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Flaccid dysarthria

MedGen UID:
141567
•Concept ID:
C0454597
•
Sign or Symptom
Synonyms: Dysarthria, Flaccid; Dysarthrias, Flaccid; Flaccid Dysarthria; Flaccid Dysarthrias
SNOMED CT: Flaccid dysarthria (229685007); Bulbar palsy type of dysarthria (229685007); Lower motor neurone type of dysarthria (229685007)

Professional guidelines

PubMed

Omaveloxolone: an activator of Nrf2 for the treatment of Friedreich ataxia.
Profeta V, McIntyre K, Wells M, Park C, Lynch DR
Expert Opin Investig Drugs 2023 Jan;32(1):5-16. Epub 2023 Feb 8 doi: 10.1080/13543784.2023.2173063. PMID: 36708320
Speech disorders in Parkinson's disease: pathophysiology, medical management and surgical approaches.
Dashtipour K, Tafreshi A, Lee J, Crawley B
Neurodegener Dis Manag 2018 Oct;8(5):337-348. Epub 2018 Sep 18 doi: 10.2217/nmt-2018-0021. PMID: 30223711
Contemporary Approaches to the Management of Post-stroke Apraxia of Speech.
Basilakos A
Semin Speech Lang 2018 Feb;39(1):25-36. Epub 2018 Jan 22 doi: 10.1055/s-0037-1608853. PMID: 29359303Free PMC Article

Recent clinical studies

Etiology

Acoustic Change Over Time in Spastic and/or Flaccid Dysarthria in Motor Neuron Diseases.
Lévêque N, Slis A, Lancia L, Bruneteau G, Fougeron C
J Speech Lang Hear Res 2022 May 11;65(5):1767-1783. Epub 2022 Apr 12 doi: 10.1044/2022_JSLHR-21-00434. PMID: 35412848
MuSK Myasthenia Gravis Presenting with Bilateral Vocal Cord Abduction Paresis: A Case Report and Literature Review.
Santilli A, Stitt D
Neurologist 2021 Sep 7;26(5):175-177. doi: 10.1097/NRL.0000000000000339. PMID: 34491934
Disorders of communication: dysarthria.
Enderby P
Handb Clin Neurol 2013;110:273-81. doi: 10.1016/B978-0-444-52901-5.00022-8. PMID: 23312647
Dysarthria in children with cerebellar or brainstem tumors.
van Mourik M, Catsman-Berrevoets CE, Yousef-Bak E, Paquier PF, van Dongen HR
Pediatr Neurol 1998 May;18(5):411-4. doi: 10.1016/s0887-8994(97)00232-4. PMID: 9650681
Dysphagia in elderly men with myasthenia gravis.
Kluin KJ, Bromberg MB, Feldman EL, Simmons Z
J Neurol Sci 1996 Jun;138(1-2):49-52. doi: 10.1016/0022-510x(95)00329-z. PMID: 8791238

Diagnosis

A preliminary study on self-care telemonitoring of dysarthria in spinal muscular atrophy.
Migliorelli L, Moccia S, Berardini D, Frontoni E, Coccia M, Villani L, Bandini A
Annu Int Conf IEEE Eng Med Biol Soc 2023 Jul;2023:1-4. doi: 10.1109/EMBC40787.2023.10340908. PMID: 38083694
Acoustic Change Over Time in Spastic and/or Flaccid Dysarthria in Motor Neuron Diseases.
Lévêque N, Slis A, Lancia L, Bruneteau G, Fougeron C
J Speech Lang Hear Res 2022 May 11;65(5):1767-1783. Epub 2022 Apr 12 doi: 10.1044/2022_JSLHR-21-00434. PMID: 35412848
Communication skills among children with spinal muscular atrophy type 1: A parent survey.
Ball LJ, Chavez S, Perez G, Bharucha-Goebel D, Smart K, Kundrat K, Carruthers L, Brady C, Leach M, Evans S
Assist Technol 2021 Jan 2;33(1):38-48. Epub 2019 Apr 4 doi: 10.1080/10400435.2019.1586788. PMID: 30945993
A multi-disciplinary clinic for SCN8A-related epilepsy.
Schreiber JM, Tochen L, Brown M, Evans S, Ball LJ, Bumbut A, Thewamit R, Whitehead MT, Black C, Boutzoukas E, Fanto E, Suslovic W, Berl M, Hammer M, Gaillard WD
Epilepsy Res 2020 Jan;159:106261. Epub 2019 Dec 23 doi: 10.1016/j.eplepsyres.2019.106261. PMID: 31887642
Disorders of communication: dysarthria.
Enderby P
Handb Clin Neurol 2013;110:273-81. doi: 10.1016/B978-0-444-52901-5.00022-8. PMID: 23312647

