U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Incomplete right bundle branch block

MedGen UID:
82648
Concept ID:
C0262525
Disease or Syndrome
SNOMED CT: Incomplete right bundle branch block (251124007)
 
HPO: HP:6000313

Definition

Right bundle branch block (RBBB) represents an abnormality in the intraventricular electrical conduction system of the human heart, generating enlarged QRS and modified vectors on the electrocardiogram (ECG). Incomplete RBBB (IRBBB) is defined by (i) QRS duration between 110 and 120 ms in adults; (ii) rsr, rsR, or rSR in leads V1 or V2. The R or r deflection is usually wider than the initial R wave. In a minority of patients, a wide and often notched R wave pattern may be seen in leads V1 and/or V2; (iii) S wave of greater duration than R wave or greater than 40 ms in leads I and V6 in adults; and (iv) Normal R peak time in leads V5 and V6 but greater than 50 ms in lead V1. The first 3 criteria should be present to make the diagnosis. When a pure dominant R wave with or without a notch is present in V1, criterion 4 should be satisfied. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncomplete right bundle branch block

Conditions with this feature

Dilated cardiomyopathy 1D
MedGen UID:
316943
Concept ID:
C1832243
Disease or Syndrome
Left ventricular noncompaction is a heart (cardiac) muscle disorder that occurs when the lower left chamber of the heart (left ventricle), which helps the heart pump blood, does not develop correctly. Instead of the muscle being smooth and firm, the cardiac muscle in the left ventricle is thick and appears spongy. The abnormal cardiac muscle is weak and has an impaired ability to pump blood because it either cannot completely contract or it cannot completely relax. For the heart to pump blood normally, cardiac muscle must contract and relax fully.\n\nSome individuals with left ventricular noncompaction experience no symptoms at all; others have heart problems that can include sudden cardiac death. Additional signs and symptoms include abnormal blood clots, irregular heart rhythm (arrhythmia), a sensation of fluttering or pounding in the chest (palpitations), extreme fatigue during exercise (exercise intolerance), shortness of breath (dyspnea), fainting (syncope), swelling of the legs (lymphedema), and trouble laying down flat. Some affected individuals have features of other heart defects. Left ventricular noncompaction can be diagnosed at any age, from birth to late adulthood. Approximately two-thirds of individuals with left ventricular noncompaction develop heart failure.

Professional guidelines

PubMed

Chevallier S, Forclaz A, Tenkorang J, Ahmad Y, Faouzi M, Graf D, Schlaepfer J, Pruvot E
J Am Coll Cardiol 2011 Nov 22;58(22):2290-8. doi: 10.1016/j.jacc.2011.08.039. PMID: 22093505
Ohkubo K, Watanabe I, Okumura Y, Ashino S, Kofune M, Nagashima K, Nakai T, Kunimoto S, Kasamaki Y, Hirayama A
Int Heart J 2011;52(3):159-63. doi: 10.1536/ihj.52.159. PMID: 21646738
Muta H, Akagi T, Egami K, Furui J, Sugahara Y, Ishii M, Matsuishi T
Circ J 2003 Feb;67(2):112-5. doi: 10.1253/circj.67.112. PMID: 12547990

Recent clinical studies

Etiology

Abela M, Sharma S
Minerva Cardiol Angiol 2021 Oct;69(5):533-556. Epub 2020 Oct 15 doi: 10.23736/S2724-5683.20.05331-1. PMID: 33059398
Alventosa-Zaidin M, Pera G, Roca Saumell C, Mengual Miralles N, Zamora Sanchez MV, Gros Garcia T, Guix Font L, Benitez Camps M, Francisco-Pascual J, Brugada Terradellas J
BMC Fam Pract 2019 May 6;20(1):58. doi: 10.1186/s12875-019-0946-3. PMID: 31060516Free PMC Article
Labombarda F, Maurice M, Simon JP, Legallois D, Guyant-Maréchal L, Bedat-Millet AL, Merle P, Saloux E, Chapon F, Milliez P
J Clin Neuromuscul Dis 2017 Jun;18(4):199-206. doi: 10.1097/CND.0000000000000144. PMID: 28538250
Kapoor-Katari K, Neustein SM
Middle East J Anaesthesiol 2012 Jun;21(5):743-6. PMID: 23265041
Calcaterra G, Puglisi R
Int J Cardiol 1989 Aug;24(2):236-8. doi: 10.1016/0167-5273(89)90312-4. PMID: 2767802

