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Ovarian embryonal carcinoma

MedGen UID:
91090
•Concept ID:
C0346183
•
Neoplastic Process
Synonyms: embryonal carcinoma; Embryonal carcinoma of ovary; Embryonal Carcinoma of Ovary; embryonal carcinoma of ovary; Embryonal Carcinoma of the Ovary; embryonal carcinoma of the ovary; Ovarian Embryonal Carcinoma; ovarian embryonal carcinoma; ovary embryonal carcinoma
SNOMED CT: Embryonal carcinoma of ovary (254872007)
 
Monarch Initiative: MONDO:0003581

Definition

An embryonal carcinoma arising from the ovary. Signs and symptoms include the presence of an abdominal mass and abdominal pain. [from NCI]

Professional guidelines

PubMed

ESGO-SIOPE guidelines for the management of adolescents and young adults with non-epithelial ovarian cancers.
Sessa C, Schneider DT, Planchamp F, Baust K, Braicu EI, Concin N, Godzinski J, McCluggage WG, Orbach D, Pautier P, Peccatori FA, Morice P, Calaminus G
Lancet Oncol 2020 Jul;21(7):e360-e368. doi: 10.1016/S1470-2045(20)30091-7. PMID: 32615119
Epigenetic Pathways Offer Targets for Ovarian Cancer Treatment.
Gyparaki MT, Papavassiliou AG
Clin Breast Cancer 2018 Jun;18(3):189-191. Epub 2017 Sep 19 doi: 10.1016/j.clbc.2017.09.009. PMID: 29042129
Evaluation and management of pediatric solid ovarian tumors.
Lazar EL, Stolar CJ
Semin Pediatr Surg 1998 Feb;7(1):29-34. doi: 10.1016/s1055-8586(98)70003-4. PMID: 9498265

Recent clinical studies

Etiology

Imaging in gynecological disease (22): clinical and ultrasound characteristics of ovarian embryonal carcinomas, non-gestational choriocarcinomas and malignant mixed germ cell tumors.
Moro F, Castellano LM, Franchi D, Epstein E, Fischerova D, Froyman W, Timmerman D, Zannoni GF, Scambia G, Valentin L, Testa AC, Mascilini F
Ultrasound Obstet Gynecol 2021 Jun;57(6):987-994. doi: 10.1002/uog.23529. PMID: 33142349

Diagnosis

Imaging in gynecological disease (22): clinical and ultrasound characteristics of ovarian embryonal carcinomas, non-gestational choriocarcinomas and malignant mixed germ cell tumors.
Moro F, Castellano LM, Franchi D, Epstein E, Fischerova D, Froyman W, Timmerman D, Zannoni GF, Scambia G, Valentin L, Testa AC, Mascilini F
Ultrasound Obstet Gynecol 2021 Jun;57(6):987-994. doi: 10.1002/uog.23529. PMID: 33142349
Morphologic, immunohistochemical, and fluorescence in situ hybridization study of ovarian embryonal carcinoma with comparison to solid variant of yolk sac tumor and immature teratoma.
Cheng L, Zhang S, Talerman A, Roth LM
Hum Pathol 2010 May;41(5):716-23. Epub 2010 Jan 21 doi: 10.1016/j.humpath.2009.10.016. PMID: 20096442
Familial clustering of malignant germ cell tumors and Langerhans' histiocytosis.
Mandel M, Toren A, Kende G, Neuman Y, Kenet G, Rechavi G
Cancer 1994 Apr 1;73(7):1980-3. doi: 10.1002/1097-0142(19940401)73:7<1980::aid-cncr2820730732>3.0.co;2-9. PMID: 8137225

Therapy

Alpha-fetoprotein and human chorionic gonadotropin in embryonal carcinoma of the ovary. An 8-year survival case.
Nakakuma K, Tashiro S, Uemura K, Takayama K
Cancer 1983 Oct 15;52(8):1470-2. doi: 10.1002/1097-0142(19831015)52:8<1470::aid-cncr2820520822>3.0.co;2-#. PMID: 6193860

Prognosis

Morphologic, immunohistochemical, and fluorescence in situ hybridization study of ovarian embryonal carcinoma with comparison to solid variant of yolk sac tumor and immature teratoma.
Cheng L, Zhang S, Talerman A, Roth LM
Hum Pathol 2010 May;41(5):716-23. Epub 2010 Jan 21 doi: 10.1016/j.humpath.2009.10.016. PMID: 20096442

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