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Malignant Odontogenic Neoplasm

MedGen UID:
83165
Concept ID:
C0334558
Neoplastic Process
Synonyms: Carcinoma arising in an odontogenic cyst; Malignant odontogenic tumor; Malignant Odontogenic Tumor; Odontogenic carcinoma; Odontogenic tumor, malignant
SNOMED CT: Malignant odontogenic tumor (26888009); Odontogenic tumor, malignant (26888009); Odontogenic carcinoma (26888009); Carcinoma arising in an odontogenic cyst (26888009)

Definition

A rare neoplasm arising from tooth-forming tissues. It occurs in the maxillofacial skeleton or the gingiva. Symptoms include swelling, pain, bleeding, mobility of affected teeth, and oral mucosa ulcerations. It may metastasize to lymph nodes and distant anatomic sites early. [from NCI]

Professional guidelines

PubMed

Winters R, Garip M, Meeus J, Coropciuc R, Politis C
Br J Oral Maxillofac Surg 2023 Jun;61(5):331-336. Epub 2023 Apr 25 doi: 10.1016/j.bjoms.2023.04.006. PMID: 37248124
McLean AC, Vargas PA
Head Neck Pathol 2023 Mar;17(1):85-98. Epub 2023 Mar 16 doi: 10.1007/s12105-023-01525-1. PMID: 36928736Free PMC Article
Effiom OA, Ogundana OM, Akinshipo AO, Akintoye SO
Oral Dis 2018 Apr;24(3):307-316. Epub 2017 Mar 9 doi: 10.1111/odi.12646. PMID: 28142213

Recent clinical studies

Etiology

Soyele OO, Adebiyi KE, Adesina OM, Ladeji AM, Aborisade A, Olatunji A, Adeola HA
Pan Afr Med J 2018;31:208. Epub 2018 Nov 27 doi: 10.11604/pamj.2018.31.208.14660. PMID: 31497184Free PMC Article

Diagnosis

Nakhla MN, Richards PQ, Miller JE, Afework D, Manzoor D, Lin YL, Aghaloo T, Blackwell KE, St John MA
Laryngoscope 2023 Apr;133(4):830-833. Epub 2022 Dec 19 doi: 10.1002/lary.30521. PMID: 36533581
Panda S, Das R, Mohapatra D, Mohanty N
BMJ Case Rep 2021 Dec 14;14(12) doi: 10.1136/bcr-2021-246907. PMID: 34906959Free PMC Article
Soyele OO, Adebiyi KE, Adesina OM, Ladeji AM, Aborisade A, Olatunji A, Adeola HA
Pan Afr Med J 2018;31:208. Epub 2018 Nov 27 doi: 10.11604/pamj.2018.31.208.14660. PMID: 31497184Free PMC Article
Casaroto AR, Toledo GL, Filho JL, Soares CT, Capelari MM, Lara VS
Anticancer Res 2012 Apr;32(4):1515-25. PMID: 22493395
Angiero F, Borloni R, Macchi M, Stefani M
Anticancer Res 2008 Nov-Dec;28(6B):3847-54. PMID: 19192639

Prognosis

Yiannis C, Mascolo M, Mignogna MD, Varricchio S, Natella V, De Rosa G, Lo Giudice R, Galletti C, Paolini R, Celentano A
Int J Environ Res Public Health 2021 Apr 8;18(8) doi: 10.3390/ijerph18083899. PMID: 33917771Free PMC Article
Casaroto AR, Toledo GL, Filho JL, Soares CT, Capelari MM, Lara VS
Anticancer Res 2012 Apr;32(4):1515-25. PMID: 22493395

Clinical prediction guides

Yiannis C, Mascolo M, Mignogna MD, Varricchio S, Natella V, De Rosa G, Lo Giudice R, Galletti C, Paolini R, Celentano A
Int J Environ Res Public Health 2021 Apr 8;18(8) doi: 10.3390/ijerph18083899. PMID: 33917771Free PMC Article

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