U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Neoplasm of male breast

MedGen UID:
66983
•Concept ID:
C0242788
•
Neoplastic Process
Synonyms: Breast Neoplasm, Male; Breast Neoplasms, Male; Breast Tumor, Male; Breast Tumors, Male; Male Breast Neoplasm; Male Breast Neoplasms; Male Breast Tumor; Male Breast Tumors; Neoplasm, Male Breast; Neoplasms, Breast, Male; Neoplasms, Male Breast; Tumor, Male Breast; Tumors, Breast, Male; Tumors, Male Breast
SNOMED CT: Neoplasm of male breast (126937006)

Definition

Any neoplasms of the male breast. These occur infrequently in males in developed countries, the incidence being about 1% of that in females. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNeoplasm of male breast

Professional guidelines

PubMed

EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent.
Mottet N, van den Bergh RCN, Briers E, Van den Broeck T, Cumberbatch MG, De Santis M, Fanti S, Fossati N, Gandaglia G, Gillessen S, Grivas N, Grummet J, Henry AM, van der Kwast TH, Lam TB, Lardas M, Liew M, Mason MD, Moris L, Oprea-Lager DE, van der Poel HG, Rouvière O, Schoots IG, Tilki D, Wiegel T, Willemse PM, Cornford P
Eur Urol 2021 Feb;79(2):243-262. Epub 2020 Nov 7 doi: 10.1016/j.eururo.2020.09.042. PMID: 33172724
Lymphoma: Diagnosis and Treatment.
Lewis WD, Lilly S, Jones KL
Am Fam Physician 2020 Jan 1;101(1):34-41. PMID: 31894937
Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†.
Cardoso F, Kyriakides S, Ohno S, Penault-Llorca F, Poortmans P, Rubio IT, Zackrisson S, Senkus E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2019 Aug 1;30(8):1194-1220. doi: 10.1093/annonc/mdz173. PMID: 31161190

Recent clinical studies

Etiology

Male breast cancer: a disease distinct from female breast cancer.
Gucalp A, Traina TA, Eisner JR, Parker JS, Selitsky SR, Park BH, Elias AD, Baskin-Bey ES, Cardoso F
Breast Cancer Res Treat 2019 Jan;173(1):37-48. Epub 2018 Sep 28 doi: 10.1007/s10549-018-4921-9. PMID: 30267249Free PMC Article
Breast Cancer in Men.
Giordano SH
N Engl J Med 2018 Jun 14;378(24):2311-2320. doi: 10.1056/NEJMra1707939. PMID: 29897847
Breast cancer personalized medicine: challenges and opportunities.
Coleman WB
Am J Pathol 2013 Oct;183(4):1036-1037. Epub 2013 Aug 23 doi: 10.1016/j.ajpath.2013.08.001. PMID: 23978519
Male breast cancer--neglected tumour.
Otto F
Eur J Cancer 2011 Sep;47 Suppl 3:S340-1. doi: 10.1016/S0959-8049(11)70195-2. PMID: 21944007
Mammary fibromatosis.
Glazebrook KN, Reynolds CA
AJR Am J Roentgenol 2009 Sep;193(3):856-60. doi: 10.2214/AJR.08.1892. PMID: 19696302

Diagnosis

Diagnosis and Treatment of Breast Cancer in Men.
Zehr KR
Radiol Technol 2019 Sep;91(1):51M-61M. PMID: 31471487
Erysipelas carcinomatosum.
Vandersee S
Dtsch Arztebl Int 2019 Jan 7;116(1-2):22. doi: 10.3238/arztebl.2019.0022b. PMID: 30782312Free PMC Article
Breast Cancer in Men.
Giordano SH
N Engl J Med 2018 Jun 14;378(24):2311-2320. doi: 10.1056/NEJMra1707939. PMID: 29897847
Male breast cancer--neglected tumour.
Otto F
Eur J Cancer 2011 Sep;47 Suppl 3:S340-1. doi: 10.1016/S0959-8049(11)70195-2. PMID: 21944007
Mammary fibromatosis.
Glazebrook KN, Reynolds CA
AJR Am J Roentgenol 2009 Sep;193(3):856-60. doi: 10.2214/AJR.08.1892. PMID: 19696302

Therapy

Male Breast Cancer (MBC) - A Review.
AlFehaid M
Pol Przegl Chir 2023 Dec 30;95(6):24-30. PMID: 38058163
Diagnosis and Treatment of Breast Cancer in Men.
Zehr KR
Radiol Technol 2019 Sep;91(1):51M-61M. PMID: 31471487
Male breast cancer: a disease distinct from female breast cancer.
Gucalp A, Traina TA, Eisner JR, Parker JS, Selitsky SR, Park BH, Elias AD, Baskin-Bey ES, Cardoso F
Breast Cancer Res Treat 2019 Jan;173(1):37-48. Epub 2018 Sep 28 doi: 10.1007/s10549-018-4921-9. PMID: 30267249Free PMC Article
The Genomic Landscape of Endocrine-Resistant Advanced Breast Cancers.
Razavi P, Chang MT, Xu G, Bandlamudi C, Ross DS, Vasan N, Cai Y, Bielski CM, Donoghue MTA, Jonsson P, Penson A, Shen R, Pareja F, Kundra R, Middha S, Cheng ML, Zehir A, Kandoth C, Patel R, Huberman K, Smyth LM, Jhaveri K, Modi S, Traina TA, Dang C, Zhang W, Weigelt B, Li BT, Ladanyi M, Hyman DM, Schultz N, Robson ME, Hudis C, Brogi E, Viale A, Norton L, Dickler MN, Berger MF, Iacobuzio-Donahue CA, Chandarlapaty S, Scaltriti M, Reis-Filho JS, Solit DB, Taylor BS, Baselga J
Cancer Cell 2018 Sep 10;34(3):427-438.e6. doi: 10.1016/j.ccell.2018.08.008. PMID: 30205045Free PMC Article
Breast Cancer in Men.
Giordano SH
N Engl J Med 2018 Jun 14;378(24):2311-2320. doi: 10.1056/NEJMra1707939. PMID: 29897847

