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Headache associated with sexual activity(HSA)

MedGen UID:
95989
Concept ID:
C0393754
Sign or Symptom
Synonyms: BENIGN SEXUAL HEADACHE; HSA
SNOMED CT: Headache associated with sexual activity (103010005)
 
Monarch Initiative: MONDO:0011848
OMIM®: 607504

Definition

The Headache Classification Committee of the International Headache Society (1988) classified headache associated with sexual activity (HSA) as an idiopathic headache under 'miscellaneous headaches unassociated with structural lesions.' Based on initial descriptions, 3 subtypes are differentiated: type 1 is a dull ache in the head and neck that slowly intensifies as sexual excitement increases, and is believed to be caused by muscle contraction similar to tension-type headache; type 2, also called 'vascular-type,' is a sudden severe, explosive headache occurring at orgasm, which may be due to increased intracranial pressure; type 3, the most uncommon type, is a postural headache resembling that caused by decreased CSF pressure, perhaps due to a meningeal tear during coitus (summary by Frese et al., 2003). [from OMIM]

Professional guidelines

PubMed

Smith JH
Continuum (Minneap Minn) 2021 Jun 1;27(3):652-664. doi: 10.1212/CON.0000000000000960. PMID: 34048397
Mitsikostas DD, Ashina M, Craven A, Diener HC, Goadsby PJ, Ferrari MD, Lampl C, Paemeleire K, Pascual J, Siva A, Olesen J, Osipova V, Martelletti P; EHF committee
J Headache Pain 2015;17:5. Epub 2016 Feb 9 doi: 10.1186/s10194-016-0596-y. PMID: 26857820Free PMC Article
Frese A, Rahmann A, Gregor N, Biehl K, Husstedt IW, Evers S
Cephalalgia 2007 Nov;27(11):1265-70. Epub 2007 Oct 5 doi: 10.1111/j.1468-2982.2007.01449.x. PMID: 17919305

Recent clinical studies

Etiology

Lin PT, Wang YF, Fuh JL, Lirng JF, Ling YH, Chen SP, Wang SJ
Cephalalgia 2021 Dec;41(14):1447-1457. Epub 2021 Jul 18 doi: 10.1177/03331024211028965. PMID: 34275353
Smith JH
Continuum (Minneap Minn) 2021 Jun 1;27(3):652-664. doi: 10.1212/CON.0000000000000960. PMID: 34048397
Linn FH
Handb Clin Neurol 2010;97:473-81. doi: 10.1016/S0072-9752(10)97042-5. PMID: 20816448
De Luca GC, Bartleson JD
Semin Neurol 2010 Apr;30(2):131-44. Epub 2010 Mar 29 doi: 10.1055/s-0030-1249221. PMID: 20352583
Pascual J
Neurol Clin 2009 May;27(2):557-71. doi: 10.1016/j.ncl.2009.01.005. PMID: 19289232

Diagnosis

Nandyala A, Zhang N
Curr Pain Headache Rep 2023 Nov;27(11):679-684. Epub 2023 Sep 25 doi: 10.1007/s11916-023-01171-w. PMID: 37747622
Ściślicki P, Sztuba K, Klimkowicz-Mrowiec A, Gorzkowska A
Medicina (Kaunas) 2021 Jul 21;57(8) doi: 10.3390/medicina57080735. PMID: 34440941Free PMC Article
Lin PT, Wang YF, Fuh JL, Lirng JF, Ling YH, Chen SP, Wang SJ
Cephalalgia 2021 Dec;41(14):1447-1457. Epub 2021 Jul 18 doi: 10.1177/03331024211028965. PMID: 34275353
Smith JH
Continuum (Minneap Minn) 2021 Jun 1;27(3):652-664. doi: 10.1212/CON.0000000000000960. PMID: 34048397
Starling AJ
Continuum (Minneap Minn) 2018 Aug;24(4, Headache):1192-1208. doi: 10.1212/CON.0000000000000636. PMID: 30074556

Therapy

Maynard P, Pace A
Curr Pain Headache Rep 2024 Jul;28(7):627-632. Epub 2024 Feb 17 doi: 10.1007/s11916-023-01206-2. PMID: 38367200
Makarevičius G, Ryliškienė K
Cephalalgia 2022 Jun;42(7):680-683. Epub 2022 Feb 15 doi: 10.1177/03331024221075074. PMID: 35166159Free PMC Article
Smith JH
Continuum (Minneap Minn) 2021 Jun 1;27(3):652-664. doi: 10.1212/CON.0000000000000960. PMID: 34048397
Özcan T, Yancar Demir E, İşcanlı MD
Agri 2017 Apr;29(2):79-81. doi: 10.5505/agri.2015.24654. PMID: 28895983
Halker RB, Vargas BB
Curr Pain Headache Rep 2013 Jun;17(6):337. doi: 10.1007/s11916-013-0337-8. PMID: 23606018

Prognosis

Lin PT, Chen SP, Wang SJ
Cephalalgia 2023 Mar;43(3):3331024221148657. doi: 10.1177/03331024221148657. PMID: 36786380
Lin PT, Wang YF, Fuh JL, Lirng JF, Ling YH, Chen SP, Wang SJ
Cephalalgia 2021 Dec;41(14):1447-1457. Epub 2021 Jul 18 doi: 10.1177/03331024211028965. PMID: 34275353
Smith JH
Continuum (Minneap Minn) 2021 Jun 1;27(3):652-664. doi: 10.1212/CON.0000000000000960. PMID: 34048397
Csépány É, Tóth M, Gyüre T, Magyar M, Bozsik G, Bereczki D, Juhász G, Ertsey C
J Headache Pain 2018 Nov 12;19(1):106. doi: 10.1186/s10194-018-0938-z. PMID: 30419813Free PMC Article
Frese A, Rahmann A, Gregor N, Biehl K, Husstedt IW, Evers S
Cephalalgia 2007 Nov;27(11):1265-70. Epub 2007 Oct 5 doi: 10.1111/j.1468-2982.2007.01449.x. PMID: 17919305

Clinical prediction guides

Nandyala A, Zhang N
Curr Pain Headache Rep 2023 Nov;27(11):679-684. Epub 2023 Sep 25 doi: 10.1007/s11916-023-01171-w. PMID: 37747622
Lin PT, Wang YF, Fuh JL, Lirng JF, Ling YH, Chen SP, Wang SJ
Cephalalgia 2021 Dec;41(14):1447-1457. Epub 2021 Jul 18 doi: 10.1177/03331024211028965. PMID: 34275353
Smith JH
Continuum (Minneap Minn) 2021 Jun 1;27(3):652-664. doi: 10.1212/CON.0000000000000960. PMID: 34048397
Ari BC, Mayda Domac F, Ulutas S
J Clin Neurosci 2020 Sep;79:51-53. Epub 2020 Aug 4 doi: 10.1016/j.jocn.2020.07.068. PMID: 33070917
Csépány É, Tóth M, Gyüre T, Magyar M, Bozsik G, Bereczki D, Juhász G, Ertsey C
J Headache Pain 2018 Nov 12;19(1):106. doi: 10.1186/s10194-018-0938-z. PMID: 30419813Free PMC Article

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