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Nonobstructive cardiomyopathy

MedGen UID:
538844
•Concept ID:
C0264787
•
Disease or Syndrome
SNOMED CT: Nonobstructive cardiomyopathy (69609002)

Professional guidelines

PubMed

Monitoring treatment with cardiac myosin inhibitors in symptomatic obstructive hypertrophic cardiomyopathy.
Chatur S, Hegde SM
Curr Opin Cardiol 2023 Sep 1;38(5):424-432. Epub 2023 Jun 26 doi: 10.1097/HCO.0000000000001068. PMID: 37382090
Morphologic criteria of progression and regression of cardiac hypertrophy.
Frenzel H, Schwartzkopff B, Rettig B, Vogelsang H
J Cardiovasc Pharmacol 1987;10 Suppl 6:S20-8. PMID: 2485027

Recent clinical studies

Etiology

Impediments to Heart Transplantation in Adults With MELAS(MT-TL1:m.3243A>G) Cardiomyopathy.
Di Toro A, Urtis M, Narula N, Giuliani L, Grasso M, Pasotti M, Pellegrini C, Serio A, Pilotto A, Antoniazzi E, Rampino T, Magrassi L, Valentini A, Cavallini A, Scelsi L, Ghio S, Abelli M, Olivotto I, Porcu M, Gavazzi A, Kodama T, Arbustini E
J Am Coll Cardiol 2022 Oct 11;80(15):1431-1443. doi: 10.1016/j.jacc.2022.04.067. PMID: 36202533
Mitochondrial long noncoding RNAs as blood based biomarkers for cardiac remodeling in patients with hypertrophic cardiomyopathy.
Kitow J, Derda AA, Beermann J, Kumarswarmy R, Pfanne A, Fendrich J, Lorenzen JM, Xiao K, Bavendiek U, Bauersachs J, Thum T
Am J Physiol Heart Circ Physiol 2016 Sep 1;311(3):H707-12. Epub 2016 Jul 15 doi: 10.1152/ajpheart.00194.2016. PMID: 27422984
Increased mean platelet volume in hypertrophic cardiomyopathy.
Icli A, Aksoy F, Dogan A, Arslan A, Akcay S, Yücel H, Ersoy I, Gorgulu O
Angiology 2014 May;65(5):420-4. Epub 2013 Apr 5 doi: 10.1177/0003319713483919. PMID: 23564022
Left ventricular regional relaxation and its nonuniformity in hypertrophic nonobstructive cardiomyopathy.
Hayashida W, Kumada T, Kohno F, Noda M, Ishikawa N, Kojima J, Himura Y, Kawai C
Circulation 1991 Oct;84(4):1496-504. doi: 10.1161/01.cir.84.4.1496. PMID: 1914092
The clinical course of primary myocardial disease in infants and children.
Greenwood RD, Nadas AS, Fyler DC
Am Heart J 1976 Nov;92(5):549-60. doi: 10.1016/s0002-8703(76)80074-9. PMID: 136183

Diagnosis

Impediments to Heart Transplantation in Adults With MELAS(MT-TL1:m.3243A>G) Cardiomyopathy.
Di Toro A, Urtis M, Narula N, Giuliani L, Grasso M, Pasotti M, Pellegrini C, Serio A, Pilotto A, Antoniazzi E, Rampino T, Magrassi L, Valentini A, Cavallini A, Scelsi L, Ghio S, Abelli M, Olivotto I, Porcu M, Gavazzi A, Kodama T, Arbustini E
J Am Coll Cardiol 2022 Oct 11;80(15):1431-1443. doi: 10.1016/j.jacc.2022.04.067. PMID: 36202533
Mitochondrial long noncoding RNAs as blood based biomarkers for cardiac remodeling in patients with hypertrophic cardiomyopathy.
Kitow J, Derda AA, Beermann J, Kumarswarmy R, Pfanne A, Fendrich J, Lorenzen JM, Xiao K, Bavendiek U, Bauersachs J, Thum T
Am J Physiol Heart Circ Physiol 2016 Sep 1;311(3):H707-12. Epub 2016 Jul 15 doi: 10.1152/ajpheart.00194.2016. PMID: 27422984
Increased mean platelet volume in hypertrophic cardiomyopathy.
Icli A, Aksoy F, Dogan A, Arslan A, Akcay S, Yücel H, Ersoy I, Gorgulu O
Angiology 2014 May;65(5):420-4. Epub 2013 Apr 5 doi: 10.1177/0003319713483919. PMID: 23564022
Hypertrophic obstructive and non-obstructive cardiomyopathy in Japan. Diagnosis of the disease with special reference to endomyocardial catheter biopsy.
Kawai C, Sakurai T, Fujiwara H, Matsumori A, Yui Y
Eur Heart J 1983 Nov;4 Suppl F:121-5. doi: 10.1093/eurheartj/4.suppl_f.121. PMID: 6686527
Hypertrophic nonobstructive cardiomyopathy: a precise assessment of hemodynamic characteristics and clinical implications.
Hirota Y, Furubayashi K, Kaku K, Shimizu G, Kino M, Kawamura K, Takatsu T
Am J Cardiol 1982 Nov;50(5):990-7. doi: 10.1016/0002-9149(82)90407-6. PMID: 6890306

