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Cerebral venous sinus thrombosis

MedGen UID:
572643
Concept ID:
C0338573
Disease or Syndrome
Synonym: Thrombosis of intracranial venous sinus
SNOMED CT: Thrombosis of intracranial venous sinus (192759008); Cerebral venous sinus thrombosis (192759008)
 
HPO: HP:0033724

Definition

An intracranial thrombosis of the venous sinuses. These typically present with headache, seizures or venous stroke secondary to raised cerebral venous pressure. Cerebral venous sinus thromboses usually affect larger areas of brain parenchyma than those affected by cerebral vein thromboses. [from HPO]

Term Hierarchy

Professional guidelines

PubMed

Bejjani A, Khairani CD, Assi A, Piazza G, Sadeghipour P, Talasaz AH, Fanikos J, Connors JM, Siegal DM, Barnes GD, Martin KA, Angiolillo DJ, Kleindorfer D, Monreal M, Jimenez D, Middeldorp S, Elkind MSV, Ruff CT, Goldhaber SZ, Krumholz HM, Mehran R, Cushman M, Eikelboom JW, Lip GYH, Weitz JI, Lopes RD, Bikdeli B
J Am Coll Cardiol 2024 Jan 23;83(3):444-465. doi: 10.1016/j.jacc.2023.10.038. PMID: 38233019
Sader N, de Lotbinière-Bassett M, Tso MK, Hamilton M
Neurosurg Clin N Am 2018 Oct;29(4):585-594. doi: 10.1016/j.nec.2018.06.011. PMID: 30223971
Saposnik G, Barinagarrementeria F, Brown RD Jr, Bushnell CD, Cucchiara B, Cushman M, deVeber G, Ferro JM, Tsai FY; American Heart Association Stroke Council and the Council on Epidemiology and Prevention
Stroke 2011 Apr;42(4):1158-92. Epub 2011 Feb 3 doi: 10.1161/STR.0b013e31820a8364. PMID: 21293023

Recent clinical studies

Etiology

Faksova K, Walsh D, Jiang Y, Griffin J, Phillips A, Gentile A, Kwong JC, Macartney K, Naus M, Grange Z, Escolano S, Sepulveda G, Shetty A, Pillsbury A, Sullivan C, Naveed Z, Janjua NZ, Giglio N, Perälä J, Nasreen S, Gidding H, Hovi P, Vo T, Cui F, Deng L, Cullen L, Artama M, Lu H, Clothier HJ, Batty K, Paynter J, Petousis-Harris H, Buttery J, Black S, Hviid A
Vaccine 2024 Apr 2;42(9):2200-2211. Epub 2024 Feb 12 doi: 10.1016/j.vaccine.2024.01.100. PMID: 38350768
Ahmad SJ, Feigen CM, Vazquez JP, Kobets AJ, Altschul DJ
J Integr Neurosci 2022 Apr 6;21(3):77. doi: 10.31083/j.jin2103077. PMID: 35633158
Shaban A, Leira EC
Curr Neurol Neurosci Rep 2019 Nov 26;19(12):97. doi: 10.1007/s11910-019-1012-1. PMID: 31773306
Capecchi M, Abbattista M, Martinelli I
J Thromb Haemost 2018 Oct;16(10):1918-1931. Epub 2018 Jul 11 doi: 10.1111/jth.14210. PMID: 29923367
Kernan WN, Ovbiagele B, Black HR, Bravata DM, Chimowitz MI, Ezekowitz MD, Fang MC, Fisher M, Furie KL, Heck DV, Johnston SC, Kasner SE, Kittner SJ, Mitchell PH, Rich MW, Richardson D, Schwamm LH, Wilson JA; American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, and Council on Peripheral Vascular Disease
Stroke 2014 Jul;45(7):2160-236. Epub 2014 May 1 doi: 10.1161/STR.0000000000000024. PMID: 24788967

