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Adrenocortical hyperplasia

MedGen UID:
83343
Concept ID:
C0342494
Disease or Syndrome
Synonyms: Adrenal Cortex Hyperplasia; Adrenal Cortical Hyperplasia; Adrenocortical Hyperplasia; Hyperplasia of Adrenal Cortex; Hyperplasia of the Adrenal Cortex
SNOMED CT: Adrenocortical hyperplasia (237777008)
 
HPO: HP:6000152

Definition

A non-malignant growth, or enlargement, of the adrenal glands, specifically the cortex, although the cortex cannot be definitively identified by conventional imaging. Adrenal cortical hyperplasia is defined radiologically as a non-malignant growth, or enlargement, of the adrenal glands. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdrenocortical hyperplasia

Professional guidelines

PubMed

Zuo R, Liu S, Xu L, Pang H
Curr Hypertens Rep 2023 Dec;25(12):471-480. Epub 2023 Oct 3 doi: 10.1007/s11906-023-01269-x. PMID: 37787864
Yang Y, Reincke M, Williams TA
Best Pract Res Clin Endocrinol Metab 2020 Mar;34(2):101365. Epub 2019 Dec 5 doi: 10.1016/j.beem.2019.101365. PMID: 31837980
Seidel E, Schewe J, Scholl UI
Exp Mol Med 2019 Nov 6;51(11):1-12. doi: 10.1038/s12276-019-0337-9. PMID: 31695023Free PMC Article

Recent clinical studies

Etiology

Yang Y, Reincke M, Williams TA
Best Pract Res Clin Endocrinol Metab 2020 Mar;34(2):101365. Epub 2019 Dec 5 doi: 10.1016/j.beem.2019.101365. PMID: 31837980
Deinum J, Groenewoud H, van der Wilt GJ, Lenzini L, Rossi GP
Eur J Endocrinol 2019 Sep;181(3):D15-D26. doi: 10.1530/EJE-18-0844. PMID: 31176302
Faillot S, Assie G
Eur J Endocrinol 2016 Jun;174(6):R249-65. Epub 2016 Jan 6 doi: 10.1530/EJE-15-1118. PMID: 26739091
Calebiro D, Di Dalmazi G, Bathon K, Ronchi CL, Beuschlein F
Eur J Endocrinol 2015 Oct;173(4):M99-106. Epub 2015 Jul 2 doi: 10.1530/EJE-15-0353. PMID: 26139209
Duan K, Gomez Hernandez K, Mete O
J Clin Pathol 2015 Mar;68(3):175-86. Epub 2014 Nov 25 doi: 10.1136/jclinpath-2014-202612. PMID: 25425660

Diagnosis

Bourdeau I, Parisien-La Salle S, Lacroix A
Best Pract Res Clin Endocrinol Metab 2020 May;34(3):101386. Epub 2020 Feb 4 doi: 10.1016/j.beem.2020.101386. PMID: 32115357
Jouinot A, Armignacco R, Assié G
J Steroid Biochem Mol Biol 2019 Oct;193:105414. Epub 2019 Jun 14 doi: 10.1016/j.jsbmb.2019.105414. PMID: 31207362
Lodish MB, Keil MF, Stratakis CA
Endocrinol Metab Clin North Am 2018 Jun;47(2):451-462. doi: 10.1016/j.ecl.2018.02.008. PMID: 29754644Free PMC Article
Stratakis CA
Ann Endocrinol (Paris) 2018 Jun;79(3):125-131. Epub 2018 Apr 9 doi: 10.1016/j.ando.2018.03.010. PMID: 29650225
Bertagna X, Guignat L, Groussin L, Bertherat J
Best Pract Res Clin Endocrinol Metab 2009 Oct;23(5):607-23. doi: 10.1016/j.beem.2009.06.001. PMID: 19945026

