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Hypertrophic condition of skin

MedGen UID:
538021
•Concept ID:
C0263630
•
Disease or Syndrome
Synonym: Hypertrophic skin
SNOMED CT: Hypertrophic skin (24782002); Hypertrophic condition of skin (24782002)

Professional guidelines

PubMed

A safety evaluation of ruxolitinib for the treatment of polycythemia vera.
Boldrini V, Vannucchi AM, Guglielmelli P
Expert Opin Drug Saf 2024 Jan;23(1):1-7. Epub 2023 Dec 29 doi: 10.1080/14740338.2023.2299391. PMID: 38156903
Isotretinoin and Timing of Procedural Interventions: A Systematic Review With Consensus Recommendations.
Spring LK, Krakowski AC, Alam M, Bhatia A, Brauer J, Cohen J, Del Rosso JQ, Diaz L, Dover J, Eichenfield LF, Gurtner GC, Hanke CW, Jahnke MN, Kelly KM, Khetarpal S, Kinney MA, Levy ML, Leyden J, Longaker MT, Munavalli GS, Ozog DM, Prather H, Shumaker PR, Tanzi E, Torres A, Velez MW, Waldman AB, Yan AC, Zaenglein AL
JAMA Dermatol 2017 Aug 1;153(8):802-809. doi: 10.1001/jamadermatol.2017.2077. PMID: 28658462
Keloids and Hypertrophic Scars: Pathophysiology, Classification, and Treatment.
Berman B, Maderal A, Raphael B
Dermatol Surg 2017 Jan;43 Suppl 1:S3-S18. doi: 10.1097/DSS.0000000000000819. PMID: 27347634

Recent clinical studies

Etiology

Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank.
Ung CY, Warwick A, Onoufriadis A, Barker JN, Parsons M, McGrath JA, Shaw TJ, Dand N
JAMA Dermatol 2023 Feb 1;159(2):172-181. doi: 10.1001/jamadermatol.2022.5607. PMID: 36598763Free PMC Article
Laser therapy for treating hypertrophic and keloid scars.
Leszczynski R, da Silva CA, Pinto ACPN, Kuczynski U, da Silva EM
Cochrane Database Syst Rev 2022 Sep 26;9(9):CD011642. doi: 10.1002/14651858.CD011642.pub2. PMID: 36161591Free PMC Article
Microneedling: Where do we stand now? A systematic review of the literature.
Ramaut L, Hoeksema H, Pirayesh A, Stillaert F, Monstrey S
J Plast Reconstr Aesthet Surg 2018 Jan;71(1):1-14. Epub 2017 Jun 17 doi: 10.1016/j.bjps.2017.06.006. PMID: 28690124
Isotretinoin and Timing of Procedural Interventions: A Systematic Review With Consensus Recommendations.
Spring LK, Krakowski AC, Alam M, Bhatia A, Brauer J, Cohen J, Del Rosso JQ, Diaz L, Dover J, Eichenfield LF, Gurtner GC, Hanke CW, Jahnke MN, Kelly KM, Khetarpal S, Kinney MA, Levy ML, Leyden J, Longaker MT, Munavalli GS, Ozog DM, Prather H, Shumaker PR, Tanzi E, Torres A, Velez MW, Waldman AB, Yan AC, Zaenglein AL
JAMA Dermatol 2017 Aug 1;153(8):802-809. doi: 10.1001/jamadermatol.2017.2077. PMID: 28658462
Interventions for acne scars.
Abdel Hay R, Shalaby K, Zaher H, Hafez V, Chi CC, Dimitri S, Nabhan AF, Layton AM
Cochrane Database Syst Rev 2016 Apr 3;4(4):CD011946. doi: 10.1002/14651858.CD011946.pub2. PMID: 27038134Free PMC Article

