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Filoviridae infectious disease

MedGen UID:
67006
Concept ID:
C0242917
Disease or Syndrome
Synonyms: Filoviridae Infection; Filoviridae Infections; Filovirus Infection; Filovirus Infections; Infection, Filoviridae; Infection, Filovirus; Infections, Filoviridae
SNOMED CT: Disease caused by Filoviridae (198007)
 
Monarch Initiative: MONDO:0005762

Definition

Infections with viruses of the family filoviridae. The infections in humans consist of a variety of clinically similar viral hemorrhagic fevers but the natural reservoir host is unknown. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFiloviridae infectious disease

Professional guidelines

PubMed

Nicastri E, Kobinger G, Vairo F, Montaldo C, Mboera LEG, Ansunama R, Zumla A, Ippolito G
Infect Dis Clin North Am 2019 Dec;33(4):953-976. doi: 10.1016/j.idc.2019.08.005. PMID: 31668200
Keshtkar-Jahromi M, Martins KAO, Cardile AP, Reisler RB, Christopher GW, Bavari S
Expert Rev Anti Infect Ther 2018 Jan;16(1):67-76. Epub 2017 Dec 20 doi: 10.1080/14787210.2018.1413937. PMID: 29210303
Bociaga-Jasik M, Piatek A, Garlicki A
Folia Med Cracov 2014;54(3):49-55. PMID: 25694095

Recent clinical studies

Etiology

PREVAC Study Team, Kieh M, Richert L, Beavogui AH, Grund B, Leigh B, D'Ortenzio E, Doumbia S, Lhomme E, Sow S, Vatrinet R, Roy C, Kennedy SB, Faye S, Lees S, Millimouno NP, Camara AM, Samai M, Deen GF, Doumbia M, Espérou H, Pierson J, Watson-Jones D, Diallo A, Wentworth D, McLean C, Simon J, Wiedemann A, Dighero-Kemp B, Hensley L, Lane HC, Levy Y, Piot P, Greenwood B, Chêne G, Neaton J, Yazdanpanah Y
N Engl J Med 2022 Dec 29;387(26):2411-2424. Epub 2022 Dec 14 doi: 10.1056/NEJMoa2200072. PMID: 36516078
Bugert JJ, Hucke F, Zanetta P, Bassetto M, Brancale A
Virus Genes 2020 Apr;56(2):150-167. Epub 2020 Feb 19 doi: 10.1007/s11262-020-01737-5. PMID: 32076918Free PMC Article
Mulangu S, Dodd LE, Davey RT Jr, Tshiani Mbaya O, Proschan M, Mukadi D, Lusakibanza Manzo M, Nzolo D, Tshomba Oloma A, Ibanda A, Ali R, Coulibaly S, Levine AC, Grais R, Diaz J, Lane HC, Muyembe-Tamfum JJ; PALM Writing Group, Sivahera B, Camara M, Kojan R, Walker R, Dighero-Kemp B, Cao H, Mukumbayi P, Mbala-Kingebeni P, Ahuka S, Albert S, Bonnett T, Crozier I, Duvenhage M, Proffitt C, Teitelbaum M, Moench T, Aboulhab J, Barrett K, Cahill K, Cone K, Eckes R, Hensley L, Herpin B, Higgs E, Ledgerwood J, Pierson J, Smolskis M, Sow Y, Tierney J, Sivapalasingam S, Holman W, Gettinger N, Vallée D, Nordwall J; PALM Consortium Study Team
N Engl J Med 2019 Dec 12;381(24):2293-2303. Epub 2019 Nov 27 doi: 10.1056/NEJMoa1910993. PMID: 31774950Free PMC Article
Cardile AP, Warren TK, Martins KA, Reisler RB, Bavari S
Annu Rev Pharmacol Toxicol 2017 Jan 6;57:329-348. Epub 2016 Dec 7 doi: 10.1146/annurev-pharmtox-010716-105055. PMID: 27959624
Stein RA
Int J Clin Pract 2015 Jan;69(1):49-58. Epub 2014 Dec 11 doi: 10.1111/ijcp.12593. PMID: 25496121Free PMC Article

