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Cyanotic congenital heart disease

MedGen UID:
539507
•Concept ID:
C0265808
•
Disease or Syndrome
SNOMED CT: Cyanotic congenital heart disease (12770006)

Professional guidelines

PubMed

Cyanotic Congenital Heart Disease in Pregnancy: A Review of Pathophysiology and Management.
Koziol KJ, Isath A, Aronow WS, Frishman W, Ranjan P
Cardiol Rev 2024 Jul-Aug 01;32(4):348-355. Epub 2023 Jan 23 doi: 10.1097/CRD.0000000000000512. PMID: 36716356
Prenatal diagnosis of total anomalous pulmonary venous connection: 2D and 3D echocardiographic findings.
Bravo-Valenzuela NJM, Peixoto AB, Araujo Júnior E
J Clin Ultrasound 2021 Mar;49(3):240-247. Epub 2021 Jan 4 doi: 10.1002/jcu.22973. PMID: 33398887
Management of acute heart failure in adult patients with congenital heart disease.
Van De Bruaene A, Meier L, Droogne W, De Meester P, Troost E, Gewillig M, Budts W
Heart Fail Rev 2018 Jan;23(1):1-14. doi: 10.1007/s10741-017-9664-x. PMID: 29277859

Recent clinical studies

Etiology

High-Risk Congenital Heart Disease in Pregnancy.
Rajpal S, Rodriguez CP
Methodist Debakey Cardiovasc J 2024;20(2):24-35. Epub 2024 Mar 14 doi: 10.14797/mdcvj.1306. PMID: 38495662Free PMC Article
Association of Maternal Prepregnancy Diabetes and Gestational Diabetes Mellitus With Congenital Anomalies of the Newborn.
Wu Y, Liu B, Sun Y, Du Y, Santillan MK, Santillan DA, Snetselaar LG, Bao W
Diabetes Care 2020 Dec;43(12):2983-2990. Epub 2020 Oct 21 doi: 10.2337/dc20-0261. PMID: 33087319Free PMC Article
Long-term Outcomes of Tetralogy of Fallot: A Study From the Pediatric Cardiac Care Consortium.
Smith CA, McCracken C, Thomas AS, Spector LG, St Louis JD, Oster ME, Moller JH, Kochilas L
JAMA Cardiol 2019 Jan 1;4(1):34-41. doi: 10.1001/jamacardio.2018.4255. PMID: 30566184Free PMC Article
Cyanotic Congenital Heart Disease: Essential Primer for the Practicing Radiologist.
Zucker EJ, Koning JL, Lee EY
Radiol Clin North Am 2017 Jul;55(4):693-716. Epub 2017 Apr 6 doi: 10.1016/j.rcl.2017.02.009. PMID: 28601176
Cyanotic congenital heart disease and atherosclerosis.
Tarp JB, Jensen AS, Engstrøm T, Holstein-Rathlou NH, Søndergaard L
Heart 2017 Jun;103(12):897-900. Epub 2017 Mar 4 doi: 10.1136/heartjnl-2016-311012. PMID: 28259844

Diagnosis

High-Risk Congenital Heart Disease in Pregnancy.
Rajpal S, Rodriguez CP
Methodist Debakey Cardiovasc J 2024;20(2):24-35. Epub 2024 Mar 14 doi: 10.14797/mdcvj.1306. PMID: 38495662Free PMC Article
Congenital Cyanotic Heart Disease and the Association with Pheochromocytomas and Paragangliomas.
Jones RB Jr, Cohen DL
Curr Cardiol Rep 2023 Nov;25(11):1451-1460. Epub 2023 Oct 17 doi: 10.1007/s11886-023-01974-8. PMID: 37847359
Current outcomes and treatment of tetralogy of Fallot.
van der Ven JPG, van den Bosch E, Bogers AJCC, Helbing WA
F1000Res 2019;8 Epub 2019 Aug 29 doi: 10.12688/f1000research.17174.1. PMID: 31508203Free PMC Article
Cyanotic Congenital Heart Disease: Essential Primer for the Practicing Radiologist.
Zucker EJ, Koning JL, Lee EY
Radiol Clin North Am 2017 Jul;55(4):693-716. Epub 2017 Apr 6 doi: 10.1016/j.rcl.2017.02.009. PMID: 28601176
Tetralogy of Fallot.
Apitz C, Webb GD, Redington AN
Lancet 2009 Oct 24;374(9699):1462-71. Epub 2009 Aug 14 doi: 10.1016/S0140-6736(09)60657-7. PMID: 19683809

