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Adynamic bone disease

MedGen UID:
588482
Concept ID:
C0403566
Disease or Syndrome
Synonym: Aplastic bone disease
SNOMED CT: Aplastic bone disease (236552002); Adynamic bone disease (236552002)

Professional guidelines

PubMed

Ginsberg C, Ix JH
Am J Kidney Dis 2022 Mar;79(3):427-436. Epub 2021 Aug 20 doi: 10.1053/j.ajkd.2021.06.031. PMID: 34419519
Haarhaus M, Evenepoel P; European Renal Osteodystrophy (EUROD) workgroup; Chronic Kidney Disease Mineral and Bone Disorder (CKD-MBD) working group of the European Renal Association–European Dialysis and Transplant Association (ERA-EDTA)
Kidney Int 2021 Sep;100(3):546-558. Epub 2021 Jun 5 doi: 10.1016/j.kint.2021.04.043. PMID: 34102219
Delos Santos R, Rossi A, Coyne D, Maw TT
Drugs 2019 Apr;79(5):501-513. doi: 10.1007/s40265-019-01074-4. PMID: 30811012Free PMC Article

Recent clinical studies

Etiology

Sharma S, Gupta A
Nefrologia (Engl Ed) 2022 Jan-Feb;42(1):8-14. doi: 10.1016/j.nefroe.2022.03.005. PMID: 36153902
Ginsberg C, Ix JH
Am J Kidney Dis 2022 Mar;79(3):427-436. Epub 2021 Aug 20 doi: 10.1053/j.ajkd.2021.06.031. PMID: 34419519
Hsu CY, Chen LR, Chen KH
Int J Mol Sci 2020 Sep 18;21(18) doi: 10.3390/ijms21186846. PMID: 32961953Free PMC Article
Bover J, Ureña P, Brandenburg V, Goldsmith D, Ruiz C, DaSilva I, Bosch RJ
Semin Nephrol 2014 Nov;34(6):626-40. doi: 10.1016/j.semnephrol.2014.09.008. PMID: 25498381
Frazão JM, Martins P
Curr Opin Nephrol Hypertens 2009 Jul;18(4):303-7. doi: 10.1097/MNH.0b013e32832c4df0. PMID: 19424062

Diagnosis

Ginsberg C, Ix JH
Am J Kidney Dis 2022 Mar;79(3):427-436. Epub 2021 Aug 20 doi: 10.1053/j.ajkd.2021.06.031. PMID: 34419519
Torregrosa JV, Ferreira AC, Cucchiari D, Ferreira A
Calcif Tissue Int 2021 Apr;108(4):551-560. Epub 2021 Mar 25 doi: 10.1007/s00223-021-00837-0. PMID: 33765230
Bover J, Ureña P, Brandenburg V, Goldsmith D, Ruiz C, DaSilva I, Bosch RJ
Semin Nephrol 2014 Nov;34(6):626-40. doi: 10.1016/j.semnephrol.2014.09.008. PMID: 25498381
Frazão JM, Martins P
Curr Opin Nephrol Hypertens 2009 Jul;18(4):303-7. doi: 10.1097/MNH.0b013e32832c4df0. PMID: 19424062
Mucsi I, Hercz G
Am J Med Sci 1999 Jun;317(6):405-9. doi: 10.1097/00000441-199906000-00009. PMID: 10372841

Therapy

Torregrosa JV, Ferreira AC, Cucchiari D, Ferreira A
Calcif Tissue Int 2021 Apr;108(4):551-560. Epub 2021 Mar 25 doi: 10.1007/s00223-021-00837-0. PMID: 33765230
Hsu CY, Chen LR, Chen KH
Int J Mol Sci 2020 Sep 18;21(18) doi: 10.3390/ijms21186846. PMID: 32961953Free PMC Article
Jeon HJ, Kim H, Yang J
Curr Opin Endocrinol Diabetes Obes 2015 Dec;22(6):452-8. doi: 10.1097/MED.0000000000000196. PMID: 26512770
Frazão JM, Martins P
Curr Opin Nephrol Hypertens 2009 Jul;18(4):303-7. doi: 10.1097/MNH.0b013e32832c4df0. PMID: 19424062
Mucsi I, Hercz G
Curr Opin Nephrol Hypertens 1997 Jul;6(4):356-61. doi: 10.1097/00041552-199707000-00008. PMID: 9263684

