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Osteoarthritis of the first carpometacarpal joint

MedGen UID:
488890
•Concept ID:
C0409956
•
Disease or Syndrome
Synonyms: Osteoarthritis basilar joint of thumb; Osteoarthritis of first carpometacarpal joint; Osteoarthrosis of the carpometacarpal joint of the thumb
SNOMED CT: Osteoarthritis basilar joint of thumb (37895003); Osteoarthritis of first carpometacarpal joint (37895003); Osteoarthrosis of the carpometacarpal joint of the thumb (37895003)
 
HPO: HP:0006226

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOsteoarthritis of the first carpometacarpal joint

Conditions with this feature

Osteoarthritis susceptibility 3
MedGen UID:
382650
•Concept ID:
C2675609
•
Finding
Any osteoarthritis in which the cause of the disease is a mutation in the ASPN gene.
See: Condition Record
Osteoarthritis susceptibility 3

Professional guidelines

PubMed

Diagnosis and Treatment of Carpometacarpal Instability.
Warwick D, Fetouh S
Hand Clin 2022 May;38(2):261-268. doi: 10.1016/j.hcl.2021.11.005. PMID: 35465943
2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee.
Kolasinski SL, Neogi T, Hochberg MC, Oatis C, Guyatt G, Block J, Callahan L, Copenhaver C, Dodge C, Felson D, Gellar K, Harvey WF, Hawker G, Herzig E, Kwoh CK, Nelson AE, Samuels J, Scanzello C, White D, Wise B, Altman RD, DiRenzo D, Fontanarosa J, Giradi G, Ishimori M, Misra D, Shah AA, Shmagel AK, Thoma LM, Turgunbaev M, Turner AS, Reston J
Arthritis Rheumatol 2020 Feb;72(2):220-233. Epub 2020 Jan 6 doi: 10.1002/art.41142. PMID: 31908163Free PMC Article
2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee.
Kolasinski SL, Neogi T, Hochberg MC, Oatis C, Guyatt G, Block J, Callahan L, Copenhaver C, Dodge C, Felson D, Gellar K, Harvey WF, Hawker G, Herzig E, Kwoh CK, Nelson AE, Samuels J, Scanzello C, White D, Wise B, Altman RD, DiRenzo D, Fontanarosa J, Giradi G, Ishimori M, Misra D, Shah AA, Shmagel AK, Thoma LM, Turgunbaev M, Turner AS, Reston J
Arthritis Care Res (Hoboken) 2020 Feb;72(2):149-162. Epub 2020 Jan 6 doi: 10.1002/acr.24131. PMID: 31908149Free PMC Article

Recent clinical studies

Etiology

Long-Term Outcomes of Nonsurgical Treatment of Thumb Carpometacarpal Osteoarthritis: A Cohort Study.
Esteban Lopez LMJ, Hoogendam L, Vermeulen GM, Tsehaie J, Slijper HP, Selles RW, Wouters RM; The Hand-Wrist Study Group
J Bone Joint Surg Am 2023 Dec 6;105(23):1837-1845. Epub 2023 Oct 30 doi: 10.2106/JBJS.22.01116. PMID: 37903291Free PMC Article
Bone morphological changes of the trapezium and first metacarpal with early thumb osteoarthritis progression.
Morton AM, Peipert LJ, Moore DC, Ladd AL, Weiss AC, Molino J, Crisco JJ
Clin Biomech (Bristol, Avon) 2022 Dec;100:105791. Epub 2022 Oct 5 doi: 10.1016/j.clinbiomech.2022.105791. PMID: 36228419Free PMC Article
Familial Clustering and Genetic Analysis of Severe Thumb Carpometacarpal Joint Osteoarthritis in a Large Statewide Cohort.
Gavile CM, Kazmers NH, Novak KA, Meeks HD, Yu Z, Thomas JL, Hansen C, Barker T, Jurynec MJ
J Hand Surg Am 2022 Oct;47(10):923-933. Epub 2022 Sep 29 doi: 10.1016/j.jhsa.2022.08.004. PMID: 36184273Free PMC Article
First Carpometacarpal Joint Denervation: A Systematic Review.
Rezzadeh K, Rossi K, Trerotola CC, Shah A
J Hand Surg Am 2022 Aug;47(8):793.e1-793.e8. Epub 2021 Sep 8 doi: 10.1016/j.jhsa.2021.07.020. PMID: 34509313
Surgery for trapeziometacarpal osteoarthritis.
Gay AM, Cerlier A, Iniesta A, Legré R
Hand Surg Rehabil 2016 Sep;35(4):238-249. Epub 2016 Jul 21 doi: 10.1016/j.hansur.2016.06.002. PMID: 27781986

