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Hyperuricemia without signs of inflammatory arthritis and tophaceous disease

MedGen UID:
578547
•Concept ID:
C0348944
•
Disease or Syndrome
Synonym: Asymptomatic hyperuricemia
SNOMED CT: Hyperuricemia without signs of inflammatory arthritis and tophaceous disease (190920002); Asymptomatic hyperuricemia (190920002)

Professional guidelines

PubMed

Gout - An update of aetiology, genetics, co-morbidities and management.
Robinson PC
Maturitas 2018 Dec;118:67-73. Epub 2018 Oct 26 doi: 10.1016/j.maturitas.2018.10.012. PMID: 30415758
Treatment of hyperuricemia, gout and other crystalline arthritidies.
Lioté F
Reumatismo 2012 Jan 19;63(4):276-83. doi: 10.4081/reumatismo.2011.276. PMID: 22303534
Clinical utility of dual-energy CT for evaluation of tophaceous gout.
Desai MA, Peterson JJ, Garner HW, Kransdorf MJ
Radiographics 2011 Sep-Oct;31(5):1365-75; discussion 1376-7. doi: 10.1148/rg.315115510. PMID: 21918049

Recent clinical studies

Etiology

Managing hyperuricemia and gout in chronic kidney disease: a clinical conundrum.
Premachandra KH, Day RO, Roberts DM
Curr Opin Nephrol Hypertens 2021 Mar 1;30(2):245-251. doi: 10.1097/MNH.0000000000000691. PMID: 33399392
Chronic gout in the elderly.
Bolzetta F, Veronese N, Manzato E, Sergi G
Aging Clin Exp Res 2013 May;25(2):129-37. Epub 2013 Apr 9 doi: 10.1007/s40520-013-0031-z. PMID: 23739897
The last defence? Surgical aspects of gouty arthritis of hand and wrist.
Tang CY, Fung B
Hong Kong Med J 2011 Dec;17(6):480-6. PMID: 22147319
Axial gouty arthropathy.
Saketkoo LA, Robertson HJ, Dyer HR, Virk ZU, Ferreyro HR, Espinoza LR
Am J Med Sci 2009 Aug;338(2):140-6. doi: 10.1097/MAJ.0b013e3181a3dc14. PMID: 19680018
Updates in the management of gout.
Keith MP, Gilliland WR
Am J Med 2007 Mar;120(3):221-4. doi: 10.1016/j.amjmed.2006.02.044. PMID: 17349440

Diagnosis

Imaging of gout: findings and pitfalls. A pictorial review.
Sudoł-Szopińska I, Afonso PD, Jacobson JA, Teh J
Acta Reumatol Port 2020 Jan-Mar;45(1):20-25. PMID: 32572014
Axial (spinal) gout.
Lumezanu E, Konatalapalli R, Weinstein A
Curr Rheumatol Rep 2012 Apr;14(2):161-4. doi: 10.1007/s11926-012-0236-8. PMID: 22318623
Axial gouty arthropathy.
Saketkoo LA, Robertson HJ, Dyer HR, Virk ZU, Ferreyro HR, Espinoza LR
Am J Med Sci 2009 Aug;338(2):140-6. doi: 10.1097/MAJ.0b013e3181a3dc14. PMID: 19680018
Gout and hyperuricemia.
Harris MD, Siegel LB, Alloway JA
Am Fam Physician 1999 Feb 15;59(4):925-34. PMID: 10068714
Crystals and arthritis.
McCarty DJ
Dis Mon 1994 Jun;40(6):255-99. doi: 10.1016/0011-5029(94)90021-3. PMID: 8194428

