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Progressive massive fibrosis

MedGen UID:
573584
Concept ID:
C0340170
Disease or Syndrome
Synonyms: Complicated pneumoconiosis; PMF - Progressive massive fibrosis
SNOMED CT: Complicated pneumoconiosis (233749003); Progressive massive fibrosis (233749003); PMF - Progressive massive fibrosis (233749003)
 
HPO: HP:0033706

Definition

This condition is caused by slow-growing conglomeration of dust particles and collagen deposition in individuals (mostly coal workers) heavily exposed to inorganic dust. Progressive massive fibrosis manifests as masslike lesions, usually bilateral and in the upper lobes. Background nodular opacities reflect accompanying pneumoconiosis, with or without emphysematous destruction adjacent to the massive fibrosis. Lesions similar to progressive massive fibrosis sometimes occur in other conditions, such as sarcoidosis and talcosis. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProgressive massive fibrosis

Professional guidelines

PubMed

Kizil GV, Donoghue AM
Occup Med (Lond) 2002 May;52(3):137-49. doi: 10.1093/occmed/52.3.137. PMID: 12063359

Recent clinical studies

Etiology

Cool CD, Murray J, Vorajee NI, Rose CS, Zell-Baran LM, Sanyal S, Franko AD, Almberg KS, Iwaniuk C, Go LHT, Green FHY, Cohen RA
Arch Pathol Lab Med 2024 Jul 1;148(7):805-817. doi: 10.5858/arpa.2022-0491-OA. PMID: 37852172
Weissman DN
Pharmacol Ther 2022 Dec;240:108232. Epub 2022 Jun 19 doi: 10.1016/j.pharmthera.2022.108232. PMID: 35732247Free PMC Article
Sari G, Koyuncu A, Şimşek C
J Occup Environ Med 2022 Jul 1;64(7):557-561. Epub 2022 Jun 8 doi: 10.1097/JOM.0000000000002545. PMID: 35673264
Zosky GR, Hoy RF, Silverstone EJ, Brims FJ, Miles S, Johnson AR, Gibson PG, Yates DH
Med J Aust 2016 Jun 20;204(11):414-8. doi: 10.5694/mja16.00357. PMID: 27318401
Yucesoy B, Luster MI
Toxicol Lett 2007 Feb 5;168(3):249-54. Epub 2006 Nov 16 doi: 10.1016/j.toxlet.2006.10.021. PMID: 17161563

Diagnosis

Churg A, Muller NL
Surg Pathol Clin 2024 Jun;17(2):193-202. Epub 2023 Dec 11 doi: 10.1016/j.path.2023.11.005. PMID: 38692804
Fazio JC, Gandhi SA, Flattery J, Heinzerling A, Kamangar N, Afif N, Cummings KJ, Harrison RJ
JAMA Intern Med 2023 Sep 1;183(9):991-998. doi: 10.1001/jamainternmed.2023.3295. PMID: 37486642Free PMC Article
Weissman DN
Pharmacol Ther 2022 Dec;240:108232. Epub 2022 Jun 19 doi: 10.1016/j.pharmthera.2022.108232. PMID: 35732247Free PMC Article
Seaman DM, Meyer CA, Kanne JP
Clin Chest Med 2015 Jun;36(2):249-68, viii-ix. Epub 2015 Apr 1 doi: 10.1016/j.ccm.2015.02.008. PMID: 26024603
Javidan-Nejad C, Bhalla S
Radiol Clin North Am 2009 Mar;47(2):289-306. doi: 10.1016/j.rcl.2008.11.006. PMID: 19249457

Therapy

Churg A, Muller NL
Surg Pathol Clin 2024 Jun;17(2):193-202. Epub 2023 Dec 11 doi: 10.1016/j.path.2023.11.005. PMID: 38692804
Cool CD, Murray J, Vorajee NI, Rose CS, Zell-Baran LM, Sanyal S, Franko AD, Almberg KS, Iwaniuk C, Go LHT, Green FHY, Cohen RA
Arch Pathol Lab Med 2024 Jul 1;148(7):805-817. doi: 10.5858/arpa.2022-0491-OA. PMID: 37852172
Hall NB, Blackley DJ, Halldin CN, Laney AS
Curr Environ Health Rep 2019 Sep;6(3):137-147. doi: 10.1007/s40572-019-00237-5. PMID: 31302880Free PMC Article
Seaman DM, Meyer CA, Kanne JP
Clin Chest Med 2015 Jun;36(2):249-68, viii-ix. Epub 2015 Apr 1 doi: 10.1016/j.ccm.2015.02.008. PMID: 26024603
Yucesoy B, Luster MI
Toxicol Lett 2007 Feb 5;168(3):249-54. Epub 2006 Nov 16 doi: 10.1016/j.toxlet.2006.10.021. PMID: 17161563

Prognosis

Cho U, Kim TE, Park CK, Yoon HK, Sa YJ, Kim HL, Kim TJ
Int J Environ Res Public Health 2022 Nov 14;19(22) doi: 10.3390/ijerph192214975. PMID: 36429692Free PMC Article
Reilly MJ, Timmer SJ, Rosenman KD
Ann Am Thorac Soc 2018 Dec;15(12):1404-1410. doi: 10.1513/AnnalsATS.201802-117OC. PMID: 30188758Free PMC Article
Bakan ND, Özkan G, Çamsari G, Gür A, Bayram M, Açikmeşe B, Çetinkaya E
Chest 2011 Nov;140(5):1300-1304. Epub 2011 May 5 doi: 10.1378/chest.10-1856. PMID: 21546437
Schreiber J, Koschel D, Kekow J, Waldburg N, Goette A, Merget R
Eur J Intern Med 2010 Jun;21(3):168-72. Epub 2010 Mar 2 doi: 10.1016/j.ejim.2010.02.004. PMID: 20493416
Rosenman KD, Reilly MJ, Kalinowski DJ, Watt FC
Chest 1997 Mar;111(3):779-86. doi: 10.1378/chest.111.3.779. PMID: 9118719

Clinical prediction guides

Cool CD, Murray J, Vorajee NI, Rose CS, Zell-Baran LM, Sanyal S, Franko AD, Almberg KS, Iwaniuk C, Go LHT, Green FHY, Cohen RA
Arch Pathol Lab Med 2024 Jul 1;148(7):805-817. doi: 10.5858/arpa.2022-0491-OA. PMID: 37852172
Tang M, Tan F, Luo Y, Xiao X, Deng X, Li S, Tan X
BMC Pulm Med 2023 Aug 9;23(1):290. doi: 10.1186/s12890-023-02577-3. PMID: 37559034Free PMC Article
Cho U, Kim TE, Park CK, Yoon HK, Sa YJ, Kim HL, Kim TJ
Int J Environ Res Public Health 2022 Nov 14;19(22) doi: 10.3390/ijerph192214975. PMID: 36429692Free PMC Article
Sari G, Koyuncu A, Şimşek C
J Occup Environ Med 2022 Jul 1;64(7):557-561. Epub 2022 Jun 8 doi: 10.1097/JOM.0000000000002545. PMID: 35673264
Sarı G, Gökçek A, Koyuncu A, Şimşek C
Med Lav 2022 Feb 22;113(1):e2022002. doi: 10.23749/mdl.v113i1.12303. PMID: 35226653Free PMC Article

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