Prognosis

Male Breast Cancer (MBC) - A Review.
AlFehaid M
Pol Przegl Chir 2023 Dec 30;95(6):24-30. PMID: 38058163
Diagnosis and Treatment of Breast Cancer in Men.
Zehr KR
Radiol Technol 2019 Sep;91(1):51M-61M. PMID: 31471487
Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†.
Cardoso F, Kyriakides S, Ohno S, Penault-Llorca F, Poortmans P, Rubio IT, Zackrisson S, Senkus E; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2019 Aug 1;30(8):1194-1220. doi: 10.1093/annonc/mdz173. PMID: 31161190
Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship.
Ruddy KJ, Winer EP
Ann Oncol 2013 Jun;24(6):1434-43. Epub 2013 Feb 20 doi: 10.1093/annonc/mdt025. PMID: 23425944
Male breast cancer.
Loerzel VW, Dow KH
Clin J Oncol Nurs 2004 Apr;8(2):191-2. doi: 10.1188/04.CJON.191-192. PMID: 15108421

Clinical prediction guides

BRCA1, BRCA2, and Associated Cancer Risks and Management for Male Patients: A Review.
Cheng HH, Shevach JW, Castro E, Couch FJ, Domchek SM, Eeles RA, Giri VN, Hall MJ, King MC, Lin DW, Loeb S, Morgan TM, Offit K, Pritchard CC, Schaeffer EM, Szymaniak BM, Vassy JL, Katona BW, Maxwell KN
JAMA Oncol 2024 Sep 1;10(9):1272-1281. doi: 10.1001/jamaoncol.2024.2185. PMID: 39052257
An updated review of epidemiology, risk factors, and management of male breast cancer.
Khan NAJ, Tirona M
Med Oncol 2021 Mar 15;38(4):39. doi: 10.1007/s12032-021-01486-x. PMID: 33721121
Management of Male Breast Cancer: ASCO Guideline.
Hassett MJ, Somerfield MR, Baker ER, Cardoso F, Kansal KJ, Kwait DC, Plichta JK, Ricker C, Roshal A, Ruddy KJ, Safer JD, Van Poznak C, Yung RL, Giordano SH
J Clin Oncol 2020 Jun 1;38(16):1849-1863. Epub 2020 Feb 14 doi: 10.1200/JCO.19.03120. PMID: 32058842
Bioinformatics analysis of prognostic significance of COL10A1 in breast cancer.
Zhang M, Chen H, Wang M, Bai F, Wu K
Biosci Rep 2020 Feb 28;40(2) doi: 10.1042/BSR20193286. PMID: 32043519Free PMC Article
Efficacy and Safety of Anti-Trop-2 Antibody Drug Conjugate Sacituzumab Govitecan (IMMU-132) in Heavily Pretreated Patients With Metastatic Triple-Negative Breast Cancer.
Bardia A, Mayer IA, Diamond JR, Moroose RL, Isakoff SJ, Starodub AN, Shah NC, O'Shaughnessy J, Kalinsky K, Guarino M, Abramson V, Juric D, Tolaney SM, Berlin J, Messersmith WA, Ocean AJ, Wegener WA, Maliakal P, Sharkey RM, Govindan SV, Goldenberg DM, Vahdat LT
J Clin Oncol 2017 Jul 1;35(19):2141-2148. Epub 2017 Mar 14 doi: 10.1200/JCO.2016.70.8297. PMID: 28291390Free PMC Article

Recent systematic reviews

Ultra-processed food consumption and cancer risk: A systematic review and meta-analysis.
Isaksen IM, Dankel SN
Clin Nutr 2023 Jun;42(6):919-928. Epub 2023 Mar 30 doi: 10.1016/j.clnu.2023.03.018. PMID: 37087831
Systematic Review and Meta-Analysis of the Impact of Bariatric Surgery on Future Cancer Risk.
Wilson RB, Lathigara D, Kaushal D
Int J Mol Sci 2023 Mar 24;24(7) doi: 10.3390/ijms24076192. PMID: 37047163Free PMC Article
Plant-Based Diets and Cancer Prognosis: a Review of Recent Research.
Hardt L, Mahamat-Saleh Y, Aune D, Schlesinger S
Curr Nutr Rep 2022 Dec;11(4):695-716. Epub 2022 Sep 23 doi: 10.1007/s13668-022-00440-1. PMID: 36138327Free PMC Article
The effects of physical activity on cortisol and sleep: A systematic review and meta-analysis.
De Nys L, Anderson K, Ofosu EF, Ryde GC, Connelly J, Whittaker AC
Psychoneuroendocrinology 2022 Sep;143:105843. Epub 2022 Jun 24 doi: 10.1016/j.psyneuen.2022.105843. PMID: 35777076
Metabolic syndrome and risk of cancer: a systematic review and meta-analysis.
Esposito K, Chiodini P, Colao A, Lenzi A, Giugliano D
Diabetes Care 2012 Nov;35(11):2402-11. doi: 10.2337/dc12-0336. PMID: 23093685Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...