U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Myocardial stunning

MedGen UID:
61526
•Concept ID:
C0206146
•
Disease or Syndrome
Synonyms: Myocardial Stunning; Stunning, Myocardial
 
Monarch Initiative: MONDO:0004876

Definition

Prolonged dysfunction of the myocardium after a brief episode of severe ischemia, with gradual return of contractile activity. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMyocardial stunning

Professional guidelines

PubMed

Stress Cardiomyopathy Diagnosis and Treatment: JACC State-of-the-Art Review.
Medina de Chazal H, Del Buono MG, Keyser-Marcus L, Ma L, Moeller FG, Berrocal D, Abbate A
J Am Coll Cardiol 2018 Oct 16;72(16):1955-1971. doi: 10.1016/j.jacc.2018.07.072. PMID: 30309474Free PMC Article
Takotsubo Syndrome: Clinical Features, Pathogenesis, Treatment, and Relationship with Cerebrovascular Diseases.
Ranieri M, Finsterer J, Bedini G, Parati EA, Bersano A
Curr Neurol Neurosci Rep 2018 Mar 22;18(5):20. doi: 10.1007/s11910-018-0833-7. PMID: 29569186
Intensive Hemodialysis and Treatment Complications and Tolerability.
Morfin JA, Fluck RJ, Weinhandl ED, Kansal S, McCullough PA, Komenda P
Am J Kidney Dis 2016 Nov;68(5S1):S43-S50. doi: 10.1053/j.ajkd.2016.05.021. PMID: 27772642

Recent clinical studies

Etiology

From Neurocardiology to Stroke-Heart Syndrome.
Nistor IR, Gherasim L
Rom J Intern Med 2023 Dec 1;61(4):177-185. Epub 2023 Aug 4 doi: 10.2478/rjim-2023-0020. PMID: 37540842
Stress Cardiomyopathy Diagnosis and Treatment: JACC State-of-the-Art Review.
Medina de Chazal H, Del Buono MG, Keyser-Marcus L, Ma L, Moeller FG, Berrocal D, Abbate A
J Am Coll Cardiol 2018 Oct 16;72(16):1955-1971. doi: 10.1016/j.jacc.2018.07.072. PMID: 30309474Free PMC Article
Current interpretation of myocardial stunning.
Guaricci AI, Bulzis G, Pontone G, Scicchitano P, Carbonara R, Rabbat M, De Santis D, Ciccone MM
Trends Cardiovasc Med 2018 May;28(4):263-271. Epub 2017 Nov 27 doi: 10.1016/j.tcm.2017.11.005. PMID: 29221768
Carbon monoxide-induced cardiomyopathy.
Jung YS, Lee JS, Min YG, Park JS, Jeon WC, Park EJ, Shin JH, Oh S, Choi SC
Circ J 2014;78(6):1437-44. Epub 2014 Apr 4 doi: 10.1253/circj.cj-13-1282. PMID: 24705389
Intracranial hemorrhage.
Naidech AM
Am J Respir Crit Care Med 2011 Nov 1;184(9):998-1006. doi: 10.1164/rccm.201103-0475CI. PMID: 22167847Free PMC Article

Diagnosis

Current interpretation of myocardial stunning.
Guaricci AI, Bulzis G, Pontone G, Scicchitano P, Carbonara R, Rabbat M, De Santis D, Ciccone MM
Trends Cardiovasc Med 2018 May;28(4):263-271. Epub 2017 Nov 27 doi: 10.1016/j.tcm.2017.11.005. PMID: 29221768
Cardiovascular Abnormalities in Carbon Monoxide Poisoning.
Garg J, Krishnamoorthy P, Palaniswamy C, Khera S, Ahmad H, Jain D, Aronow WS, Frishman WH
Am J Ther 2018 May/Jun;25(3):e339-e348. doi: 10.1097/MJT.0000000000000016. PMID: 24518173
Neurogenic stunned myocardium in subarachnoid hemorrhage.
Kerro A, Woods T, Chang JJ
J Crit Care 2017 Apr;38:27-34. Epub 2016 Oct 20 doi: 10.1016/j.jcrc.2016.10.010. PMID: 27837689
Takotsubo Syndrome and Embolic Events.
El-Battrawy I, Borggrefe M, Akin I
Heart Fail Clin 2016 Oct;12(4):543-50. Epub 2016 Jul 30 doi: 10.1016/j.hfc.2016.06.011. PMID: 27638024
Intracranial hemorrhage.
Naidech AM
Am J Respir Crit Care Med 2011 Nov 1;184(9):998-1006. doi: 10.1164/rccm.201103-0475CI. PMID: 22167847Free PMC Article

Therapy

Hemodialysis-Induced Myocardial Stunning: A Review.
Brown M, Burrows L, Pruett T, Burrows T
Nephrol Nurs J 2015 Jan-Feb;42(1):59-66; quiz 67. PMID: 26290919
Carbon monoxide-induced cardiomyopathy.
Jung YS, Lee JS, Min YG, Park JS, Jeon WC, Park EJ, Shin JH, Oh S, Choi SC
Circ J 2014;78(6):1437-44. Epub 2014 Apr 4 doi: 10.1253/circj.cj-13-1282. PMID: 24705389
Catecholamine-induced cardiomyopathy.
Kassim TA, Clarke DD, Mai VQ, Clyde PW, Mohamed Shakir KM
Endocr Pract 2008 Dec;14(9):1137-49. doi: 10.4158/EP.14.9.1137. PMID: 19158054
Myocardial bridging.
Alegria JR, Herrmann J, Holmes DR Jr, Lerman A, Rihal CS
Eur Heart J 2005 Jun;26(12):1159-68. Epub 2005 Mar 11 doi: 10.1093/eurheartj/ehi203. PMID: 15764618
The open-artery hypothesis.
Solomon A, Gersh B
Annu Rev Med 1998;49:63-76. doi: 10.1146/annurev.med.49.1.63. PMID: 9509249

