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Hydrosalpinx

MedGen UID:: 526227
•Concept ID:: C0221376
•: Disease or Syndrome

Synonyms:	blocked fallopian tube; fallopian tube obstruction; hydrosalpinx
SNOMED CT:	Hydrosalpinx (21711003)

HPO:	HP:6000146
Monarch Initiative:	MONDO:0600025

Definition

Hydrosalpinx is a distension or dilatation of the fallopian tube in the presence of a distal tubal occlusion. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVHydrosalpinx

Abnormality of the genitourinary system
- Abnormality of the genital system
  - Abnormal reproductive system morphology
    - Abnormality of the female genitalia
      - Abnormal morphology of female internal genitalia
        Abnormal fallopian tube morphology
        Hydrosalpinx

Professional guidelines

PubMed

Pregnancy outcome of in vitro fertilization after Essure and laparoscopic management of hydrosalpinx: a systematic review and meta-analysis.

Xu B, Zhang Q, Zhao J, Wang Y, Xu D, Li Y
Fertil Steril 2017 Jul;108(1):84-95.e5. Epub 2017 Jun 1 doi: 10.1016/j.fertnstert.2017.05.005. PMID: 28579408

Best practice in management of paediatric and adolescent hydrosalpinges: a systematic review.

Kazmi Z, Gupta S
Eur J Obstet Gynecol Reprod Biol 2015 Dec;195:40-51. Epub 2015 Oct 8 doi: 10.1016/j.ejogrb.2015.09.042. PMID: 26476798

Implantation failure: molecular mechanisms and clinical treatment.

Cakmak H, Taylor HS
Hum Reprod Update 2011 Mar-Apr;17(2):242-53. Epub 2010 Aug 21 doi: 10.1093/humupd/dmq037. PMID: 20729534 Free PMC Article

See all (40)

Recent clinical studies

Etiology

Surgical disorders in pediatric and adolescent gynecology: Adnexal abnormalities.

Mentessidou A, Mirilas P
Int J Gynaecol Obstet 2023 Jun;161(3):702-710. Epub 2022 Nov 26 doi: 10.1002/ijgo.14574. PMID: 36373872

Individualized luteal phase support normalizes live birth rate in women with low progesterone levels on the day of embryo transfer in artificial endometrial preparation cycles.

Labarta E, Mariani G, Rodríguez-Varela C, Bosch E
Fertil Steril 2022 Jan;117(1):96-103. Epub 2021 Sep 20 doi: 10.1016/j.fertnstert.2021.08.040. PMID: 34548167

Transvaginal US of Endometriosis: Looking Beyond the Endometrioma with a Dedicated Protocol.

Collins BG, Ankola A, Gola S, McGillen KL
Radiographics 2019 Sep-Oct;39(5):1549-1568. doi: 10.1148/rg.2019190045. PMID: 31498746

The Effect of Salpingectomy on Ovarian Function.

Kotlyar A, Gingold J, Shue S, Falcone T
J Minim Invasive Gynecol 2017 May-Jun;24(4):563-578. Epub 2017 Feb 20 doi: 10.1016/j.jmig.2017.02.014. PMID: 28223181

Defective endometrial receptivity.

Revel A
Fertil Steril 2012 May;97(5):1028-32. doi: 10.1016/j.fertnstert.2012.03.039. PMID: 22542142

See all (316)

Diagnosis

Surgical disorders in pediatric and adolescent gynecology: Adnexal abnormalities.

Mentessidou A, Mirilas P
Int J Gynaecol Obstet 2023 Jun;161(3):702-710. Epub 2022 Nov 26 doi: 10.1002/ijgo.14574. PMID: 36373872

The "cogwheel" sign of hydrosalpinx.

Della Grotta LM, Dyer RB, Holbert BL
Abdom Radiol (NY) 2019 Oct;44(10):3486-3487. doi: 10.1007/s00261-019-02144-7. PMID: 31346740

Hydrosalpinx: Tubal surgery or in vitro fertilisation? An everlasting dilemma nowadays; a narrative review.