Therapy

Managing hyperuricemia and gout in chronic kidney disease: a clinical conundrum.
Premachandra KH, Day RO, Roberts DM
Curr Opin Nephrol Hypertens 2021 Mar 1;30(2):245-251. doi: 10.1097/MNH.0000000000000691. PMID: 33399392
Ulcerated tophaceous gout.
Filanovsky MG, Sukhdeo K, McNamara MC
BMJ Case Rep 2015 Aug 3;2015 doi: 10.1136/bcr-2015-210707. PMID: 26240104Free PMC Article
Chronic gout in the elderly.
Bolzetta F, Veronese N, Manzato E, Sergi G
Aging Clin Exp Res 2013 May;25(2):129-37. Epub 2013 Apr 9 doi: 10.1007/s40520-013-0031-z. PMID: 23739897
Treatment of hyperuricemia, gout and other crystalline arthritidies.
Lioté F
Reumatismo 2012 Jan 19;63(4):276-83. doi: 10.4081/reumatismo.2011.276. PMID: 22303534
Updates in the management of gout.
Keith MP, Gilliland WR
Am J Med 2007 Mar;120(3):221-4. doi: 10.1016/j.amjmed.2006.02.044. PMID: 17349440

Prognosis

Simple metabolic markers associated with tophaceous gout.
Liu W, Song H, Man S, Li H, Gao S
Clin Rheumatol 2021 Dec;40(12):5047-5053. Epub 2021 Jul 15 doi: 10.1007/s10067-021-05861-x. PMID: 34264406
Ulcerated tophaceous gout.
Filanovsky MG, Sukhdeo K, McNamara MC
BMJ Case Rep 2015 Aug 3;2015 doi: 10.1136/bcr-2015-210707. PMID: 26240104Free PMC Article
Joint effects of alcohol consumption and ABCG2 Q141K on chronic tophaceous gout risk.
Tu HP, Ko AM, Chiang SL, Lee SS, Lai HM, Chung CM, Huang CM, Lee CH, Kuo TM, Hsieh MJ, Ko YC
J Rheumatol 2014 Apr;41(4):749-58. Epub 2014 Feb 15 doi: 10.3899/jrheum.130870. PMID: 24532835
Mechanisms of joint damage in gout: evidence from cellular and imaging studies.
McQueen FM, Chhana A, Dalbeth N
Nat Rev Rheumatol 2012 Jan 10;8(3):173-81. doi: 10.1038/nrrheum.2011.207. PMID: 22231231
Updates in the management of gout.
Keith MP, Gilliland WR
Am J Med 2007 Mar;120(3):221-4. doi: 10.1016/j.amjmed.2006.02.044. PMID: 17349440

Clinical prediction guides

Simple metabolic markers associated with tophaceous gout.
Liu W, Song H, Man S, Li H, Gao S
Clin Rheumatol 2021 Dec;40(12):5047-5053. Epub 2021 Jul 15 doi: 10.1007/s10067-021-05861-x. PMID: 34264406
Entheseal involvement of the lower extremities in gout: an ultrasonographic descriptive observational study.
Xu G, Lin J, Liang J, Yang Y, Ye Z, Zhu G, Cao H
Clin Rheumatol 2021 Nov;40(11):4649-4657. Epub 2021 Jun 22 doi: 10.1007/s10067-021-05826-0. PMID: 34156566
A cross-sectional study of 502 patients found a diffuse hyperechoic kidney medulla pattern in patients with severe gout.
Bardin T, Nguyen QD, Tran KM, Le NH, Do MD, Richette P, Letavernier E, Correas JM, Resche-Rigon M
Kidney Int 2021 Jan;99(1):218-226. Epub 2020 Sep 6 doi: 10.1016/j.kint.2020.08.024. PMID: 32898570
Assessment of cardiovascular risk profile based on measurement of tophus volume in patients with gout.
Lee KA, Ryu SR, Park SJ, Kim HR, Lee SH
Clin Rheumatol 2018 May;37(5):1351-1358. Epub 2017 Dec 29 doi: 10.1007/s10067-017-3963-4. PMID: 29288369
Joint effects of alcohol consumption and ABCG2 Q141K on chronic tophaceous gout risk.
Tu HP, Ko AM, Chiang SL, Lee SS, Lai HM, Chung CM, Huang CM, Lee CH, Kuo TM, Hsieh MJ, Ko YC
J Rheumatol 2014 Apr;41(4):749-58. Epub 2014 Feb 15 doi: 10.3899/jrheum.130870. PMID: 24532835

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