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Simple obesity

MedGen UID:
625226
•Concept ID:
C0451819
•
Disease or Syndrome
Synonym: Obesity due to excess calories
SNOMED CT: Simple obesity (415530009); Obesity due to excess calories (415530009)

Professional guidelines

PubMed

The status and childcare management of overweight and obesity among preschool children in Hangzhou.
Hu Y, Qian X, Chen J, Huang D
J Pediatr Endocrinol Metab 2023 Sep 26;36(9):859-864. Epub 2023 Aug 10 doi: 10.1515/jpem-2023-0248. PMID: 37553860
Obesity Hypoventilation Syndrome: Choosing the Appropriate Treatment of a Heterogeneous Disorder.
Piper AJ, BaHammam AS, Javaheri S
Sleep Med Clin 2017 Dec;12(4):587-596. Epub 2017 Sep 6 doi: 10.1016/j.jsmc.2017.07.008. PMID: 29108613
Acupuncture for the treatment of obesity in adults: a systematic review and meta-analysis.
Zhang RQ, Tan J, Li FY, Ma YH, Han LX, Yang XL
Postgrad Med J 2017 Dec;93(1106):743-751. Epub 2017 Jul 8 doi: 10.1136/postgradmedj-2017-134969. PMID: 28689171

Recent clinical studies

Etiology

Association between the Dietary Inflammatory Index and All-Cause Mortality in Adults with Obesity.
Zheng X, Ge YZ, Ruan GT, Lin SQ, Chen Y, Liu CA, Xie HL, Song MM, Liu T, Wang ZW, Shi JY, Zhang HY, Yang M, Liu XY, Deng L, Shi HP
Ann Nutr Metab 2023;79(5):434-447. Epub 2023 Sep 8 doi: 10.1159/000533380. PMID: 37690445
The Influence of Obesity and Metabolic Health on Vascular Health.
Rhee EJ
Endocrinol Metab (Seoul) 2022 Feb;37(1):1-8. Epub 2022 Feb 28 doi: 10.3803/EnM.2022.101. PMID: 35255597Free PMC Article
Simple obesity and renal function.
Sikorska D, Grzymislawska M, Roszak M, Gulbicka P, Korybalska K, Witowski J
J Physiol Pharmacol 2017 Apr;68(2):175-180. PMID: 28614766
Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children.
Zhang C, Yin A, Li H, Wang R, Wu G, Shen J, Zhang M, Wang L, Hou Y, Ouyang H, Zhang Y, Zheng Y, Wang J, Lv X, Wang Y, Zhang F, Zeng B, Li W, Yan F, Zhao Y, Pang X, Zhang X, Fu H, Chen F, Zhao N, Hamaker BR, Bridgewater LC, Weinkove D, Clement K, Dore J, Holmes E, Xiao H, Zhao G, Yang S, Bork P, Nicholson JK, Wei H, Tang H, Zhang X, Zhao L
EBioMedicine 2015 Aug;2(8):968-84. Epub 2015 Jul 10 doi: 10.1016/j.ebiom.2015.07.007. PMID: 26425705Free PMC Article
Overgrowth.
Verge CF, Mowat D
Arch Dis Child 2010 Jun;95(6):458-63. Epub 2010 Apr 6 doi: 10.1136/adc.2009.157693. PMID: 20371592

Diagnosis

Overweight and obesity in children and adolescents with endocrine disorders.
Pomahacova R, Paterova P, Nykodymova E, Polak P, Sladkova E, Skalicka E, Sykora J
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2023 Dec;167(4):328-334. Epub 2023 Sep 4 doi: 10.5507/bp.2023.036. PMID: 37712247
The status and childcare management of overweight and obesity among preschool children in Hangzhou.
Hu Y, Qian X, Chen J, Huang D
J Pediatr Endocrinol Metab 2023 Sep 26;36(9):859-864. Epub 2023 Aug 10 doi: 10.1515/jpem-2023-0248. PMID: 37553860
Simple obesity and renal function.
Sikorska D, Grzymislawska M, Roszak M, Gulbicka P, Korybalska K, Witowski J
J Physiol Pharmacol 2017 Apr;68(2):175-180. PMID: 28614766
Harmful effects of functional hypercortisolism: a working hypothesis.
Tirabassi G, Boscaro M, Arnaldi G
Endocrine 2014 Aug;46(3):370-86. Epub 2013 Nov 27 doi: 10.1007/s12020-013-0112-y. PMID: 24282037
Overgrowth.
Verge CF, Mowat D
Arch Dis Child 2010 Jun;95(6):458-63. Epub 2010 Apr 6 doi: 10.1136/adc.2009.157693. PMID: 20371592