Therapy

Monitoring treatment with cardiac myosin inhibitors in symptomatic obstructive hypertrophic cardiomyopathy.
Chatur S, Hegde SM
Curr Opin Cardiol 2023 Sep 1;38(5):424-432. Epub 2023 Jun 26 doi: 10.1097/HCO.0000000000001068. PMID: 37382090
Candesartan cilexetil: an update.
Joost A, Schunkert H, Radke PW
Expert Opin Pharmacother 2011 Aug;12(11):1769-80. Epub 2011 Jun 9 doi: 10.1517/14656566.2011.587000. PMID: 21651457
A new therapeutic strategy for hypertrophic nonobstructive cardiomyopathy in humans. A randomized and prospective study with an Angiotensin II receptor blocker.
Yamazaki T, Suzuki J, Shimamoto R, Tsuji T, Ohmoto-Sekine Y, Ohtomo K, Nagai R
Int Heart J 2007 Nov;48(6):715-24. doi: 10.1536/ihj.48.715. PMID: 18160763
Effect of intravenous administration of cibenzoline on left ventricular diastolic pressures in patients with hypertrophic cardiomyopathy: its relationship to transmitral Doppler flow profiles.
Hamada M, Aono J, Ikeda S, Watanabe K, Inaba S, Suzuki J, Ohtsuka T, Shigematsu Y
Circ J 2007 Oct;71(10):1540-4. doi: 10.1253/circj.71.1540. PMID: 17895548
Cibenzoline improves coronary flow velocity reserve in patients with hypertrophic obstructive cardiomyopathy.
Sekine T, Daimon M, Hasegawa R, Teramoto K, Kawata T, Tanaka N, Takei Y, Takazawa K, Yoshida K, Komuro I
Heart Vessels 2006 Nov;21(6):350-5. Epub 2006 Nov 27 doi: 10.1007/s00380-006-0917-1. PMID: 17143709

Prognosis

Increased mean platelet volume in hypertrophic cardiomyopathy.
Icli A, Aksoy F, Dogan A, Arslan A, Akcay S, Yücel H, Ersoy I, Gorgulu O
Angiology 2014 May;65(5):420-4. Epub 2013 Apr 5 doi: 10.1177/0003319713483919. PMID: 23564022
A new therapeutic strategy for hypertrophic nonobstructive cardiomyopathy in humans. A randomized and prospective study with an Angiotensin II receptor blocker.
Yamazaki T, Suzuki J, Shimamoto R, Tsuji T, Ohmoto-Sekine Y, Ohtomo K, Nagai R
Int Heart J 2007 Nov;48(6):715-24. doi: 10.1536/ihj.48.715. PMID: 18160763
Ventricular evoked response as clinical marker for hemodynamic changes in dilative cardiomyopathy.
Ebner E, Krätschmer H, Danilovic D, Hribernigg M, Hutten H
Pacing Clin Electrophysiol 2004 Feb;27(2):166-74. doi: 10.1111/j.1540-8159.2004.00406.x. PMID: 14764166
Increased intensity of the murmur of hypertrophic obstructive cardiomyopathy with carotid sinus pressure.
Klein HO, DiSegni E, Dean H, Beker B, Bakst A, Kaplinsky E
Chest 1988 Apr;93(4):814-20. doi: 10.1378/chest.93.4.814. PMID: 3349840
The clinical course of primary myocardial disease in infants and children.
Greenwood RD, Nadas AS, Fyler DC
Am Heart J 1976 Nov;92(5):549-60. doi: 10.1016/s0002-8703(76)80074-9. PMID: 136183

Clinical prediction guides

Increased mean platelet volume in hypertrophic cardiomyopathy.
Icli A, Aksoy F, Dogan A, Arslan A, Akcay S, Yücel H, Ersoy I, Gorgulu O
Angiology 2014 May;65(5):420-4. Epub 2013 Apr 5 doi: 10.1177/0003319713483919. PMID: 23564022
Hypertrophic obstructive and non-obstructive cardiomyopathy in Japan. Diagnosis of the disease with special reference to endomyocardial catheter biopsy.
Kawai C, Sakurai T, Fujiwara H, Matsumori A, Yui Y
Eur Heart J 1983 Nov;4 Suppl F:121-5. doi: 10.1093/eurheartj/4.suppl_f.121. PMID: 6686527
Hypertrophic nonobstructive cardiomyopathy: a precise assessment of hemodynamic characteristics and clinical implications.
Hirota Y, Furubayashi K, Kaku K, Shimizu G, Kino M, Kawamura K, Takatsu T
Am J Cardiol 1982 Nov;50(5):990-7. doi: 10.1016/0002-9149(82)90407-6. PMID: 6890306
The acute hemodynamic effects of ethacrynic acid and furosemide in patients with chronic postcapillary pulmonary hypertension.
Austin SM, Schreiner BF, Kramer DH, Shah PM, Yu PN
Circulation 1976 Feb;53(2):364-9. doi: 10.1161/01.cir.53.2.364. PMID: 1245044
The clinical course of primary myocardial disease in infants and children.
Greenwood RD, Nadas AS, Fyler DC
Am Heart J 1976 Nov;92(5):549-60. doi: 10.1016/s0002-8703(76)80074-9. PMID: 136183

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