Diagnosis

Feldmann H, Sprecher A, Geisbert TW
N Engl J Med 2020 May 7;382(19):1832-1842. doi: 10.1056/NEJMra1901594. PMID: 32441897
Jacob ST, Crozier I, Fischer WA 2nd, Hewlett A, Kraft CS, Vega MA, Soka MJ, Wahl V, Griffiths A, Bollinger L, Kuhn JH
Nat Rev Dis Primers 2020 Feb 20;6(1):13. doi: 10.1038/s41572-020-0147-3. PMID: 32080199Free PMC Article
Nicastri E, Kobinger G, Vairo F, Montaldo C, Mboera LEG, Ansunama R, Zumla A, Ippolito G
Infect Dis Clin North Am 2019 Dec;33(4):953-976. doi: 10.1016/j.idc.2019.08.005. PMID: 31668200
Richardson KJ
Adv Emerg Nurs J 2015 Apr-Jun;37(2):102-15. doi: 10.1097/TME.0000000000000063. PMID: 25929221
Stein RA
Int J Clin Pract 2015 Jan;69(1):49-58. Epub 2014 Dec 11 doi: 10.1111/ijcp.12593. PMID: 25496121Free PMC Article

Therapy

Feldmann H, Sprecher A, Geisbert TW
N Engl J Med 2020 May 7;382(19):1832-1842. doi: 10.1056/NEJMra1901594. PMID: 32441897
Jacob ST, Crozier I, Fischer WA 2nd, Hewlett A, Kraft CS, Vega MA, Soka MJ, Wahl V, Griffiths A, Bollinger L, Kuhn JH
Nat Rev Dis Primers 2020 Feb 20;6(1):13. doi: 10.1038/s41572-020-0147-3. PMID: 32080199Free PMC Article
Mulangu S, Dodd LE, Davey RT Jr, Tshiani Mbaya O, Proschan M, Mukadi D, Lusakibanza Manzo M, Nzolo D, Tshomba Oloma A, Ibanda A, Ali R, Coulibaly S, Levine AC, Grais R, Diaz J, Lane HC, Muyembe-Tamfum JJ; PALM Writing Group, Sivahera B, Camara M, Kojan R, Walker R, Dighero-Kemp B, Cao H, Mukumbayi P, Mbala-Kingebeni P, Ahuka S, Albert S, Bonnett T, Crozier I, Duvenhage M, Proffitt C, Teitelbaum M, Moench T, Aboulhab J, Barrett K, Cahill K, Cone K, Eckes R, Hensley L, Herpin B, Higgs E, Ledgerwood J, Pierson J, Smolskis M, Sow Y, Tierney J, Sivapalasingam S, Holman W, Gettinger N, Vallée D, Nordwall J; PALM Consortium Study Team
N Engl J Med 2019 Dec 12;381(24):2293-2303. Epub 2019 Nov 27 doi: 10.1056/NEJMoa1910993. PMID: 31774950Free PMC Article
Furuyama W, Marzi A
Annu Rev Virol 2019 Sep 29;6(1):435-458. doi: 10.1146/annurev-virology-092818-015708. PMID: 31567063
Bradfute SB, Dye JM Jr, Bavari S
Hum Vaccin 2011 Jun;7(6):701-11. Epub 2011 Jun 1 doi: 10.4161/hv.7.6.15398. PMID: 21519188Free PMC Article

