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Complete unilateral cleft lip

MedGen UID:
510610
Concept ID:
C0158651
Congenital Abnormality
HPO: HP:5201001

Definition

Unilateral cleft lip cleft that starts from the bottom of the upper lip and reaches the nasal cavity. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVComplete unilateral cleft lip

Professional guidelines

PubMed

Stonehouse-Smith D, Rahman ANAA, Mooney J, Bellardie H
Cleft Palate Craniofac J 2022 Jan;59(1):79-85. Epub 2021 Mar 24 doi: 10.1177/1055665621996116. PMID: 33757373
Pai BCJ, Hung YT, Wang RSH, Lo LJ
Plast Reconstr Surg 2019 Feb;143(2):359e-367e. doi: 10.1097/PRS.0000000000005216. PMID: 30531628
Mui Lee L, Ma L, Jun Li T
Cleft Palate Craniofac J 2017 May;54(3):338-342. doi: 10.1597/14-323. PMID: 28471735

Recent clinical studies

Etiology

Ritto FG, Mealy T, Canellas JV, Padwa BL, Smith KS
J Oral Maxillofac Surg 2023 Nov;81(11):1344-1352. Epub 2023 Aug 9 doi: 10.1016/j.joms.2023.08.003. PMID: 37640235
Van Slyke AC, Chong DK
J Craniofac Surg 2022 Mar-Apr 01;33(2):380-384. doi: 10.1097/SCS.0000000000008277. PMID: 35385902Free PMC Article
Murawski EL, Gawrych EH, Cutting CB, Sifakis ED, Wang Q, Tao Y
Plast Reconstr Surg 2022 Feb 1;149(2):254e-260e. doi: 10.1097/PRS.0000000000008788. PMID: 35077424
Staudt CB, Bollhalder J, Eichenberger M, La Scala G, Herzog G, Wiedemeier DB, Antonarakis GS
Cleft Palate Craniofac J 2022 Jul;59(7):899-909. Epub 2021 Jul 8 doi: 10.1177/10556656211028506. PMID: 34235980Free PMC Article
Grewal JS, Yanik SC, Strohl-Bryan AM, Tatum SA
Am J Otolaryngol 2021 May-Jun;42(3):102908. Epub 2021 Jan 13 doi: 10.1016/j.amjoto.2021.102908. PMID: 33508593

Diagnosis

Thakur S, Singh A, Diwana VK, Rani A, Thakur NS
Afr J Paediatr Surg 2020 Jan-Jun;17(1-2):1-4. doi: 10.4103/ajps.AJPS_5_18. PMID: 33106444Free PMC Article
Pai BCJ, Hung YT, Wang RSH, Lo LJ
Plast Reconstr Surg 2019 Feb;143(2):359e-367e. doi: 10.1097/PRS.0000000000005216. PMID: 30531628
Vyloppilli S, Krishnakumar KS, Sayd S, Latheef S, Narayanan SV, Pati A
J Plast Reconstr Aesthet Surg 2017 Nov;70(11):1614-1619. Epub 2017 Jun 9 doi: 10.1016/j.bjps.2017.05.052. PMID: 28676318
Semb G, Enemark H, Friede H, Paulin G, Lilja J, Rautio J, Andersen M, Åbyholm F, Lohmander A, Shaw W, Mølsted K, Heliövaara A, Bolund S, Hukki J, Vindenes H, Davenport P, Arctander K, Larson O, Berggren A, Whitby D, Leonard A, Neovius E, Elander A, Willadsen E, Bannister RP, Bradbury E, Henningsson G, Persson C, Eyres P, Emborg B, Kisling-Møller M, Küseler A, Granhof Black B, Schöps A, Bau A, Boers M, Andersen HS, Jeppesen K, Marxen D, Paaso M, Hölttä E, Alaluusua S, Turunen L, Humerinta K, Elfving-Little U, Tørdal IB, Kjøll L, Aukner R, Hide Ø, Feragen KB, Rønning E, Skaare P, Brinck E, Semmingsen AM, Lindberg N, Bowden M, Davies J, Mooney J, Bellardie H, Schofield N, Nyberg J, Lundberg M, Karsten AL, Larson M, Holmefjord A, Reisæter S, Pedersen NH, Rasmussen T, Tindlund R, Sæle P, Blomhoff R, Jacobsen G, Havstam C, Rizell S, Enocson L, Hagberg C, Najar Chalien M, Paganini A, Lundeborg I, Marcusson A, Mjönes AB, Gustavsson A, Hayden C, McAleer E, Slevan E, Gregg T, Worthington H
J Plast Surg Hand Surg 2017 Feb;51(1):2-13. doi: 10.1080/2000656X.2016.1263202. PMID: 28218559
Rautio J, Andersen M, Bolund S, Hukki J, Vindenes H, Davenport P, Arctander K, Larson O, Berggren A, Åbyholm F, Whitby D, Leonard A, Lilja J, Neovius E, Elander A, Heliövaara A, Eyres P, Semb G
J Plast Surg Hand Surg 2017 Feb;51(1):14-20. doi: 10.1080/2000656X.2016.1254646. PMID: 28218552