Diagnosis

Eosinophils in Traditionally Noneosinophil-Rich Dermatoses.
Sanchez I, Ibraheim MK, Lee BA, Kraus CN, Elsensohn A
Am J Dermatopathol 2023 Dec 1;45(12):820-821. doi: 10.1097/DAD.0000000000002550. PMID: 37883982
Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank.
Ung CY, Warwick A, Onoufriadis A, Barker JN, Parsons M, McGrath JA, Shaw TJ, Dand N
JAMA Dermatol 2023 Feb 1;159(2):172-181. doi: 10.1001/jamadermatol.2022.5607. PMID: 36598763Free PMC Article
Hypertrophic Osteoarthropathy: Clinical and Imaging Features.
Yap FY, Skalski MR, Patel DB, Schein AJ, White EA, Tomasian A, Masih S, Matcuk GR Jr
Radiographics 2017 Jan-Feb;37(1):157-195. Epub 2016 Dec 9 doi: 10.1148/rg.2017160052. PMID: 27935768
Leopard syndrome.
Sarkozy A, Digilio MC, Dallapiccola B
Orphanet J Rare Dis 2008 May 27;3:13. doi: 10.1186/1750-1172-3-13. PMID: 18505544Free PMC Article
The cardiofaciocutaneous syndrome.
Roberts A, Allanson J, Jadico SK, Kavamura MI, Noonan J, Opitz JM, Young T, Neri G
J Med Genet 2006 Nov;43(11):833-42. Epub 2006 Jul 6 doi: 10.1136/jmg.2006.042796. PMID: 16825433Free PMC Article

Therapy

A safety evaluation of ruxolitinib for the treatment of polycythemia vera.
Boldrini V, Vannucchi AM, Guglielmelli P
Expert Opin Drug Saf 2024 Jan;23(1):1-7. Epub 2023 Dec 29 doi: 10.1080/14740338.2023.2299391. PMID: 38156903
Laser therapy for treating hypertrophic and keloid scars.
Leszczynski R, da Silva CA, Pinto ACPN, Kuczynski U, da Silva EM
Cochrane Database Syst Rev 2022 Sep 26;9(9):CD011642. doi: 10.1002/14651858.CD011642.pub2. PMID: 36161591Free PMC Article
Microneedling: Where do we stand now? A systematic review of the literature.
Ramaut L, Hoeksema H, Pirayesh A, Stillaert F, Monstrey S
J Plast Reconstr Aesthet Surg 2018 Jan;71(1):1-14. Epub 2017 Jun 17 doi: 10.1016/j.bjps.2017.06.006. PMID: 28690124
Isotretinoin and Timing of Procedural Interventions: A Systematic Review With Consensus Recommendations.
Spring LK, Krakowski AC, Alam M, Bhatia A, Brauer J, Cohen J, Del Rosso JQ, Diaz L, Dover J, Eichenfield LF, Gurtner GC, Hanke CW, Jahnke MN, Kelly KM, Khetarpal S, Kinney MA, Levy ML, Leyden J, Longaker MT, Munavalli GS, Ozog DM, Prather H, Shumaker PR, Tanzi E, Torres A, Velez MW, Waldman AB, Yan AC, Zaenglein AL
JAMA Dermatol 2017 Aug 1;153(8):802-809. doi: 10.1001/jamadermatol.2017.2077. PMID: 28658462
Interventions for acne scars.
Abdel Hay R, Shalaby K, Zaher H, Hafez V, Chi CC, Dimitri S, Nabhan AF, Layton AM
Cochrane Database Syst Rev 2016 Apr 3;4(4):CD011946. doi: 10.1002/14651858.CD011946.pub2. PMID: 27038134Free PMC Article

Prognosis

Hypertrophic Osteoarthropathy: Clinical and Imaging Features.
Yap FY, Skalski MR, Patel DB, Schein AJ, White EA, Tomasian A, Masih S, Matcuk GR Jr
Radiographics 2017 Jan-Feb;37(1):157-195. Epub 2016 Dec 9 doi: 10.1148/rg.2017160052. PMID: 27935768
Laser surgery in rhinophyma.
Bassi A, Campolmi P, Dindelli M, Bruscino N, Conti R, Cannarozzo G, Pimpinelli N
G Ital Dermatol Venereol 2016 Feb;151(1):9-16. Epub 2014 Sep 18 PMID: 25236318
Myhre syndrome.
Le Goff C, Michot C, Cormier-Daire V
Clin Genet 2014 Jun;85(6):503-13. Epub 2014 Apr 2 doi: 10.1111/cge.12365. PMID: 24580733
Miscellaneous non-inflammatory musculoskeletal conditions. Pachydermoperiostosis.
Martinez-Lavin M
Best Pract Res Clin Rheumatol 2011 Oct;25(5):727-34. doi: 10.1016/j.berh.2011.10.019. PMID: 22142750
Leopard syndrome.
Sarkozy A, Digilio MC, Dallapiccola B
Orphanet J Rare Dis 2008 May 27;3:13. doi: 10.1186/1750-1172-3-13. PMID: 18505544Free PMC Article

