U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

X-linked retinitis pigmentosa

MedGen UID:
573215
Concept ID:
C0339528
Congenital Abnormality
SNOMED CT: X-linked retinitis pigmentosa (232054005)

Professional guidelines

PubMed

Parmeggiani F, Barbaro V, Migliorati A, Raffa P, Nespeca P, De Nadai K, Del Vecchio C, Palù G, Parolin C, Di Iorio E
Eur J Ophthalmol 2017 Mar 10;27(2):240-248. Epub 2016 Oct 21 doi: 10.5301/ejo.5000879. PMID: 27768226
Veltel S, Wittinghofer A
Expert Opin Ther Targets 2009 Oct;13(10):1239-51. doi: 10.1517/14728220903225016. PMID: 19702441
Kaplan J, Pelet A, Martin C, Delrieu O, Aymé S, Bonneau D, Briard ML, Hanauer A, Larget-Piet L, Lefrançois P
J Med Genet 1992 Sep;29(9):615-23. doi: 10.1136/jmg.29.9.615. PMID: 1357178Free PMC Article

Recent clinical studies

Etiology

Michaelides M, Besirli CG, Yang Y, DE Guimaraes TAC, Wong SC, Huckfeldt RM, Comander JI, Sahel JA, Shah SM, Tee JJL, Kumaran N, Georgiadis A, Minnick P, Zeldin R, Naylor S, Xu J, Clark M, Anglade E, Wong P, Fleck PR, Fung A, Peluso C, Kalitzeos A, Georgiou M, Ripamonti C, Smith AJ, Ali RR, Forbes A, Bainbridge J
Am J Ophthalmol 2024 Nov;267:122-134. Epub 2024 Jun 12 doi: 10.1016/j.ajo.2024.05.034. PMID: 38871269
Lam BL, Pennesi ME, Kay CN, Panda S, Gow JA, Zhao G, MacLaren RE; XIRIUS Study Group
Ophthalmology 2024 Sep;131(9):1083-1093. Epub 2024 Feb 28 doi: 10.1016/j.ophtha.2024.02.023. PMID: 38423215
Gocuk SA, Jolly JK, Edwards TL, Ayton LN
Prog Retin Eye Res 2023 Sep;96:101190. Epub 2023 Jul 3 doi: 10.1016/j.preteyeres.2023.101190. PMID: 37406879
von Krusenstiern L, Liu J, Liao E, Gow JA, Chen G, Ong T, Lotery AJ, Jalil A, Lam BL, MacLaren RE; XIRIUS Part 1 Study GroupXOLARIS Study Group
JAMA Ophthalmol 2023 Mar 1;141(3):275-283. doi: 10.1001/jamaophthalmol.2022.6254. PMID: 36757689Free PMC Article
Lyraki R, Megaw R, Hurd T
Biochem Soc Trans 2016 Oct 15;44(5):1235-1244. doi: 10.1042/BST20160148. PMID: 27911705

Diagnosis

Gocuk SA, Jolly JK, Edwards TL, Ayton LN
Prog Retin Eye Res 2023 Sep;96:101190. Epub 2023 Jul 3 doi: 10.1016/j.preteyeres.2023.101190. PMID: 37406879
Vinikoor-Imler LC, Simpson C, Narayanan D, Abbasi S, Lally C
Ophthalmic Genet 2022 Oct;43(5):581-588. Epub 2022 Aug 25 doi: 10.1080/13816810.2022.2109686. PMID: 36004681
Wuthisiri W, Lingao MD, Capasso JE, Levin AV
Curr Opin Ophthalmol 2013 Sep;24(5):389-97. doi: 10.1097/ICU.0b013e3283641f91. PMID: 23892913
Bird AC
Br J Ophthalmol 1975 Apr;59(4):177-99. doi: 10.1136/bjo.59.4.177. PMID: 1138842Free PMC Article
Jay B, Bird A
Trans Am Acad Ophthalmol Otolaryngol 1973 Sep-Oct;77(5):OP641-51. PMID: 4784907