Prognosis

Escudero-Pérez B, Lawrence P, Castillo-Olivares J
Front Immunol 2023;14:1156758. Epub 2023 Apr 17 doi: 10.3389/fimmu.2023.1156758. PMID: 37153606Free PMC Article
Mirza MU, Vanmeert M, Ali A, Iman K, Froeyen M, Idrees M
J Med Virol 2019 Dec;91(12):2029-2048. Epub 2019 Sep 30 doi: 10.1002/jmv.25357. PMID: 30431654Free PMC Article
Baseler L, Chertow DS, Johnson KM, Feldmann H, Morens DM
Annu Rev Pathol 2017 Jan 24;12:387-418. doi: 10.1146/annurev-pathol-052016-100506. PMID: 27959626
Cnops L, van Griensven J, Honko AN, Bausch DG, Sprecher A, Hill CE, Colebunders R, Johnson JC, Griffiths A, Palacios GF, Kraft CS, Kobinger G, Hewlett A, Norwood DA, Sabeti P, Jahrling PB, Formenty P, Kuhn JH, Ariën KK
Lancet Infect Dis 2016 Jul;16(7):e134-e138. Epub 2016 Jun 10 doi: 10.1016/S1473-3099(16)30063-9. PMID: 27296694
Martines RB, Ng DL, Greer PW, Rollin PE, Zaki SR
J Pathol 2015 Jan;235(2):153-74. doi: 10.1002/path.4456. PMID: 25297522

Clinical prediction guides

Tang H, Abouleila Y, Saris A, Shimizu Y, Ottenhoff THM, Mashaghi A
J Mol Med (Berl) 2023 May;101(5):557-568. Epub 2023 Mar 24 doi: 10.1007/s00109-023-02309-4. PMID: 36959259Free PMC Article
Jacob ST, Crozier I, Fischer WA 2nd, Hewlett A, Kraft CS, Vega MA, Soka MJ, Wahl V, Griffiths A, Bollinger L, Kuhn JH
Nat Rev Dis Primers 2020 Feb 20;6(1):13. doi: 10.1038/s41572-020-0147-3. PMID: 32080199Free PMC Article
Reynolds P, Marzi A
Virus Genes 2017 Aug;53(4):501-515. Epub 2017 Apr 26 doi: 10.1007/s11262-017-1455-x. PMID: 28447193Free PMC Article
Baseler L, Chertow DS, Johnson KM, Feldmann H, Morens DM
Annu Rev Pathol 2017 Jan 24;12:387-418. doi: 10.1146/annurev-pathol-052016-100506. PMID: 27959626
Ascenzi P, Bocedi A, Heptonstall J, Capobianchi MR, Di Caro A, Mastrangelo E, Bolognesi M, Ippolito G
Mol Aspects Med 2008 Jun;29(3):151-85. Epub 2007 Oct 22 doi: 10.1016/j.mam.2007.09.005. PMID: 18063023

Recent systematic reviews

Muzembo BA, Kitahara K, Mitra D, Ntontolo NP, Ngatu NR, Ohno A, Khatiwada J, Dutta S, Miyoshi SI
Travel Med Infect Dis 2024 Jan-Feb;57:102685. Epub 2024 Jan 3 doi: 10.1016/j.tmaid.2023.102685. PMID: 38181864
Cuomo-Dannenburg G, McCain K, McCabe R, Unwin HJT, Doohan P, Nash RK, Hicks JT, Charniga K, Geismar C, Lambert B, Nikitin D, Skarp J, Wardle J, Kont M, Bhatia S, Imai N, van Elsland S, Cori A, Morgenstern C; Pathogen Epidemiology Review Group
Lancet Infect Dis 2024 May;24(5):e307-e317. Epub 2023 Nov 28 doi: 10.1016/S1473-3099(23)00515-7. PMID: 38040006Free PMC Article
Bower H, Glynn JR
Sci Data 2017 Jan 31;4:160133. doi: 10.1038/sdata.2016.133. PMID: 28140390Free PMC Article
Brainard J, Pond K, Hooper L, Edmunds K, Hunter P
PLoS Negl Trop Dis 2016 Feb;10(2):e0004475. Epub 2016 Feb 29 doi: 10.1371/journal.pntd.0004475. PMID: 26927697Free PMC Article
Velásquez GE, Aibana O, Ling EJ, Diakite I, Mooring EQ, Murray MB
Clin Infect Dis 2015 Oct 1;61(7):1135-40. Epub 2015 Jun 30 doi: 10.1093/cid/civ531. PMID: 26129757Free PMC Article

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