Therapy

Clinical efficacy of weight loss herbal intervention therapy and lifestyle modifications on obesity and its association with distinct gut microbiome: A randomized double-blind phase 2 study.
Cao MZ, Wei CH, Wen MC, Song Y, Srivastava K, Yang N, Shi YM, Miao M, Chung D, Li XM
Front Endocrinol (Lausanne) 2023;14:1054674. Epub 2023 Mar 22 doi: 10.3389/fendo.2023.1054674. PMID: 37033234Free PMC Article
Efficacy of acupuncture and moxibustion therapy for simple obesity in adults: A meta-analysis of randomized controlled trials.
Yin Y, Zhao Q, Li S, Jiang H, Yin C, Chen H, Zhang Y
Medicine (Baltimore) 2022 Oct 28;101(43):e31148. doi: 10.1097/MD.0000000000031148. PMID: 36316908Free PMC Article
Tuina combined with diet and exercise for simple obesity: A protocol for systematic review.
Chen L, Cong D, Wang G, Sun J, Ji Y, Zhong Z, Liu T, Liu J, Chu Y, Wu X
Medicine (Baltimore) 2022 Feb 11;101(6):e28833. doi: 10.1097/MD.0000000000028833. PMID: 35147126Free PMC Article
Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children.
Zhang C, Yin A, Li H, Wang R, Wu G, Shen J, Zhang M, Wang L, Hou Y, Ouyang H, Zhang Y, Zheng Y, Wang J, Lv X, Wang Y, Zhang F, Zeng B, Li W, Yan F, Zhao Y, Pang X, Zhang X, Fu H, Chen F, Zhao N, Hamaker BR, Bridgewater LC, Weinkove D, Clement K, Dore J, Holmes E, Xiao H, Zhao G, Yang S, Bork P, Nicholson JK, Wei H, Tang H, Zhang X, Zhao L
EBioMedicine 2015 Aug;2(8):968-84. Epub 2015 Jul 10 doi: 10.1016/j.ebiom.2015.07.007. PMID: 26425705Free PMC Article
Pharmacotherapy of obesity.
Finer N
Best Pract Res Clin Endocrinol Metab 2002 Dec;16(4):717-42. doi: 10.1053/beem.2002.0231. PMID: 12468417

Prognosis

The status and childcare management of overweight and obesity among preschool children in Hangzhou.
Hu Y, Qian X, Chen J, Huang D
J Pediatr Endocrinol Metab 2023 Sep 26;36(9):859-864. Epub 2023 Aug 10 doi: 10.1515/jpem-2023-0248. PMID: 37553860
Gut Microbiota Characteristics of People with Obesity by Meta-Analysis of Existing Datasets.
Gong J, Shen Y, Zhang H, Cao M, Guo M, He J, Zhang B, Xiao C
Nutrients 2022 Jul 21;14(14) doi: 10.3390/nu14142993. PMID: 35889949Free PMC Article
Key pathway and gene alterations in the gastric mucosa associated with obesity and obesity-related diabetes.
Wen X, Qian C, Zhang Y, Wu R, Lu L, Zhu C, Cheng X, Cui R, You H, Mei F, Gao J, Li F, Bu L, Qu S
J Cell Biochem 2019 Apr;120(4):6763-6771. Epub 2018 Nov 18 doi: 10.1002/jcb.27976. PMID: 30450618
Comparable Enhanced Prothrombogenesis in Simple Central Obesity and Metabolic Syndrome.
Mohd Nor NS, Saimin H, Rahman T, Abdul Razak S, Mohd Nasir N, Ismail Z, Mohd Nawawi H
J Obes 2018;2018:8508549. Epub 2018 Mar 26 doi: 10.1155/2018/8508549. PMID: 29785305Free PMC Article
Simple obesity and renal function.
Sikorska D, Grzymislawska M, Roszak M, Gulbicka P, Korybalska K, Witowski J
J Physiol Pharmacol 2017 Apr;68(2):175-180. PMID: 28614766

