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Gianotti-Crosti syndrome

MedGen UID:
120475
•Concept ID:
C0263372
•
Disease or Syndrome
Synonyms: Acrodermatitis Papulosa Infantum; Acrodermatitis Papulosa Infantums; Acropapulo Vesicular Syndrome; Acropapulo-Vesicular Syndrome; Acropapulo-Vesicular Syndromes; Childhood Papular Acrodermatitides; Childhood Papular Acrodermatitis; Erythemato Vesiculo Papulous Eruptive Syndrome; Erythemato-Vesiculo-Papulous Eruptive Syndrome; Erythemato-Vesiculo-Papulous Eruptive Syndromes; Gianotti Crosti Syndrome; Gianotti-Crosti Syndrome; Infantile Papular Acrodermatitides; Infantile Papular Acrodermatitis; Papular Acrodermatitides, Infantile; Papular Acrodermatitis of Childhood; Papular Acrodermatitis, Infantile; Papulovesicular Acrolocated Syndrome; Papulovesicular Acrolocated Syndromes; Syndrome, Acropapulo-Vesicular; Syndrome, Erythemato-Vesiculo-Papulous Eruptive; Syndrome, Gianotti-Crosti; Syndromes, Acropapulo-Vesicular; Syndromes, Erythemato-Vesiculo-Papulous Eruptive; Syndromes, Papulovesicular Acrolocated
SNOMED CT: Gianotti-Crosti syndrome (82721003); Acrodermatitis papulosa infantum (82721003); Infantile papular acrodermatitis (82721003); Papular acrodermatitis of childhood (82721003); Acrodermatitis (82721003)

Professional guidelines

PubMed

Gianotti-Crosti syndrome-like reaction to molluscum contagiosum-Clinical characteristics and response to treatment.
Bürgler C, Weibel L, Schwieger-Briel A, Knöpfel N, Luchsinger I, Theiler M
J Dtsch Dermatol Ges 2021 Dec;19(12):1746-1751. Epub 2021 Nov 10 doi: 10.1111/ddg.14608. PMID: 34761533Free PMC Article
The diagnostic criteria of Gianotti-Crosti syndrome: are they applicable to children in India?
Chuh A, Lee A, Zawar V
Pediatr Dermatol 2004 Sep-Oct;21(5):542-7. doi: 10.1111/j.0736-8046.2004.21503.x. PMID: 15461758
Diagnostic criteria for Gianotti-Crosti syndrome: a prospective case-control study for validity assessment.
Chuh AA
Cutis 2001 Sep;68(3):207-13. PMID: 11579787

Recent clinical studies

Etiology

Gianotti-Crosti syndrome-like reaction to molluscum contagiosum-Clinical characteristics and response to treatment.
Bürgler C, Weibel L, Schwieger-Briel A, Knöpfel N, Luchsinger I, Theiler M
J Dtsch Dermatol Ges 2021 Dec;19(12):1746-1751. Epub 2021 Nov 10 doi: 10.1111/ddg.14608. PMID: 34761533Free PMC Article
Risk of scarring in Gianotti-Crosti Syndrome.
Chiriac A, Podoleanu C, Stolnicu S
Minerva Pediatr (Torino) 2021 Aug;73(4):377-378. Epub 2020 Aug 4 doi: 10.23736/S2724-5276.20.05965-4. PMID: 32748609
Cutaneous manifestations of HAV, HBV, HCV.
Cozzani E, Herzum A, Burlando M, Parodi A
Ital J Dermatol Venerol 2021 Feb;156(1):5-12. Epub 2019 Dec 4 doi: 10.23736/S2784-8671.19.06488-5. PMID: 31804053
Paraviral exanthems.
Fölster-Holst R, Zawar VP, Chuh A
Expert Rev Anti Infect Ther 2016 Jun;14(6):601-11. doi: 10.1080/14787210.2016.1184084. PMID: 27144956
Gianotti-Crosti syndrome following childhood vaccinations.
Retrouvey M, Koch LH, Williams JV
Pediatr Dermatol 2013 Jan-Feb;30(1):137-8. Epub 2011 Dec 6 doi: 10.1111/j.1525-1470.2011.01636.x. PMID: 22141410

Diagnosis

Gianotti-Crosti Syndrome after SARS-CoV-2 infection.
Gori N, Quattrini L, Chiricozzi A, Sfregola S, Federico F, Peris K
Ital J Dermatol Venerol 2022 Oct;157(5):460-462. doi: 10.23736/S2784-8671.22.07250-4. PMID: 36213977
Gianotti-Crosti syndrome-like eruption and molluscum contagiosum.
Bennardo L, Napolitano M, Tolone M, Nisticò SP, Dastoli S, Passante M, Patruno C
Ital J Dermatol Venerol 2022 Apr;157(2):197-198. Epub 2021 May 28 doi: 10.23736/S2784-8671.21.06983-8. PMID: 34044509
Gianotti-Crosti syndrome (papular acrodermatitis of childhood) in the era of a viral recrudescence and vaccine opposition.
Leung AKC, Sergi CM, Lam JM, Leong KF
World J Pediatr 2019 Dec;15(6):521-527. Epub 2019 May 27 doi: 10.1007/s12519-019-00269-9. PMID: 31134587
Paraviral exanthems.
Fölster-Holst R, Zawar VP, Chuh A
Expert Rev Anti Infect Ther 2016 Jun;14(6):601-11. doi: 10.1080/14787210.2016.1184084. PMID: 27144956
Viral Skin Diseases.
Ramdass P, Mullick S, Farber HF
Prim Care 2015 Dec;42(4):517-67. doi: 10.1016/j.pop.2015.08.006. PMID: 26612372