Diagnosis

Relationships between diagnostic imaging of first carpometacarpal osteoarthritis and pain, functional status, and disease progression: A systematic review.
Mazza DF, Boonsri PS, Arora A, Bayne CO, Szabo RM, Chaudhari AJ, Boutin RD
Osteoarthritis Cartilage 2024 May;32(5):476-492. Epub 2023 Dec 21 doi: 10.1016/j.joca.2023.11.023. PMID: 38141842
Diagnosis and Treatment of Carpometacarpal Instability.
Warwick D, Fetouh S
Hand Clin 2022 May;38(2):261-268. doi: 10.1016/j.hcl.2021.11.005. PMID: 35465943
Nonpharmacological and nonsurgical approaches in OA.
Bierma-Zeinstra S, van Middelkoop M, Runhaar J, Schiphof D
Best Pract Res Clin Rheumatol 2020 Apr;34(2):101564. Epub 2020 Aug 6 doi: 10.1016/j.berh.2020.101564. PMID: 32773214
2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee.
Kolasinski SL, Neogi T, Hochberg MC, Oatis C, Guyatt G, Block J, Callahan L, Copenhaver C, Dodge C, Felson D, Gellar K, Harvey WF, Hawker G, Herzig E, Kwoh CK, Nelson AE, Samuels J, Scanzello C, White D, Wise B, Altman RD, DiRenzo D, Fontanarosa J, Giradi G, Ishimori M, Misra D, Shah AA, Shmagel AK, Thoma LM, Turgunbaev M, Turner AS, Reston J
Arthritis Care Res (Hoboken) 2020 Feb;72(2):149-162. Epub 2020 Jan 6 doi: 10.1002/acr.24131. PMID: 31908149Free PMC Article
Imaging and management of thumb carpometacarpal joint osteoarthritis.
Melville DM, Taljanovic MS, Scalcione LR, Eble JM, Gimber LH, DeSilva GL, Sheppard JE
Skeletal Radiol 2015 Feb;44(2):165-77. Epub 2014 Sep 11 doi: 10.1007/s00256-014-1997-0. PMID: 25209021

Therapy

Denervation as a Treatment for Arthritis of the Hands: A Systematic Review of the Current Literature.
Zhu SL, Chin B, Sarraj M, Wang E, Dunn EE, McRae MC
Hand (N Y) 2023 Mar;18(2):183-191. Epub 2021 Mar 1 doi: 10.1177/1558944721994251. PMID: 33648375Free PMC Article
Trapeziectomy versus joint replacement for first carpometacarpal (CMC 1) joint osteoarthritis: a systematic review and meta-analysis.
Raj S, Clay R, Ramji S, Shaunak R, Dadrewalla A, Sinha V, Shaunak S
Eur J Orthop Surg Traumatol 2022 Aug;32(6):1001-1021. Epub 2021 Jul 9 doi: 10.1007/s00590-021-03070-5. PMID: 34244850Free PMC Article
2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee.
Kolasinski SL, Neogi T, Hochberg MC, Oatis C, Guyatt G, Block J, Callahan L, Copenhaver C, Dodge C, Felson D, Gellar K, Harvey WF, Hawker G, Herzig E, Kwoh CK, Nelson AE, Samuels J, Scanzello C, White D, Wise B, Altman RD, DiRenzo D, Fontanarosa J, Giradi G, Ishimori M, Misra D, Shah AA, Shmagel AK, Thoma LM, Turgunbaev M, Turner AS, Reston J
Arthritis Care Res (Hoboken) 2020 Feb;72(2):149-162. Epub 2020 Jan 6 doi: 10.1002/acr.24131. PMID: 31908149Free PMC Article
First Carpometacarpal Joint Denervation for Primary Osteoarthritis: Technique and Outcomes.
Donato D, Abunimer AM, Abou-Al-Shaar H, Willcockson J, Frazer L, Mahan MA
World Neurosurg 2019 Feb;122:e1374-e1380. Epub 2018 Nov 19 doi: 10.1016/j.wneu.2018.11.061. PMID: 30465956
Proliferative injection therapy for osteoarthritis: a systematic review.
Krstičević M, Jerić M, Došenović S, Jeličić Kadić A, Puljak L
Int Orthop 2017 Apr;41(4):671-679. Epub 2017 Feb 11 doi: 10.1007/s00264-017-3422-5. PMID: 28190092