Diagnosis

Umer M, Sagheer U, Furtado W, Shotwell M, Joshi J, Shetty M, Kalra DK
Radiology 2024 Jul;312(1):e232440. doi: 10.1148/radiol.232440. PMID: 39078295
Tsuchihashi T, Kamada M, Nakano Y
Cardiol Young 2022 Aug;32(8):1344-1346. Epub 2021 Dec 20 doi: 10.1017/S1047951121005023. PMID: 34924076
Labombarda F, Maurice M, Simon JP, Legallois D, Guyant-Maréchal L, Bedat-Millet AL, Merle P, Saloux E, Chapon F, Milliez P
J Clin Neuromuscul Dis 2017 Jun;18(4):199-206. doi: 10.1097/CND.0000000000000144. PMID: 28538250
Francis J, Antzelevitch C
Int J Cardiol 2005 May 25;101(2):173-8. doi: 10.1016/j.ijcard.2004.03.068. PMID: 15882659Free PMC Article
Butrous GS, Dowd PM, Milne J, Dymond DS, Caplin J, Camm AJ
Postgrad Med J 1985 Aug;61(718):679-84. doi: 10.1136/pgmj.61.718.679. PMID: 4034457Free PMC Article

Therapy

Minato H, Yoshikawa A, Tsuyama S, Katayanagi K, Hachiya S, Ohta K, Myojo Y
Medicine (Baltimore) 2024 Feb 2;103(5):e37196. doi: 10.1097/MD.0000000000037196. PMID: 38306524Free PMC Article
Franco E, Dias A, Teresa D, Hebert K
Ann Noninvasive Electrocardiol 2014 Mar;19(2):198-202. Epub 2013 Sep 9 doi: 10.1111/anec.12086. PMID: 24620847Free PMC Article
Sarkozy A, Caenepeel A, Geelen P, Peytchev P, de Zutter M, Brugada P
Europace 2005 Nov;7(6):537-9. doi: 10.1016/j.eupc.2005.06.013. PMID: 16216754
Phillips N, Priestley M, Denniss AR, Uther JB
Anesth Analg 2003 Jul;97(1):264-7, table of contents. doi: 10.1213/01.ane.0000067410.32384.3a. PMID: 12818979
Hollister LE
J Clin Psychiatry 1995 Jan;56(1):26-9. PMID: 7836336

Prognosis

Ruiz-Guevara R, Alarcón de Noya B, Mendoza I, Rojas C, Machado I, Díaz-Bello Z, Muñoz-Calderón A, Castro J, Noya O
PLoS Negl Trop Dis 2023 Oct;17(10):e0011643. Epub 2023 Oct 6 doi: 10.1371/journal.pntd.0011643. PMID: 37801449Free PMC Article
Meziab O, Abrams DJ, Alexander ME, Bevilacqua L, Bezzerides V, Mah DY, Walsh EP, Triedman JK
Congenit Heart Dis 2018 May;13(3):419-427. Epub 2018 Feb 12 doi: 10.1111/chd.12589. PMID: 29431296
van Dijk GP, van der Kooi E, Behin A, Smeets J, Timmermans J, van der Maarel S, Padberg G, Voermans N, van Engelen B
Funct Neurol 2014 Jul-Sep;29(3):159-65. PMID: 25473735Free PMC Article
Calcaterra G, Puglisi R
Int J Cardiol 1989 Aug;24(2):236-8. doi: 10.1016/0167-5273(89)90312-4. PMID: 2767802
Liao YL, Emidy LA, Dyer A, Hewitt JS, Shekelle RB, Paul O, Prineas R, Stamler J
J Am Coll Cardiol 1986 Mar;7(3):492-9. doi: 10.1016/s0735-1097(86)80458-2. PMID: 3950228

Clinical prediction guides

Ruiz-Guevara R, Alarcón de Noya B, Mendoza I, Rojas C, Machado I, Díaz-Bello Z, Muñoz-Calderón A, Castro J, Noya O
PLoS Negl Trop Dis 2023 Oct;17(10):e0011643. Epub 2023 Oct 6 doi: 10.1371/journal.pntd.0011643. PMID: 37801449Free PMC Article
Abela M, Sharma S
Minerva Cardiol Angiol 2021 Oct;69(5):533-556. Epub 2020 Oct 15 doi: 10.23736/S2724-5683.20.05331-1. PMID: 33059398
Diaz-Gonzalez L, Bruña V, Velásquez-Rodriguez J, Valenzuela PL, Valero-Masa MJ, González-Saldívar H, Martinez-Sellés M, Lucia A, Boraita A
Scand J Med Sci Sports 2020 Oct;30(10):1992-1998. Epub 2020 Jul 24 doi: 10.1111/sms.13763. PMID: 32640481
Alventosa-Zaidin M, Pera G, Roca Saumell C, Mengual Miralles N, Zamora Sanchez MV, Gros Garcia T, Guix Font L, Benitez Camps M, Francisco-Pascual J, Brugada Terradellas J
BMC Fam Pract 2019 May 6;20(1):58. doi: 10.1186/s12875-019-0946-3. PMID: 31060516Free PMC Article
Butrous GS, Dowd PM, Milne J, Dymond DS, Caplin J, Camm AJ
Postgrad Med J 1985 Aug;61(718):679-84. doi: 10.1136/pgmj.61.718.679. PMID: 4034457Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...