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Acute HIV infection

MedGen UID:
575808
•Concept ID:
C0343752
•
Disease or Syndrome
Synonyms: Acute human immunodeficiency virus infection; Acute human immunodeficiency virus seroconversion illness
SNOMED CT: Acute HIV infection (111880001); Acute human immunodeficiency virus seroconversion illness (111880001); Acute human immunodeficiency virus infection (111880001)

Professional guidelines

PubMed

Cognitive trajectories after treatment in acute HIV infection.
Chan P, Kerr SJ, Kroon E, Colby D, Sacdalan C, Hellmuth J, Reiss P, Vasan S, Ananworanich J, Valcour V, Spudich S, Paul R; RV254/SEARCH 010 Research Team
AIDS 2021 May 1;35(6):883-888. doi: 10.1097/QAD.0000000000002831. PMID: 33534200
Challenges of HIV diagnosis and management in the context of pre-exposure prophylaxis (PrEP), post-exposure prophylaxis (PEP), test and start and acute HIV infection: a scoping review.
Elliott T, Sanders EJ, Doherty M, Ndung'u T, Cohen M, Patel P, Cairns G, Rutstein SE, Ananworanich J, Brown C, Fidler S
J Int AIDS Soc 2019 Dec;22(12):e25419. doi: 10.1002/jia2.25419. PMID: 31850686Free PMC Article
The pharmacological treatment of acute HIV infections in neonates.
Kuhn L, Shiau S
Expert Rev Clin Pharmacol 2017 Dec;10(12):1353-1361. Epub 2017 Nov 3 doi: 10.1080/17512433.2017.1398645. PMID: 29098898Free PMC Article

Recent clinical studies

Therapy

Challenges of HIV diagnosis and management in the context of pre-exposure prophylaxis (PrEP), post-exposure prophylaxis (PEP), test and start and acute HIV infection: a scoping review.
Elliott T, Sanders EJ, Doherty M, Ndung'u T, Cohen M, Patel P, Cairns G, Rutstein SE, Ananworanich J, Brown C, Fidler S
J Int AIDS Soc 2019 Dec;22(12):e25419. doi: 10.1002/jia2.25419. PMID: 31850686Free PMC Article
HIV Preexposure Prophylaxis: A Review.
Riddell J 4th, Amico KR, Mayer KH
JAMA 2018 Mar 27;319(12):1261-1268. doi: 10.1001/jama.2018.1917. PMID: 29584848
Human Immunodeficiency Virus.
Armstrong WS, Guarner J, Kraft CS, Caliendo AM
Microbiol Spectr 2016 Aug;4(4) doi: 10.1128/microbiolspec.DMIH2-0024-2015. PMID: 27726785
Lessons from acute HIV infection.
Robb ML, Ananworanich J
Curr Opin HIV AIDS 2016 Nov;11(6):555-560. doi: 10.1097/COH.0000000000000316. PMID: 27716734Free PMC Article
What is new in HIV infection?
Sherin K, Klekamp BG, Beal J, Martin N
Am Fam Physician 2014 Feb 15;89(4):265-72. PMID: 24695446

Prognosis

HIV-1 Persistence and Chronic Induction of Innate Immune Responses in Macrophages.
Akiyama H, Gummuluru S
Viruses 2020 Jun 30;12(7) doi: 10.3390/v12070711. PMID: 32630058Free PMC Article
Lessons from acute HIV infection.
Robb ML, Ananworanich J
Curr Opin HIV AIDS 2016 Nov;11(6):555-560. doi: 10.1097/COH.0000000000000316. PMID: 27716734Free PMC Article
Programmatic Implications of Acute and Early HIV Infection.
Suthar AB, Granich RM, Kato M, Nsanzimana S, Montaner JS, Williams BG
J Infect Dis 2015 Nov 1;212(9):1351-60. Epub 2015 Aug 26 doi: 10.1093/infdis/jiv430. PMID: 26310309
Diagnosis and management of acute HIV infection.
Zetola NM, Pilcher CD
Infect Dis Clin North Am 2007 Mar;21(1):19-48, vii. doi: 10.1016/j.idc.2007.01.008. PMID: 17502228
Recognising acute HIV infection.
Anderson J
Aust Fam Physician 2003 May;32(5):317-21. PMID: 12772361