Therapy

Gianotti-Crosti syndrome (papular acrodermatitis of childhood) in the era of a viral recrudescence and vaccine opposition.
Leung AKC, Sergi CM, Lam JM, Leong KF
World J Pediatr 2019 Dec;15(6):521-527. Epub 2019 May 27 doi: 10.1007/s12519-019-00269-9. PMID: 31134587
Paraviral exanthems.
Fölster-Holst R, Zawar VP, Chuh A
Expert Rev Anti Infect Ther 2016 Jun;14(6):601-11. doi: 10.1080/14787210.2016.1184084. PMID: 27144956
Viral Skin Diseases.
Ramdass P, Mullick S, Farber HF
Prim Care 2015 Dec;42(4):517-67. doi: 10.1016/j.pop.2015.08.006. PMID: 26612372
Gianotti-Crosti syndrome following childhood vaccinations.
Retrouvey M, Koch LH, Williams JV
Pediatr Dermatol 2013 Jan-Feb;30(1):137-8. Epub 2011 Dec 6 doi: 10.1111/j.1525-1470.2011.01636.x. PMID: 22141410
Lichenoid eruptions in children.
Tilly JJ, Drolet BA, Esterly NB
J Am Acad Dermatol 2004 Oct;51(4):606-24. doi: 10.1016/j.jaad.2003.12.012. PMID: 15389198

Prognosis

Gianotti-Crosti syndrome-like reaction to molluscum contagiosum-Clinical characteristics and response to treatment.
Bürgler C, Weibel L, Schwieger-Briel A, Knöpfel N, Luchsinger I, Theiler M
J Dtsch Dermatol Ges 2021 Dec;19(12):1746-1751. Epub 2021 Nov 10 doi: 10.1111/ddg.14608. PMID: 34761533Free PMC Article
Paraviral exanthems.
Fölster-Holst R, Zawar VP, Chuh A
Expert Rev Anti Infect Ther 2016 Jun;14(6):601-11. doi: 10.1080/14787210.2016.1184084. PMID: 27144956
Gianotti-Crosti syndrome following childhood vaccinations.
Retrouvey M, Koch LH, Williams JV
Pediatr Dermatol 2013 Jan-Feb;30(1):137-8. Epub 2011 Dec 6 doi: 10.1111/j.1525-1470.2011.01636.x. PMID: 22141410
Gianotti-Crosti syndrome.
Brandt O, Abeck D, Gianotti R, Burgdorf W
J Am Acad Dermatol 2006 Jan;54(1):136-45. Epub 2005 Dec 2 doi: 10.1016/j.jaad.2005.09.033. PMID: 16384769
Lichenoid eruptions in children.
Tilly JJ, Drolet BA, Esterly NB
J Am Acad Dermatol 2004 Oct;51(4):606-24. doi: 10.1016/j.jaad.2003.12.012. PMID: 15389198

Clinical prediction guides

Gianotti-Crosti syndrome (papular acrodermatitis of childhood) in the era of a viral recrudescence and vaccine opposition.
Leung AKC, Sergi CM, Lam JM, Leong KF
World J Pediatr 2019 Dec;15(6):521-527. Epub 2019 May 27 doi: 10.1007/s12519-019-00269-9. PMID: 31134587
Unusual Eruptions Associated with Mycoplasma pneumoniae Respiratory Infections: Review of the Literature.
Terraneo L, Lava SA, Camozzi P, Zgraggen L, Simonetti GD, Bianchetti MG, Milani GP
Dermatology 2015;231(2):152-7. Epub 2015 Jun 6 doi: 10.1159/000430809. PMID: 26067570
Epstein-Barr virus and skin manifestations in childhood.
Di Lernia V, Mansouri Y
Int J Dermatol 2013 Oct;52(10):1177-84. doi: 10.1111/j.1365-4632.2012.05855.x. PMID: 24073903
The diagnostic criteria of Gianotti-Crosti syndrome: are they applicable to children in India?
Chuh A, Lee A, Zawar V
Pediatr Dermatol 2004 Sep-Oct;21(5):542-7. doi: 10.1111/j.0736-8046.2004.21503.x. PMID: 15461758
Lichenoid eruptions in children.
Tilly JJ, Drolet BA, Esterly NB
J Am Acad Dermatol 2004 Oct;51(4):606-24. doi: 10.1016/j.jaad.2003.12.012. PMID: 15389198

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