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Descending perineum syndrome

MedGen UID:
540811
•Concept ID:
C0267602
•
Disease or Syndrome
SNOMED CT: Descending perineum syndrome (70441009)

Professional guidelines

PubMed

The role of GSTM1 gene polymorphism in pathophysiology, evaluation, and management of constipation of anorectal outlet obstruction.
Wang S, Fan Z
Cell Mol Biol (Noisy-le-grand) 2021 Nov 25;67(3):163-167. doi: 10.14715/cmb/2021.67.3.25. PMID: 34933715
Descending perineum syndrome: a review of the presentation, diagnosis, and management.
Chaudhry Z, Tarnay C
Int Urogynecol J 2016 Aug;27(8):1149-56. Epub 2016 Jan 11 doi: 10.1007/s00192-015-2889-0. PMID: 26755058
Constipation of anorectal outlet obstruction: pathophysiology, evaluation and management.
Andromanakos N, Skandalakis P, Troupis T, Filippou D
J Gastroenterol Hepatol 2006 Apr;21(4):638-46. doi: 10.1111/j.1440-1746.2006.04333.x. PMID: 16677147

Recent clinical studies

Etiology

The role of GSTM1 gene polymorphism in pathophysiology, evaluation, and management of constipation of anorectal outlet obstruction.
Wang S, Fan Z
Cell Mol Biol (Noisy-le-grand) 2021 Nov 25;67(3):163-167. doi: 10.14715/cmb/2021.67.3.25. PMID: 34933715
Clinical Features and Associations of Descending Perineum Syndrome in 300 Adults with Constipation in Gastroenterology Referral Practice.
Wang XJ, Chedid V, Vijayvargiya P, Camilleri M
Dig Dis Sci 2020 Dec;65(12):3688-3695. Epub 2020 Jul 14 doi: 10.1007/s10620-020-06394-0. PMID: 32666237Free PMC Article
Defecographic Findings in Patients with Severe Idiopathic Chronic Constipation.
Rafiei R, Bayat A, Taheri M, Torabi Z, Fooladi L, Husaini S
Korean J Gastroenterol 2017 Jul 25;70(1):39-43. doi: 10.4166/kjg.2017.70.1.39. PMID: 28728315
Descending perineum syndrome: are abdominal hysterectomy and bowel habits linked?
Pucciani F, Boni D, Perna F, Bassotti G, Bellini M
Dis Colon Rectum 2005 Nov;48(11):2094-9. doi: 10.1007/s10350-005-0163-0. PMID: 16228840
Descending perineum syndrome: audit of clinical and laboratory features and outcome of pelvic floor retraining.
Harewood GC, Coulie B, Camilleri M, Rath-Harvey D, Pemberton JH
Am J Gastroenterol 1999 Jan;94(1):126-30. doi: 10.1111/j.1572-0241.1999.00782.x. PMID: 9934742

Diagnosis

Refractory Constipation: How to Evaluate and Treat.
Camilleri M, Brandler J
Gastroenterol Clin North Am 2020 Sep;49(3):623-642. Epub 2020 Jun 14 doi: 10.1016/j.gtc.2020.05.002. PMID: 32718574
Endoscopic transperineal pudendal nerve decompression: operative pudendoscopy.
Beco J, Seidel L, Albert A
Surg Endosc 2018 Aug;32(8):3720-3731. Epub 2018 May 23 doi: 10.1007/s00464-018-6239-4. PMID: 29796819
Descending perineum syndrome: a review of the presentation, diagnosis, and management.
Chaudhry Z, Tarnay C
Int Urogynecol J 2016 Aug;27(8):1149-56. Epub 2016 Jan 11 doi: 10.1007/s00192-015-2889-0. PMID: 26755058
Descending perineum syndrome: new perspectives.
Pucciani F
Tech Coloproctol 2015 Aug;19(8):443-8. Epub 2015 Jun 6 doi: 10.1007/s10151-015-1321-6. PMID: 26047661
Operative therapy for anal incontinence.
Schoetz DJ Jr
Surg Clin North Am 1985 Feb;65(1):35-46. doi: 10.1016/s0039-6109(16)43531-0. PMID: 3887619

Therapy

Clinical Features and Associations of Descending Perineum Syndrome in 300 Adults with Constipation in Gastroenterology Referral Practice.
Wang XJ, Chedid V, Vijayvargiya P, Camilleri M
Dig Dis Sci 2020 Dec;65(12):3688-3695. Epub 2020 Jul 14 doi: 10.1007/s10620-020-06394-0. PMID: 32666237Free PMC Article
Behavioural and new pharmacological treatments for constipation: getting the balance right.
Camilleri M, Bharucha AE
Gut 2010 Sep;59(9):1288-96. doi: 10.1136/gut.2009.199653. PMID: 20801775Free PMC Article
Biofeedback for the treatment of fecal incontinence. Long-term clinical results.
Guillemot F, Bouche B, Gower-Rousseau C, Chartier M, Wolschies E, Lamblin MD, Harbonnier E, Cortot A
Dis Colon Rectum 1995 Apr;38(4):393-7. doi: 10.1007/BF02054228. PMID: 7720447

Prognosis

Descending perineum syndrome: audit of clinical and laboratory features and outcome of pelvic floor retraining.
Harewood GC, Coulie B, Camilleri M, Rath-Harvey D, Pemberton JH
Am J Gastroenterol 1999 Jan;94(1):126-30. doi: 10.1111/j.1572-0241.1999.00782.x. PMID: 9934742
Biofeedback for the treatment of fecal incontinence. Long-term clinical results.
Guillemot F, Bouche B, Gower-Rousseau C, Chartier M, Wolschies E, Lamblin MD, Harbonnier E, Cortot A
Dis Colon Rectum 1995 Apr;38(4):393-7. doi: 10.1007/BF02054228. PMID: 7720447
Investigations of the anal sphincter before and after restorative proctocolectomy.
Sharp FR, Bell GA, Seal AM, Atkinson KG
Am J Surg 1987 May;153(5):469-72. doi: 10.1016/0002-9610(87)90795-1. PMID: 3578668

Clinical prediction guides

Endoscopic transperineal pudendal nerve decompression: operative pudendoscopy.
Beco J, Seidel L, Albert A
Surg Endosc 2018 Aug;32(8):3720-3731. Epub 2018 May 23 doi: 10.1007/s00464-018-6239-4. PMID: 29796819
COL1A1 Mutations Presenting as Descending Perineum Syndrome in a Young Patient With Hypermobility Syndrome.
Vijayvargiya P, Camilleri M, Cima RR
Mayo Clin Proc 2018 Mar;93(3):386-391. doi: 10.1016/j.mayocp.2018.01.007. PMID: 29502568
Defecographic Findings in Patients with Severe Idiopathic Chronic Constipation.
Rafiei R, Bayat A, Taheri M, Torabi Z, Fooladi L, Husaini S
Korean J Gastroenterol 2017 Jul 25;70(1):39-43. doi: 10.4166/kjg.2017.70.1.39. PMID: 28728315
Descending perineum syndrome: audit of clinical and laboratory features and outcome of pelvic floor retraining.
Harewood GC, Coulie B, Camilleri M, Rath-Harvey D, Pemberton JH
Am J Gastroenterol 1999 Jan;94(1):126-30. doi: 10.1111/j.1572-0241.1999.00782.x. PMID: 9934742
Investigations of the anal sphincter before and after restorative proctocolectomy.
Sharp FR, Bell GA, Seal AM, Atkinson KG
Am J Surg 1987 May;153(5):469-72. doi: 10.1016/0002-9610(87)90795-1. PMID: 3578668

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