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Myelomalacia

MedGen UID:
542982
•Concept ID:
C0270774
•
Disease or Syndrome
SNOMED CT: Myelomalacia (33772003)

Professional guidelines

PubMed

Clinical utility of optimized three-dimensional T1-, T2-, and T2*-weighted sequences in spinal magnetic resonance imaging.
Tanitame N, Tanitame K, Awai K
Jpn J Radiol 2017 Apr;35(4):135-144. Epub 2017 Feb 23 doi: 10.1007/s11604-017-0621-3. PMID: 28233194
Surgical treatment of syringomyelia based on magnetic resonance imaging criteria.
Milhorat TH, Johnson WD, Miller JI, Bergland RM, Hollenberg-Sher J
Neurosurgery 1992 Aug;31(2):231-44; discussion 244-5. doi: 10.1227/00006123-199208000-00008. PMID: 1513429

Recent clinical studies

Etiology

An Assessment of the Effectiveness of Surgical Treatment Methods Used for Cervical Spondylosis.
Somay H, Bolukbasi BA, Karaarslan N, Berkman MZ
Turk Neurosurg 2022;32(2):261-270. doi: 10.5137/1019-5149.JTN.33981-21.2. PMID: 34859830
C5 palsy following posterior decompression and instrumentation in cervical stenosis: Single center experience and review.
Hitchon PW, Moritani T, Woodroffe RW, Abode-Iyamah K, El Tecle NE, Noeller J, Elwy RK, Nourski KV
Clin Neurol Neurosurg 2018 Nov;174:29-35. Epub 2018 Aug 22 doi: 10.1016/j.clineuro.2018.08.028. PMID: 30195898
Tuberculosis of spine: neurological deficit.
Jain AK, Kumar J
Eur Spine J 2013 Jun;22 Suppl 4(Suppl 4):624-33. Epub 2012 May 8 doi: 10.1007/s00586-012-2335-7. PMID: 22565802Free PMC Article
Syringomyelia and arachnoiditis.
Caplan LR, Norohna AB, Amico LL
J Neurol Neurosurg Psychiatry 1990 Feb;53(2):106-13. doi: 10.1136/jnnp.53.2.106. PMID: 2313296Free PMC Article
MR imaging of compressive myelomalacia.
Ramanauskas WL, Wilner HI, Metes JJ, Lazo A, Kelly JK
J Comput Assist Tomogr 1989 May-Jun;13(3):399-404. doi: 10.1097/00004728-198905000-00005. PMID: 2723169

Diagnosis

How Should Syringomyelia be Defined and Diagnosed?
Klekamp J
World Neurosurg 2018 Mar;111:e729-e745. Epub 2018 Jan 6 doi: 10.1016/j.wneu.2017.12.156. PMID: 29317358
Cerebral palsy lifetime care - four musculoskeletal conditions.
Murphy KP
Dev Med Child Neurol 2009 Oct;51 Suppl 4:30-7. doi: 10.1111/j.1469-8749.2009.03431.x. PMID: 19740208
Tuberculosis of the spine: a review.
Jain AK, Dhammi IK
Clin Orthop Relat Res 2007 Jul;460:39-49. doi: 10.1097/BLO.0b013e318065b7c3. PMID: 17438468
Diffuse idiopathic skeletal hyperostosis.
Cammisa M, De Serio A, Guglielmi G
Eur J Radiol 1998 May;27 Suppl 1:S7-11. doi: 10.1016/s0720-048x(98)00036-9. PMID: 9652495
MR imaging of compressive myelomalacia.
Ramanauskas WL, Wilner HI, Metes JJ, Lazo A, Kelly JK
J Comput Assist Tomogr 1989 May-Jun;13(3):399-404. doi: 10.1097/00004728-198905000-00005. PMID: 2723169

Therapy

Bilateral phrenic nerve palsy after posterior cervical decompression and fusion surgery: a rare event after surgery.
Gonzalez GA, Miao J, Porto G, Harrop J
Spinal Cord Ser Cases 2023 Aug 12;9(1):41. doi: 10.1038/s41394-023-00595-1. PMID: 37573432Free PMC Article
Indicators for Substantial Neurological Recovery Following Elective Anterior Cervical Discectomy and Fusion.
Pinter ZW, Sebastian AS, Wagner SC, Morrissey PB, Kaye ID, Hilibrand AS, Vaccaro A, Kepler C
Clin Spine Surg 2022 Nov 1;35(9):E698-E701. Epub 2022 May 9 doi: 10.1097/BSD.0000000000001340. PMID: 35552290
An Assessment of the Effectiveness of Surgical Treatment Methods Used for Cervical Spondylosis.
Somay H, Bolukbasi BA, Karaarslan N, Berkman MZ
Turk Neurosurg 2022;32(2):261-270. doi: 10.5137/1019-5149.JTN.33981-21.2. PMID: 34859830
C5 palsy following posterior decompression and instrumentation in cervical stenosis: Single center experience and review.
Hitchon PW, Moritani T, Woodroffe RW, Abode-Iyamah K, El Tecle NE, Noeller J, Elwy RK, Nourski KV
Clin Neurol Neurosurg 2018 Nov;174:29-35. Epub 2018 Aug 22 doi: 10.1016/j.clineuro.2018.08.028. PMID: 30195898
A Rare Complication of Tuberculosis: Acute Paraplegia.
Aydın T, Taşpınar Ö, Keskin Y, Kepekçi M, Güneşer M, Çamlı A, Seyithanoğlu H, Kızıltan H, Eriş AH
Ethiop J Health Sci 2016 Jul;26(4):405-7. doi: 10.4314/ejhs.v26i4.14. PMID: 27587940Free PMC Article

