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Rebound insomnia

MedGen UID:
124357
•Concept ID:
C0270541
•
Sign or Symptom
Synonyms: Insomnia, Rebound; Rebound Insomnia
SNOMED CT: Rebound insomnia (88982005)

Professional guidelines

PubMed

Insomnia Management: A Review and Update.
Shaha DP
J Fam Pract 2023 Jul;72(6 Suppl):S31-S36. doi: 10.12788/jfp.0620. PMID: 37549414
Management of insomnia.
Kirkwood CK
J Am Pharm Assoc (Wash) 1999 Sep-Oct;39(5):688-96; quiz 713-4. doi: 10.1016/s1086-5802(15)30354-5. PMID: 10533351
Insomnia: drug treatment.
Tsoi WF
Ann Acad Med Singap 1991 Mar;20(2):269-72. PMID: 1679317

Recent clinical studies

Etiology

Insomnia Management: A Review and Update.
Shaha DP
J Fam Pract 2023 Jul;72(6 Suppl):S31-S36. doi: 10.12788/jfp.0620. PMID: 37549414
Long-term effectiveness and safety of lemborexant in adults with insomnia disorder: results from a phase 3 randomized clinical trial.
Yardley J, Kärppä M, Inoue Y, Pinner K, Perdomo C, Ishikawa K, Filippov G, Kubota N, Moline M
Sleep Med 2021 Apr;80:333-342. Epub 2021 Feb 1 doi: 10.1016/j.sleep.2021.01.048. PMID: 33636648
Hypnotics in insomnia: the experience of zolpidem.
MacFarlane J, Morin CM, Montplaisir J
Clin Ther 2014 Nov 1;36(11):1676-701. Epub 2014 Nov 19 doi: 10.1016/j.clinthera.2014.09.017. PMID: 25455931
Zolpidem for insomnia.
Greenblatt DJ, Roth T
Expert Opin Pharmacother 2012 Apr;13(6):879-93. Epub 2012 Mar 19 doi: 10.1517/14656566.2012.667074. PMID: 22424586
An assessment of short-acting hypnotics.
Mendelson WB, Jain B
Drug Saf 1995 Oct;13(4):257-70. doi: 10.2165/00002018-199513040-00005. PMID: 8573298

Diagnosis

Insomnia Management: A Review and Update.
Shaha DP
J Fam Pract 2023 Jul;72(6 Suppl):S31-S36. doi: 10.12788/jfp.0620. PMID: 37549414
Drugs for Insomnia beyond Benzodiazepines: Pharmacology, Clinical Applications, and Discovery.
Atkin T, Comai S, Gobbi G
Pharmacol Rev 2018 Apr;70(2):197-245. doi: 10.1124/pr.117.014381. PMID: 29487083
Intermittent and long-term use of sedative hypnotics.
Perlis M, Gehrman P, Riemann D
Curr Pharm Des 2008;14(32):3456-65. doi: 10.2174/138161208786549290. PMID: 19075721
Insomnia.
Epstein DR, Bootzin RR
Nurs Clin North Am 2002 Dec;37(4):611-31. doi: 10.1016/s0029-6465(02)00028-2. PMID: 12587364
Insomnia in the elderly: a review for the primary care practitioner.
Ancoli-Israel S
Sleep 2000 Feb 1;23 Suppl 1:S23-30; discussion S36-8. PMID: 10755805

Therapy

Long-term effectiveness and safety of lemborexant in adults with insomnia disorder: results from a phase 3 randomized clinical trial.
Yardley J, Kärppä M, Inoue Y, Pinner K, Perdomo C, Ishikawa K, Filippov G, Kubota N, Moline M
Sleep Med 2021 Apr;80:333-342. Epub 2021 Feb 1 doi: 10.1016/j.sleep.2021.01.048. PMID: 33636648
Hypnotic Discontinuation in Chronic Insomnia.
Hintze JP, Edinger JD
Sleep Med Clin 2020 Jun;15(2):147-154. doi: 10.1016/j.jsmc.2020.02.003. PMID: 32386690
Hypnotic Discontinuation in Chronic Insomnia.
Hintze JP, Edinger JD
Sleep Med Clin 2018 Jun;13(2):263-270. doi: 10.1016/j.jsmc.2018.02.008. PMID: 29759276
Drugs for Insomnia beyond Benzodiazepines: Pharmacology, Clinical Applications, and Discovery.
Atkin T, Comai S, Gobbi G
Pharmacol Rev 2018 Apr;70(2):197-245. doi: 10.1124/pr.117.014381. PMID: 29487083
Zolpidem for insomnia.
Greenblatt DJ, Roth T
Expert Opin Pharmacother 2012 Apr;13(6):879-93. Epub 2012 Mar 19 doi: 10.1517/14656566.2012.667074. PMID: 22424586