Clinical prediction guides

The status and childcare management of overweight and obesity among preschool children in Hangzhou.
Hu Y, Qian X, Chen J, Huang D
J Pediatr Endocrinol Metab 2023 Sep 26;36(9):859-864. Epub 2023 Aug 10 doi: 10.1515/jpem-2023-0248. PMID: 37553860
Distinct Lipids Profiles and Associations With Clinical Indicators and Gut Microbiota in Children With Prader-Willi Syndrome.
Hou Y, Deng F, Guo J, Lv L, Ouyang H, Wang X, Luo Y, Chen X, Wang F
Endocrinology 2023 Jun 6;164(7) doi: 10.1210/endocr/bqad084. PMID: 37232361
Autoimmune reaction against pancreatic beta cells in children and adolescents with simple obesity.
Chylińska-Frątczak A, Pietrzak I, Michalak A, Wyka K, Szadkowska A
Front Endocrinol (Lausanne) 2022;13:1061671. Epub 2022 Dec 14 doi: 10.3389/fendo.2022.1061671. PMID: 36589801Free PMC Article
Association between inflammatory markers and non-alcoholic fatty liver disease in obese children.
Duan Y, Luo J, Pan X, Wei J, Xiao X, Li J, Luo M
Front Public Health 2022;10:991393. Epub 2022 Dec 1 doi: 10.3389/fpubh.2022.991393. PMID: 36530698Free PMC Article
Clinical characteristics and risk factors of nonalcoholic fatty liver disease in children with obesity.
Peng L, Wu S, Zhou N, Zhu S, Liu Q, Li X
BMC Pediatr 2021 Mar 12;21(1):122. doi: 10.1186/s12887-021-02595-2. PMID: 33711964Free PMC Article

Recent systematic reviews

Effects of electroacupuncture on obesity: A systematic review and meta-analysis.
Kang J, Shin WC, Kim KW, Kim S, Kim H, Cho JH, Song MY, Chung WS
Medicine (Baltimore) 2024 Jan 12;103(2):e36774. doi: 10.1097/MD.0000000000036774. PMID: 38215111Free PMC Article
Comparative Effectiveness of East Asian Traditional Medicine for Childhood Simple Obesity: A Systematic Review and Network Meta-Analysis.
Lee B, Kwon CY
Int J Environ Res Public Health 2022 Oct 11;19(20) doi: 10.3390/ijerph192012994. PMID: 36293575Free PMC Article
Massage for simple obesity: A protocol for systematic review.
Pang Y, Wang K, Chen S, Huang T, Zhang M, Zhang B, Yu J
Medicine (Baltimore) 2021 Feb 12;100(6):e24336. doi: 10.1097/MD.0000000000024336. PMID: 33578528Free PMC Article
Acupuncture versus sham acupuncture for simple obesity: a systematic review and meta-analysis.
Zhong YM, Luo XC, Chen Y, Lai DL, Lu WT, Shang YN, Zhang LL, Zhou HY
Postgrad Med J 2020 Apr;96(1134):221-227. Epub 2020 Feb 3 doi: 10.1136/postgradmedj-2019-137221. PMID: 32015189Free PMC Article
Acupuncture for the treatment of obesity in adults: a systematic review and meta-analysis.
Zhang RQ, Tan J, Li FY, Ma YH, Han LX, Yang XL
Postgrad Med J 2017 Dec;93(1106):743-751. Epub 2017 Jul 8 doi: 10.1136/postgradmedj-2017-134969. PMID: 28689171

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