Prognosis

Myocardial stunning and hibernation revisited.
Heusch G
Nat Rev Cardiol 2021 Jul;18(7):522-536. Epub 2021 Feb 2 doi: 10.1038/s41569-021-00506-7. PMID: 33531698
Stress Cardiomyopathy Diagnosis and Treatment: JACC State-of-the-Art Review.
Medina de Chazal H, Del Buono MG, Keyser-Marcus L, Ma L, Moeller FG, Berrocal D, Abbate A
J Am Coll Cardiol 2018 Oct 16;72(16):1955-1971. doi: 10.1016/j.jacc.2018.07.072. PMID: 30309474Free PMC Article
Intracranial hemorrhage.
Naidech AM
Am J Respir Crit Care Med 2011 Nov 1;184(9):998-1006. doi: 10.1164/rccm.201103-0475CI. PMID: 22167847Free PMC Article
Catecholamine-induced cardiomyopathy.
Kassim TA, Clarke DD, Mai VQ, Clyde PW, Mohamed Shakir KM
Endocr Pract 2008 Dec;14(9):1137-49. doi: 10.4158/EP.14.9.1137. PMID: 19158054
Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction.
Prasad A, Lerman A, Rihal CS
Am Heart J 2008 Mar;155(3):408-17. Epub 2008 Jan 31 doi: 10.1016/j.ahj.2007.11.008. PMID: 18294473

Clinical prediction guides

Myocardial stunning and hibernation revisited.
Heusch G
Nat Rev Cardiol 2021 Jul;18(7):522-536. Epub 2021 Feb 2 doi: 10.1038/s41569-021-00506-7. PMID: 33531698
Brain-Heart Interactions in Traumatic Brain Injury.
El-Menyar A, Goyal A, Latifi R, Al-Thani H, Frishman W
Cardiol Rev 2017 Nov/Dec;25(6):279-288. doi: 10.1097/CRD.0000000000000167. PMID: 28984668
Exploring the Pathophysiology of Takotsubo Cardiomyopathy.
Chen W, Dilsizian V
Curr Cardiol Rep 2017 Jun;19(6):53. doi: 10.1007/s11886-017-0865-7. PMID: 28439851
Psychosocial and psychoneuroendocrinal aspects of Takotsubo syndrome.
Kastaun S, Gerriets T, Tschernatsch M, Yeniguen M, Juenemann M
Nat Rev Cardiol 2016 Nov;13(11):688-694. Epub 2016 Jul 14 doi: 10.1038/nrcardio.2016.108. PMID: 27411402
Intracranial hemorrhage.
Naidech AM
Am J Respir Crit Care Med 2011 Nov 1;184(9):998-1006. doi: 10.1164/rccm.201103-0475CI. PMID: 22167847Free PMC Article

Recent systematic reviews

Effect of Intradialytic Exercise on Cardiovascular Outcomes in Maintenance Hemodialysis: A Systematic Review and Meta-Analysis.
Verrelli D, Sharma A, Alexiuk J, Tays Q, Rossum K, Sharma M, Ford E, Iansavitchene A, Al-Jaishi AA, Whitlock R, McIntyre CW, Garg AX, Bohm C
Kidney360 2024 Mar 1;5(3):390-413. Epub 2024 Feb 2 doi: 10.34067/KID.0000000000000361. PMID: 38306116Free PMC Article
Clinical features, complications, and outcomes of exogenous and endogenous catecholamine-triggered Takotsubo syndrome: A systematic review and meta-analysis of 156 published cases.
Y-Hassan S, Falhammar H
Clin Cardiol 2020 May;43(5):459-467. Epub 2020 Mar 3 doi: 10.1002/clc.23352. PMID: 32125009Free PMC Article
The spectrum of acute cardiopulmonary events associated with multiple sclerosis exacerbations.
Valencia-Sanchez C, Goodman BP, Carter JL, Wingerchuk DM
Mult Scler 2019 May;25(6):758-765. Epub 2019 Jan 18 doi: 10.1177/1352458518823482. PMID: 30657008
CMR imaging for the evaluation of myocardial stunning after acute myocardial infarction: a meta-analysis of prospective trials.
Romero J, Kahan J, Kelesidis I, Makani H, Wever-Pinzon O, Medina H, Garcia MJ
Eur Heart J Cardiovasc Imaging 2013 Nov;14(11):1080-91. Epub 2013 Apr 10 doi: 10.1093/ehjci/jet040. PMID: 23575990
CMR imaging assessing viability in patients with chronic ventricular dysfunction due to coronary artery disease: a meta-analysis of prospective trials.
Romero J, Xue X, Gonzalez W, Garcia MJ
JACC Cardiovasc Imaging 2012 May;5(5):494-508. doi: 10.1016/j.jcmg.2012.02.009. PMID: 22595157

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...