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Malignant lymphoma, mixed small and large cell, diffuse

MedGen UID:
569689
•Concept ID:
C0334636
•
Neoplastic Process
Synonyms: Malignant lymphoma, mixed cell type, diffuse; Malignant lymphoma, mixed lymphocytic-histiocytic, diffuse
SNOMED CT: Malignant lymphoma, mixed small and large cell, diffuse (50102004); Malignant lymphoma, mixed lymphocytic-histiocytic, diffuse (50102004); Malignant lymphoma, mixed cell type, diffuse (50102004)

Professional guidelines

PubMed

Targeted treatment and new agents in diffuse large B cell lymphoma.
Dupire S, Coiffier B
Int J Hematol 2010 Jul;92(1):12-24. Epub 2010 Jun 18 doi: 10.1007/s12185-010-0609-6. PMID: 20559762
Clinical management of six cases of low-risk primary tonsillar non-Hodgkin's lymphoma.
Colleoni GW, Oliveira JS, Alves AC, Borducchi DM, Segreto RA, Cervantes O, Kerbauy J
Sao Paulo Med J 1999 Sep 2;117(5):215-7. doi: 10.1590/s1516-31801999000500006. PMID: 10592134
Management of intermediate-grade lymphomas.
Miller TP
Oncology (Williston Park) 1998 Oct;12(10 Suppl 8):35-9. PMID: 9830631

Recent clinical studies

Etiology

A retrospective histopathological survey on canine lymphomas subtypes of Porto District.
Pinello K, Santos M, Dias-Pereira P, Niza-Ribeiro J, de-Matos A
Open Vet J 2023 Apr;13(4):443-450. Epub 2023 Apr 13 doi: 10.5455/OVJ.2023.v13.i4.6. PMID: 37251261Free PMC Article
Efficacy of checkpoint inhibition after CAR-T failure in aggressive B-cell lymphomas: outcomes from 15 US institutions.
Major A, Yu J, Shukla N, Che Y, Karrison TG, Treitman R, Kamdar MK, Haverkos BM, Godfrey J, Babcook MA, Voorhees TJ, Carlson S, Gaut D, Oliai C, Romancik JT, Winter AM, Hill BT, Bansal R, Villasboas Bisneto JC, Nizamuddin IA, Karmali R, Fitzgerald LA, Stephens DM, Pophali PA, Trabolsi A, Schatz JH, Hu M, Bachanova V, Slade MJ, Singh N, Ahmed N, McGuirk JP, Bishop MR, Riedell PA, Kline J
Blood Adv 2023 Aug 22;7(16):4528-4538. doi: 10.1182/bloodadvances.2023010016. PMID: 37026796Free PMC Article
Lymphoma subtypes in India: a tertiary care center review.
Jain S, Lone MR, Goswami A, Mandal T, Panda AK, Ramteke P, Srivastav T, Sharma MC, Gogia A, Sharma A, Bakhshi S, Mahapatra M, Kumar L, Mallick S
Clin Exp Med 2021 May;21(2):315-321. Epub 2021 Jan 22 doi: 10.1007/s10238-021-00683-2. PMID: 33481141
Management of intermediate-grade lymphomas.
Miller TP
Oncology (Williston Park) 1998 Oct;12(10 Suppl 8):35-9. PMID: 9830631
Follicular and diffuse mixed small-cleaved and large-cell lymphoma--a clinicopathologic study.
Hu E, Weiss LM, Hoppe RT, Horning SJ
J Clin Oncol 1985 Sep;3(9):1183-7. doi: 10.1200/JCO.1985.3.9.1183. PMID: 3897469

Diagnosis

A retrospective histopathological survey on canine lymphomas subtypes of Porto District.
Pinello K, Santos M, Dias-Pereira P, Niza-Ribeiro J, de-Matos A
Open Vet J 2023 Apr;13(4):443-450. Epub 2023 Apr 13 doi: 10.5455/OVJ.2023.v13.i4.6. PMID: 37251261Free PMC Article
Anaplastic diffuse large B-cell lymphoma cytologically diagnosed in pleural effusion: Report of two cases.
AbdullGaffar B, Seliem R
Diagn Cytopathol 2021 Aug;49(8):E307-E311. Epub 2021 Feb 25 doi: 10.1002/dc.24730. PMID: 33629814
Lymphoma subtypes in India: a tertiary care center review.
Jain S, Lone MR, Goswami A, Mandal T, Panda AK, Ramteke P, Srivastav T, Sharma MC, Gogia A, Sharma A, Bakhshi S, Mahapatra M, Kumar L, Mallick S
Clin Exp Med 2021 May;21(2):315-321. Epub 2021 Jan 22 doi: 10.1007/s10238-021-00683-2. PMID: 33481141
Coherent view of non-Hodgkin's lymphoma.
Aisenberg AC
J Clin Oncol 1995 Oct;13(10):2656-75. doi: 10.1200/JCO.1995.13.10.2656. PMID: 7595720
Identification of genetic lesions associated with diffuse large-cell lymphoma.
Dalla-Favera R, Ye BH, Lo Coco F, Gaidano G, Lista F, Knowles DM, Louie DC, Offit K, Chaganti RS
Ann Oncol 1994;5 Suppl 1:55-60. doi: 10.1093/annonc/5.suppl_1.s55. PMID: 8172819

