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Infantile cataract

MedGen UID:
452437
•Concept ID:
C0339358
•
Congenital Abnormality
Synonyms: Cataracts, infantile; Infantile cataracts
SNOMED CT: Infantile cataract (399120006)

Professional guidelines

PubMed

Current management of infantile cataracts.
Lenhart PD, Lambert SR
Surv Ophthalmol 2022 Sep-Oct;67(5):1476-1505. Epub 2022 Mar 17 doi: 10.1016/j.survophthal.2022.03.005. PMID: 35307324Free PMC Article
Congenital and infantile cataract: aetiology and management.
Chan WH, Biswas S, Ashworth JL, Lloyd IC
Eur J Pediatr 2012 Apr;171(4):625-30. Epub 2012 Mar 1 doi: 10.1007/s00431-012-1700-1. PMID: 22383071
Monocular infantile cataract: treatment is worth the effort.
Repka MX
Arch Ophthalmol 2010 Jul;128(7):931-3. doi: 10.1001/archophthalmol.2010.130. PMID: 20625058

Recent clinical studies

Etiology

Long-term strabismus outcomes after unilateral infantile cataract surgery in the Infant Aphakia Treatment Study.
Bothun ED, Shainberg MJ, Christiansen SP, Vanderveen DK, Neely DE, Kruger SJ, Cotsonis G, Lambert SR; Infant Aphakic Treatment Study
J AAPOS 2022 Aug;26(4):174.e1-174.e4. Epub 2022 Jul 14 doi: 10.1016/j.jaapos.2022.05.003. PMID: 35843488Free PMC Article
Current management of infantile cataracts.
Lenhart PD, Lambert SR
Surv Ophthalmol 2022 Sep-Oct;67(5):1476-1505. Epub 2022 Mar 17 doi: 10.1016/j.survophthal.2022.03.005. PMID: 35307324Free PMC Article
Infantile cataract: comparison of two surgical approaches.
Khatib N, Tsumi E, Baidousi A, Nussinovitch H, Bilenko N, Lifshitz T, Levy J
Can J Ophthalmol 2017 Oct;52(5):527-532. Epub 2017 Jul 5 doi: 10.1016/j.jcjo.2017.02.023. PMID: 28985816
Accuracy of routine data on paediatric cataract in the UK compared to active surveillance: lessons from the IOLu2 study.
Solebo AL, Russell-Eggitt I, Rahi JS; British Congenital Cataract Interest Group; British Isles Congenital Cataract Interest Group (BCCIG)
Br J Ophthalmol 2013 Jun;97(6):757-9. Epub 2013 Apr 12 doi: 10.1136/bjophthalmol-2012-302679. PMID: 23584717
Coats' disease and bilateral cataract in a child with Turner syndrome: a case report.
Beby F, Roche O, Burillon C, Denis P
Graefes Arch Clin Exp Ophthalmol 2005 Dec;243(12):1291-3. Epub 2005 Jun 14 doi: 10.1007/s00417-005-1194-x. PMID: 15959738

Diagnosis

Infantile cataract: comparison of two surgical approaches.
Khatib N, Tsumi E, Baidousi A, Nussinovitch H, Bilenko N, Lifshitz T, Levy J
Can J Ophthalmol 2017 Oct;52(5):527-532. Epub 2017 Jul 5 doi: 10.1016/j.jcjo.2017.02.023. PMID: 28985816
Congenital and infantile cataract: aetiology and management.
Chan WH, Biswas S, Ashworth JL, Lloyd IC
Eur J Pediatr 2012 Apr;171(4):625-30. Epub 2012 Mar 1 doi: 10.1007/s00431-012-1700-1. PMID: 22383071
Medulloepithelioma masquerading as chronic anterior granulomatous uveitis.
Kanavi MR, Soheilian M, Kamrava K, Peyman GA
Can J Ophthalmol 2007 Jun;42(3):474-6. PMID: 17508050
Coats' disease and bilateral cataract in a child with Turner syndrome: a case report.
Beby F, Roche O, Burillon C, Denis P
Graefes Arch Clin Exp Ophthalmol 2005 Dec;243(12):1291-3. Epub 2005 Jun 14 doi: 10.1007/s00417-005-1194-x. PMID: 15959738
Indications for infantile cataract surgery.
Hiles DA, Biglan AW
Int Ophthalmol Clin 1977 Winter;17(4):39-45. PMID: 924736