Daniilidis A, Balaouras D, Chitzios D, Theodoridis T, Assimakopoulos E
J Obstet Gynaecol 2017 Jul;37(5):550-556. Epub 2017 Mar 21 doi: 10.1080/01443615.2017.1287685. PMID: 28325120

Magnetic resonance imaging structured reporting in infertility.

Montoliu-Fornas G, Martí-Bonmatí L
Fertil Steril 2016 Jun;105(6):1421-31. Epub 2016 Apr 19 doi: 10.1016/j.fertnstert.2016.04.005. PMID: 27105717

Laparoscopic management of hydrosalpinx.

Bontis JN, Theodoridis TD
Ann N Y Acad Sci 2006 Dec;1092:199-210. doi: 10.1196/annals.1365.017. PMID: 17308145

See all (298)

Therapy

Individualized luteal phase support normalizes live birth rate in women with low progesterone levels on the day of embryo transfer in artificial endometrial preparation cycles.

Labarta E, Mariani G, Rodríguez-Varela C, Bosch E
Fertil Steril 2022 Jan;117(1):96-103. Epub 2021 Sep 20 doi: 10.1016/j.fertnstert.2021.08.040. PMID: 34548167

The Effect of Salpingectomy on Ovarian Function.

Kotlyar A, Gingold J, Shue S, Falcone T
J Minim Invasive Gynecol 2017 May-Jun;24(4):563-578. Epub 2017 Feb 20 doi: 10.1016/j.jmig.2017.02.014. PMID: 28223181

Defective endometrial receptivity.

Revel A
Fertil Steril 2012 May;97(5):1028-32. doi: 10.1016/j.fertnstert.2012.03.039. PMID: 22542142

Hysterosalpingography: a reemerging study.

Simpson WL Jr, Beitia LG, Mester J
Radiographics 2006 Mar-Apr;26(2):419-31. doi: 10.1148/rg.262055109. PMID: 16549607

Hydrosalpinx and ART: hydrosalpinx--functional surgery or salpingectomy?

Puttemans P, Campo R, Gordts S, Brosens I
Hum Reprod 2000 Jul;15(7):1427-30. doi: 10.1093/humrep/15.7.1427. PMID: 10875845

See all (173)

Prognosis

MRI in pelvic inflammatory disease: a pictorial review.

Czeyda-Pommersheim F, Kalb B, Costello J, Liau J, Meshksar A, Arif Tiwari H, Martin D
Abdom Radiol (NY) 2017 Mar;42(3):935-950. doi: 10.1007/s00261-016-1004-4. PMID: 27933478

Thirteen cases of isolated tubal torsions associated with hydrosalpinx in children and adolescents, proposal for conservative management: retrospective review and literature survey.

Boukaidi SA, Delotte J, Steyaert H, Valla JS, Sattonet C, Bouaziz J, Bongain A
J Pediatr Surg 2011 Jul;46(7):1425-31. doi: 10.1016/j.jpedsurg.2011.01.033. PMID: 21763846

Hydrosalpinx and assisted reproduction: options and rationale for treatment.

Zeyneloglu HB
Curr Opin Obstet Gynecol 2001 Jun;13(3):281-6. doi: 10.1097/00001703-200106000-00006. PMID: 11396651

A decade of salpingoscopy.

Puttemans PJ, De Bruyne F, Heylen SM
Eur J Obstet Gynecol Reprod Biol 1998 Dec;81(2):197-206. doi: 10.1016/s0301-2115(98)00191-2. PMID: 9989866

The significance of hydrosalpinx in in vitro fertilization.

Nackley AC, Muasher SJ
Fertil Steril 1998 Mar;69(3):373-84. doi: 10.1016/s0015-0282(97)00484-6. PMID: 9531862

See all (130)

Clinical prediction guides

Optimizing intrauterine insemination and spontaneous conception in women with unilateral hydrosalpinx or tubal pathology: A systematic review and narrative synthesis.