Prognosis

A Rare Neonatal Intramedullary Immature Teratoma Undiagnosed in utero: A Case Report.
Kahn M, Iacob S, Bach SE, Russell T, Avellino AM, Lin JJ
Pediatr Neurosurg 2022;57(1):50-55. Epub 2021 Nov 2 doi: 10.1159/000519768. PMID: 34727552
C5 palsy following posterior decompression and instrumentation in cervical stenosis: Single center experience and review.
Hitchon PW, Moritani T, Woodroffe RW, Abode-Iyamah K, El Tecle NE, Noeller J, Elwy RK, Nourski KV
Clin Neurol Neurosurg 2018 Nov;174:29-35. Epub 2018 Aug 22 doi: 10.1016/j.clineuro.2018.08.028. PMID: 30195898
Tuberculosis of spine: neurological deficit.
Jain AK, Kumar J
Eur Spine J 2013 Jun;22 Suppl 4(Suppl 4):624-33. Epub 2012 May 8 doi: 10.1007/s00586-012-2335-7. PMID: 22565802Free PMC Article
Tuberculosis of the spine: a review.
Jain AK, Dhammi IK
Clin Orthop Relat Res 2007 Jul;460:39-49. doi: 10.1097/BLO.0b013e318065b7c3. PMID: 17438468
Syringomyelia and arachnoiditis.
Caplan LR, Norohna AB, Amico LL
J Neurol Neurosurg Psychiatry 1990 Feb;53(2):106-13. doi: 10.1136/jnnp.53.2.106. PMID: 2313296Free PMC Article

Clinical prediction guides

An Assessment of the Effectiveness of Surgical Treatment Methods Used for Cervical Spondylosis.
Somay H, Bolukbasi BA, Karaarslan N, Berkman MZ
Turk Neurosurg 2022;32(2):261-270. doi: 10.5137/1019-5149.JTN.33981-21.2. PMID: 34859830
C5 palsy following posterior decompression and instrumentation in cervical stenosis: Single center experience and review.
Hitchon PW, Moritani T, Woodroffe RW, Abode-Iyamah K, El Tecle NE, Noeller J, Elwy RK, Nourski KV
Clin Neurol Neurosurg 2018 Nov;174:29-35. Epub 2018 Aug 22 doi: 10.1016/j.clineuro.2018.08.028. PMID: 30195898
Thoracic disc herniation and acute myelopathy: clinical presentation, neuroimaging findings, surgical considerations, and outcome.
Cornips EM, Janssen ML, Beuls EA
J Neurosurg Spine 2011 Apr;14(4):520-8. Epub 2011 Feb 11 doi: 10.3171/2010.12.SPINE10273. PMID: 21314281
Tuberculosis of the spine: a review.
Jain AK, Dhammi IK
Clin Orthop Relat Res 2007 Jul;460:39-49. doi: 10.1097/BLO.0b013e318065b7c3. PMID: 17438468
Profile of non-compressive myelopathy in eastern India: a 2-year study.
Das K, Saha SP, Das SK, Ganguly PK, Roy TN, Maity B
Acta Neurol Scand 1999 Feb;99(2):100-5. doi: 10.1111/j.1600-0404.1999.tb00665.x. PMID: 10071168

Recent systematic reviews

Bibrachial amyotrophy as a rare manifestation of intraspinal fluid collection: a case report and systematic review.
Quattrocchi S, Bonan L, Cirillo L, Avoni P, Di Stasi V, Rizzo G, Liguori R, Vacchiano V
Neurol Sci 2024 May;45(5):2279-2288. Epub 2023 Nov 16 doi: 10.1007/s10072-023-07170-4. PMID: 37968433
Chronic neuropathic pain in spinal cord injured patients: what is the effectiveness of surgical treatments excluding central neurostimulations?
Robert R, Perrouin-Verbe B, Albert T, Bussel B, Hamel O
Ann Phys Rehabil Med 2009 Mar;52(2):194-202. Epub 2009 Feb 23 doi: 10.1016/j.rehab.2008.12.016. PMID: 19909710

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