Clinical prediction guides

Clinical and laboratory impact of concomitant syphilis infection during acute HIV.
Chan P, Colby DJ, Kroon E, Sacdalan C, Pinyakorn S, Paul R, Robb M, Valcour V, Ananworanich J, Marra C, Spudich S
HIV Med 2021 Jul;22(6):502-511. Epub 2021 Mar 17 doi: 10.1111/hiv.13079. PMID: 33728759
Cognitive trajectories after treatment in acute HIV infection.
Chan P, Kerr SJ, Kroon E, Colby D, Sacdalan C, Hellmuth J, Reiss P, Vasan S, Ananworanich J, Valcour V, Spudich S, Paul R; RV254/SEARCH 010 Research Team
AIDS 2021 May 1;35(6):883-888. doi: 10.1097/QAD.0000000000002831. PMID: 33534200
Is reaching 90-90-90 enough to end AIDS? Lessons from Amsterdam.
de Bree GJ, van Sighem A, Zuilhof W, van Bergen JEAM, Prins M, Heidenrijk M, van der Valk M, Brokx P, Reiss P; HIV Transmission Elimination AMsterdam (H-TEAM) Initiative
Curr Opin HIV AIDS 2019 Nov;14(6):455-463. doi: 10.1097/COH.0000000000000586. PMID: 31589173
HIV Preexposure Prophylaxis: A Review.
Riddell J 4th, Amico KR, Mayer KH
JAMA 2018 Mar 27;319(12):1261-1268. doi: 10.1001/jama.2018.1917. PMID: 29584848
Lessons from acute HIV infection.
Robb ML, Ananworanich J
Curr Opin HIV AIDS 2016 Nov;11(6):555-560. doi: 10.1097/COH.0000000000000316. PMID: 27716734Free PMC Article

Recent systematic reviews

Barriers and facilitators to uptake and use of oral pre-exposure prophylaxis in pregnant and postpartum women: a qualitative meta-synthesis.
Liu Y, Zhang L, Chen H
BMC Public Health 2024 Jun 20;24(1):1653. doi: 10.1186/s12889-024-19168-4. PMID: 38902766Free PMC Article
Safety and efficacy of long-acting injectable cabotegravir as preexposure prophylaxis to prevent HIV acquisition.
Fonner VA, Ridgeway K, van der Straten A, Lorenzetti L, Dinh N, Rodolph M, Schaefer R, Schmidt HA, Nguyen VTT, Radebe M, Peralta H, Baggaley R
AIDS 2023 May 1;37(6):957-966. Epub 2023 Jan 25 doi: 10.1097/QAD.0000000000003494. PMID: 36723489Free PMC Article
Haemophagocytic lymphohistiocytosis in human immunodeficiency virus: a systematic review of literature.
Fazal F, Gupta N, Mittal A, Ray A
Drug Discov Ther 2020 Nov 4;14(5):226-231. Epub 2020 Oct 29 doi: 10.5582/ddt.2020.03069. PMID: 33116036
Acute and early HIV infection screening among men who have sex with men, a systematic review and meta-analysis.
Palmer S, Dijkstra M, Ket JC, Wahome EW, Walimbwa J, Gichuru E, van der Elst EM, Schim van der Loeff MF, de Bree GJ, Sanders EJ
J Int AIDS Soc 2020 Oct;23 Suppl 6(Suppl 6):e25590. doi: 10.1002/jia2.25590. PMID: 33000916Free PMC Article
Systematic review of the performance and clinical utility of point of care HIV-1 RNA testing for diagnosis and care.
Agutu CA, Ngetsa CJ, Price MA, Rinke de Wit TF, Omosa-Manyonyi G, Sanders EJ, Graham SM
PLoS One 2019;14(6):e0218369. Epub 2019 Jun 27 doi: 10.1371/journal.pone.0218369. PMID: 31246963Free PMC Article

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