Therapy

Long-term strabismus outcomes after unilateral infantile cataract surgery in the Infant Aphakia Treatment Study.
Bothun ED, Shainberg MJ, Christiansen SP, Vanderveen DK, Neely DE, Kruger SJ, Cotsonis G, Lambert SR; Infant Aphakic Treatment Study
J AAPOS 2022 Aug;26(4):174.e1-174.e4. Epub 2022 Jul 14 doi: 10.1016/j.jaapos.2022.05.003. PMID: 35843488Free PMC Article
Visual outcomes and complications in infantile cataract surgery: a real - world scenario.
Chattannavar G, Badakere A, Mohamed A, Kekunnaya R
BMJ Open Ophthalmol 2022;7(1):e000744. Epub 2022 Mar 8 doi: 10.1136/bmjophth-2021-000744. PMID: 35342821Free PMC Article
Current management of infantile cataracts.
Lenhart PD, Lambert SR
Surv Ophthalmol 2022 Sep-Oct;67(5):1476-1505. Epub 2022 Mar 17 doi: 10.1016/j.survophthal.2022.03.005. PMID: 35307324Free PMC Article
Evaluating the evidence for and against the use of IOLs in infants and young children.
Kumar P, Lambert SR
Expert Rev Med Devices 2016;13(4):381-9. Epub 2016 Feb 29 doi: 10.1586/17434440.2016.1153967. PMID: 26878234Free PMC Article
Efficacy of subtenon block in infants - a comparison with intravenous fentanyl for perioperative analgesia in infantile cataract surgery.
Sethi S, Ghai B, Sen I, Ram J, Wig J
Paediatr Anaesth 2013 Nov;23(11):1015-20. Epub 2013 Aug 6 doi: 10.1111/pan.12227. PMID: 23919432

Prognosis

Long-term strabismus outcomes after unilateral infantile cataract surgery in the Infant Aphakia Treatment Study.
Bothun ED, Shainberg MJ, Christiansen SP, Vanderveen DK, Neely DE, Kruger SJ, Cotsonis G, Lambert SR; Infant Aphakic Treatment Study
J AAPOS 2022 Aug;26(4):174.e1-174.e4. Epub 2022 Jul 14 doi: 10.1016/j.jaapos.2022.05.003. PMID: 35843488Free PMC Article
Current management of infantile cataracts.
Lenhart PD, Lambert SR
Surv Ophthalmol 2022 Sep-Oct;67(5):1476-1505. Epub 2022 Mar 17 doi: 10.1016/j.survophthal.2022.03.005. PMID: 35307324Free PMC Article
Pharmacological approaches to restoring lens transparency: Real world applications.
Skinner C, Miraldi Utz V
Ophthalmic Genet 2017 May-Jun;38(3):201-205. Epub 2016 Sep 20 doi: 10.1080/13816810.2016.1214971. PMID: 27648776
Congenital and infantile cataract: aetiology and management.
Chan WH, Biswas S, Ashworth JL, Lloyd IC
Eur J Pediatr 2012 Apr;171(4):625-30. Epub 2012 Mar 1 doi: 10.1007/s00431-012-1700-1. PMID: 22383071
Infantile cataracts.
Lambert SR, Drack AV
Surv Ophthalmol 1996 May-Jun;40(6):427-58. doi: 10.1016/s0039-6257(96)82011-x. PMID: 8724637

Clinical prediction guides

Visual outcomes and complications in infantile cataract surgery: a real - world scenario.
Chattannavar G, Badakere A, Mohamed A, Kekunnaya R
BMJ Open Ophthalmol 2022;7(1):e000744. Epub 2022 Mar 8 doi: 10.1136/bmjophth-2021-000744. PMID: 35342821Free PMC Article
Visual Rehabilitation in Pediatric Aphakia.
Repka MX
Dev Ophthalmol 2016;57:49-68. Epub 2016 Apr 1 doi: 10.1159/000442501. PMID: 27043392
Efficacy of subtenon block in infants - a comparison with intravenous fentanyl for perioperative analgesia in infantile cataract surgery.
Sethi S, Ghai B, Sen I, Ram J, Wig J
Paediatr Anaesth 2013 Nov;23(11):1015-20. Epub 2013 Aug 6 doi: 10.1111/pan.12227. PMID: 23919432
Congenital and infantile cataract: aetiology and management.
Chan WH, Biswas S, Ashworth JL, Lloyd IC
Eur J Pediatr 2012 Apr;171(4):625-30. Epub 2012 Mar 1 doi: 10.1007/s00431-012-1700-1. PMID: 22383071
Coats' disease and bilateral cataract in a child with Turner syndrome: a case report.
Beby F, Roche O, Burillon C, Denis P
Graefes Arch Clin Exp Ophthalmol 2005 Dec;243(12):1291-3. Epub 2005 Jun 14 doi: 10.1007/s00417-005-1194-x. PMID: 15959738

Recent systematic reviews

Nongenetic risk factors for infantile cataracts: Systematic review of observational studies.
Nalbandyan M, Papadopoulos EA, Leckman-Westin E, Browne ML
Birth Defects Res 2021 Sep 1;113(15):1112-1129. Epub 2021 May 5 doi: 10.1002/bdr2.1904. PMID: 33949794

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