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Panic disorder with agoraphobia

MedGen UID:
472969
•Concept ID:
C0236800
•
Mental or Behavioral Dysfunction
Synonyms: Panic Disorder with Agoraphobia; panic disorder with agoraphobia
SNOMED CT: Panic disorder with agoraphobia (35607004)
 
Monarch Initiative: MONDO:0044144

Definition

A disorder in which an individual experiences recurrent, unexpected panic attacks and persistent concern about having additional panic attacks. Agoraphobia is a component of this disorder. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPanic disorder with agoraphobia

Professional guidelines

PubMed

Panic disorder with agoraphobia from a behavioral neuroscience perspective: Applying the research principles formulated by the Research Domain Criteria (RDoC) initiative.
Hamm AO, Richter J, Pané-Farré C, Westphal D, Wittchen HU, Vossbeck-Elsebusch AN, Gerlach AL, Gloster AT, Ströhle A, Lang T, Kircher T, Gerdes AB, Alpers GW, Reif A, Deckert J
Psychophysiology 2016 Mar;53(3):312-22. doi: 10.1111/psyp.12553. PMID: 26877119
Diagnosis and treatment of agoraphobia with panic disorder.
Perugi G, Frare F, Toni C
CNS Drugs 2007;21(9):741-64. doi: 10.2165/00023210-200721090-00004. PMID: 17696574
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders.
Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF
Am J Psychiatry 1992 Jul;149(7):936-43. doi: 10.1176/ajp.149.7.936. PMID: 1609875

Curated

UK NICE Clinical Guideline CG113, Generalised anxiety disorder and panic disorder in adults: management

Recent clinical studies

Etiology

Bipolar disorder comorbidity in patients with obsessive-compulsive disorder: Prevalence and predictors.
Domingues-Castro MS, Torresan RC, Shavitt RG, Fontenelle LF, Ferrão YA, Rosário MC, Torres AR
J Affect Disord 2019 Sep 1;256:324-330. Epub 2019 Jun 7 doi: 10.1016/j.jad.2019.06.018. PMID: 31201983
Long-term disability in anxiety disorders.
Hendriks SM, Spijker J, Licht CM, Hardeveld F, de Graaf R, Batelaan NM, Penninx BW, Beekman AT
BMC Psychiatry 2016 Jul 19;16:248. doi: 10.1186/s12888-016-0946-y. PMID: 27431392Free PMC Article
Panic disorder with agoraphobia from a behavioral neuroscience perspective: Applying the research principles formulated by the Research Domain Criteria (RDoC) initiative.
Hamm AO, Richter J, Pané-Farré C, Westphal D, Wittchen HU, Vossbeck-Elsebusch AN, Gerlach AL, Gloster AT, Ströhle A, Lang T, Kircher T, Gerdes AB, Alpers GW, Reif A, Deckert J
Psychophysiology 2016 Mar;53(3):312-22. doi: 10.1111/psyp.12553. PMID: 26877119
Personality disorders and anxiety disorders: what is the relationship?
Latas M, Milovanovic S
Curr Opin Psychiatry 2014 Jan;27(1):57-61. doi: 10.1097/YCO.0000000000000025. PMID: 24270478
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders.
Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF
Am J Psychiatry 1992 Jul;149(7):936-43. doi: 10.1176/ajp.149.7.936. PMID: 1609875

Diagnosis

Impulsivity across psychiatric disorders in young adults.
Crisp ZC, Grant JE
Compr Psychiatry 2024 Apr;130:152449. Epub 2024 Jan 4 doi: 10.1016/j.comppsych.2023.152449. PMID: 38184857
Panic attack provocation in panic disorder patients with a computer simulation.
Freire RC, Ferreira-Garcia R, Cabo MC, Martins RM, Nardi AE
J Affect Disord 2020 Mar 1;264:498-505. Epub 2019 Nov 13 doi: 10.1016/j.jad.2019.11.081. PMID: 31786029
Disability in anxiety disorders.
Hendriks SM, Spijker J, Licht CM, Beekman AT, Hardeveld F, de Graaf R, Batelaan NM, Penninx BW
J Affect Disord 2014 Sep;166:227-33. Epub 2014 May 10 doi: 10.1016/j.jad.2014.05.006. PMID: 25012435
Personality disorders and anxiety disorders: what is the relationship?
Latas M, Milovanovic S
Curr Opin Psychiatry 2014 Jan;27(1):57-61. doi: 10.1097/YCO.0000000000000025. PMID: 24270478
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders.
Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF
Am J Psychiatry 1992 Jul;149(7):936-43. doi: 10.1176/ajp.149.7.936. PMID: 1609875