Diagnosis

Moraes Junior AAA, Conforto AB
Arq Neuropsiquiatr 2022 May;80(5 Suppl 1):53-59. doi: 10.1590/0004-282X-ANP-2022-S108. PMID: 35976298Free PMC Article
Shaban A, Leira EC
Curr Neurol Neurosci Rep 2019 Nov 26;19(12):97. doi: 10.1007/s11910-019-1012-1. PMID: 31773306
Capecchi M, Abbattista M, Martinelli I
J Thromb Haemost 2018 Oct;16(10):1918-1931. Epub 2018 Jul 11 doi: 10.1111/jth.14210. PMID: 29923367
Tan AP, Svrckova P, Cowan F, Chong WK, Mankad K
Eur J Paediatr Neurol 2018 Jul;22(4):690-717. Epub 2018 Apr 24 doi: 10.1016/j.ejpn.2018.04.008. PMID: 29731328
Saposnik G, Barinagarrementeria F, Brown RD Jr, Bushnell CD, Cucchiara B, Cushman M, deVeber G, Ferro JM, Tsai FY; American Heart Association Stroke Council and the Council on Epidemiology and Prevention
Stroke 2011 Apr;42(4):1158-92. Epub 2011 Feb 3 doi: 10.1161/STR.0b013e31820a8364. PMID: 21293023

Therapy

Faksova K, Walsh D, Jiang Y, Griffin J, Phillips A, Gentile A, Kwong JC, Macartney K, Naus M, Grange Z, Escolano S, Sepulveda G, Shetty A, Pillsbury A, Sullivan C, Naveed Z, Janjua NZ, Giglio N, Perälä J, Nasreen S, Gidding H, Hovi P, Vo T, Cui F, Deng L, Cullen L, Artama M, Lu H, Clothier HJ, Batty K, Paynter J, Petousis-Harris H, Buttery J, Black S, Hviid A
Vaccine 2024 Apr 2;42(9):2200-2211. Epub 2024 Feb 12 doi: 10.1016/j.vaccine.2024.01.100. PMID: 38350768
Bejjani A, Khairani CD, Assi A, Piazza G, Sadeghipour P, Talasaz AH, Fanikos J, Connors JM, Siegal DM, Barnes GD, Martin KA, Angiolillo DJ, Kleindorfer D, Monreal M, Jimenez D, Middeldorp S, Elkind MSV, Ruff CT, Goldhaber SZ, Krumholz HM, Mehran R, Cushman M, Eikelboom JW, Lip GYH, Weitz JI, Lopes RD, Bikdeli B
J Am Coll Cardiol 2024 Jan 23;83(3):444-465. doi: 10.1016/j.jacc.2023.10.038. PMID: 38233019
Moraes Junior AAA, Conforto AB
Arq Neuropsiquiatr 2022 May;80(5 Suppl 1):53-59. doi: 10.1590/0004-282X-ANP-2022-S108. PMID: 35976298Free PMC Article
Warkentin TE
Semin Hematol 2022 Apr;59(2):59-71. Epub 2022 Feb 20 doi: 10.1053/j.seminhematol.2022.02.005. PMID: 35512902
Capecchi M, Abbattista M, Martinelli I
J Thromb Haemost 2018 Oct;16(10):1918-1931. Epub 2018 Jul 11 doi: 10.1111/jth.14210. PMID: 29923367

Prognosis

Ding R, Li H, Liu Y, Ou W, Zhang X, Chai H, Huang X, Yang W, Wang Q
J Neuroinflammation 2022 Jun 10;19(1):137. doi: 10.1186/s12974-022-02511-0. PMID: 35689216Free PMC Article
Klein NP, Lewis N, Goddard K, Fireman B, Zerbo O, Hanson KE, Donahue JG, Kharbanda EO, Naleway A, Nelson JC, Xu S, Yih WK, Glanz JM, Williams JTB, Hambidge SJ, Lewin BJ, Shimabukuro TT, DeStefano F, Weintraub ES
JAMA 2021 Oct 12;326(14):1390-1399. doi: 10.1001/jama.2021.15072. PMID: 34477808Free PMC Article
Capecchi M, Abbattista M, Martinelli I
J Thromb Haemost 2018 Oct;16(10):1918-1931. Epub 2018 Jul 11 doi: 10.1111/jth.14210. PMID: 29923367
Tan AP, Svrckova P, Cowan F, Chong WK, Mankad K
Eur J Paediatr Neurol 2018 Jul;22(4):690-717. Epub 2018 Apr 24 doi: 10.1016/j.ejpn.2018.04.008. PMID: 29731328
Saip S, Akman-Demir G, Siva A
Handb Clin Neurol 2014;121:1703-23. doi: 10.1016/B978-0-7020-4088-7.00110-3. PMID: 24365442