Therapy

Lam BL, Pennesi ME, Kay CN, Panda S, Gow JA, Zhao G, MacLaren RE; XIRIUS Study Group
Ophthalmology 2024 Sep;131(9):1083-1093. Epub 2024 Feb 28 doi: 10.1016/j.ophtha.2024.02.023. PMID: 38423215
Sladen PE, Naeem A, Adefila-Ideozu T, Vermeule T, Busson SL, Michaelides M, Naylor S, Forbes A, Lane A, Georgiadis A
Int J Mol Sci 2024 Feb 2;25(3) doi: 10.3390/ijms25031839. PMID: 38339118Free PMC Article
von Krusenstiern L, Liu J, Liao E, Gow JA, Chen G, Ong T, Lotery AJ, Jalil A, Lam BL, MacLaren RE; XIRIUS Part 1 Study GroupXOLARIS Study Group
JAMA Ophthalmol 2023 Mar 1;141(3):275-283. doi: 10.1001/jamaophthalmol.2022.6254. PMID: 36757689Free PMC Article
Piotter E, McClements ME, MacLaren RE
Biomolecules 2021 Aug 9;11(8) doi: 10.3390/biom11081179. PMID: 34439845Free PMC Article
Cehajic-Kapetanovic J, Xue K, Martinez-Fernandez de la Camara C, Nanda A, Davies A, Wood LJ, Salvetti AP, Fischer MD, Aylward JW, Barnard AR, Jolly JK, Luo E, Lujan BJ, Ong T, Girach A, Black GCM, Gregori NZ, Davis JL, Rosa PR, Lotery AJ, Lam BL, Stanga PE, MacLaren RE
Nat Med 2020 Mar;26(3):354-359. Epub 2020 Feb 24 doi: 10.1038/s41591-020-0763-1. PMID: 32094925Free PMC Article

Prognosis

Koller S, Beltraminelli T, Maggi J, Wlodarczyk A, Feil S, Baehr L, Gerth-Kahlert C, Menghini M, Berger W
Genes (Basel) 2023 Apr 18;14(4) doi: 10.3390/genes14040934. PMID: 37107692Free PMC Article
Piotter E, McClements ME, MacLaren RE
Biomolecules 2021 Aug 9;11(8) doi: 10.3390/biom11081179. PMID: 34439845Free PMC Article
Kortüm F, Kieninger S, Mazzola P, Kohl S, Wissinger B, Prokisch H, Stingl K, Weisschuh N
Int J Mol Sci 2021 Jan 16;22(2) doi: 10.3390/ijms22020850. PMID: 33467000Free PMC Article
Menghini M, Jolly JK, Nanda A, Wood L, Cehajic-Kapetanovic J, MacLaren RE
Ophthalmologica 2021;244(4):281-290. Epub 2020 Mar 26 doi: 10.1159/000507484. PMID: 32209785
Vervoort R, Wright AF
Hum Mutat 2002 May;19(5):486-500. doi: 10.1002/humu.10057. PMID: 11968081

Clinical prediction guides

Lam BL, Pennesi ME, Kay CN, Panda S, Gow JA, Zhao G, MacLaren RE; XIRIUS Study Group
Ophthalmology 2024 Sep;131(9):1083-1093. Epub 2024 Feb 28 doi: 10.1016/j.ophtha.2024.02.023. PMID: 38423215
Koller S, Beltraminelli T, Maggi J, Wlodarczyk A, Feil S, Baehr L, Gerth-Kahlert C, Menghini M, Berger W
Genes (Basel) 2023 Apr 18;14(4) doi: 10.3390/genes14040934. PMID: 37107692Free PMC Article
Kortüm F, Kieninger S, Mazzola P, Kohl S, Wissinger B, Prokisch H, Stingl K, Weisschuh N
Int J Mol Sci 2021 Jan 16;22(2) doi: 10.3390/ijms22020850. PMID: 33467000Free PMC Article
Cehajic-Kapetanovic J, Xue K, Martinez-Fernandez de la Camara C, Nanda A, Davies A, Wood LJ, Salvetti AP, Fischer MD, Aylward JW, Barnard AR, Jolly JK, Luo E, Lujan BJ, Ong T, Girach A, Black GCM, Gregori NZ, Davis JL, Rosa PR, Lotery AJ, Lam BL, Stanga PE, MacLaren RE
Nat Med 2020 Mar;26(3):354-359. Epub 2020 Feb 24 doi: 10.1038/s41591-020-0763-1. PMID: 32094925Free PMC Article
Vervoort R, Wright AF
Hum Mutat 2002 May;19(5):486-500. doi: 10.1002/humu.10057. PMID: 11968081

Recent systematic reviews

Lam BL, Scholl HPN, Doub D, Sperling M, Hashim M, Li N
Retina 2024 Jan 1;44(1):1-9. doi: 10.1097/IAE.0000000000003920. PMID: 37683184
Zada M, Cornish EE, Fraser CL, Jamieson RV, Grigg JR
Acta Ophthalmol 2021 Aug;99(5):499-510. Epub 2020 Nov 30 doi: 10.1111/aos.14662. PMID: 33258268

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...