Therapy

Zuo R, Liu S, Xu L, Pang H
Curr Hypertens Rep 2023 Dec;25(12):471-480. Epub 2023 Oct 3 doi: 10.1007/s11906-023-01269-x. PMID: 37787864
Nadella K, Faucz FR, Stratakis CA
Endocr Relat Cancer 2020 Oct;27(10):591-599. doi: 10.1530/ERC-20-0270. PMID: 32738126Free PMC Article
Deinum J, Groenewoud H, van der Wilt GJ, Lenzini L, Rossi GP
Eur J Endocrinol 2019 Sep;181(3):D15-D26. doi: 10.1530/EJE-18-0844. PMID: 31176302
El-Maouche D, Hannah-Shmouni F, Mallappa A, Hargreaves CJ, Avila NA, Merke DP
Clin Endocrinol (Oxf) 2019 Aug;91(2):247-255. Epub 2019 May 7 doi: 10.1111/cen.13996. PMID: 31001843Free PMC Article
Stratakis CA
Ann Endocrinol (Paris) 2018 Jun;79(3):125-131. Epub 2018 Apr 9 doi: 10.1016/j.ando.2018.03.010. PMID: 29650225

Prognosis

Yang Y, Reincke M, Williams TA
Best Pract Res Clin Endocrinol Metab 2020 Mar;34(2):101365. Epub 2019 Dec 5 doi: 10.1016/j.beem.2019.101365. PMID: 31837980
Faillot S, Assie G
Eur J Endocrinol 2016 Jun;174(6):R249-65. Epub 2016 Jan 6 doi: 10.1530/EJE-15-1118. PMID: 26739091
Duan K, Gomez Hernandez K, Mete O
J Clin Pathol 2015 Mar;68(3):175-86. Epub 2014 Nov 25 doi: 10.1136/jclinpath-2014-202612. PMID: 25425660
Bertagna X, Guignat L, Groussin L, Bertherat J
Best Pract Res Clin Endocrinol Metab 2009 Oct;23(5):607-23. doi: 10.1016/j.beem.2009.06.001. PMID: 19945026
Mazzuco TL, Bourdeau I, Lacroix A
Curr Opin Endocrinol Diabetes Obes 2009 Jun;16(3):203-10. doi: 10.1097/MED.0b013e32832b7043. PMID: 19390321

Clinical prediction guides

de Arruda Botelho MLA, Nishi MY, Ribeiro KB, Zerbini MCN
Endocr Pathol 2023 Jun;34(2):200-212. Epub 2023 Apr 12 doi: 10.1007/s12022-023-09761-5. PMID: 37043100
Kolli V, da Cunha IW, Kim S, Iben JR, Mallappa A, Li T, Gaynor A, Coon SL, Quezado MM, Merke DP
Front Endocrinol (Lausanne) 2021;12:730947. Epub 2021 Sep 20 doi: 10.3389/fendo.2021.730947. PMID: 34616364Free PMC Article
El-Maouche D, Hannah-Shmouni F, Mallappa A, Hargreaves CJ, Avila NA, Merke DP
Clin Endocrinol (Oxf) 2019 Aug;91(2):247-255. Epub 2019 May 7 doi: 10.1111/cen.13996. PMID: 31001843Free PMC Article
Duan K, Gomez Hernandez K, Mete O
J Clin Pathol 2015 Mar;68(3):175-86. Epub 2014 Nov 25 doi: 10.1136/jclinpath-2014-202612. PMID: 25425660
Bernichtein S, Alevizaki M, Huhtaniemi I
Trends Endocrinol Metab 2008 Sep;19(7):231-8. Epub 2008 Aug 6 doi: 10.1016/j.tem.2008.06.003. PMID: 18691899

Recent systematic reviews

Fan L, Zhang B, Li L, Gong C
Clin Endocrinol (Oxf) 2020 Dec;93(6):687-695. Epub 2020 Jul 27 doi: 10.1111/cen.14277. PMID: 32623730

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