Prognosis

Relationships between diagnostic imaging of first carpometacarpal osteoarthritis and pain, functional status, and disease progression: A systematic review.
Mazza DF, Boonsri PS, Arora A, Bayne CO, Szabo RM, Chaudhari AJ, Boutin RD
Osteoarthritis Cartilage 2024 May;32(5):476-492. Epub 2023 Dec 21 doi: 10.1016/j.joca.2023.11.023. PMID: 38141842
Long-Term Outcomes of Nonsurgical Treatment of Thumb Carpometacarpal Osteoarthritis: A Cohort Study.
Esteban Lopez LMJ, Hoogendam L, Vermeulen GM, Tsehaie J, Slijper HP, Selles RW, Wouters RM; The Hand-Wrist Study Group
J Bone Joint Surg Am 2023 Dec 6;105(23):1837-1845. Epub 2023 Oct 30 doi: 10.2106/JBJS.22.01116. PMID: 37903291Free PMC Article
Dorsal Subluxation of the First Metacarpal During Thumb Flexion is an Indicator of Carpometacarpal Osteoarthritis Progression.
Morton AM, Moore DC, Ladd AL, Weiss AC, Molino J, Crisco JJ
Clin Orthop Relat Res 2023 Jun 1;481(6):1224-1237. Epub 2023 Mar 6 doi: 10.1097/CORR.0000000000002575. PMID: 36877171Free PMC Article
Pyrocardan® implant after failed trapeziectomy.
Pouedras M, Chaves C, Gaisne E, Ardouin L, Bellemère P
Hand Surg Rehabil 2021 Feb;40(1):51-56. Epub 2020 Sep 19 doi: 10.1016/j.hansur.2020.09.005. PMID: 32961290
Nonpharmacological and nonsurgical approaches in OA.
Bierma-Zeinstra S, van Middelkoop M, Runhaar J, Schiphof D
Best Pract Res Clin Rheumatol 2020 Apr;34(2):101564. Epub 2020 Aug 6 doi: 10.1016/j.berh.2020.101564. PMID: 32773214

Clinical prediction guides

Relationships between diagnostic imaging of first carpometacarpal osteoarthritis and pain, functional status, and disease progression: A systematic review.
Mazza DF, Boonsri PS, Arora A, Bayne CO, Szabo RM, Chaudhari AJ, Boutin RD
Osteoarthritis Cartilage 2024 May;32(5):476-492. Epub 2023 Dec 21 doi: 10.1016/j.joca.2023.11.023. PMID: 38141842
Long-Term Outcomes of Nonsurgical Treatment of Thumb Carpometacarpal Osteoarthritis: A Cohort Study.
Esteban Lopez LMJ, Hoogendam L, Vermeulen GM, Tsehaie J, Slijper HP, Selles RW, Wouters RM; The Hand-Wrist Study Group
J Bone Joint Surg Am 2023 Dec 6;105(23):1837-1845. Epub 2023 Oct 30 doi: 10.2106/JBJS.22.01116. PMID: 37903291Free PMC Article
Familial Clustering and Genetic Analysis of Severe Thumb Carpometacarpal Joint Osteoarthritis in a Large Statewide Cohort.
Gavile CM, Kazmers NH, Novak KA, Meeks HD, Yu Z, Thomas JL, Hansen C, Barker T, Jurynec MJ
J Hand Surg Am 2022 Oct;47(10):923-933. Epub 2022 Sep 29 doi: 10.1016/j.jhsa.2022.08.004. PMID: 36184273Free PMC Article
Concurrent validity and precision of the thumb disability examination (TDX) in first carpometacarpal osteoarthritis.
Johnson L, Karau R, McGee C
J Hand Ther 2022 Jul-Sep;35(3):428-434. Epub 2021 Sep 23 doi: 10.1016/j.jht.2021.07.002. PMID: 34563444Free PMC Article
First Carpometacarpal Joint Denervation: A Systematic Review.
Rezzadeh K, Rossi K, Trerotola CC, Shah A
J Hand Surg Am 2022 Aug;47(8):793.e1-793.e8. Epub 2021 Sep 8 doi: 10.1016/j.jhsa.2021.07.020. PMID: 34509313

Recent systematic reviews

Relationships between diagnostic imaging of first carpometacarpal osteoarthritis and pain, functional status, and disease progression: A systematic review.
Mazza DF, Boonsri PS, Arora A, Bayne CO, Szabo RM, Chaudhari AJ, Boutin RD
Osteoarthritis Cartilage 2024 May;32(5):476-492. Epub 2023 Dec 21 doi: 10.1016/j.joca.2023.11.023. PMID: 38141842
Arthrodesis for Carpometacarpal Joint Arthritis: A Systematic Review.
Dharamsi MS, Caudle K, Fares A, Dunn J
Hand (N Y) 2023 Nov;18(8):1284-1290. Epub 2022 Jul 6 doi: 10.1177/15589447221105541. PMID: 35794840Free PMC Article
First Carpometacarpal Joint Denervation: A Systematic Review.
Rezzadeh K, Rossi K, Trerotola CC, Shah A
J Hand Surg Am 2022 Aug;47(8):793.e1-793.e8. Epub 2021 Sep 8 doi: 10.1016/j.jhsa.2021.07.020. PMID: 34509313
Systematic Review of Thumb Carpometacarpal Joint Hemiresection Interposition Arthroplasty Materials.
Spiteri M, Giele H
Hand (N Y) 2022 Sep;17(5):809-814. Epub 2020 Dec 14 doi: 10.1177/1558944720974124. PMID: 33307813Free PMC Article
Proliferative injection therapy for osteoarthritis: a systematic review.
Krstičević M, Jerić M, Došenović S, Jeličić Kadić A, Puljak L
Int Orthop 2017 Apr;41(4):671-679. Epub 2017 Feb 11 doi: 10.1007/s00264-017-3422-5. PMID: 28190092

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