Therapy

Clinical efficacy and safety in relapsed/refractory diffuse large B-cell lymphoma: a systematic literature review.
Colosia A, Njue A, Trask PC, Olivares R, Khan S, Abbe A, Police R, Wang J, Ruiz-Soto R, Kaye JA, Awan F
Clin Lymphoma Myeloma Leuk 2014 Oct;14(5):343-355.e6. Epub 2014 Mar 1 doi: 10.1016/j.clml.2014.02.012. PMID: 24768510
Management of intermediate-grade lymphomas.
Miller TP
Oncology (Williston Park) 1998 Oct;12(10 Suppl 8):35-9. PMID: 9830631
Follicular and diffuse mixed small-cleaved and large-cell lymphoma--a clinicopathologic study.
Hu E, Weiss LM, Hoppe RT, Horning SJ
J Clin Oncol 1985 Sep;3(9):1183-7. doi: 10.1200/JCO.1985.3.9.1183. PMID: 3897469
The role of radiation therapy in the management of the non-Hodgkin's lymphomas.
Hoppe RT
Cancer 1985 May 1;55(9 Suppl):2176-83. doi: 10.1002/1097-0142(19850501)55:9+<2176::aid-cncr2820551421>3.0.co;2-l. PMID: 2579725
Malignant lymphoma, diffuse mixed small and large cell. A clinicopathologic study of 47 cases.
Foucar K, Armitage JO, Dick FR
Cancer 1983 Jun 1;51(11):2090-9. doi: 10.1002/1097-0142(19830601)51:11<2090::aid-cncr2820511123>3.0.co;2-g. PMID: 6687699

Prognosis

Human immunodeficiency virus-associated lymphoma.
Parekh S, Ratech H, Sparano JA
Clin Adv Hematol Oncol 2003 May;1(5):295-301. PMID: 16224426
Management of intermediate-grade lymphomas.
Miller TP
Oncology (Williston Park) 1998 Oct;12(10 Suppl 8):35-9. PMID: 9830631
Identification of genetic lesions associated with diffuse large-cell lymphoma.
Dalla-Favera R, Ye BH, Lo Coco F, Gaidano G, Lista F, Knowles DM, Louie DC, Offit K, Chaganti RS
Ann Oncol 1994;5 Suppl 1:55-60. doi: 10.1093/annonc/5.suppl_1.s55. PMID: 8172819
Follicular and diffuse mixed small-cleaved and large-cell lymphoma--a clinicopathologic study.
Hu E, Weiss LM, Hoppe RT, Horning SJ
J Clin Oncol 1985 Sep;3(9):1183-7. doi: 10.1200/JCO.1985.3.9.1183. PMID: 3897469
The role of radiation therapy in the management of the non-Hodgkin's lymphomas.
Hoppe RT
Cancer 1985 May 1;55(9 Suppl):2176-83. doi: 10.1002/1097-0142(19850501)55:9+<2176::aid-cncr2820551421>3.0.co;2-l. PMID: 2579725

Clinical prediction guides

HCV-associated B-cell non-Hodgkin lymphomas and new direct antiviral agents.
Carrier P, Jaccard A, Jacques J, Tabouret T, Debette-Gratien M, Abraham J, Mesturoux L, Marquet P, Alain S, Sautereau D, Essig M, Loustaud-Ratti V
Liver Int 2015 Oct;35(10):2222-7. Epub 2015 Jul 15 doi: 10.1111/liv.12897. PMID: 26104059
Mixed cryoglobulinemia: demographic, clinical, and serologic features and survival in 231 patients.
Ferri C, Sebastiani M, Giuggioli D, Cazzato M, Longombardo G, Antonelli A, Puccini R, Michelassi C, Zignego AL
Semin Arthritis Rheum 2004 Jun;33(6):355-74. doi: 10.1016/j.semarthrit.2003.10.001. PMID: 15190522
Immunologic markers in non-Hodgkin's lymphoma.
Freedman AS, Nadler LM
Hematol Oncol Clin North Am 1991 Oct;5(5):871-89. PMID: 1938759
Diffuse large cell lymphoma with discordant bone marrow histology. Clinical features and biological implications.
Fisher DE, Jacobson JO, Ault KA, Harris NL
Cancer 1989 Nov 1;64(9):1879-87. doi: 10.1002/1097-0142(19891101)64:9<1879::aid-cncr2820640921>3.0.co;2-d. PMID: 2790699
Chromosomal abnormalities in indolent lymphoma.
Speaks SL, Sanger WG, Linder J, Johnson DR, Armitage JO, Weisenburger D, Purtilo D
Cancer Genet Cytogenet 1987 Aug;27(2):335-44. doi: 10.1016/0165-4608(87)90016-1. PMID: 3297304

Recent systematic reviews

Clinical efficacy and safety in relapsed/refractory diffuse large B-cell lymphoma: a systematic literature review.
Colosia A, Njue A, Trask PC, Olivares R, Khan S, Abbe A, Police R, Wang J, Ruiz-Soto R, Kaye JA, Awan F
Clin Lymphoma Myeloma Leuk 2014 Oct;14(5):343-355.e6. Epub 2014 Mar 1 doi: 10.1016/j.clml.2014.02.012. PMID: 24768510

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