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Sclerosing stromal tumor

MedGen UID:
569659
•Concept ID:
C0334400
•
Neoplastic Process
SNOMED CT: Sclerosing stromal tumor (64512009)

Professional guidelines

PubMed

Thecoma of the ovary: a report of 70 cases emphasizing aspects of its histopathology different from those often portrayed and its differential diagnosis.
Burandt E, Young RH
Am J Surg Pathol 2014 Aug;38(8):1023-32. doi: 10.1097/PAS.0000000000000252. PMID: 25025365
Ovarian spindle cell lesions: a review with emphasis on recent developments and differential diagnosis.
Irving JA, McCluggage WG
Adv Anat Pathol 2007 Sep;14(5):305-19. doi: 10.1097/PAP.0b013e3180ca8a5b. PMID: 17717430
CT and MR imaging of ovarian tumors with emphasis on differential diagnosis.
Jung SE, Lee JM, Rha SE, Byun JY, Jung JI, Hahn ST
Radiographics 2002 Nov-Dec;22(6):1305-25. doi: 10.1148/rg.226025033. PMID: 12432104

Recent clinical studies

Etiology

The detailed histopathological characteristics of ovarian fibroma compared with thecoma, granulosa cell tumor, and sclerosing stromal tumor.
Mobarki M, Papoudou-Bai A, Musawi S, Péoc'h M, Karpathiou G
Pathol Res Pract 2024 Apr;256:155236. Epub 2024 Mar 2 doi: 10.1016/j.prp.2024.155236. PMID: 38447489
Imaging characteristics of ovarian sclerosing stromal tumor.
Zhou Z, Chen X, Zeng Z, Zhang F, Yan J, Hou G
BMC Womens Health 2022 Sep 1;22(1):362. doi: 10.1186/s12905-022-01949-x. PMID: 36050720Free PMC Article
Ovarian Sex Cord-Stromal Tumors: Reflections on a 40-Year Experience With a Fascinating Group of Tumors, Including Comments on the Seminal Observations of Robert E. Scully, MD.
Young RH
Arch Pathol Lab Med 2018 Dec;142(12):1459-1484. doi: 10.5858/arpa.2018-0291-RA. PMID: 30500284
Ovarian spindle cell lesions: a review with emphasis on recent developments and differential diagnosis.
Irving JA, McCluggage WG
Adv Anat Pathol 2007 Sep;14(5):305-19. doi: 10.1097/PAP.0b013e3180ca8a5b. PMID: 17717430
Sclerosing stromal tumor of the ovary: MR-pathologic correlation in three cases.
Kim JY, Jung KJ, Chung DS, Kim OD, Lee JH, Youn SK
Korean J Radiol 2003 Jul-Sep;4(3):194-9. doi: 10.3348/kjr.2003.4.3.194. PMID: 14530650Free PMC Article

Diagnosis

Sclerosis in Sex Cord-Stromal Tumors Other Than the Sclerosing Stromal Tumor: A Report of 70 Cases.
Devins KM, Young RH
Am J Surg Pathol 2023 Jul 1;47(7):774-784. Epub 2023 May 15 doi: 10.1097/PAS.0000000000002049. PMID: 37184091
Imaging characteristics of ovarian sclerosing stromal tumor.
Zhou Z, Chen X, Zeng Z, Zhang F, Yan J, Hou G
BMC Womens Health 2022 Sep 1;22(1):362. doi: 10.1186/s12905-022-01949-x. PMID: 36050720Free PMC Article
Clinicopathological Characteristics of Ovarian Sclerosing Stromal Tumor with an Emphasis on TFE3 Overexpression.
Park CK, Kim HS
Anticancer Res 2017 Oct;37(10):5441-5447. doi: 10.21873/anticanres.11972. PMID: 28982854
CT and MR imaging of ovarian tumors with emphasis on differential diagnosis.
Jung SE, Lee JM, Rha SE, Byun JY, Jung JI, Hahn ST
Radiographics 2002 Nov-Dec;22(6):1305-25. doi: 10.1148/rg.226025033. PMID: 12432104
Sclerosing stromal tumor of the ovary. Report of eight cases and review of the literature.
Marelli G, Carinelli S, Mariani A, Frigerio L, Ferrari A
Eur J Obstet Gynecol Reprod Biol 1998 Jan;76(1):85-9. doi: 10.1016/s0301-2115(97)00151-6. PMID: 9481554

