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Obsessional thoughts

MedGen UID:
115928
•Concept ID:
C0233697
•
Mental or Behavioral Dysfunction
Synonyms: Obsession; Obsessions
SNOMED CT: Obsessional ruminations (67698009); Obsessional thoughts (67698009)

Professional guidelines

PubMed

Is the hierarchy necessary? Gradual versus variable exposure intensity in the treatment of unacceptable obsessional thoughts.
Jacoby RJ, Abramowitz JS, Blakey SM, Reuman L
J Behav Ther Exp Psychiatry 2019 Sep;64:54-63. Epub 2019 Feb 26 doi: 10.1016/j.jbtep.2019.02.008. PMID: 30851653
Skoptic syndrome: the treatment of an obsessional gender dysphoria with lithium carbonate and psychotherapy.
Coleman E, Cesnik J
Am J Psychother 1990 Apr;44(2):204-17. doi: 10.1176/appi.psychotherapy.1990.44.2.204. PMID: 2114800
Looking into a deaf child's future. A brief treatment approach.
Harvey MA, Green CL
Am Ann Deaf 1990 Dec;135(5):364-70. doi: 10.1353/aad.2012.0457. PMID: 2091450

Recent clinical studies

Etiology

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD).
Elliott SJ, Marshall D, Morley K, Uphoff E, Kumar M, Meader N
Cochrane Database Syst Rev 2021 Sep 3;9(9):CD013173. doi: 10.1002/14651858.CD013173.pub2. PMID: 34693989Free PMC Article
Resting-state connectivity within and across neural circuits in anorexia nervosa.
Uniacke B, Wang Y, Biezonski D, Sussman T, Lee S, Posner J, Steinglass J
Brain Behav 2019 Jan;9(1):e01205. Epub 2018 Dec 27 doi: 10.1002/brb3.1205. PMID: 30590873Free PMC Article
OCD cognitions and symptoms in different religious contexts.
Yorulmaz O, Gençöz T, Woody S
J Anxiety Disord 2009 Apr;23(3):401-6. Epub 2008 Nov 18 doi: 10.1016/j.janxdis.2008.11.001. PMID: 19108983
Female stalkers and their victims.
Meloy JR, Boyd C
J Am Acad Psychiatry Law 2003;31(2):211-9. PMID: 12875500
Obsessive-compulsive symptoms in pregnancy and the puerperium: a review of the literature.
Abramowitz JS, Schwartz SA, Moore KM, Luenzmann KR
J Anxiety Disord 2003;17(4):461-78. doi: 10.1016/s0887-6185(02)00206-2. PMID: 12826092

Diagnosis

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD).
Elliott SJ, Marshall D, Morley K, Uphoff E, Kumar M, Meader N
Cochrane Database Syst Rev 2021 Sep 3;9(9):CD013173. doi: 10.1002/14651858.CD013173.pub2. PMID: 34693989Free PMC Article
Efficacy and safety of dasotraline in adults with binge-eating disorder: a randomized, placebo-controlled, fixed-dose clinical trial.
Grilo CM, McElroy SL, Hudson JI, Tsai J, Navia B, Goldman R, Deng L, Kent J, Loebel A
CNS Spectr 2021 Oct;26(5):481-490. Epub 2020 May 19 doi: 10.1017/S1092852920001406. PMID: 32423512Free PMC Article
OCD cognitions and symptoms in different religious contexts.
Yorulmaz O, Gençöz T, Woody S
J Anxiety Disord 2009 Apr;23(3):401-6. Epub 2008 Nov 18 doi: 10.1016/j.janxdis.2008.11.001. PMID: 19108983
Obsessive-compulsive symptoms in pregnancy and the puerperium: a review of the literature.
Abramowitz JS, Schwartz SA, Moore KM, Luenzmann KR
J Anxiety Disord 2003;17(4):461-78. doi: 10.1016/s0887-6185(02)00206-2. PMID: 12826092
Compulsivity and superstitiousness.
Frost RO, Krause MS, McMahon MJ, Peppe J, Evans M, McPhee AE, Holden M
Behav Res Ther 1993 May;31(4):423-5. doi: 10.1016/0005-7967(93)90101-y. PMID: 8512543

Therapy

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD).
Elliott SJ, Marshall D, Morley K, Uphoff E, Kumar M, Meader N
Cochrane Database Syst Rev 2021 Sep 3;9(9):CD013173. doi: 10.1002/14651858.CD013173.pub2. PMID: 34693989Free PMC Article
Efficacy and safety of dasotraline in adults with binge-eating disorder: a randomized, placebo-controlled, fixed-dose clinical trial.
Grilo CM, McElroy SL, Hudson JI, Tsai J, Navia B, Goldman R, Deng L, Kent J, Loebel A
CNS Spectr 2021 Oct;26(5):481-490. Epub 2020 May 19 doi: 10.1017/S1092852920001406. PMID: 32423512Free PMC Article
Adherence to exposure and response prevention as a predictor of improvement in obsessive-compulsive symptom dimensions.
Ojalehto HJ, Abramowitz JS, Hellberg SN, Buchholz JL, Twohig MP
J Anxiety Disord 2020 May;72:102210. Epub 2020 Mar 12 doi: 10.1016/j.janxdis.2020.102210. PMID: 32208231
Appraisals of obsessional thoughts in normal samples.
Corcoran KM, Woody SR
Behav Res Ther 2008 Jan;46(1):71-83. Epub 2007 Oct 22 doi: 10.1016/j.brat.2007.10.007. PMID: 18093572
The role of serotonin in craving: from basic research to human studies.
Ciccocioppo R
Alcohol Alcohol 1999 Mar-Apr;34(2):244-53. doi: 10.1093/alcalc/34.2.244. PMID: 10344784

