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Diplegia

MedGen UID:
472941
Concept ID:
C0221165
Disease or Syndrome
Synonym: Bilateral paralysis
SNOMED CT: Diplegia (6481005); Bilateral paralysis (6481005)

Definition

Paralysis affecting corresponding parts on both sides of the body. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiplegia

Professional guidelines

PubMed

Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Nicolini-Panisson RD, Tedesco AP, Folle MR, Donadio MVF
Rev Paul Pediatr 2018 Jan-Mar;36(1):9. Epub 2018 Jan 15 doi: 10.1590/1984-0462/;2018;36;1;00005. PMID: 29412426Free PMC Article
Huntsman R, Lemire E, Norton J, Dzus A, Blakley P, Hasal S
Arch Dis Child 2015 May;100(5):500-4. Epub 2014 Nov 18 doi: 10.1136/archdischild-2014-307443. PMID: 25700542

Recent clinical studies

Etiology

Peia F, Veiga NC, Gomes AP, Santos BND, Marques NMS, Glória IPDS, Goulardins JB
Pediatr Phys Ther 2023 Apr 1;35(2):202-210. Epub 2023 Mar 3 doi: 10.1097/PEP.0000000000000999. PMID: 36867588
Hussein ZA, Salem IA, Ali MS
J Musculoskelet Neuronal Interact 2019 Dec 1;19(4):500-506. PMID: 31789301Free PMC Article
Arvedson JC
Eur J Clin Nutr 2013 Dec;67 Suppl 2:S9-12. doi: 10.1038/ejcn.2013.224. PMID: 24301008
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151
Accardo J, Kammann H, Hoon AH Jr
J Pediatr 2004 Aug;145(2 Suppl):S19-27. doi: 10.1016/j.jpeds.2004.05.018. PMID: 15292883

Diagnosis

Sinibaldi L, Garone G, Mandarino A, Iarossi G, Chioma L, Dentici ML, Merla G, Agolini E, Micalizzi A, Mancini C, Niceta M, Macchiaiolo M, Diodato D, Onesimo R, Blandino R, Delogu AB, De Rosa G, Trevisan V, Iademarco M, Zampino G, Tartaglia M, Novelli A, Bartuli A, Digilio MC, Calcagni G
Clin Genet 2023 Nov;104(5):528-541. Epub 2023 Jul 17 doi: 10.1111/cge.14404. PMID: 37455656
des Portes V
Handb Clin Neurol 2013;111:297-306. doi: 10.1016/B978-0-444-52891-9.00035-X. PMID: 23622180
Dutra LA, Braga-Neto P, Pedroso JL, Povoas Barsottini OG
Adv Exp Med Biol 2012;724:344-50. doi: 10.1007/978-1-4614-0653-2_26. PMID: 22411255
Gordon N
Dev Med Child Neurol 2007 Feb;49(2):152-4. doi: 10.1111/j.1469-8749.2007.00152.x. PMID: 17254005
Eliasson AC, Krumlinde-Sundholm L, Rösblad B, Beckung E, Arner M, Ohrvall AM, Rosenbaum P
Dev Med Child Neurol 2006 Jul;48(7):549-54. doi: 10.1017/S0012162206001162. PMID: 16780622

Therapy

Chowdhury S, Chowdhury S
Int J Immunopathol Pharmacol 2023 Jan-Dec;37:3946320231199349. doi: 10.1177/03946320231199349. PMID: 37681361Free PMC Article
Matusiak-Wieczorek E, Dziankowska-Zaborszczyk E, Synder M, Borowski A
Int J Environ Res Public Health 2020 Sep 19;17(18) doi: 10.3390/ijerph17186846. PMID: 32961681Free PMC Article
Hussein ZA, Salem IA, Ali MS
J Musculoskelet Neuronal Interact 2019 Dec 1;19(4):500-506. PMID: 31789301Free PMC Article
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Hyland K, Shoffner J, Heales SJ
J Inherit Metab Dis 2010 Oct;33(5):563-70. Epub 2010 Jul 29 doi: 10.1007/s10545-010-9159-6. PMID: 20668945

Prognosis

Spiegel R, Schwahn BC, Squires L, Confer N
J Inherit Metab Dis 2022 May;45(3):456-469. Epub 2022 Mar 3 doi: 10.1002/jimd.12488. PMID: 35192225Free PMC Article
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Cho KH, Shim SH, Kim M
Clin Genet 2018 Apr;93(4):721-730. Epub 2017 Sep 17 doi: 10.1111/cge.13058. PMID: 28543186
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151
Dabney KW, Lipton GE, Miller F
Curr Opin Pediatr 1997 Feb;9(1):81-8. doi: 10.1097/00008480-199702000-00017. PMID: 9088760

Clinical prediction guides

Sileo FG, Zöllner J, D'Antonio F, Islam S, Papageorghiou AT, Khalil A
Ultrasound Obstet Gynecol 2022 May;59(5):585-595. doi: 10.1002/uog.24766. PMID: 34529308
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Echenne B, Bassez G
Handb Clin Neurol 2013;113:1387-93. doi: 10.1016/B978-0-444-59565-2.00009-5. PMID: 23622362
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151
Eliasson AC, Krumlinde-Sundholm L, Rösblad B, Beckung E, Arner M, Ohrvall AM, Rosenbaum P
Dev Med Child Neurol 2006 Jul;48(7):549-54. doi: 10.1017/S0012162206001162. PMID: 16780622

Recent systematic reviews

Peia F, Veiga NC, Gomes AP, Santos BND, Marques NMS, Glória IPDS, Goulardins JB
Pediatr Phys Ther 2023 Apr 1;35(2):202-210. Epub 2023 Mar 3 doi: 10.1097/PEP.0000000000000999. PMID: 36867588
Sileo FG, Zöllner J, D'Antonio F, Islam S, Papageorghiou AT, Khalil A
Ultrasound Obstet Gynecol 2022 May;59(5):585-595. doi: 10.1002/uog.24766. PMID: 34529308
Medeiros KS, Macêdo LTA, Souza WF, Sarmento AC, Costa APF, Gonçalves AK
Rev Assoc Med Bras (1992) 2021 Feb;67(2):318-334. doi: 10.1590/1806-9282.67.2.20200716. PMID: 34406260
Reid SM, Carlin JB, Reddihough DS
Res Dev Disabil 2011 Nov-Dec;32(6):2909-15. Epub 2011 May 31 doi: 10.1016/j.ridd.2011.05.012. PMID: 21624819
Rogers A, Furler BL, Brinks S, Darrah J
Dev Med Child Neurol 2008 Nov;50(11):808-14. Epub 2008 Sep 22 doi: 10.1111/j.1469-8749.2008.03134.x. PMID: 18811714

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