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Multiple ventricular septal defects

MedGen UID:
576624
•Concept ID:
C0344923
•
Congenital Abnormality
SNOMED CT: Multiple ventricular septal defects (253550006)

Professional guidelines

PubMed

A review of the therapeutic management of multiple ventricular septal defects.
Chowdhury UK, Anderson RH, Spicer DE, Sankhyan LK, George N, Pandey NN, Balaji A, Goja S, Malik V
J Card Surg 2022 May;37(5):1361-1376. Epub 2022 Feb 11 doi: 10.1111/jocs.16289. PMID: 35146802
Management of infants with large, unrepaired ventricular septal defects and respiratory infection requiring mechanical ventilation.
Bhatt M, Roth SJ, Kumar RK, Gauvreau K, Nair SG, Chengode S, Shivaprakasha K, Rao SG
J Thorac Cardiovasc Surg 2004 May;127(5):1466-73. doi: 10.1016/j.jtcvs.2003.11.030. PMID: 15116009

Recent clinical studies

Etiology

Association of Myocardial Muscle Non-Compaction and Multiple Ventricular Septal Defects by Echocardiography.
AlFadley F, Abdelbaky N, Alhabdan M, Issa Z, Yansaneh A, Al-Hassnan ZN, Albert-Brotons DC
Pediatr Cardiol 2022 Aug;43(6):1373-1378. Epub 2022 Mar 7 doi: 10.1007/s00246-022-02861-9. PMID: 35257196
A reassessment of the anatomical features of multiple ventricular septal defects.
Spicer DE, Anderson RH, Chowdhury UK, Sankhyan LK, George N, Pandey NN, Gupta SK, Goja S
J Card Surg 2022 May;37(5):1353-1360. Epub 2022 Feb 11 doi: 10.1111/jocs.16242. PMID: 35146794
Twinning and major birth defects, National Birth Defects Prevention Study, 1997-2007.
Dawson AL, Tinker SC, Jamieson DJ, Hobbs CA, Berry RJ, Rasmussen SA, Anderka M, Keppler-Noreuil KM, Lin AE, Reefhuis J; National Birth Defects Prevention Study
J Epidemiol Community Health 2016 Nov;70(11):1114-1121. Epub 2016 Jun 20 doi: 10.1136/jech-2015-206302. PMID: 27325867Free PMC Article
Ventricular septal dysfunction after surgical closure of multiple ventricular septal defects.
Matsuhisa H, Yoshimura N, Higuma T, Misaki T, Onuma Y, Ichida F, Oshima Y, Okita Y
Ann Thorac Surg 2013 Sep;96(3):891-7. Epub 2013 Jul 26 doi: 10.1016/j.athoracsur.2013.05.013. PMID: 23895887
Tel Hashomer camptodactyly syndrome: 12-year follow-up of a Hungarian patient and review.
Melegh B, Hollódy K, Aszmann M, Méhes K
Am J Med Genet A 2005 Jun 15;135(3):320-3. doi: 10.1002/ajmg.a.30736. PMID: 15887272

Diagnosis

Association of Myocardial Muscle Non-Compaction and Multiple Ventricular Septal Defects by Echocardiography.
AlFadley F, Abdelbaky N, Alhabdan M, Issa Z, Yansaneh A, Al-Hassnan ZN, Albert-Brotons DC
Pediatr Cardiol 2022 Aug;43(6):1373-1378. Epub 2022 Mar 7 doi: 10.1007/s00246-022-02861-9. PMID: 35257196
A review of the therapeutic management of multiple ventricular septal defects.
Chowdhury UK, Anderson RH, Spicer DE, Sankhyan LK, George N, Pandey NN, Balaji A, Goja S, Malik V
J Card Surg 2022 May;37(5):1361-1376. Epub 2022 Feb 11 doi: 10.1111/jocs.16289. PMID: 35146802
De Novo interstitial deletion 13q33.3q34 in a male patient with double outlet right ventricle, microcephaly, dysmorphic craniofacial findings, and motor and developmental delay.
McMahon CJ, Breathnach C, Betts DR, Sharkey FH, Greally MT
Am J Med Genet A 2015 May;167A(5):1134-41. Epub 2015 Mar 21 doi: 10.1002/ajmg.a.36978. PMID: 25810372
Open-heart surgery in an infant with heterozygous factor VII deficiency.
Matsuhisa H, Yoshimura N, Niimi H, Ichida F
Interact Cardiovasc Thorac Surg 2010 Jun;10(6):1037-8. Epub 2010 Mar 2 doi: 10.1510/icvts.2009.228569. PMID: 20197348
Tel Hashomer camptodactyly syndrome: 12-year follow-up of a Hungarian patient and review.
Melegh B, Hollódy K, Aszmann M, Méhes K
Am J Med Genet A 2005 Jun 15;135(3):320-3. doi: 10.1002/ajmg.a.30736. PMID: 15887272