Therapy

Thiruvenkatachari B, Chakkaravarthi S, Prathap M, Naveed N, Bhuvaraghan A
Orthod Craniofac Res 2024 Jun;27 Suppl 1:90-99. Epub 2023 Dec 18 doi: 10.1111/ocr.12744. PMID: 38108550
Semb G, Enemark H, Friede H, Paulin G, Lilja J, Rautio J, Andersen M, Åbyholm F, Lohmander A, Shaw W, Mølsted K, Heliövaara A, Bolund S, Hukki J, Vindenes H, Davenport P, Arctander K, Larson O, Berggren A, Whitby D, Leonard A, Neovius E, Elander A, Willadsen E, Bannister RP, Bradbury E, Henningsson G, Persson C, Eyres P, Emborg B, Kisling-Møller M, Küseler A, Granhof Black B, Schöps A, Bau A, Boers M, Andersen HS, Jeppesen K, Marxen D, Paaso M, Hölttä E, Alaluusua S, Turunen L, Humerinta K, Elfving-Little U, Tørdal IB, Kjøll L, Aukner R, Hide Ø, Feragen KB, Rønning E, Skaare P, Brinck E, Semmingsen AM, Lindberg N, Bowden M, Davies J, Mooney J, Bellardie H, Schofield N, Nyberg J, Lundberg M, Karsten AL, Larson M, Holmefjord A, Reisæter S, Pedersen NH, Rasmussen T, Tindlund R, Sæle P, Blomhoff R, Jacobsen G, Havstam C, Rizell S, Enocson L, Hagberg C, Najar Chalien M, Paganini A, Lundeborg I, Marcusson A, Mjönes AB, Gustavsson A, Hayden C, McAleer E, Slevan E, Gregg T, Worthington H
J Plast Surg Hand Surg 2017 Feb;51(1):2-13. doi: 10.1080/2000656X.2016.1263202. PMID: 28218559
Rautio J, Andersen M, Bolund S, Hukki J, Vindenes H, Davenport P, Arctander K, Larson O, Berggren A, Åbyholm F, Whitby D, Leonard A, Lilja J, Neovius E, Elander A, Heliövaara A, Eyres P, Semb G
J Plast Surg Hand Surg 2017 Feb;51(1):14-20. doi: 10.1080/2000656X.2016.1254646. PMID: 28218552
Bichara LM, Araújo RC, Flores-Mir C, Normando D
Int J Oral Maxillofac Surg 2015 Jan;44(1):50-6. Epub 2014 Sep 10 doi: 10.1016/j.ijom.2014.08.004. PMID: 25217008
Gosla Reddy S, Reddy RR, Bronkhorst EM, Prasad R, Kuijpers Jagtman AM, Bergé S
Plast Reconstr Surg 2010 Apr;125(4):1208-1216. doi: 10.1097/PRS.0b013e3181d45143. PMID: 20335871