Clinical prediction guides

Faksova K, Walsh D, Jiang Y, Griffin J, Phillips A, Gentile A, Kwong JC, Macartney K, Naus M, Grange Z, Escolano S, Sepulveda G, Shetty A, Pillsbury A, Sullivan C, Naveed Z, Janjua NZ, Giglio N, Perälä J, Nasreen S, Gidding H, Hovi P, Vo T, Cui F, Deng L, Cullen L, Artama M, Lu H, Clothier HJ, Batty K, Paynter J, Petousis-Harris H, Buttery J, Black S, Hviid A
Vaccine 2024 Apr 2;42(9):2200-2211. Epub 2024 Feb 12 doi: 10.1016/j.vaccine.2024.01.100. PMID: 38350768
Klok FA, Pai M, Huisman MV, Makris M
Lancet Haematol 2022 Jan;9(1):e73-e80. Epub 2021 Nov 11 doi: 10.1016/S2352-3026(21)00306-9. PMID: 34774202Free PMC Article
Warkentin TE, Kaatz S
Thromb Res 2020 Dec;196:38-51. Epub 2020 Aug 10 doi: 10.1016/j.thromres.2020.08.017. PMID: 32841919Free PMC Article
Tan AP, Svrckova P, Cowan F, Chong WK, Mankad K
Eur J Paediatr Neurol 2018 Jul;22(4):690-717. Epub 2018 Apr 24 doi: 10.1016/j.ejpn.2018.04.008. PMID: 29731328
Saip S, Akman-Demir G, Siva A
Handb Clin Neurol 2014;121:1703-23. doi: 10.1016/B978-0-7020-4088-7.00110-3. PMID: 24365442

Recent systematic reviews

Saleh T, Albalkhi I, Matrushi M, Al Mubarak F, Al-Saadi T
World Neurosurg 2024 Sep;189:465-472.e5. Epub 2024 Jul 27 doi: 10.1016/j.wneu.2024.07.043. PMID: 39002775
Alghamdi SR, Cho A, Lam J, Al-Saadi T
J Clin Neurosci 2022 Apr;98:254-260. Epub 2022 Mar 2 doi: 10.1016/j.jocn.2022.01.027. PMID: 35247707
Jaiswal V, Nepal G, Dijamco P, Ishak A, Dagar M, Sarfraz Z, Shama N, Sarfraz A, Lnu K, Mitra S, Agarwala P, Naz S, Song D, Jaiswal A
J Prim Care Community Health 2022 Jan-Dec;13:21501319221074450. doi: 10.1177/21501319221074450. PMID: 35142234Free PMC Article
Sharifian-Dorche M, Bahmanyar M, Sharifian-Dorche A, Mohammadi P, Nomovi M, Mowla A
J Neurol Sci 2021 Sep 15;428:117607. Epub 2021 Aug 3 doi: 10.1016/j.jns.2021.117607. PMID: 34365148Free PMC Article
Kashkoush AI, Ma H, Agarwal N, Panczykowski D, Tonetti D, Weiner GM, Ares W, Kenmuir C, Jadhav A, Jovin T, Jankowitz BT, Gross BA
J Clin Neurosci 2017 May;39:9-15. Epub 2017 Mar 6 doi: 10.1016/j.jocn.2017.02.046. PMID: 28274514

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