Prognosis

Gender Differences in the Efficacy and Safety of Chronic Nightly Zolpidem.
Roehrs TA, Roth T
J Clin Sleep Med 2016 Mar;12(3):319-25. doi: 10.5664/jcsm.5574. PMID: 26446253Free PMC Article
Anxiety or depression during withdrawal of hypnotic treatments.
Lader M
J Psychosom Res 1994;38 Suppl 1:113-23; discussion 118-23. doi: 10.1016/0022-3999(94)90142-2. PMID: 7799243
Comparative clinical profiles of triazolam versus other shorter-acting hypnotics.
Jonas JM, Coleman BS, Sheridan AQ, Kalinske RW
J Clin Psychiatry 1992 Dec;53 Suppl:19-31; discussion 32-3. PMID: 1336776
Rebound insomnia: its determinants and significance.
Roehrs T, Vogel G, Roth T
Am J Med 1990 Mar 2;88(3A):39S-42S. doi: 10.1016/s0002-9343(13)80001-0. PMID: 1968719
Multiple-dose quazepam kinetics.
Chung M, Hilbert JM, Gural RP, Radwanski E, Symchowicz S, Zampaglione N
Clin Pharmacol Ther 1984 Apr;35(4):520-4. doi: 10.1038/clpt.1984.70. PMID: 6705450

Clinical prediction guides

Long-term effectiveness and safety of lemborexant in adults with insomnia disorder: results from a phase 3 randomized clinical trial.
Yardley J, Kärppä M, Inoue Y, Pinner K, Perdomo C, Ishikawa K, Filippov G, Kubota N, Moline M
Sleep Med 2021 Apr;80:333-342. Epub 2021 Feb 1 doi: 10.1016/j.sleep.2021.01.048. PMID: 33636648
Zolpidem for insomnia.
Greenblatt DJ, Roth T
Expert Opin Pharmacother 2012 Apr;13(6):879-93. Epub 2012 Mar 19 doi: 10.1517/14656566.2012.667074. PMID: 22424586
Eszopiclone for insomnia.
Melton ST, Wood JM, Kirkwood CK
Ann Pharmacother 2005 Oct;39(10):1659-66. Epub 2005 Aug 30 doi: 10.1345/aph.1G179. PMID: 16131537
Rebound insomnia: its determinants and significance.
Roehrs T, Vogel G, Roth T
Am J Med 1990 Mar 2;88(3A):39S-42S. doi: 10.1016/s0002-9343(13)80001-0. PMID: 1968719
Multiple-dose quazepam kinetics.
Chung M, Hilbert JM, Gural RP, Radwanski E, Symchowicz S, Zampaglione N
Clin Pharmacol Ther 1984 Apr;35(4):520-4. doi: 10.1038/clpt.1984.70. PMID: 6705450

Recent systematic reviews

Suvorexant for Primary Insomnia: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.
Kishi T, Matsunaga S, Iwata N
PLoS One 2015;10(8):e0136910. Epub 2015 Aug 28 doi: 10.1371/journal.pone.0136910. PMID: 26317363Free PMC Article
Suvorexant for insomnia: a systematic review of the efficacy and safety profile for this newly approved hypnotic - what is the number needed to treat, number needed to harm and likelihood to be helped or harmed?
Citrome L
Int J Clin Pract 2014 Dec;68(12):1429-41. Epub 2014 Sep 18 doi: 10.1111/ijcp.12568. PMID: 25231363
Intermittent and long-term use of sedative hypnotics.
Perlis M, Gehrman P, Riemann D
Curr Pharm Des 2008;14(32):3456-65. doi: 10.2174/138161208786549290. PMID: 19075721
Comparative efficacy of newer hypnotic drugs for the short-term management of insomnia: a systematic review and meta-analysis.
Dündar Y, Dodd S, Strobl J, Boland A, Dickson R, Walley T
Hum Psychopharmacol 2004 Jul;19(5):305-22. doi: 10.1002/hup.594. PMID: 15252823
Newer hypnotic drugs for the short-term management of insomnia: a systematic review and economic evaluation.
Dündar Y, Boland A, Strobl J, Dodd S, Haycox A, Bagust A, Bogg J, Dickson R, Walley T
Health Technol Assess 2004 Jun;8(24):iii-x, 1-125. doi: 10.3310/hta8240. PMID: 15193209

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