Therapy

Self-guided digital treatment with virtual reality for panic disorder and agoraphobia: a study protocol for a randomized controlled trial.
Planert J, Machulska A, Hildebrand AS, Roesmann K, Otto E, Klucken T
Trials 2022 May 21;23(1):426. doi: 10.1186/s13063-022-06366-x. PMID: 35597959Free PMC Article
Cognitive models for panic disorder with agoraphobia: A study of disaggregated within-person effects.
Hoffart A
J Consult Clin Psychol 2016 Sep;84(9):839-844. doi: 10.1037/ccp0000114. PMID: 27123977
Panic disorder with agoraphobia from a behavioral neuroscience perspective: Applying the research principles formulated by the Research Domain Criteria (RDoC) initiative.
Hamm AO, Richter J, Pané-Farré C, Westphal D, Wittchen HU, Vossbeck-Elsebusch AN, Gerlach AL, Gloster AT, Ströhle A, Lang T, Kircher T, Gerdes AB, Alpers GW, Reif A, Deckert J
Psychophysiology 2016 Mar;53(3):312-22. doi: 10.1111/psyp.12553. PMID: 26877119
Cognitive-behavioral therapy for panic disorder with agoraphobia in older people: a comparison with younger patients.
Hendriks GJ, Kampman M, Keijsers GP, Hoogduin CA, Voshaar RC
Depress Anxiety 2014 Aug;31(8):669-77. Epub 2014 May 27 doi: 10.1002/da.22274. PMID: 24867666
Use of benzodiazepines in panic disorder.
Davidson JR
J Clin Psychiatry 1997;58 Suppl 2:26-8; discussion 29-31. PMID: 9078991

Prognosis

Panic attack provocation in panic disorder patients with a computer simulation.
Freire RC, Ferreira-Garcia R, Cabo MC, Martins RM, Nardi AE
J Affect Disord 2020 Mar 1;264:498-505. Epub 2019 Nov 13 doi: 10.1016/j.jad.2019.11.081. PMID: 31786029
Bipolar disorder comorbidity in patients with obsessive-compulsive disorder: Prevalence and predictors.
Domingues-Castro MS, Torresan RC, Shavitt RG, Fontenelle LF, Ferrão YA, Rosário MC, Torres AR
J Affect Disord 2019 Sep 1;256:324-330. Epub 2019 Jun 7 doi: 10.1016/j.jad.2019.06.018. PMID: 31201983
Long-term disability in anxiety disorders.
Hendriks SM, Spijker J, Licht CM, Hardeveld F, de Graaf R, Batelaan NM, Penninx BW, Beekman AT
BMC Psychiatry 2016 Jul 19;16:248. doi: 10.1186/s12888-016-0946-y. PMID: 27431392Free PMC Article
Agoraphobia With and Without Panic Disorder: A 20-Year Follow-up of Integrated Exposure and Psychodynamic Therapy.
Hoffart A, Hedley LM, Svanøe K, Langkaas TF, Sexton H
J Nerv Ment Dis 2016 Feb;204(2):100-7. doi: 10.1097/NMD.0000000000000419. PMID: 26588081
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders.
Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF
Am J Psychiatry 1992 Jul;149(7):936-43. doi: 10.1176/ajp.149.7.936. PMID: 1609875

Clinical prediction guides

Impulsivity across psychiatric disorders in young adults.
Crisp ZC, Grant JE
Compr Psychiatry 2024 Apr;130:152449. Epub 2024 Jan 4 doi: 10.1016/j.comppsych.2023.152449. PMID: 38184857
Panic attack provocation in panic disorder patients with a computer simulation.
Freire RC, Ferreira-Garcia R, Cabo MC, Martins RM, Nardi AE
J Affect Disord 2020 Mar 1;264:498-505. Epub 2019 Nov 13 doi: 10.1016/j.jad.2019.11.081. PMID: 31786029
Bipolar disorder comorbidity in patients with obsessive-compulsive disorder: Prevalence and predictors.
Domingues-Castro MS, Torresan RC, Shavitt RG, Fontenelle LF, Ferrão YA, Rosário MC, Torres AR
J Affect Disord 2019 Sep 1;256:324-330. Epub 2019 Jun 7 doi: 10.1016/j.jad.2019.06.018. PMID: 31201983
Long-term disability in anxiety disorders.
Hendriks SM, Spijker J, Licht CM, Hardeveld F, de Graaf R, Batelaan NM, Penninx BW, Beekman AT
BMC Psychiatry 2016 Jul 19;16:248. doi: 10.1186/s12888-016-0946-y. PMID: 27431392Free PMC Article
Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders.
Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF
Am J Psychiatry 1992 Jul;149(7):936-43. doi: 10.1176/ajp.149.7.936. PMID: 1609875

Recent systematic reviews

Combination of psychotherapy and benzodiazepines versus either therapy alone for panic disorder: a systematic review.
Watanabe N, Churchill R, Furukawa TA
BMC Psychiatry 2007 May 14;7:18. doi: 10.1186/1471-244X-7-18. PMID: 17501985Free PMC Article

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    Curated

    • NICE, 2020
      UK NICE Clinical Guideline CG113, Generalised anxiety disorder and panic disorder in adults: management

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    Reviews

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