Therapy

Diversity of imaging features of ovarian sclerosing stromal tumors on MRI and PET-CT: a case report and literature review.
Matsutani H, Nakai G, Yamada T, Yamamoto K, Ohmichi M, Narumi Y
J Ovarian Res 2018 Dec 20;11(1):101. doi: 10.1186/s13048-018-0473-1. PMID: 30572921Free PMC Article
Clinicopathological Characteristics of Ovarian Sclerosing Stromal Tumor with an Emphasis on TFE3 Overexpression.
Park CK, Kim HS
Anticancer Res 2017 Oct;37(10):5441-5447. doi: 10.21873/anticanres.11972. PMID: 28982854
Sex cord stromal tumors of the ovary in children: a clinicopathological report from the Italian TREP project.
Cecchetto G, Ferrari A, Bernini G, Alaggio R, Collini P, Virgone C, Terenziani M, Dall'igna P, Cozza R, Conte M, Bisogno G
Pediatr Blood Cancer 2011 Jul 1;56(7):1062-7. Epub 2010 Dec 15 doi: 10.1002/pbc.22918. PMID: 21488154
Ovarian fibrothecoma with massive edema.
Sakaki M, Hirokawa M, Horiguchi H, Wakatsuki S, Sano T, Izumi Y
J Med Invest 2000 Aug;47(3-4):148-51. PMID: 11019495
Sclerosing stromal tumor of the ovary.
Ho Yuen B, Robertson DI, Clement PB, Mincey EK
Obstet Gynecol 1982 Aug;60(2):252-6. PMID: 7155488

Prognosis

Imaging characteristics of ovarian sclerosing stromal tumor.
Zhou Z, Chen X, Zeng Z, Zhang F, Yan J, Hou G
BMC Womens Health 2022 Sep 1;22(1):362. doi: 10.1186/s12905-022-01949-x. PMID: 36050720Free PMC Article
Juvenile Granulosa Cell Tumors of the Ovary.
Ye Y, Lv C, Xu S, Chen Y, Qian R, Wang P, Wang S
Am J Clin Pathol 2020 Oct 13;154(5):635-644. doi: 10.1093/ajcp/aqaa081. PMID: 32561911
Sex cord stromal tumors of the ovary in children: a clinicopathological report from the Italian TREP project.
Cecchetto G, Ferrari A, Bernini G, Alaggio R, Collini P, Virgone C, Terenziani M, Dall'igna P, Cozza R, Conte M, Bisogno G
Pediatr Blood Cancer 2011 Jul 1;56(7):1062-7. Epub 2010 Dec 15 doi: 10.1002/pbc.22918. PMID: 21488154
Sclerosing stromal tumor of the ovary with elevated CA125.
Terauchi F, Onodera T, Nagashima T, Kobayashi Y, Moritake T, Oharaseki T, Ogura H
J Obstet Gynaecol Res 2005 Oct;31(5):432-5. doi: 10.1111/j.1447-0756.2005.00315.x. PMID: 16176513
Sclerosing stromal tumor of the ovary associated with Meigs' syndrome: a case report.
Bildirici K, Yalçin OT, Ozalp SS, Peker B, Ozden H
Eur J Gynaecol Oncol 2004;25(4):528-9. PMID: 15285324

Clinical prediction guides

Imaging characteristics of ovarian sclerosing stromal tumor.
Zhou Z, Chen X, Zeng Z, Zhang F, Yan J, Hou G
BMC Womens Health 2022 Sep 1;22(1):362. doi: 10.1186/s12905-022-01949-x. PMID: 36050720Free PMC Article
Juvenile Granulosa Cell Tumors of the Ovary.
Ye Y, Lv C, Xu S, Chen Y, Qian R, Wang P, Wang S
Am J Clin Pathol 2020 Oct 13;154(5):635-644. doi: 10.1093/ajcp/aqaa081. PMID: 32561911
Ovarian Sex Cord-Stromal Tumors: Reflections on a 40-Year Experience With a Fascinating Group of Tumors, Including Comments on the Seminal Observations of Robert E. Scully, MD.
Young RH
Arch Pathol Lab Med 2018 Dec;142(12):1459-1484. doi: 10.5858/arpa.2018-0291-RA. PMID: 30500284
On the pathogenesis of sclerosing stromal tumor of the ovary: a neoplasm in transition.
Roth LM, Gaba AR, Cheng L
Int J Gynecol Pathol 2014 Sep;33(5):449-62. doi: 10.1097/PGP.0000000000000084. PMID: 25083960
Sclerosing stromal tumor and bilateral teratomas: an unusual association.
Valente PT, Carr RF, Hanjani P
Gynecol Oncol 1985 Jun;21(2):252-9. doi: 10.1016/0090-8258(85)90261-6. PMID: 3988140

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