Therapy

Outcomes of Patients Undergoing Surgical Management of Multiple Ventricular Septal Defects.
Daley M, Brizard CP, Konstantinov IE, Brink J, Kelly A, Jones B, Zannino D, d'Udekem Y
Semin Thorac Cardiovasc Surg 2019 Spring;31(1):89-96. Epub 2018 Mar 27 doi: 10.1053/j.semtcvs.2018.03.006. PMID: 29601908
Ventricular septal dysfunction after surgical closure of multiple ventricular septal defects.
Matsuhisa H, Yoshimura N, Higuma T, Misaki T, Onuma Y, Ichida F, Oshima Y, Okita Y
Ann Thorac Surg 2013 Sep;96(3):891-7. Epub 2013 Jul 26 doi: 10.1016/j.athoracsur.2013.05.013. PMID: 23895887
Long-term complications following surgical patch closure of multiple muscular ventricular septal defects.
Hofmeyr L, Pohlner P, Radford DJ
Congenit Heart Dis 2013 Nov-Dec;8(6):541-9. Epub 2013 Jan 28 doi: 10.1111/chd.12038. PMID: 23350905
Open-heart surgery in an infant with heterozygous factor VII deficiency.
Matsuhisa H, Yoshimura N, Niimi H, Ichida F
Interact Cardiovasc Thorac Surg 2010 Jun;10(6):1037-8. Epub 2010 Mar 2 doi: 10.1510/icvts.2009.228569. PMID: 20197348
Management of infants with large, unrepaired ventricular septal defects and respiratory infection requiring mechanical ventilation.
Bhatt M, Roth SJ, Kumar RK, Gauvreau K, Nair SG, Chengode S, Shivaprakasha K, Rao SG
J Thorac Cardiovasc Surg 2004 May;127(5):1466-73. doi: 10.1016/j.jtcvs.2003.11.030. PMID: 15116009

Prognosis

A reassessment of the anatomical features of multiple ventricular septal defects.
Spicer DE, Anderson RH, Chowdhury UK, Sankhyan LK, George N, Pandey NN, Gupta SK, Goja S
J Card Surg 2022 May;37(5):1353-1360. Epub 2022 Feb 11 doi: 10.1111/jocs.16242. PMID: 35146794
A Simple Technique for Closing Multiple Muscular and Apical Ventricular Septal Defects.
Talwar S, Bhoje A, Airan B
J Card Surg 2015 Sep;30(9):731-4. Epub 2015 Jun 28 doi: 10.1111/jocs.12590. PMID: 26118439
Ventricular septal dysfunction after surgical closure of multiple ventricular septal defects.
Matsuhisa H, Yoshimura N, Higuma T, Misaki T, Onuma Y, Ichida F, Oshima Y, Okita Y
Ann Thorac Surg 2013 Sep;96(3):891-7. Epub 2013 Jul 26 doi: 10.1016/j.athoracsur.2013.05.013. PMID: 23895887
Tel Hashomer camptodactyly syndrome: 12-year follow-up of a Hungarian patient and review.
Melegh B, Hollódy K, Aszmann M, Méhes K
Am J Med Genet A 2005 Jun 15;135(3):320-3. doi: 10.1002/ajmg.a.30736. PMID: 15887272
Tetralogy of Fallot.
McNicholas KW, Malm JR
Cardiovasc Clin 1981;11(2):323-36. PMID: 6163537

Clinical prediction guides

Association of Myocardial Muscle Non-Compaction and Multiple Ventricular Septal Defects by Echocardiography.
AlFadley F, Abdelbaky N, Alhabdan M, Issa Z, Yansaneh A, Al-Hassnan ZN, Albert-Brotons DC
Pediatr Cardiol 2022 Aug;43(6):1373-1378. Epub 2022 Mar 7 doi: 10.1007/s00246-022-02861-9. PMID: 35257196
A reassessment of the anatomical features of multiple ventricular septal defects.
Spicer DE, Anderson RH, Chowdhury UK, Sankhyan LK, George N, Pandey NN, Gupta SK, Goja S
J Card Surg 2022 May;37(5):1353-1360. Epub 2022 Feb 11 doi: 10.1111/jocs.16242. PMID: 35146794
Twinning and major birth defects, National Birth Defects Prevention Study, 1997-2007.
Dawson AL, Tinker SC, Jamieson DJ, Hobbs CA, Berry RJ, Rasmussen SA, Anderka M, Keppler-Noreuil KM, Lin AE, Reefhuis J; National Birth Defects Prevention Study
J Epidemiol Community Health 2016 Nov;70(11):1114-1121. Epub 2016 Jun 20 doi: 10.1136/jech-2015-206302. PMID: 27325867Free PMC Article
Ventricular septal dysfunction after surgical closure of multiple ventricular septal defects.
Matsuhisa H, Yoshimura N, Higuma T, Misaki T, Onuma Y, Ichida F, Oshima Y, Okita Y
Ann Thorac Surg 2013 Sep;96(3):891-7. Epub 2013 Jul 26 doi: 10.1016/j.athoracsur.2013.05.013. PMID: 23895887
Tetralogy of Fallot.
McNicholas KW, Malm JR
Cardiovasc Clin 1981;11(2):323-36. PMID: 6163537

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