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Hepatic sclerosis

MedGen UID:
574394
•Concept ID:
C0341446
•
Disease or Syndrome
Synonym: Hepatic Sclerosis
SNOMED CT: Hepatic sclerosis (235899008)

Definition

A thickening of the liver parenchyma. Hepatic sclerosis, fibrosis and cirrhosis may exist along a continuum. [from NCI]

Professional guidelines

PubMed

L-Carnitine in the Treatment of Psychiatric and Neurological Manifestations: A Systematic Review.
Wang W, Pan D, Liu Q, Chen X, Wang S
Nutrients 2024 Apr 20;16(8) doi: 10.3390/nu16081232. PMID: 38674921Free PMC Article
Unusual Primary Neoplasms of the Adult Liver: Review of Imaging Appearances and Differential Diagnosis.
Razik A, Malla S, Goyal A, Gamanagatti S, Kandasamy D, Das CJ, Sharma R, Gupta AK
Curr Probl Diagn Radiol 2022 Jan-Feb;51(1):73-85. Epub 2020 Nov 2 doi: 10.1067/j.cpradiol.2020.10.001. PMID: 33199074
Hepatic hydrothorax. Cause and management.
Alberts WM, Salem AJ, Solomon DA, Boyce G
Arch Intern Med 1991 Dec;151(12):2383-8. PMID: 1746994

Recent clinical studies

Etiology

Serum Expression Level of MicroRNA-122 and its Significance in different Stages of Hepatitis B Virus Infection.
Singh SP, Maurya V, Kumar K, Singh D, Verma P, Samanta D, Verma MK
Cell Mol Biol (Noisy-le-grand) 2023 Jun 30;69(6):36-40. doi: 10.14715/cmb/2023.69.6.6. PMID: 37605594
A Pharmacokinetic Drug-Drug Interactions Study between Entecavir and Hydronidone, a Potential Novel Antifibrotic Small Molecule, in Healthy Male Volunteers.
Zhang R, Li P, Guo P, Zhou J, Wan J, Yang C, Zhou J, Liu Y, Shi S
Adv Ther 2023 Feb;40(2):658-670. Epub 2022 Dec 7 doi: 10.1007/s12325-022-02377-x. PMID: 36477590
Chemokine CXCL1 may serve as a potential molecular target for hepatocellular carcinoma.
Han KQ, Han H, He XQ, Wang L, Guo XD, Zhang XM, Chen J, Zhu QG, Nian H, Zhai XF, Jiang MW
Cancer Med 2016 Oct;5(10):2861-2871. Epub 2016 Sep 28 doi: 10.1002/cam4.843. PMID: 27682863Free PMC Article

Diagnosis

Serum Expression Level of MicroRNA-122 and its Significance in different Stages of Hepatitis B Virus Infection.
Singh SP, Maurya V, Kumar K, Singh D, Verma P, Samanta D, Verma MK
Cell Mol Biol (Noisy-le-grand) 2023 Jun 30;69(6):36-40. doi: 10.14715/cmb/2023.69.6.6. PMID: 37605594
Chemokine CXCL1 may serve as a potential molecular target for hepatocellular carcinoma.
Han KQ, Han H, He XQ, Wang L, Guo XD, Zhang XM, Chen J, Zhu QG, Nian H, Zhai XF, Jiang MW
Cancer Med 2016 Oct;5(10):2861-2871. Epub 2016 Sep 28 doi: 10.1002/cam4.843. PMID: 27682863Free PMC Article

Therapy

A Pharmacokinetic Drug-Drug Interactions Study between Entecavir and Hydronidone, a Potential Novel Antifibrotic Small Molecule, in Healthy Male Volunteers.
Zhang R, Li P, Guo P, Zhou J, Wan J, Yang C, Zhou J, Liu Y, Shi S
Adv Ther 2023 Feb;40(2):658-670. Epub 2022 Dec 7 doi: 10.1007/s12325-022-02377-x. PMID: 36477590

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