Clinical prediction guides

Squamous Cell Carcinoma Arising in Chronic Inflammatory Dermatoses.
Kuraitis D, Murina A
Cutis 2024 Jan;113(1):29-34. doi: 10.12788/cutis.0914. PMID: 38478947
Association of Cutaneous Keloids, Hypertrophic Scarring, and Fibrosis with Risk of Postoperative Proliferative Vitreoretinopathy.
Mammo DA, Wai K, Rahimy E, Pan CK, Srivastava SK, Mruthyunjaya P
Ophthalmology 2024 Aug;131(8):961-966. Epub 2024 Feb 1 doi: 10.1016/j.ophtha.2024.01.032. PMID: 38296203
Scarring and Dyschromias in Fitzpatrick Skin Type IV-VI: A Review of Dermatologic Treatment Protocols.
Bourgeois J, Beer J, Jacob L, Henry M
J Drugs Dermatol 2023 Jul 1;22(7):7253. doi: 10.36849/JDD.7253. PMID: 37410031
Scarring and Dyschromias in Fitzpatrick Skin Type IV-VI: A Review of Dermatologic Treatment Protocols.
Bourgeois J, Beer J, Jacob L, Henry M
J Drugs Dermatol 2023 Mar 1;22(3):288-296. doi: 10.36849/JDD.7253. PMID: 36877886
Long-COVID and Post-COVID Health Complications: An Up-to-Date Review on Clinical Conditions and Their Possible Molecular Mechanisms.
Silva Andrade B, Siqueira S, de Assis Soares WR, de Souza Rangel F, Santos NO, Dos Santos Freitas A, Ribeiro da Silveira P, Tiwari S, Alzahrani KJ, Góes-Neto A, Azevedo V, Ghosh P, Barh D
Viruses 2021 Apr 18;13(4) doi: 10.3390/v13040700. PMID: 33919537Free PMC Article

Recent systematic reviews

Eosinophils in Traditionally Noneosinophil-Rich Dermatoses.
Sanchez I, Ibraheim MK, Lee BA, Kraus CN, Elsensohn A
Am J Dermatopathol 2023 Dec 1;45(12):820-821. doi: 10.1097/DAD.0000000000002550. PMID: 37883982
Laser therapy for treating hypertrophic and keloid scars.
Leszczynski R, da Silva CA, Pinto ACPN, Kuczynski U, da Silva EM
Cochrane Database Syst Rev 2022 Sep 26;9(9):CD011642. doi: 10.1002/14651858.CD011642.pub2. PMID: 36161591Free PMC Article
Microneedling: Where do we stand now? A systematic review of the literature.
Ramaut L, Hoeksema H, Pirayesh A, Stillaert F, Monstrey S
J Plast Reconstr Aesthet Surg 2018 Jan;71(1):1-14. Epub 2017 Jun 17 doi: 10.1016/j.bjps.2017.06.006. PMID: 28690124
Isotretinoin and Timing of Procedural Interventions: A Systematic Review With Consensus Recommendations.
Spring LK, Krakowski AC, Alam M, Bhatia A, Brauer J, Cohen J, Del Rosso JQ, Diaz L, Dover J, Eichenfield LF, Gurtner GC, Hanke CW, Jahnke MN, Kelly KM, Khetarpal S, Kinney MA, Levy ML, Leyden J, Longaker MT, Munavalli GS, Ozog DM, Prather H, Shumaker PR, Tanzi E, Torres A, Velez MW, Waldman AB, Yan AC, Zaenglein AL
JAMA Dermatol 2017 Aug 1;153(8):802-809. doi: 10.1001/jamadermatol.2017.2077. PMID: 28658462
Interventions for acne scars.
Abdel Hay R, Shalaby K, Zaher H, Hafez V, Chi CC, Dimitri S, Nabhan AF, Layton AM
Cochrane Database Syst Rev 2016 Apr 3;4(4):CD011946. doi: 10.1002/14651858.CD011946.pub2. PMID: 27038134Free PMC Article

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