Prognosis

Ritto FG, Mealy T, Canellas JV, Padwa BL, Smith KS
J Oral Maxillofac Surg 2023 Nov;81(11):1344-1352. Epub 2023 Aug 9 doi: 10.1016/j.joms.2023.08.003. PMID: 37640235
Murawski EL, Gawrych EH, Cutting CB, Sifakis ED, Wang Q, Tao Y
Plast Reconstr Surg 2022 Feb 1;149(2):254e-260e. doi: 10.1097/PRS.0000000000008788. PMID: 35077424
Vyloppilli S, Krishnakumar KS, Sayd S, Latheef S, Narayanan SV, Pati A
J Plast Reconstr Aesthet Surg 2017 Nov;70(11):1614-1619. Epub 2017 Jun 9 doi: 10.1016/j.bjps.2017.05.052. PMID: 28676318
Rautio J, Andersen M, Bolund S, Hukki J, Vindenes H, Davenport P, Arctander K, Larson O, Berggren A, Åbyholm F, Whitby D, Leonard A, Lilja J, Neovius E, Elander A, Heliövaara A, Eyres P, Semb G
J Plast Surg Hand Surg 2017 Feb;51(1):14-20. doi: 10.1080/2000656X.2016.1254646. PMID: 28218552
Arshad AI, Alam MK, Khamis MF
Int J Pediatr Otorhinolaryngol 2017 Jan;92:70-74. Epub 2016 Nov 11 doi: 10.1016/j.ijporl.2016.11.006. PMID: 28012538

Clinical prediction guides

Alforaidi S, Zreaqat M, Hassan R
J Contemp Dent Pract 2023 Dec 1;24(12):987-990. doi: 10.5005/jp-journals-10024-3606. PMID: 38317397
Ritto FG, Mealy T, Canellas JV, Padwa BL, Smith KS
J Oral Maxillofac Surg 2023 Nov;81(11):1344-1352. Epub 2023 Aug 9 doi: 10.1016/j.joms.2023.08.003. PMID: 37640235
Van Slyke AC, Chong DK
J Craniofac Surg 2022 Mar-Apr 01;33(2):380-384. doi: 10.1097/SCS.0000000000008277. PMID: 35385902Free PMC Article
Staudt CB, Bollhalder J, Eichenberger M, La Scala G, Herzog G, Wiedemeier DB, Antonarakis GS
Cleft Palate Craniofac J 2022 Jul;59(7):899-909. Epub 2021 Jul 8 doi: 10.1177/10556656211028506. PMID: 34235980Free PMC Article
Grewal JS, Yanik SC, Strohl-Bryan AM, Tatum SA
Am J Otolaryngol 2021 May-Jun;42(3):102908. Epub 2021 Jan 13 doi: 10.1016/j.amjoto.2021.102908. PMID: 33508593

Recent systematic reviews

Thiruvenkatachari B, Chakkaravarthi S, Prathap M, Naveed N, Bhuvaraghan A
Orthod Craniofac Res 2024 Jun;27 Suppl 1:90-99. Epub 2023 Dec 18 doi: 10.1111/ocr.12744. PMID: 38108550
Salgado KR, Wendt AR, Fernandes Fagundes NC, Maia LC, Normando D, Leão PB
J Craniomaxillofac Surg 2019 Nov;47(11):1690-1698. Epub 2019 Jul 3 doi: 10.1016/j.jcms.2019.06.017. PMID: 31677987
Bichara LM, Araújo RC, Flores-Mir C, Normando D
Int J Oral Maxillofac Surg 2015 Jan;44(1):50-6. Epub 2014 Sep 10 doi: 10.1016/j.ijom.2014.08.004. PMID: 25217008

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