Prognosis

Haarhaus M, Evenepoel P; European Renal Osteodystrophy (EUROD) workgroup; Chronic Kidney Disease Mineral and Bone Disorder (CKD-MBD) working group of the European Renal Association–European Dialysis and Transplant Association (ERA-EDTA)
Kidney Int 2021 Sep;100(3):546-558. Epub 2021 Jun 5 doi: 10.1016/j.kint.2021.04.043. PMID: 34102219
Hsu CY, Chen LR, Chen KH
Int J Mol Sci 2020 Sep 18;21(18) doi: 10.3390/ijms21186846. PMID: 32961953Free PMC Article
Bover J, Ureña-Torres P, Torregrosa JV, Rodríguez-García M, Castro-Alonso C, Górriz JL, Laiz Alonso AM, Cigarrán S, Benito S, López-Báez V, Lloret Cora MJ, daSilva I, Cannata-Andía J
Nefrologia (Engl Ed) 2018 Sep-Oct;38(5):476-490. Epub 2018 Apr 24 doi: 10.1016/j.nefro.2017.12.006. PMID: 29703451
Massy Z, Drueke T
J Nephrol 2017 Oct;30(5):629-634. Epub 2017 Apr 12 doi: 10.1007/s40620-017-0397-7. PMID: 28405928
Frazão JM, Martins P
Curr Opin Nephrol Hypertens 2009 Jul;18(4):303-7. doi: 10.1097/MNH.0b013e32832c4df0. PMID: 19424062

Clinical prediction guides

Haarhaus M, Evenepoel P; European Renal Osteodystrophy (EUROD) workgroup; Chronic Kidney Disease Mineral and Bone Disorder (CKD-MBD) working group of the European Renal Association–European Dialysis and Transplant Association (ERA-EDTA)
Kidney Int 2021 Sep;100(3):546-558. Epub 2021 Jun 5 doi: 10.1016/j.kint.2021.04.043. PMID: 34102219
Bover J, Ureña-Torres P, Torregrosa JV, Rodríguez-García M, Castro-Alonso C, Górriz JL, Laiz Alonso AM, Cigarrán S, Benito S, López-Báez V, Lloret Cora MJ, daSilva I, Cannata-Andía J
Nefrologia (Engl Ed) 2018 Sep-Oct;38(5):476-490. Epub 2018 Apr 24 doi: 10.1016/j.nefro.2017.12.006. PMID: 29703451
Massy Z, Drueke T
J Nephrol 2017 Oct;30(5):629-634. Epub 2017 Apr 12 doi: 10.1007/s40620-017-0397-7. PMID: 28405928
Bover J, Ureña P, Brandenburg V, Goldsmith D, Ruiz C, DaSilva I, Bosch RJ
Semin Nephrol 2014 Nov;34(6):626-40. doi: 10.1016/j.semnephrol.2014.09.008. PMID: 25498381
Frazão JM, Martins P
Curr Opin Nephrol Hypertens 2009 Jul;18(4):303-7. doi: 10.1097/MNH.0b013e32832c4df0. PMID: 19424062

Recent systematic reviews

Hsu CY, Chen LR, Chen KH
Int J Mol Sci 2020 Sep 18;21(18) doi: 10.3390/ijms21186846. PMID: 32961953Free PMC Article
Liu ME, Qiu NC, Zha SL, Du ZP, Wang YF, Wang Q, Chen Q, Cen XX, Jiang Y, Luo Q, Shan CX, Qiu M
Int J Surg 2017 Aug;44:353-362. Epub 2017 Jun 17 doi: 10.1016/j.ijsu.2017.06.029. PMID: 28634117
Strippoli GF, Tong A, Palmer SC, Elder G, Craig JC
Cochrane Database Syst Rev 2006 Oct 18;(4):CD006254. doi: 10.1002/14651858.CD006254. PMID: 17054287

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