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Eccrine acrospiroma

MedGen UID:
104915
•Concept ID:
C0206671
•
Neoplastic Process
Synonyms: Acrospiroma, Eccrine; Eccrine Acrospiroma; Eccrine Acrospiromas; Eccrine Spiradenoma; Eccrine Spiradenomas; Spiradenoma, Eccrine; Spiradenomas, Eccrine
SNOMED CT: Eccrine acrospiroma (81143000); Eccrine hidradenoma (400099008); Apocrine nodular hidradenoma (400099008); Eccrine hidradenoma of skin (400099008); Solid-cystic hidradenoma (400099008); Eccrine nodular hidradenoma (400099008); Eccrine acrospiroma (400099008); Nodular hidradenoma (81143000); Nodular hidradenoma (253020008)
 
Monarch Initiative: MONDO:0006738

Definition

A benign epithelial neoplasm arising from the sweat glands. It presents as a nodular lesion usually in the scalp, trunk, and proximal extremities. It is characterized by a nodular growth pattern. Complete excision is curative. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEccrine acrospiroma

Professional guidelines

PubMed

Challenges in diagnosis and management of a spiradenocarcinoma: a comprehensive literature review.
Wagner K, Jassal K, Lee JC, Ban EJ, Cameron R, Serpell J
ANZ J Surg 2021 Oct;91(10):1996-2001. Epub 2021 Feb 1 doi: 10.1111/ans.16626. PMID: 33522696
The differential diagnosis of syringoma and milia based on the imaging of reflectance confocal microscopy.
Gao M, Lin Y, Wang L, Yu Y, Zhou Y, Chen S, Lu X, Shan X, Liu H
Skin Res Technol 2020 Nov;26(6):951-953. Epub 2020 Jun 14 doi: 10.1111/srt.12879. PMID: 32537748
Evaluation and management of the patient with multiple syringomas: A systematic review of the literature.
Williams K, Shinkai K
J Am Acad Dermatol 2016 Jun;74(6):1234-1240.e9. Epub 2016 Feb 3 doi: 10.1016/j.jaad.2015.12.006. PMID: 26850654

Recent clinical studies

Etiology

Adnexal skin tumors in Zaria, Nigeria.
Samaila MO
Ann Afr Med 2008 Mar;7(1):6-10. doi: 10.4103/1596-3519.55691. PMID: 18702242
Spectrum of cutaneous appendage tumors at Aga Khan University Hospital.
Yaqoob N, Ahmad Z, Muzaffar S, Gill MS, Soomro IN, Hasan SH
J Pak Med Assoc 2003 Sep;53(9):427-31. PMID: 14620320
Papillary transitional cell carcinoma of the breast: a report of five cases with distinction from eccrine acrospiroma.
Mooney EE, Tavassoli FA
Mod Pathol 1999 Mar;12(3):287-94. PMID: 10102614
Eccrine acrospiroma in a young African male: case report.
Nmadu PT
East Afr Med J 1995 Sep;72(9):613-4. PMID: 7498053
Clear cell eccrine carcinomas of the skin. A clinicopathologic study of nine patients.
Wong TY, Suster S, Nogita T, Duncan LM, Dickersin RG, Mihm MC Jr
Cancer 1994 Mar 15;73(6):1631-43. doi: 10.1002/1097-0142(19940315)73:6<1631::aid-cncr2820730615>3.0.co;2-7. PMID: 7512435

Diagnosis

Clinical and morphological features of eccrine acrospiroma: analysis of literature data and case from practice.
Myroshnychenko MS, Sakal HO, Pasiyeshvili NM, Kapustnyk NV, Kucheriavchenko MO, Kotenko OE, Maistrenko IO, Sirenko VA
Wiad Lek 2024;77(5):1101-1105. doi: 10.36740/WLek202405134. PMID: 39008604
Recurrent Eccrine Acrospiroma of the Parotid Region: A Case Report.
Gupta V, Mishra UP, Behera G
JNMA J Nepal Med Assoc 2021 Dec 11;59(244):1307-1309. doi: 10.31729/jnma.5702. PMID: 35199797Free PMC Article
Adnexal skin tumors in Zaria, Nigeria.
Samaila MO
Ann Afr Med 2008 Mar;7(1):6-10. doi: 10.4103/1596-3519.55691. PMID: 18702242
Assessment of cellular proliferation of eccrine acrospiromas and eccrine sweat gland carcinomas by AgNOR counting and immunohistochemical demonstration of proliferating cell nuclear antigen (PCNA) and Ki-67.
Ansai S, Koseki S, Hozumi Y, Kondo S
Clin Exp Dermatol 1995 Jan;20(1):27-34. doi: 10.1111/j.1365-2230.1995.tb01278.x. PMID: 7671392
Clear cell eccrine carcinomas of the skin. A clinicopathologic study of nine patients.
Wong TY, Suster S, Nogita T, Duncan LM, Dickersin RG, Mihm MC Jr
Cancer 1994 Mar 15;73(6):1631-43. doi: 10.1002/1097-0142(19940315)73:6<1631::aid-cncr2820730615>3.0.co;2-7. PMID: 7512435

Prognosis

Assessment of cellular proliferation of eccrine acrospiromas and eccrine sweat gland carcinomas by AgNOR counting and immunohistochemical demonstration of proliferating cell nuclear antigen (PCNA) and Ki-67.
Ansai S, Koseki S, Hozumi Y, Kondo S
Clin Exp Dermatol 1995 Jan;20(1):27-34. doi: 10.1111/j.1365-2230.1995.tb01278.x. PMID: 7671392
Eccrine acrospiroma in a young African male: case report.
Nmadu PT
East Afr Med J 1995 Sep;72(9):613-4. PMID: 7498053
Eccrine adenocarcinoma--report of a case, treatment with Mohs surgery.
Dzubow LM, Grossman DJ, Johnson B
J Dermatol Surg Oncol 1986 Oct;12(10):1049-53. doi: 10.1111/j.1524-4725.1986.tb02082.x. PMID: 3760312

Clinical prediction guides

Assessment of cellular proliferation of eccrine acrospiromas and eccrine sweat gland carcinomas by AgNOR counting and immunohistochemical demonstration of proliferating cell nuclear antigen (PCNA) and Ki-67.
Ansai S, Koseki S, Hozumi Y, Kondo S
Clin Exp Dermatol 1995 Jan;20(1):27-34. doi: 10.1111/j.1365-2230.1995.tb01278.x. PMID: 7671392

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