Therapy

Mechanisms of perioperative brain damage in children with congenital heart disease.
Zhu S, Sai X, Lin J, Deng G, Zhao M, Nasser MI, Zhu P
Biomed Pharmacother 2020 Dec;132:110957. Epub 2020 Nov 1 doi: 10.1016/j.biopha.2020.110957. PMID: 33254442
Risk of thromboembolic complications in adult congenital heart disease: A literature review.
Karsenty C, Zhao A, Marijon E, Ladouceur M
Arch Cardiovasc Dis 2018 Oct;111(10):613-620. Epub 2018 May 30 doi: 10.1016/j.acvd.2018.04.003. PMID: 29859704
Approach to a child with bleeding in the emergency room.
Bansal D, Oberoi S, Marwaha RK, Singhi SC
Indian J Pediatr 2013 May;80(5):411-20. Epub 2012 Dec 27 doi: 10.1007/s12098-012-0918-2. PMID: 23269640
Diagnosis and management of cyanotic congenital heart disease: part II.
Syamasundar Rao P
Indian J Pediatr 2009 Mar;76(3):297-308. Epub 2009 Apr 6 doi: 10.1007/s12098-009-0056-7. PMID: 19347670
Cyanotic congenital heart disease: hematologic management.
Territo MC, Rosove MH
J Am Coll Cardiol 1991 Aug;18(2):320-2. doi: 10.1016/0735-1097(91)90572-q. PMID: 1856391

Prognosis

Fetal Hemodynamics, Early Survival, and Neurodevelopment in Patients With Cyanotic Congenital Heart Disease.
Lee FT, Sun L, van Amerom JFP, Portnoy S, Marini D, Saini A, Milligan N, Lim JM, Saini B, Selvanathan T, Kazazian V, Sananes R, Jaeggi E, Kingdom JC, Macgowan CK, Ly L, Chau V, Miller SP, Seed M
J Am Coll Cardiol 2024 Apr 2;83(13):1225-1239. Epub 2024 Mar 25 doi: 10.1016/j.jacc.2024.02.005. PMID: 38538202
Neutrophil-Lymphocyte Ratio in Congenital Heart Surgery: What Is Known and What Is New?
Manuel V, Miana LA, Jatene MB
World J Pediatr Congenit Heart Surg 2022 Mar;13(2):208-216. doi: 10.1177/21501351211064143. PMID: 35238705
Current outcomes and treatment of tetralogy of Fallot.
van der Ven JPG, van den Bosch E, Bogers AJCC, Helbing WA
F1000Res 2019;8 Epub 2019 Aug 29 doi: 10.12688/f1000research.17174.1. PMID: 31508203Free PMC Article
Long-term Outcomes of Tetralogy of Fallot: A Study From the Pediatric Cardiac Care Consortium.
Smith CA, McCracken C, Thomas AS, Spector LG, St Louis JD, Oster ME, Moller JH, Kochilas L
JAMA Cardiol 2019 Jan 1;4(1):34-41. doi: 10.1001/jamacardio.2018.4255. PMID: 30566184Free PMC Article
Tetralogy of Fallot.
Apitz C, Webb GD, Redington AN
Lancet 2009 Oct 24;374(9699):1462-71. Epub 2009 Aug 14 doi: 10.1016/S0140-6736(09)60657-7. PMID: 19683809