Therapy

A multi-disciplinary clinic for SCN8A-related epilepsy.
Schreiber JM, Tochen L, Brown M, Evans S, Ball LJ, Bumbut A, Thewamit R, Whitehead MT, Black C, Boutzoukas E, Fanto E, Suslovic W, Berl M, Hammer M, Gaillard WD
Epilepsy Res 2020 Jan;159:106261. Epub 2019 Dec 23 doi: 10.1016/j.eplepsyres.2019.106261. PMID: 31887642
Neurological manifestations in speech after snake bite: a rare case.
Vir D, Sachin, Gupta D, Modi M, Panda N
Pan Afr Med J 2010 Mar 24;4:13. doi: 10.4314/pamj.v4i1.53597. PMID: 21119998Free PMC Article
Warming up improves speech production in patients with adult onset myotonic dystrophy.
de Swart BJ, van Engelen BG, Maassen BA
J Commun Disord 2007 May-Jun;40(3):185-95. Epub 2006 Jul 14 doi: 10.1016/j.jcomdis.2006.06.005. PMID: 16843480

Prognosis

Neurogenic speech sequelae following suicide attempt by hanging: a case report.
Wazeer MM, John S, Rajashekhar B
Int J Adolesc Med Health 2017 Apr 1;29(2) doi: 10.1515/ijamh-2015-0039. PMID: 26360492
Semantic dementia with lower motor neuron disease showing FTLD-TDP type 3 pathology (sensu Mackenzie).
Östberg P, Bogdanović N
Neuropathology 2011 Jun;31(3):271-9. Epub 2010 Oct 5 doi: 10.1111/j.1440-1789.2010.01154.x. PMID: 21029204
Dysphagia in elderly men with myasthenia gravis.
Kluin KJ, Bromberg MB, Feldman EL, Simmons Z
J Neurol Sci 1996 Jun;138(1-2):49-52. doi: 10.1016/0022-510x(95)00329-z. PMID: 8791238
Dysarthria of motor neuron disease: longitudinal measures of segmental durations.
Seikel JA, Wilcox KA, Davis J
J Commun Disord 1991 Oct-Dec;24(5-6):393-409. doi: 10.1016/0021-9924(91)90011-7. PMID: 1809779
Dysarthria of motor neuron disease: clinician judgments of severity.
Seikel JA, Wilcox KA, Davis J
J Commun Disord 1990 Dec;23(6):417-31. doi: 10.1016/0021-9924(90)90028-w. PMID: 2286723

Clinical prediction guides

A multi-disciplinary clinic for SCN8A-related epilepsy.
Schreiber JM, Tochen L, Brown M, Evans S, Ball LJ, Bumbut A, Thewamit R, Whitehead MT, Black C, Boutzoukas E, Fanto E, Suslovic W, Berl M, Hammer M, Gaillard WD
Epilepsy Res 2020 Jan;159:106261. Epub 2019 Dec 23 doi: 10.1016/j.eplepsyres.2019.106261. PMID: 31887642
Dysarthria in children with cerebellar or brainstem tumors.
van Mourik M, Catsman-Berrevoets CE, Yousef-Bak E, Paquier PF, van Dongen HR
Pediatr Neurol 1998 May;18(5):411-4. doi: 10.1016/s0887-8994(97)00232-4. PMID: 9650681
Influence of verbal and nonverbal contexts on the sentence intelligibility of a speaker with dysarthria.
Garcia JM, Cannito MP
J Speech Hear Res 1996 Aug;39(4):750-60. doi: 10.1044/jshr.3904.750. PMID: 8844555
Dysarthria of motor neuron disease: clinician judgments of severity.
Seikel JA, Wilcox KA, Davis J
J Commun Disord 1990 Dec;23(6):417-31. doi: 10.1016/0021-9924(90)90028-w. PMID: 2286723

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