Prognosis

Cross-sectional direct and indirect relationships between the corrupted feared self and obsessive-compulsive symptoms in a clinical sample: The role of mental contamination.
Khosravani V, Samimi Ardestani SM, Wong SF, Moulding R, Aardema F, Sharifibastan F, Aminaee M
Br J Clin Psychol 2023 Nov;62(4):800-815. Epub 2023 Sep 16 doi: 10.1111/bjc.12440. PMID: 37715987
Adherence to exposure and response prevention as a predictor of improvement in obsessive-compulsive symptom dimensions.
Ojalehto HJ, Abramowitz JS, Hellberg SN, Buchholz JL, Twohig MP
J Anxiety Disord 2020 May;72:102210. Epub 2020 Mar 12 doi: 10.1016/j.janxdis.2020.102210. PMID: 32208231
A case of an unusual presentation of obsessive compulsive disorder in an adolescent.
Rohanachandra YM, Vipulanandan S
Asian J Psychiatr 2019 Jun;43:34-36. Epub 2019 May 3 doi: 10.1016/j.ajp.2019.05.008. PMID: 31078093
Resting-state connectivity within and across neural circuits in anorexia nervosa.
Uniacke B, Wang Y, Biezonski D, Sussman T, Lee S, Posner J, Steinglass J
Brain Behav 2019 Jan;9(1):e01205. Epub 2018 Dec 27 doi: 10.1002/brb3.1205. PMID: 30590873Free PMC Article
Predictors and consequences of health anxiety symptoms: a novel twin modeling study.
López-Solà C, Bui M, Hopper JL, Fontenelle LF, Davey CG, Pantelis C, Alonso P, van den Heuvel OA, Harrison BJ
Acta Psychiatr Scand 2018 Mar;137(3):241-251. Epub 2018 Jan 15 doi: 10.1111/acps.12850. PMID: 29336012

Clinical prediction guides

Cross-sectional direct and indirect relationships between the corrupted feared self and obsessive-compulsive symptoms in a clinical sample: The role of mental contamination.
Khosravani V, Samimi Ardestani SM, Wong SF, Moulding R, Aardema F, Sharifibastan F, Aminaee M
Br J Clin Psychol 2023 Nov;62(4):800-815. Epub 2023 Sep 16 doi: 10.1111/bjc.12440. PMID: 37715987
Eating disorders with over-exercise: A cross-sectional analysis of the mediational role of problematic usage of the internet in young people.
Ioannidis K, Hook RW, Grant JE, Czabanowska K, Roman-Urrestarazu A, Chamberlain SR
J Psychiatr Res 2021 Jan;132:215-222. Epub 2020 Nov 4 doi: 10.1016/j.jpsychires.2020.11.004. PMID: 33189357Free PMC Article
Efficacy and safety of dasotraline in adults with binge-eating disorder: a randomized, placebo-controlled, fixed-dose clinical trial.
Grilo CM, McElroy SL, Hudson JI, Tsai J, Navia B, Goldman R, Deng L, Kent J, Loebel A
CNS Spectr 2021 Oct;26(5):481-490. Epub 2020 May 19 doi: 10.1017/S1092852920001406. PMID: 32423512Free PMC Article
Believing is seeing: an fMRI study of thought-action fusion in healthy male adults.
Lee SW, Kim E, Chung Y, Cha H, Song H, Chang Y, Lee SJ
Brain Imaging Behav 2021 Feb;15(1):300-310. doi: 10.1007/s11682-020-00257-y. PMID: 32125617
Adherence to exposure and response prevention as a predictor of improvement in obsessive-compulsive symptom dimensions.
Ojalehto HJ, Abramowitz JS, Hellberg SN, Buchholz JL, Twohig MP
J Anxiety Disord 2020 May;72:102210. Epub 2020 Mar 12 doi: 10.1016/j.janxdis.2020.102210. PMID: 32208231

Recent systematic reviews

Behavioural and cognitive behavioural therapy for obsessive compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD).
Elliott SJ, Marshall D, Morley K, Uphoff E, Kumar M, Meader N
Cochrane Database Syst Rev 2021 Sep 3;9(9):CD013173. doi: 10.1002/14651858.CD013173.pub2. PMID: 34693989Free PMC Article

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