Clinical prediction guides

Fetal Hemodynamics, Early Survival, and Neurodevelopment in Patients With Cyanotic Congenital Heart Disease.
Lee FT, Sun L, van Amerom JFP, Portnoy S, Marini D, Saini A, Milligan N, Lim JM, Saini B, Selvanathan T, Kazazian V, Sananes R, Jaeggi E, Kingdom JC, Macgowan CK, Ly L, Chau V, Miller SP, Seed M
J Am Coll Cardiol 2024 Apr 2;83(13):1225-1239. Epub 2024 Mar 25 doi: 10.1016/j.jacc.2024.02.005. PMID: 38538202
Neutrophil-Lymphocyte Ratio in Congenital Heart Surgery: What Is Known and What Is New?
Manuel V, Miana LA, Jatene MB
World J Pediatr Congenit Heart Surg 2022 Mar;13(2):208-216. doi: 10.1177/21501351211064143. PMID: 35238705
Suppression of Myocardial Hypoxia-Inducible Factor-1α Compromises Metabolic Adaptation and Impairs Cardiac Function in Patients With Cyanotic Congenital Heart Disease During Puberty.
Liu Y, Luo Q, Su Z, Xing J, Wu J, Xiang L, Huang Y, Pan H, Wu X, Zhang X, Li J, Yan F, Zhang H
Circulation 2021 Jun 8;143(23):2254-2272. Epub 2021 Mar 5 doi: 10.1161/CIRCULATIONAHA.120.051937. PMID: 33663226
Current outcomes and treatment of tetralogy of Fallot.
van der Ven JPG, van den Bosch E, Bogers AJCC, Helbing WA
F1000Res 2019;8 Epub 2019 Aug 29 doi: 10.12688/f1000research.17174.1. PMID: 31508203Free PMC Article
Risk of thromboembolic complications in adult congenital heart disease: A literature review.
Karsenty C, Zhao A, Marijon E, Ladouceur M
Arch Cardiovasc Dis 2018 Oct;111(10):613-620. Epub 2018 May 30 doi: 10.1016/j.acvd.2018.04.003. PMID: 29859704

Recent systematic reviews

Patent Ductus Arteriosus Stent Versus Surgical Aortopulmonary Shunt for Initial Palliation of Cyanotic Congenital Heart Disease with Ductal-Dependent Pulmonary Blood Flow: A Systematic Review and Meta-Analysis.
Tseng SY, Truong VT, Peck D, Kandi S, Brayer S, Jason DP 3rd, Mazur W, Hill GD, Ashfaq A, Goldstein BH, Alsaied T
J Am Heart Assoc 2022 Jul 5;11(13):e024721. Epub 2022 Jun 29 doi: 10.1161/JAHA.121.024721. PMID: 35766251Free PMC Article
Cardiovascular Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.
Alexander PMA, Checchia PA, Ryerson LM, Bohn D, Eckerle M, Gaies M, Laussen P, Jeffries H, Thiagarajan RR, Shekerdemian L, Bembea MM, Zimmerman JJ, Kissoon N; Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative
Pediatrics 2022 Jan 1;149(1 Suppl 1):S39-S47. doi: 10.1542/peds.2021-052888F. PMID: 34970677Free PMC Article
Animal Models of Repaired Tetralogy of Fallot: Current Applications and Future Perspectives.
Valdeomillos E, Jalal Z, Metras A, Roubertie F, Benoist D, Bernus O, Haïssaguerre M, Bordachar P, Iriart X, Thambo JB
Can J Cardiol 2019 Dec;35(12):1762-1771. Epub 2019 Jul 26 doi: 10.1016/j.cjca.2019.07.622. PMID: 31711822
Antibiotics for brain abscesses in people with cyanotic congenital heart disease.
Lumbiganon P, Chaikitpinyo A
Cochrane Database Syst Rev 2013 Mar 28;2013(3):CD004469. doi: 10.1002/14651858.CD004469.pub3. PMID: 23543532Free PMC Article
Antibiotics for brain abscesses in people with cyanotic congenital heart disease.
Lumbiganon P, Chaikitpinyo A
Cochrane Database Syst Rev 2007 Jul 18;(3):CD004469. doi: 10.1002/14651858.CD004469.pub2. PMID: 17636761

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