan-Feb;25(1):92-4. doi: 10.1111/j.1529-8019.2012.01429.x. PMID: 22591503
Does inflammatory linear verrucous epidermal nevus represent a segmental type 1/type 2 mosaic of psoriasis?
Hofer T
Dermatology 2006;212(2):103-7. doi: 10.1159/000090648. PMID: 16484814
Resurfacing CO2 laser treatment of linear verrucous epidermal nevus.
Michel JL, Has C, Has V
Eur J Dermatol 2001 Sep-Oct;11(5):436-9. PMID: 11525951
Adult onset of inflammatory linear verrucous epidermal nevus.
Kawaguchi H, Takeuchi M, Ono H, Nakajima H
J Dermatol 1999 Sep;26(9):599-602. doi: 10.1111/j.1346-8138.1999.tb02055.x. PMID: 10535255

Clinical prediction guides

Differences in clinical characteristics and lesion proteomics between inflammatory linear verrucous epidermal nevus and local verrucous epidermal nevus.
Yuan T, Lu XH, Tang B Mr, Chang XL, He CF, Wang J, Ci C
J Proteomics 2022 May 30;260:104554. Epub 2022 Mar 11 doi: 10.1016/j.jprot.2022.104554. PMID: 35283356
Inflammatory linear verrucous epidermal nevus: why a combined laser therapy.
Conti R, Bruscino N, Campolmi P, Bonan P, Cannarozzo G, Moretti S
J Cosmet Laser Ther 2013 Aug;15(4):242-5. Epub 2013 Jun 21 doi: 10.3109/14764172.2013.807115. PMID: 23692514
Inflammatory linear verrucous epidermal nevus with genital involvement.
Balci DD, Yenin JZ, Celik E, Sarikaya G, Atik E
Skinmed 2012 Mar-Apr;10(2):112-3. PMID: 22545330
Transposable elements and the lines of Blaschko: a new perspective.
Happle R
Dermatology 2002;204(1):4-7. doi: 10.1159/000051801. PMID: 11834841
Resurfacing CO2 laser treatment of linear verrucous epidermal nevus.
Michel JL, Has C, Has V
Eur J Dermatol 2001 Sep-Oct;11(5):436-9. PMID: 11525951

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...