U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Distal intestinal obstruction syndrome

MedGen UID:
97978
•Concept ID:
C0398349
•
Disease or Syndrome
Synonyms: DIOS - Distal intestinal obstruction syndrome; Meconium ileus equivalent; MIE - Meconium ileus equivalent
SNOMED CT: Distal intestinal obstruction syndrome (233662009); DIOS - Distal intestinal obstruction syndrome (233662009); Meconium ileus equivalent (233662009); MIE - Meconium ileus equivalent (233662009)

Professional guidelines

PubMed

Constipation and DIOS: Diagnosis, differential diagnosis, and management.
Saikumar P, Sadauskas M, Izhar S, Moshiree B, Patel D
Pediatr Pulmonol 2024 Sep;59 Suppl 1:S81-S90. doi: 10.1002/ppul.27104. PMID: 39105354
Distal intestinal obstruction syndrome: an important differential diagnosis for abdominal pain in patients with cystic fibrosis.
Hort A, Hameed A, Middleton PG, Pleass HC
ANZ J Surg 2020 May;90(5):681-686. Epub 2019 Jul 30 doi: 10.1111/ans.15357. PMID: 31364217
Guidelines for the diagnosis and management of distal intestinal obstruction syndrome in cystic fibrosis patients.
Colombo C, Ellemunter H, Houwen R, Munck A, Taylor C, Wilschanski M; ECFS
J Cyst Fibros 2011 Jun;10 Suppl 2:S24-8. doi: 10.1016/S1569-1993(11)60005-2. PMID: 21658638

Recent clinical studies

Etiology

Digestive outcomes in Cystic fibrosis.
Ley D, Turck D
Best Pract Res Clin Gastroenterol 2022 Feb-Mar;56-57:101788. Epub 2022 Feb 24 doi: 10.1016/j.bpg.2022.101788. PMID: 35331400
Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Gilchrist FJ, Green J, Carroll W
Cochrane Database Syst Rev 2021 Dec 22;12(12):CD012798. doi: 10.1002/14651858.CD012798.pub3. PMID: 34936086Free PMC Article
Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Carroll W, Green J, Gilchrist FJ
Cochrane Database Syst Rev 2021 Dec 22;12(12):CD012619. doi: 10.1002/14651858.CD012619.pub3. PMID: 34936085Free PMC Article
Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Green J, Carroll W, Gilchrist FJ
Cochrane Database Syst Rev 2018 Aug 3;8(8):CD012798. doi: 10.1002/14651858.CD012798.pub2. PMID: 30075058Free PMC Article
Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Green J, Gilchrist FJ, Carroll W
Cochrane Database Syst Rev 2018 Jun 12;6(6):CD012619. doi: 10.1002/14651858.CD012619.pub2. PMID: 29894558Free PMC Article

Diagnosis

Constipation and DIOS: Diagnosis, differential diagnosis, and management.
Saikumar P, Sadauskas M, Izhar S, Moshiree B, Patel D
Pediatr Pulmonol 2024 Sep;59 Suppl 1:S81-S90. doi: 10.1002/ppul.27104. PMID: 39105354
Meconium Ileus, Distal Intestinal Obstruction Syndrome, and Other Gastrointestinal Pathology in the Cystic Fibrosis Patient.
Tobias J, Tillotson M, Maloney L, Fialkowski E
Surg Clin North Am 2022 Oct;102(5):873-882. Epub 2022 Sep 7 doi: 10.1016/j.suc.2022.07.016. PMID: 36209752
Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Gilchrist FJ, Green J, Carroll W
Cochrane Database Syst Rev 2021 Dec 22;12(12):CD012798. doi: 10.1002/14651858.CD012798.pub3. PMID: 34936086Free PMC Article
Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Green J, Carroll W, Gilchrist FJ
Cochrane Database Syst Rev 2018 Aug 3;8(8):CD012798. doi: 10.1002/14651858.CD012798.pub2. PMID: 30075058Free PMC Article
Distal intestinal obstruction syndrome and colonic pathologies in cystic fibrosis.
Canny JD, Brookes A, Bowley DB
Br J Hosp Med (Lond) 2017 Jan 2;78(1):38-43. doi: 10.12968/hmed.2017.78.1.38. PMID: 28067560

Therapy

Cystic Fibrosis Modulator Therapies.
Jia S, Taylor-Cousar JL
Annu Rev Med 2023 Jan 27;74:413-426. Epub 2022 Aug 16 doi: 10.1146/annurev-med-042921-021447. PMID: 35973718
Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Gilchrist FJ, Green J, Carroll W
Cochrane Database Syst Rev 2021 Dec 22;12(12):CD012798. doi: 10.1002/14651858.CD012798.pub3. PMID: 34936086Free PMC Article
Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Carroll W, Green J, Gilchrist FJ
Cochrane Database Syst Rev 2021 Dec 22;12(12):CD012619. doi: 10.1002/14651858.CD012619.pub3. PMID: 34936085Free PMC Article
Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Green J, Carroll W, Gilchrist FJ
Cochrane Database Syst Rev 2018 Aug 3;8(8):CD012798. doi: 10.1002/14651858.CD012798.pub2. PMID: 30075058Free PMC Article
Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Green J, Gilchrist FJ, Carroll W
Cochrane Database Syst Rev 2018 Jun 12;6(6):CD012619. doi: 10.1002/14651858.CD012619.pub2. PMID: 29894558Free PMC Article