Yip JY, Kanneganti A, Binte Ahmad N, Lim MXK, Chew SLS, Huang Z
Eur J Obstet Gynecol Reprod Biol 2023 Jul;286:135-144. Epub 2023 May 23 doi: 10.1016/j.ejogrb.2023.05.024. PMID: 37267890

Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq.

Ulrich ND, Shen YC, Ma Q, Yang K, Hannum DF, Jones A, Machlin J, Randolph JF Jr, Smith YR, Schon SB, Shikanov A, Marsh EE, Lieberman R, Gurczynski SJ, Moore BB, Li JZ, Hammoud S
Dev Cell 2022 Apr 11;57(7):914-929.e7. Epub 2022 Mar 22 doi: 10.1016/j.devcel.2022.02.017. PMID: 35320732 Free PMC Article

Individualized luteal phase support normalizes live birth rate in women with low progesterone levels on the day of embryo transfer in artificial endometrial preparation cycles.

Labarta E, Mariani G, Rodríguez-Varela C, Bosch E
Fertil Steril 2022 Jan;117(1):96-103. Epub 2021 Sep 20 doi: 10.1016/j.fertnstert.2021.08.040. PMID: 34548167

Salpingostomy in the treatment of hydrosalpinx: a systematic review and meta-analysis.

Chu J, Harb HM, Gallos ID, Dhillon R, Al-Rshoud FM, Robinson L, Coomarasamy A
Hum Reprod 2015 Aug;30(8):1882-95. Epub 2015 Jun 16 doi: 10.1093/humrep/dev135. PMID: 26082479

Salpingectomy and proximal tubal occlusion for hydrosalpinx prior to in vitro fertilization: a meta-analysis of randomized controlled trials.

Zhang Y, Sun Y, Guo Y, Li TC, Duan H
Obstet Gynecol Surv 2015 Jan;70(1):33-8. doi: 10.1097/OGX.0000000000000139. PMID: 25616345

See all (151)

Recent systematic reviews

Optimizing intrauterine insemination and spontaneous conception in women with unilateral hydrosalpinx or tubal pathology: A systematic review and narrative synthesis.

Yip JY, Kanneganti A, Binte Ahmad N, Lim MXK, Chew SLS, Huang Z
Eur J Obstet Gynecol Reprod Biol 2023 Jul;286:135-144. Epub 2023 May 23 doi: 10.1016/j.ejogrb.2023.05.024. PMID: 37267890

Effect of salpingectomy on ovarian reserve: A systematic review and meta-analysis.

Kobayashi M, Kitahara Y, Hasegawa Y, Tsukui Y, Hiraishi H, Iwase A
J Obstet Gynaecol Res 2022 Jul;48(7):1513-1522. Epub 2022 May 27 doi: 10.1111/jog.15316. PMID: 35624527

Hydrosalpinx and pregnancy loss: a systematic review and meta-analysis.

Harb H, Al-Rshoud F, Karunakaran B, Gallos ID, Coomarasamy A
Reprod Biomed Online 2019 Mar;38(3):427-441. Epub 2018 Dec 25 doi: 10.1016/j.rbmo.2018.12.020. PMID: 30665848

Pregnancy outcome of in vitro fertilization after Essure and laparoscopic management of hydrosalpinx: a systematic review and meta-analysis.

Xu B, Zhang Q, Zhao J, Wang Y, Xu D, Li Y
Fertil Steril 2017 Jul;108(1):84-95.e5. Epub 2017 Jun 1 doi: 10.1016/j.fertnstert.2017.05.005. PMID: 28579408

Salpingostomy in the treatment of hydrosalpinx: a systematic review and meta-analysis.

Chu J, Harb HM, Gallos ID, Dhillon R, Al-Rshoud FM, Robinson L, Coomarasamy A
Hum Reprod 2015 Aug;30(8):1882-95. Epub 2015 Jun 16 doi: 10.1093/humrep/dev135. PMID: 26082479

See all (24)

MedGen

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Hydrosalpinx

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Clinical resources

Practice guidelines

Consumer resources

Reviews

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