Prognosis

Cystic fibrosis and fat malabsorption: Pathophysiology of the cystic fibrosis gastrointestinal tract and the impact of highly effective CFTR modulator therapy.
McDonald CM, Reid EK, Pohl JF, Yuzyuk TK, Padula LM, Vavrina K, Altman K
Nutr Clin Pract 2024 Apr;39 Suppl 1:S57-S77. doi: 10.1002/ncp.11122. PMID: 38429959
Cystic Fibrosis Modulator Therapies.
Jia S, Taylor-Cousar JL
Annu Rev Med 2023 Jan 27;74:413-426. Epub 2022 Aug 16 doi: 10.1146/annurev-med-042921-021447. PMID: 35973718
Digestive outcomes in Cystic fibrosis.
Ley D, Turck D
Best Pract Res Clin Gastroenterol 2022 Feb-Mar;56-57:101788. Epub 2022 Feb 24 doi: 10.1016/j.bpg.2022.101788. PMID: 35331400
High ambient temperature and risk of intestinal obstruction in cystic fibrosis.
Ooi CY, Jeyaruban C, Lau J, Katz T, Matson A, Bell SC, Adams SE, Krishnan U
J Paediatr Child Health 2016 Apr;52(4):430-5. doi: 10.1111/jpc.13096. PMID: 27145507
Beyond pancreatic insufficiency and liver disease in cystic fibrosis.
Demeyer S, De Boeck K, Witters P, Cosaert K
Eur J Pediatr 2016 Jul;175(7):881-94. Epub 2016 Apr 7 doi: 10.1007/s00431-016-2719-5. PMID: 27055450

Clinical prediction guides

Digestive outcomes in Cystic fibrosis.
Ley D, Turck D
Best Pract Res Clin Gastroenterol 2022 Feb-Mar;56-57:101788. Epub 2022 Feb 24 doi: 10.1016/j.bpg.2022.101788. PMID: 35331400
Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Carroll W, Green J, Gilchrist FJ
Cochrane Database Syst Rev 2021 Dec 22;12(12):CD012619. doi: 10.1002/14651858.CD012619.pub3. PMID: 34936085Free PMC Article
Distal intestinal obstruction syndrome: a diagnostic and therapeutic challenge in cystic fibrosis.
Sandy NS, Massabki LHP, Gonçalves AC, Ribeiro AF, Ribeiro JD, Servidoni MFCP, Lomazi EA
J Pediatr (Rio J) 2020 Nov-Dec;96(6):732-740. Epub 2019 Oct 22 doi: 10.1016/j.jped.2019.08.009. PMID: 31654616Free PMC Article
Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Green J, Gilchrist FJ, Carroll W
Cochrane Database Syst Rev 2018 Jun 12;6(6):CD012619. doi: 10.1002/14651858.CD012619.pub2. PMID: 29894558Free PMC Article
Lung transplantation in cystic fibrosis.
Rosenblatt RL
Respir Care 2009 Jun;54(6):777-86; discussion 786-7. doi: 10.4187/002013209790983197. PMID: 19467164

Recent systematic reviews

Thinking outside the box: a review of gastrointestinal symptoms and complications in cystic fibrosis.
Yule A, Sills D, Smith S, Spiller R, Smyth AR
Expert Rev Respir Med 2023 Jul-Dec;17(7):547-561. Epub 2023 Jun 26 doi: 10.1080/17476348.2023.2228194. PMID: 37345513
Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Gilchrist FJ, Green J, Carroll W
Cochrane Database Syst Rev 2021 Dec 22;12(12):CD012798. doi: 10.1002/14651858.CD012798.pub3. PMID: 34936086Free PMC Article
Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Carroll W, Green J, Gilchrist FJ
Cochrane Database Syst Rev 2021 Dec 22;12(12):CD012619. doi: 10.1002/14651858.CD012619.pub3. PMID: 34936085Free PMC Article
Interventions for treating distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Green J, Carroll W, Gilchrist FJ
Cochrane Database Syst Rev 2018 Aug 3;8(8):CD012798. doi: 10.1002/14651858.CD012798.pub2. PMID: 30075058Free PMC Article
Interventions for preventing distal intestinal obstruction syndrome (DIOS) in cystic fibrosis.
Green J, Gilchrist FJ, Carroll W
Cochrane Database Syst Rev 2018 Jun 12;6(6):CD012619. doi: 10.1002/14651858.CD012619.pub2. PMID: 29894558Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...